Weight Loss and Adipose Tissue Browning in Humans: The Chicken or the Egg?

Publication date: Available online 13 March 2018
Source:Trends in Endocrinology & Metabolism
Author(s): Lucia Balazova, Christian Wolfrum, Miroslav Balaz
Recruitment of thermogenic adipocytes within white fat depots represents a promising strategy to increase energy expenditure. Negative energy balance has been reported to promote adipose tissue browning in rodents. In a recent issue of Cell Reports, Barquissau et al. show that caloric restriction-associated weight loss does not induce browning of subcutaneous abdominal white fat in obese humans.



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