Publication date: Available online 9 May 2017
Source:Trends in Endocrinology & Metabolism
Author(s): Anthony R. Isles
Serotonin 2C receptor (5HT2CR) exists as different isoforms as a result of alternate splicing. A truncated variant (5HT2CR-trunc) has no canonical receptor function and yet shows robust expression levels throughout the brain. Recent work has demonstrated the biochemical role of this isoform and how altering levels of 5HT2CR-trunc leads to changes in behaviour.
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Τετάρτη 10 Μαΐου 2017
Htr2c Splice Variants and 5HT2CR-Mediated Appetite
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Publication date: January–February 2018 Source: Materials Today, Volume 21, Issue 1 Author(s): David Bradley http://ift.tt/2BP...
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Summary 银屑病是一种常见的皮肤病,影响北欧国家大约 5‐10% 的人口和全世界超过 1.25 亿人。已证实此病与治疗依从性低(意味着人们不能坚持他们的治疗)、不健康的生活方式(例如抽烟、饮酒、体育活动减少)和因此而产生的代谢性疾病相关。银屑病患者中的抑郁频率更高,但关于...
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