Role of Fractionated Fat (FractoFat) in Blending the Lid-Cheek Junction

Introduction: Fat grafting is extensively used in plastic surgery in last 2 decades. Here, we report the retrospective comparison of patients who underwent fractionated fat injection to blend the lid-cheek junction with those who had regular fat injection. Method: After obtaining institutional review board approval, a retrospective review of patients who underwent lower blepharoplasty with fractionated fat injection for blending lid-cheek junction from January 2014 through October 2015 was performed. The results were compared to lower blepharoplasty patients who didn't have fractionated fat injected prior to January 2014.Twelve prospectively selected patients underwent histopathological and gene expression comparisons. Results: A comparison of complications between 2 groups revealed no significant difference. Furthermore, there was no significant difference between 2 groups for sequelae of fractionated fat injection and regular fat injection. The gene expression analysis of the fractionated and regular fat didn't have any difference with both undifferentiated and differentiated cells. Additionally, Oil Red O staining of the fractionated and regular fat after differentiation shows that cells from both kinds of fat groups differentiated equally well. Conclusion: Fractionated fat injection appears to be safe addition in blending the lid-cheek junction in the five step lower blepharoplasty. There is no fat nodule formation with injection of fractionated fat injection in comparison to injection of regular fat done superficially in the tear trough area. Contrary to what has previously been shown, the presence of viable cells in fractionated fat was noted. Disclosure: The authors have no financial interest to declare in relation to the content of this article. Dr. Rohrich receives instrument royalties from Micrins Instruments and book royalties from Thieme Publishers Corresponding author: Rod J. Rohrich, MD, Dallas Plastic Surgery Institute, 1901 North Central Expressway; Suite 600, Dallas, Texas 75230, Rod.rohrich@dpsi.org ©2018American Society of Plastic Surgeons

https://ift.tt/2JEt4fp