Photodynamic therapy with the use of superluminescent diodes (sLED) in the treatment of actinic keratosis

Publication date: Available online 22 April 2018
Source:Photodiagnosis and Photodynamic Therapy
Author(s): Joanna Bartosińska, Katarzyna Wolska, Agnieszka Gerkowicz, Marta Niewiedzioł, Małgorzata Michalska - Jakubus, Małgorzata Komza, Tomasz Klepaczewski, Mirosław Kwaśny, Dorota Krasowska
BackgroundSuperluminescent diodes (sLED) appear to be an innovative and promising light source in photodynamic therapy (PDT), especially in actinic keratosis (AK) lesions treatment.AimAssessment of tolerability and efficacy of sLED in topical 5-aminolevulinic acid (ALA) PDT of AK lesions.Methods27 patients received ALA PDT with the use of sLED with "soft starter".ResultsTolerability of sLED lamp depended on the treated lesions field (extension) rather than on their thickness. In contrast sLED lamp efficacy depended on AK lesions thickness.ConclusionsLED PDT is highly effective in the treatment of grade I and II AK lesions. Grade III AK lesions require further treatment.



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