Ετικέτες

Τρίτη 20 Μαρτίου 2018

Multifunctional manganese-doped Prussian blue nanoparticles for two-photon photothermal therapy and magnetic resonance imaging

Publication date: June 2018
Source:Photodiagnosis and Photodynamic Therapy, Volume 22
Author(s): Lamiaa M.A. Ali, Emna Mathlouthi, Marilyn Kajdan, Morgane Daurat, Jérôme Long, Rahima Sidi-Boulenouar, Maïda Cardoso, Christophe Goze-Bac, Nourredine Amdouni, Yannick Guari, Joulia Larionova, Magali Gary-Bobo
Here we demonstrate for the first time that Mn2+-doped Prussian blue nanoparticles of c.a. 70 nm act as effective agents for photothermal therapy under two-photon excitation with an almost total eradication of malignant cells (97 and 98%) at a concentration of 100 μg mL−1 24 h after NIR excitation. This effect combined with interesting longitudinal NMR relaxivity values offer new perspectives for effective imaging and cancer treatment.

Graphical abstract

image


http://ift.tt/2IH4QO3

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αναζήτηση αυτού του ιστολογίου