Apparent Diffusion Coefficient (ADC) and Susceptibility Weighted Imaging (SWI) of the vitreous humor in abused children with retinal hemorrhages

Publication date: Available online 3 April 2017
Source:Clinical Imaging
Author(s): Misun Hwang, Samuel S. Shin, Matthew A. Thimm, Anish Ghodadra, Christin L. Sylvester, Ken Nischal, Ashok Panigrahy, Giulio Zuccoli
This study speculated that the apparent diffusion coefficient (ADC) of the vitreous humor might be altered in the setting of abusive head trauma (AHT) with retinal hemorrhages (RH). Fourty-four subjects were analyzed (n=20 AHT cases; n=24 controls). There was no statistically significant difference in normalized ADC values between the cases and controls (−0.14 and −0.08 respectively, p=0.46), but analysis of RH by susceptibility weighted imaging (SWI) compared to dilated funduscopic exam demonstrated statistically significant correlation (p=0.003 and 0.012). Our results suggest that SWI serves as a more sensitive diagnostic tool for detection of RH in AHT than ADC.



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