IJMS, Vol. 21, Pages 7745: Revisiting Ionic Liquid Structure-Property Relationship: A Critical Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21207745 Authors: Silva Zanatta Ferreira Corvo Cabrita In the last few years, ionic liquids (ILs) have been the focus of extensive studies concerning the relationship between structure and properties and how this impacts their application. Despite a large number of studies, several topics remain controversial...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7744: Exogenous Application of Proteoglycan to the Cell Surface Microenvironment Facilitates to Chondrogenic Differentiation and Maintenance International Journal of Molecular Sciences doi: 10.3390/ijms21207744 Authors: Masutani Yamada Hara Takahashi Green Niwa Osteoarthritis (OA), a disease that greatly impacts quality of life, has increasing worldwide prevalence as the population ages. However, its pathogenic mechanisms have not been fully...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7739: The Glucose Metabolic Pathway as A Potential Target for Therapeutics: Crucial Role of Glycosylation in Alzheimer’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21207739 Authors: Vidyasagar Naik Bukke Rosanna Villani Moola Archana Agata Wawrzyniak Krzysztof Balawender Stanislaw Orkisz Luca Ferraro Gaetano Serviddio Tommaso Cassano Glucose uptake in the brain decreases because of normal aging but this decline is...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7743: Combination Immunotherapy Using Oncolytic Virus for the Treatment of Advanced Solid Tumors International Journal of Molecular Sciences doi: 10.3390/ijms21207743 Authors: Chang-Myung Oh Hong Jae Chon Chan Kim Oncolytic virus (OV) is a new therapeutic strategy for cancer treatment. OVs can selectively infect and destroy cancer cells, and therefore act as an in situ cancer vaccine by releasing tumor-specific antigens. Moreover, they can remodel the tumor...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7740: Taming the Sentinels: Microbiome-Derived Metabolites and Polarization of T Cells International Journal of Molecular Sciences doi: 10.3390/ijms21207740 Authors: Lukasz Wojciech Kevin S. W. Tan Nicholas R. J. Gascoigne A global increase in the prevalence of metabolic syndromes and digestive tract disorders, like food allergy or inflammatory bowel disease (IBD), has become a severe problem in the modern world. Recent decades have brought a growing body of...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7738: In Vivo, In Vitro and In Silico Studies of the Hybrid Compound AA3266, an Opioid Agonist/NK1R Antagonist with Selective Cytotoxicity International Journal of Molecular Sciences doi: 10.3390/ijms21207738 Authors: Joanna Matalińska Piotr F.J. Lipiński Piotr Kosson Katarzyna Kosińska Aleksandra Misicka AA3266 is a hybrid compound consisting of opioid receptor agonist and neurokinin-1 receptor (NK1R) antagonist pharmacophores. It was designed with the...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7741: Interferon-Mediated Long Non-Coding RNA Response in Macrophages in the Context of HIV International Journal of Molecular Sciences doi: 10.3390/ijms21207741 Authors: Tinus Schynkel Matthew A. Szaniawski Adam M. Spivak Alberto Bosque Vicente Planelles Linos Vandekerckhove Wim Trypsteen Interferons play a critical role in the innate immune response against a variety of pathogens, such as HIV-1. Recent studies have shown that long non-coding genes...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7736: Impact of Dim Light at Night on Urinary 6-Sulphatoxymelatonin Concentrations and Sleep in Healthy Humans International Journal of Molecular Sciences doi: 10.3390/ijms21207736 Authors: Katarina Stebelova Jan Roska Michal Zeman Artificial light at night can have negative effects on human wellbeing and health. It can disrupt circadian rhythms, interfere with sleep, and participate in the progress of civilisation diseases. The aim of the present study was...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7737: Heregulin Drives Endocrine Resistance by Altering IL-8 Expression in ER-Positive Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21207737 Authors: Adriana Papadimitropoulou Luciano Vellon Ella Atlas Travis Vander Steen Elisabet Cuyàs Sara Verdura Ingrid Espinoza Javier A. Menendez Ruth Lupu Sustained HER2/HER3 signaling due to the overproduction of the HER3 ligand heregulin (HRG) is proposed as a key contributor...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7734: Overexpression of PtrMYB121 Positively Regulates the Formation of Secondary Cell Wall in Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms21207734 Authors: Ying Liu Jiayin Man Yinghao Wang Chao Yuan Yuyu Shi Bobin Liu Xia Hu Songqing Wu Taoxiang Zhang Chunlan Lian MYB transcription factors have a wide range of functions in plant growth, hormone signaling, salt, and drought tolerances. In this study,...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7733: The N-Terminal Region of Yeast Protein Phosphatase Ppz1 Is a Determinant for Its Toxicity International Journal of Molecular Sciences doi: 10.3390/ijms21207733 Authors: Carlos Calafí María López-Malo Marcel Albacar Antonio Casamayor Joaquín Ariño The Ppz enzymes are Ser/Thr protein phosphatases present only in fungi that are characterized by a highly conserved C-terminal catalytic region, related to PP1c phosphatases, and a more divergent N-terminal...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7732: Insights into the Function and Evolution of Taste 1 Receptor Gene Family in the Carnivore Fish Gilthead Seabream (Sparus aurata) International Journal of Molecular Sciences doi: 10.3390/ijms21207732 Authors: Anna Rita Angotzi Sara Puchol Jose M. Cerdá-Reverter Sofia Morais A plethora of molecular and functional studies in tetrapods has led to the discovery of multiple taste 1 receptor (T1R) genes encoding G-protein coupled receptors (GPCRs) responsible...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7735: DNA Methylation at Birth Predicts Intellectual Functioning and Autism Features in Children with Fragile X Syndrome International Journal of Molecular Sciences doi: 10.3390/ijms21207735 Authors: Claudine M Kraan Emma K Baker Marta Arpone Minh Bui Ling Ling Dinusha Gamage Lesley Bretherton Carolyn Rogers Michael J Field Tiffany L Wotton David Francis Matt F Hunter Jonathan Cohen David J Amor David E Godler Fragile X syndrome...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7731: Bone Regeneration Potential of Human Dental Pulp Stem Cells Derived from Elderly Patients and Osteo-Induced by a Helioxanthin Derivative International Journal of Molecular Sciences doi: 10.3390/ijms21207731 Authors: Marika Sato Yoko Kawase-Koga Daiki Yamakawa Yasuyuki Fujii Daichi Chikazu Human dental pulp stem cells (DPSCs) have high clonogenic and proliferative potential. We previously reported that a helioxanthin derivative (4-(4-methoxyphenyl)pyrido[40,30:4,5]thieno[2–b]pyridine-2-carboxamide...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7730: Human Amniotic Epithelial Stem Cells: A Promising Seed Cell for Clinical Applications International Journal of Molecular Sciences doi: 10.3390/ijms21207730 Authors: Chen Qiu Zhen Ge Wenyu Cui Luyang Yu Jinying Li Perinatal stem cells have been regarded as an attractive and available cell source for medical research and clinical trials in recent years. Multiple stem cell types have been identified in the human placenta. Recent advances in knowledge...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7726: Non-Muscle-Invasive Bladder Carcinoma with Respect to Basal Versus Luminal Keratin Expression International Journal of Molecular Sciences doi: 10.3390/ijms21207726 Authors: Jung Jang Kim Moon Non-muscle-invasive bladder cancer (NMIBC) consists of transcriptional subtypes that are distinguishable from those of muscle-invasive cancer. We aimed to identify genetic signatures of NMIBC related to basal (K5/6) and luminal (K20) keratin expression. Based...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7729: Dietary Energy Partition: The Central Role of Glucose International Journal of Molecular Sciences doi: 10.3390/ijms21207729 Authors: Xavier Remesar Marià Alemany Humans have developed effective survival mechanisms under conditions of nutrient (and energy) scarcity. Nevertheless, today, most humans face a quite different situation: excess of nutrients, especially those high in amino-nitrogen and energy (largely fat). The lack of mechanisms to prevent energy...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7727: Internalization of the Aspergillus nidulans AstA Transporter into Mitochondria Depends on Growth Conditions, and Affects ATP Levels and Sulfite Oxidase Activity International Journal of Molecular Sciences doi: 10.3390/ijms21207727 Authors: Sebastian Piłsyk Adam Mieczkowski Maciej P. Golan Agata Wawrzyniak Joanna S. Kruszewska The astA gene encoding an alternative sulfate transporter was originally cloned from the genome of the Japanese Aspergillus...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7728: Single-Dose Cisplatin Pre-Treatment Enhances Efficacy of ROBO1-Targeted Radioimmunotherapy International Journal of Molecular Sciences doi: 10.3390/ijms21207728 Authors: Fujiwara Koyama Tsuji Iwanari Kusano-Arai Higashi Momose Hamakubo We previously reported that radioimmunotherapy (RIT) using 90Y-labeled anti-ROBO1 IgG (90Y-B5209B) achieved significant anti-tumor effects against small-cell lung cancer (SCLC) xenografts. However,...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7722: Increased Pro-Thrombotic Platelet Activity Associated with Thrombin/PAR1-Dependent Pathway Disorder in Patients with Secondary Progressive Multiple Sclerosis International Journal of Molecular Sciences doi: 10.3390/ijms21207722 Authors: Angela Dziedzic Elzbieta Miller Michal Bijak Lukasz Przyslo Joanna Saluk-Bijak Epidemiological studies confirm the high risk of ischemic events in multiple sclerosis (MS) that are associated with increased pro-thrombotic...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7724: Effect of Silymarin Supplementation on Physical Performance, Muscle and Myocardium Histological Changes, Bodyweight, and Food Consumption in Rats Subjected to Regular Exercise Training International Journal of Molecular Sciences doi: 10.3390/ijms21207724 Authors: Nancy Vargas-Mendoza Marcelo Ángeles-Valencia Eduardo Osiris Madrigal-Santillán Mauricio Morales-Martínez Judith Margarita Tirado-Lule Arturo Solano-Urrusquieta Eduardo Madrigal-Bujaidar...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7725: Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder—Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection International Journal of Molecular Sciences doi: 10.3390/ijms21207725 Authors: Wenrui Li Xiaolu Guan Li Sun MicroRNAs (miRNAs) are small non-coding RNAs with important roles in diverse biological processes including immunity. Japanese flounder (Paralichthys olivaceus) is an aquaculture fish species susceptible to the...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7723: RAGE Up-Regulation Differently Affects Cell Proliferation and Migration in Pancreatic Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21207723 Authors: Priyanka Swami Swetha Thiyagarajan Arianna Vidger Venkata S. K. Indurthi Stefan W. Vetter Estelle Leclerc The receptor for advanced glycation end products (RAGE) contributes to many cellular aspects of pancreatic cancer including cell proliferation, migration, and survival....
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7721: Anti-Apolipoprotein A-1 IgG Influences Neutrophil Extracellular Trap Content at Distinct Regions of Human Carotid Plaques International Journal of Molecular Sciences doi: 10.3390/ijms21207721 Authors: Rafaela F. da Silva Daniela Baptista Aline Roth Kapka Miteva Fabienne Burger Nicolas Vuilleumier Federico Carbone Fabrizio Montecucco François Mach Karim J. Brandt Background: Neutrophils accumulate in atherosclerotic plaques. Neutrophil...
Mon Oct 19, 2020 03:00
IJMS, Vol. 21, Pages 7720: A Bioinformatic Pipeline Places STAT5A as a miR-650 Target in Poorly Differentiated Aggressive Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21207720 Authors: Eric López-Huerta Ezequiel M. Fuentes-Pananá Breast cancer (BRCA) is a leading cause of mortality among women. Tumors often acquire aggressive features through genomic aberrations affecting cellular programs, e.g., the epithelial to mesenchymal transition (EMT). EMT facilitates...
Mon Oct 19, 2020 03:00
JCM, Vol. 9, Pages 3353: Aging Is Positively Associated with Peri-Sinus Lymphatic Space Volume: Assessment Using 3T Black-Blood MRI Journal of Clinical Medicine doi: 10.3390/jcm9103353 Authors: Park Kim Ahn Cha Suh Objectives: Aging is a major risk factor for many neurological disorders and is associated with dural lymphatic dysfunction. We sought to evaluate the association of aging with the volume of the peri-sinus lymphatic space using contrast-enhanced 3T T1-weighted...
Mon Oct 19, 2020 03:00
JCM, Vol. 9, Pages 3355: Relative Skeletal Muscle Mass Is an Important Factor in Non-Alcoholic Fatty Liver Disease in Non-Obese Children and Adolescents Journal of Clinical Medicine doi: 10.3390/jcm9103355 Authors: Kwon Jeong Recently, sarcopenia was identified as a risk factor for non-alcoholic fatty liver disease (NAFLD) in adults. We here investigated the association between skeletal muscle mass (SMM) and NAFLD in non-obese children and adolescents. A retrospective medical chart...
Mon Oct 19, 2020 03:00
JCM, Vol. 9, Pages 3354: Decreased Cerebrospinal Fluid Orexin-A (Hypocretin-1) Concentrations in Patients after Generalized Convulsive Status Epilepticus Journal of Clinical Medicine doi: 10.3390/jcm9103354 Authors: Samzadeh Papuć Furtak-Niczyporuk Rejdak The effects of status epilepticus on the orexin/hypocretin system have yet to be investigated. The present study aimed to assay orexin-A/hypocretin-1 in the cerebrospinal fluid (CSF) of patients after generalized convulsive...
Mon Oct 19, 2020 03:00
JCM, Vol. 9, Pages 3356: Myocardial Infarction after Kidney Transplantation: A Risk and Specific Profile Analysis from a Nationwide French Medical Information Database Journal of Clinical Medicine doi: 10.3390/jcm9103356 Authors: Didier Yao Legendre Halimi Rebibou Herbert Zeller Fauchier Cottin Introduction: Renal transplant recipients have a high peri-operative risk for cardiovascular events. The post-transplantation period also carries a risk of myocardial...
Mon Oct 19, 2020 03:00
JCM, Vol. 9, Pages 3352: An Assessment of the Novel COVISTRESS Questionnaire: COVID-19 Impact on Physical Activity, Sedentary Action and Psychological Emotion Journal of Clinical Medicine doi: 10.3390/jcm9103352 Authors: Ukadike Ugbolue Martine Duclos Constanta Urzeala Mickael Berthon Keri Kulik Aura Bota David Thivel Reza Bagheri Yaodong Gu Julien Baker Nicolas Andant Bruno Pereira Karine Rouffiac Maëlys Clinchamps Frédéric Dutheil on behalf of...
Mon Oct 19, 2020 03:00
JCM, Vol. 9, Pages 3351: Creating Healthy Change in the Preconception Period for Women with Overweight or Obesity: A Qualitative Study Using the Information–Motivation–Behavioural Skills Model Journal of Clinical Medicine doi: 10.3390/jcm9103351 Authors: Jodie Scott Melissa Oxlad Jodie Dodd Claudia Szabo Andrea Deussen Deborah Turnbull Worldwide, half of women begin a pregnancy with overweight or obesity, which increases the risk of pregnancy and birth complications and...
Mon Oct 19, 2020 03:00
JCM, Vol. 9, Pages 3350: Predicting Perceived Stress Related to the Covid-19 Outbreak through Stable Psychological Traits and Machine Learning Models Journal of Clinical Medicine doi: 10.3390/jcm9103350 Authors: Luca Flesia Merylin Monaro Cristina Mazza Valentina Fietta Elena Colicino Barbara Segatto Paolo Roma The global SARS-CoV-2 outbreak and subsequent lockdown had a significant impact on people’s daily lives, with strong implications for stress levels...
Mon Oct 19, 2020 03:00
JoF, Vol. 6, Pages 234: Immunological Aspects of Chytridiomycosis Journal of Fungi doi: 10.3390/jof6040234 Authors: Grogan Humphries Robert Lanctôt Nock Newell McCallum Amphibians are currently the most threatened vertebrate class, with the disease chytridiomycosis being a major contributor to their global declines. Chytridiomycosis is a frequently fatal skin disease caused by the fungal pathogens Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans...
Mon Oct 19, 2020 03:00
JoF, Vol. 6, Pages 233: The Fungal Endophyte Serendipita williamsii Does Not Affect Phosphorus Status but Carbon and Nitrogen Dynamics in Arbuscular Mycorrhizal Tomato Plants Journal of Fungi doi: 10.3390/jof6040233 Authors: Hallasgo Spangl Steinkellner Hage-Ahmed Some members of the root endophytic Serendipitaceae were observed to frequently coexist with arbuscular mycorrhizal fungi (AMF), but their interactions and potential synergistic effects in plants have not yet been...
Mon Oct 19, 2020 03:00
JPM, Vol. 10, Pages 181: A Novel Nomenclature for Repeat Motifs in the Thymidylate Synthase Enhancer Region and Its Relevance for Pharmacogenetic Studies Journal of Personalized Medicine doi: 10.3390/jpm10040181 Authors: Dominic Schaerer Tanja K. Froehlich Seid Hamzic Steven M. Offer Robert B. Diasio Markus Joerger Ursula Amstutz Carlo R. Largiadèr Inhibition of thymidylate synthase (TS) is the primary mode of action for 5-fluorouracil (5FU) chemotherapy. TS expression...
Mon Oct 19, 2020 03:00
JPM, Vol. 10, Pages 180: Systems Biology and Experimental Model Systems of Cancer Journal of Personalized Medicine doi: 10.3390/jpm10040180 Authors: Yalcin Danisik Baygin Acar Over the past decade, we have witnessed an increasing number of large-scale studies that have provided multi-omics data by high-throughput sequencing approaches. This has particularly helped with identifying key (epi)genetic alterations in cancers. Importantly, aberrations that lead to the activation...
Mon Oct 19, 2020 03:00
JPM, Vol. 10, Pages 179: Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models Journal of Personalized Medicine doi: 10.3390/jpm10040179 Authors: Vincenzo Quagliariello Margherita Passariello Domenica Rea Antonio Barbieri Martina Iovine Annamaria Bonelli Antonietta Caronna Gerardo Botti Claudia De Lorenzo Nicola Maurea Background: Several strategies based on immune checkpoint inhibitors (ICIs) have been developed...
Mon Oct 19, 2020 03:00
Medicina, Vol. 56, Pages 549: Effect of Mucosal Brushing on the Serum Levels of C-Reactive Protein for Patients Hospitalized with Acute Symptoms Medicina doi: 10.3390/medicina56100549 Authors: Naoko Nakahodo Yoshiaki Nomura Takumi Oshiro Ryoko Otsuka Erika Kakuta Ayako Okada Yuko Inai Noriko Takei Nobuhiro Hanada This study was based in a hospital setting. Patients with acute symptoms face a life-threatening crisis and often have systemic complications during...
Mon Oct 19, 2020 03:00
Medicina, Vol. 56, Pages 548: Clinical Impact of Small Bowel Capsule Endoscopy in Obscure Gastrointestinal Bleeding Medicina doi: 10.3390/medicina56100548 Authors: Ana-Maria Singeap Camelia Cojocariu Irina Girleanu Laura Huiban Catalin Sfarti Tudor Cuciureanu Stefan Chiriac Carol Stanciu Anca Trifan Background and objectives: The most frequent indications for small bowel capsule endoscopy (SBCE) are obscure gastrointestinal bleeding (OGIB) and iron deficiency...
Mon Oct 19, 2020 03:00
Medicina, Vol. 56, Pages 547: Slow-Freezing Cryopreservation Ensures High Ovarian Tissue Quality Followed by In Vivo and In Vitro Methods and Is Safe for Fertility Preservation Medicina doi: 10.3390/medicina56100547 Authors: Živilė Gudlevičienė Kastytis Žilinskas Gabrielis Kundrotas Monika Grubliauskaitė Daiva Baltriukienė Virginija Bukelskienė Background and objectives: Cancer incidence is growing with younger patients diagnosed with this disease every year. Improved...
Mon Oct 19, 2020 03:00
Membranes, Vol. 10, Pages 294: Study of the Interaction of a Novel Semi-Synthetic Peptide with Model Lipid Membranes Membranes doi: 10.3390/membranes10100294 Authors: Lucia Sessa Simona Concilio Peter Walde Tom Robinson Petra S. Dittrich Amalia Porta Barbara Panunzi Ugo Caruso Stefano Piotto Most linear peptides directly interact with membranes, but the mechanisms of interaction are far from being completely understood. Here, we present an investigation of the...
Mon Oct 19, 2020 03:00
Metabolites, Vol. 10, Pages 419: Emerging Role of Metabolomics in Ovarian Cancer Diagnosis Metabolites doi: 10.3390/metabo10100419 Authors: Asia Saorin Emanuela Di Gregorio Gianmaria Miolo Agostino Steffan Giuseppe Corona Ovarian cancer is considered a silent killer due to the lack of clear symptoms and efficient diagnostic tools that often lead to late diagnoses. Over recent years, the impelling need for proficient biomarkers has led researchers to consider metabolomics,...
Mon Oct 19, 2020 03:00
Metabolites, Vol. 10, Pages 418: Metabolite Transporters as Regulators of Immunity Metabolites doi: 10.3390/metabo10100418 Authors: Hauke J. Weiss Stefano Angiari In the past decade, the rise of immunometabolism has fundamentally reshaped the face of immunology. As the functions and properties of many (immuno)metabolites have now been well described, their exchange among cells and their environment have only recently sparked the interest of immunologists. While many metabolites bind...
Mon Oct 19, 2020 03:00
Metabolites, Vol. 10, Pages 420: Relationships between Follicle-Stimulating Hormone and Adiponectin in Postmenopausal Women Metabolites doi: 10.3390/metabo10100420 Authors: Wan-Yu Huang Dar-Ren Chen Chew-Teng Kor Ting-Yu Chen Po-Te Lin Joseph Ta Chien Tseng Hung-Ming Wu Beyond fertility, follicle-stimulating hormone (FSH) may exert action on adipocytes, which are the major source of adiponectin and leptin, linking to insulin resistance. Therefore, we evaluated the relationships...
Mon Oct 19, 2020 03:00
Microorganisms, Vol. 8, Pages 1607: Effects of Different Stress Parameters on Growth and on Oleuropein-Degrading Abilities of Lactiplantibacillus plantarum Strains Selected as Tailored Starter Cultures for Naturally Table Olives Microorganisms doi: 10.3390/microorganisms8101607 Authors: Amanda Vaccalluzzo Alessandra Pino Maria De Angelis Joaquín Bautista-Gallego Flora Valeria Romeo Paola Foti Cinzia Caggia Cinzia L Randazzo The use of β-glucosidase positive...
Mon Oct 19, 2020 03:00
Microorganisms, Vol. 8, Pages 1608: An Alcohol Dehydrogenase 3 (ADH3) From Entamoeba histolytica is Involved in the Detoxification of Toxic Aldehydes Microorganisms doi: 10.3390/microorganisms8101608 Authors: Constantin König Martin Meyer Corinna Lender Sarah Nehls Tina Wallaschkowski Tobias Holm Thorben Matthies Dirk Lercher Jenny Matthiesen Helena Fehling Thomas Roeder Sophia Reindl Maria Rosenthal Nahla Galal Metwally Hannelore Lotter Iris Bruchhaus...
Mon Oct 19, 2020 03:00
Microorganisms, Vol. 8, Pages 1606: Electrically Charged Disinfectant Containing Calcium Hydrogen Carbonate Mesoscopic Crystals as a Potential Measure to Control Xanthomonas campestris pv. campestris on Cabbage Seeds Microorganisms doi: 10.3390/microorganisms8101606 Authors: Akikazu Sakudo Makoto Haritani Koichi Furusaki Rumiko Onishi Takashi Onodera Xanthomonas campestris pv. campestris (Xcc) is an important seed-borne bacterial pathogen that causes black rot in brassica....
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4811: Periselectivity in the Aza-Diels–Alder Reaction of 1-Azadienes with α-Oxoketenes: A Combined Experimental and Theoretical Study Molecules doi: 10.3390/molecules25204811 Authors: Marc Presset Michel Rajzmann Guillaume Dauvergne Jean Rodriguez Yoann Coquerel Inversions in the periselectivity of formal aza-Diels–Alder cycloadditions between α-oxoketenes generated by a thermally-induced Wolff rearrangement and 1-azadienes were...
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Molecules, Vol. 25, Pages 4810: Regulatory Impact of the C-Terminal Tail on Charge Transfer Pathways in Drosophila Cryptochrome Molecules doi: 10.3390/molecules25204810 Authors: Martin Richter Benjamin P. Fingerhut Interconnected transcriptional and translational feedback loops are at the core of the molecular mechanism of the circadian clock. Such feedback loops are synchronized to external light entrainment by the blue light photoreceptor cryptochrome (CRY) that undergoes conformational...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4809: Study of the Relationship between Leaf Color Formation and Anthocyanin Metabolism among Different Purple Pakchoi Lines Molecules doi: 10.3390/molecules25204809 Authors: Bo Song Hai Xu Longzheng Chen Xiaoxue Fan Zange Jing Song Chen Zhigang Xu Purple pakchoi (Brassica rapa ssp. Chinensis) is particularly appreciated due to its high edible quality and ornamental value, but there are few studies on the underlying mechanisms of leaf color...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4807: Lanostane Triterpenoids from the Fruiting Bodies of Fomes officinalis and Their Anti-Inflammatory Activities Molecules doi: 10.3390/molecules25204807 Authors: Jianxin Han Wei Liu Miaomiao Li Yanpei Gu Ying Zhang Tao Yuan In the current study, further chemical investigation of the fruiting bodies of Fomes officinalis led to isolate seven new 24-methyl-lanostane triterpenoids, named officimalonic acids I−O (1-7). Their structures...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4806: Computational Design of Nitrile Hydratase from Pseudonocardia thermophila JCM3095 for Improved Thermostability Molecules doi: 10.3390/molecules25204806 Authors: Zhongyi Cheng Yao Lan Junling Guo Dong Ma Shijin Jiang Qianpeng Lai Zhemin Zhou Lukasz Peplowski High thermostability and catalytic activity are key properties for nitrile hydratase (NHase, EC 4.2.1.84) as a well-industrialized catalyst. In this study, rational design was applied...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4808: Chemical Defense Mechanisms and Ecological Implications of Indo-Pacific Holothurians Molecules doi: 10.3390/molecules25204808 Authors: Elham Kamyab Sven Rohde Matthias Y. Kellermann Peter J. Schupp Sea cucumbers are slow-moving organisms that use morphological, but also a diversecombination of chemical defenses to improve their overall fitness and chances of survival. Sincechemical defense compounds are also of great pharmaceutical interest, we...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4804: Target-Guided Isolation of O-tigloylcyclovirobuxeine -B from Buxus sempervirens L. by Centrifugal Partition Chromatography Molecules doi: 10.3390/molecules25204804 Authors: Lara U. Szabó Thomas J. Schmidt The increasing drug resistance of malaria parasites challenges the treatment of this life-threatening disease. Consequently, the development of innovative and effective antimalarial drugs is inevitable. O-tigloylcyclovirobuxeine-B, a nor-cycloartane...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4803: α-Tocomonoenol Is Bioavailable in Mice and May Partly Be Regulated by the Function of the Hepatic α‑Tocopherol Transfer Protein Molecules doi: 10.3390/molecules25204803 Authors: Andrea Irías-Mata Nadine Sus Maria-Lena Hug Marco Müller Walter Vetter Jan Frank Tocomonoenols are vitamin E derivatives present in foods with a single double bond at carbon 11’ in the sidechain. The α-tocopherol transfer protein (TTP) is required...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4802: Tooth-Supporting Hard Tissue Regeneration Using Biopolymeric Material Fabrication Strategies Molecules doi: 10.3390/molecules25204802 Authors: Min Guk Kim Chan Ho Park The mineralized tissues (alveolar bone and cementum) are the major components of periodontal tissues and play a critical role to anchor periodontal ligament (PDL) to tooth-root surfaces. The integrated multiple tissues could generate biological or physiological responses to transmitted...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4805: Protein-Stabilized Palm-Oil-in-Water Emulsification Using Microchannel Array Devices under Controlled Temperature Molecules doi: 10.3390/molecules25204805 Authors: Takashi Kuroiwa Miki Ito Yaeko Okuyama Kanna Yamashita Akihiko Kanazawa Microchannel (MC) emulsification for the preparation of monodisperse oil-in-water (O/W) and water-in-oil-in-water (W/O/W) emulsions containing palm oil as the oil phase was investigated for application as basic...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4800: Antioxidant and Cell Proliferation Properties of the Vietnamese Traditional Medicinal Plant Peltophorum pterocarpum Molecules doi: 10.3390/molecules25204800 Authors: Seon-Rye Kim Dao Cuong Cuong To Phi Hung Nguyen Yen Nhi Nguyen Byung-Jun Cho Manh Hung Tran Peltophorum pterocarpum is regarded as one of the most important medicinal plants in the traditional medicine system of Vietnam. However, scientific evidence for the antioxidant effects...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4799: Influence of PVA Molecular Weight and Concentration on Electrospinnability of Birch Bark Extract-Loaded Nanofibrous Scaffolds Intended for Enhanced Wound Healing Molecules doi: 10.3390/molecules25204799 Authors: Francis Kamau Mwiiri Rolf Daniels Triterpenes from the outer bark of birch (TE) are known for various pharmacological effects including enhanced wound healing. Apart from an already authorized oleogel, electrospun nanofiber mats containing these...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4801: Rational Design of Polyamine-Based Cryogels for Metal Ion Sorption Molecules doi: 10.3390/molecules25204801 Authors: Irina Malakhova Yuliya Privar Yuliya Parotkina Aleksandr Mironenko Marina Eliseikina Denis Balatskiy Alexey Golikov Svetlana Bratskaya Here we report the method of fabrication of supermacroporous monolith sorbents (cryogels) via covalent cross-linking of polyallylamine (PAA) with diglycidyl ether of 1,4-butandiol. Using...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4797: Chemistry and Biological Activity of Alkaloids from the Genus Lycoris (Amaryllidaceae) Molecules doi: 10.3390/molecules25204797 Authors: Cahlíková Breiterová Opletal Lycoris Herbert, family Amaryllidaceae, is a small genus of about 20 species that are native to the warm temperate woodlands of eastern Asia, as in China, Korea, Japan, Taiwan, and the Himalayas. For many years, species of Lycoris have been subjected to extensive phytochemical and...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4796: Anti-Inflammatory Property of the Essential Oil from Cinnamomum camphora (Linn.) Presl Leaves and the Evaluation of Its Underlying Mechanism by Using Metabolomics Analysis Molecules doi: 10.3390/molecules25204796 Authors: Jiali Chen Cailin Tang Yang Zhou Rongfei Zhang Shaoxia Ye Zhimin Zhao Ligen Lin Depo Yang Cinnamomum camphora (Linn.) Presl has been widely used in traditional Chinese medicine for a variety of purposes. Our previous...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4794: Deep Eutectic Solvent-Based Microextraction of Lead(II) Traces from Water and Aqueous Extracts before FAAS Measurements Molecules doi: 10.3390/molecules25204794 Authors: Mohamed A. Habila Najla AlMasoud Taghrid S. Alomar Zeid A. AlOthman Erkan Yilmaz Mustafa Soylak Microextraction procedures for the separation of Pb(II) from water and food samples extracts were developed. A deep eutectic solvent composed of α-benzoin oxime and...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4795: Bioinspired Green Synthesis of Chitosan and Zinc Oxide Nanoparticles with Strong Antibacterial Activity against Rice Pathogen Xanthomonas oryzae pv. oryzae Molecules doi: 10.3390/molecules25204795 Authors: Yasmine Abdallah Mengju Liu Solabomi Olaitan Ogunyemi Temoor Ahmed Hatem Fouad Amro Abdelazez Chenqi Yan Yong Yang Jianping Chen Bin Li Bacterial leaf blight caused by Xanthomonas oryzae pv. oryzae (Xoo) is one of the most...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4792: Classification of the Multiple Stages of Parkinson’s Disease by a Deep Convolution Neural Network Based on 99mTc-TRODAT-1 SPECT Images Molecules doi: 10.3390/molecules25204792 Authors: Shih-Yen Hsu Li-Ren Yeh Tai-Been Chen Wei-Chang Du Yung-Hui Huang Wen-Hung Twan Ming-Chia Lin Yun-Hsuan Hsu Yi-Chen Wu Huei-Yung Chen Single photon emission computed tomography (SPECT) has been employed to detect Parkinson’s disease (PD)....
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4791: Are Multicentre Bond Indices and Related Quantities Reliable Predictors of Excited-State Aromaticity? Molecules doi: 10.3390/molecules25204791 Authors: Ponec Cooper Karadakov Systematic scrutiny is carried out of the ability of multicentre bond indices and the NOEL-based similarity index dAB to serve as excited-state aromaticity criteria. These indices were calculated using state-optimized complete active-space self-consistent field wavefunctions...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4793: Rapid, Precise and Affordable Estimation of Venlafaxine and Its Metabolites in Highly Polluted Effluent Waters: Proof-of-Concept for Methodology Molecules doi: 10.3390/molecules25204793 Authors: Snawar Hussain Chandramouli Ramnarayanan Teeka S. Roopashree Md. Khalid Anwer Nagaraja Sreeharsha Anroop B. Nair Widespread presence of pharmaceuticals and their metabolites in the environment of industrialized countries is an emerging global concern....
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4789: Chemical Space Charting of Different Parts of Inula nervosa Wall.: Upregulation of Expression of Nrf2 and Correlated Antioxidants Enzymes Molecules doi: 10.3390/molecules25204789 Authors: Xiang-rong Cheng Wei Zhao Wen-le Dong Guo-wei Le The edible and medicinal part of Inula nervosa Wall. (Xiaoheiyao) is confined to its root without sufficient phytochemical and biological investigation. In this study, the secondary metabolites of root, stem, leaf,...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4788: The Combination of Selenium and LED Light Quality Affects Growth and Nutritional Properties of Broccoli Sprouts Molecules doi: 10.3390/molecules25204788 Authors: Rui He Meifang Gao Rui Shi Shiwei Song Yiting Zhang Wei Su Houcheng Liu Selenium (Se) supplement was combined with different LED light qualities to investigate mutual effects on the growth, nutritional quality, contents of glucosinolates and mineral elements in broccoli sprouts....
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4790: Mapping the Mechanical Properties of Hierarchical Supercrystalline Ceramic-Organic Nanocomposites Molecules doi: 10.3390/molecules25204790 Authors: Büsra Bor Lydia Heilmann Berta Domènech Michael Kampferbeck Tobias Vossmeyer Horst Weller Gerold A. Schneider Diletta Giuntini Multiscale ceramic-organic supercrystalline nanocomposites with two levels of hierarchy have been developed via self-assembly with tailored content of the organic...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4786: Structural Study on Fat Crystallization Process Heterogeneously Induced by Graphite Surfaces Molecules doi: 10.3390/molecules25204786 Authors: Fumitoshi Kaneko Yoshinori Yamamoto Shinichi Yoshikawa Some inorganic and organic crystals have been recently found to promote fat crystallization in thermodynamically stable polymorphs, though they lack long hydrocarbon chains. The novel promoters are talc, carbon nanotube, graphite, theobromine, ellagic...
Mon Oct 19, 2020 03:00
Molecules, Vol. 25, Pages 4787: Assessing the Direct Binding of Ark-Like E3 RING Ligases to Ubiquitin and Its Implication on Their Protein Interaction Network Molecules doi: 10.3390/molecules25204787 Authors: Dimitris G. Mintis Anastasia Chasapi Konstantinos Poulas George Lagoumintzis Christos T. Chasapis The ubiquitin pathway required for most proteins’ targeted degradation involves three classes of enzymes: E1-activating enzyme, E2-conjugating enzyme, and E3-ligases....
Mon Oct 19, 2020 03:00
Nanomaterials, Vol. 10, Pages 2066: Synthesis and Characterization of CuIn1−xGaxSe2 Semiconductor Nanocrystals Nanomaterials doi: 10.3390/nano10102066 Authors: Yu-Tai Shih Yu-Ching Tsai Der-Yu Lin In this paper, the synthesis and characterization of CuIn1−xGaxSe2 (0 £ x £ 1) nanocrystals are reported with the influences of x value on the structural, morphological, and optical properties of the nanocrystals. The X-ray diffraction (XRD) results showed...
Mon Oct 19, 2020 03:00
Nanomaterials, Vol. 10, Pages 2065: Are Titania Photocatalysts and Titanium Implants Safe? Review on the Toxicity of Titanium Compounds Nanomaterials doi: 10.3390/nano10102065 Authors: Markowska-Szczupak Endo-Kimura Paszkiewicz Kowalska Titanium and its compounds are broadly used in both industrial and domestic products, including jet engines, missiles, prostheses, implants, pigments, cosmetics, food, and photocatalysts for environmental purification and solar energy conversion....
Mon Oct 19, 2020 03:00
Nanomaterials, Vol. 10, Pages 2064: Recent Progress on the Gold-Free Integration of Ternary III–As Antimonide Nanowires Directly on Silicon Nanomaterials doi: 10.3390/nano10102064 Authors: Ezekiel Anyebe Anyebe During the last few years, there has been renewed interest in the monolithic integration of gold-free, Ternary III–As Antimonide (III–As–Sb) compound semiconductor materials on complementary metal-oxide-semiconductor (CMOS)—compatible silicon...
Mon Oct 19, 2020 03:00
Nanomaterials, Vol. 10, Pages 2063: Synergistic Effect of Graphene/Silver Nanowire Hybrid Fillers on Highly Stretchable Strain Sensors Based on Spandex Composites Nanomaterials doi: 10.3390/nano10102063 Authors: Vo Lee Kim Suk Embedding conductive nanomaterials into elastomeric polymer matrices is one of the most promising approaches for fabricating stretchable strain sensors capable of monitoring large mechanical movements or deformation through the detection of resistance...
Mon Oct 19, 2020 03:00
Nanomaterials, Vol. 10, Pages 2062: Eco-Friendly Supercapacitors Based on Biodegradable Poly(3-Hydroxy-Butyrate) and Ionic Liquids Nanomaterials doi: 10.3390/nano10102062 Authors: Lorenzo Migliorini Tommaso Santaniello Francesca Borghi Paolo Saettone Mauro Comes Franchini Gianluca Generali Paolo Milani The interest for biodegradable electronic devices is rapidly increasing for application in the field of wearable electronics, precision agriculture, biomedicine, and...
Mon Oct 19, 2020 03:00
Nanomaterials, Vol. 10, Pages 2061: Hexagonal and Monoclinic Phases of La2O2CO3 Nanoparticles and Their Phase-Related CO2 Behavior Nanomaterials doi: 10.3390/nano10102061 Authors: Hongyan Yu Kaiming Jiang Sung Gu Kang Yong Men Eun Woo Shin In this study, we prepared hexagonal and monoclinic phases of La2O2CO3 nanoparticles by different wet preparation methods and investigated their phase-related CO2 behavior through field-emission scanning microscopy, high-resolution transmission...
Mon Oct 19, 2020 03:00
Nanomaterials, Vol. 10, Pages 2060: Hybrid Magnetorheological Composites for Electric and Magnetic Field Sensors and Transducers Nanomaterials doi: 10.3390/nano10102060 Authors: Ioan Bica Eugen Mircea Anitas Liviu Chirigiu We present a simple, low-cost, and environmental-friendly method for the fabrication of hybrid magnetorheological composites (hMCs) based on cotton fibers soaked with a mixture of silicone oil (SO), carbonyl iron (CI) microparticles, and iron oxide microfibers...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3197: A High-Fat Diet Increases Gut Microbiota Biodiversity and Energy Expenditure Due to Nutrient Difference Nutrients doi: 10.3390/nu12103197 Authors: Botao Wang Qingmin Kong Xiu Li Jianxin Zhao Hao Zhang Wei Chen Gang Wang A high-fat diet (HFD) can easily induce obesity and change the gut microbiota and its metabolites. However, studies on the effects of high-fat diets on the host have drawn inconsistent results. In this study, the unexpected...
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Nutrients, Vol. 12, Pages 3196: Effect of Vitamin D Status during Pregnancy on Infant Neurodevelopment: The ECLIPSES Study Nutrients doi: 10.3390/nu12103196 Authors: Voltas Canals Hernández-Martínez Serrat Basora Arija Vitamin D status during pregnancy is involved in numerous physiological processes, including brain development. In this study, we assess the association between vitamin D status during pregnancy and infant neurodevelopment (cognitive, language, and...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3195: The Extract of Arctium lappa L. Fruit (Arctii Fructus) Improves Cancer-Induced Cachexia by Inhibiting Weight Loss of Skeletal Muscle and Adipose Tissue Nutrients doi: 10.3390/nu12103195 Authors: Han Mun Jeon Yoon Choi Kee Hong Background: Cachexia induced by cancer is a systemic wasting syndrome and it accompanies continuous body weight loss with the exhaustion of skeletal muscle and adipose tissue. Cancer cachexia is not only...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3193: Decreased Histone Acetylation Levels at Th1 and Regulatory Loci after Induction of Food Allergy Nutrients doi: 10.3390/nu12103193 Authors: Alashkar Alhamwe Meulenbroek Veening-Griffioen Wehkamp Alhamdan Miethe Harb Hogenkamp Knippels Pogge von Strandmann Renz Garssen van Esch Garn Potaczek Tiemessen Immunoglobulin E (IgE)-mediated allergy against cow’s milk protein fractions such as...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3190: Mapping Young Adults’ Concerns and Attitudes toward Food-Related Sustainability Issues in Israel: Implications for Food Policy Nutrients doi: 10.3390/nu12103190 Authors: Sigal Tepper Vered Kaufman-Shriqui Danit Rivka Shahar Identifying the concerns about and attitudes toward adopting a healthy, sustainable diet may facilitate the development of effective implementation policies targeted at changing an individual’s dietary choices toward...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3194: Assessing the Effects of Ginger Extract on Polyphenol Profiles and the Subsequent Impact on the Fecal Microbiota by Simulating Digestion and Fermentation In Vitro Nutrients doi: 10.3390/nu12103194 Authors: Jing Wang Yong Chen Xiaosong Hu Fengqin Feng Luyun Cai Fang Chen The beneficial effects of ginger polyphenols have been extensively reported. However, their metabolic characteristics and health effects on gut microbiota are poor understood....
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3191: Elderly Perception of Distance to the Grocery Store as a Reason for Feeling Food Insecurity—Can Food Policy Limit This? Nutrients doi: 10.3390/nu12103191 Authors: Robert Gajda Marzena Jeżewska-Zychowicz The sense of food insecurity in a group of elderly people may be determined by the perception of distance to food outlets. The aim of the study was to assess the relationship between the perception of food insecurity by the elderly and their perception...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3189: Vitamin D and Sarcopenia: Potential of Vitamin D Supplementation in Sarcopenia Prevention and Treatment Nutrients doi: 10.3390/nu12103189 Authors: Ran Uchitomi Mamoru Oyabu Yasutomi Kamei Skeletal muscle, the largest organ in the human body, accounting for approximately 40% of body weight, plays important roles in exercise and energy expenditure. In the elderly, there is often a progressive decline in skeletal muscle mass and function, a condition...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3192: Intravenous Glutamine Administration Improves Glucose Tolerance and Attenuates the Inflammatory Response in Diet-Induced Obese Mice after Sleeve Gastrectomy Nutrients doi: 10.3390/nu12103192 Authors: Yeh Yang Lee Wu Chen Huang Yeh Lin Obesity is a health problem associated with many metabolic disorders. Weight reduction can effectively alleviate obesity-associated complications. Sleeve gastrectomy is a commonly used bariatric...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3187: Association between Serum Zinc Levels and Clinical Index or the Body Composition in Incident Hemodialysis Patients Nutrients doi: 10.3390/nu12103187 Authors: Tatsunori Toida Reiko Toida Shou Ebihara Risa Takahashi Hiroyuki Komatsu Shigehiro Uezono Yuji Sato Shouichi Fujimoto Background: The relationships between serum zinc levels and body composition or clinical outcomes of incident hemodialysis (HD) patients remain unclear. Methods:...
Mon Oct 19, 2020 03:00
Nutrients, Vol. 12, Pages 3188: Use of Metabolomic Profiling to Understand Variability in Adiposity Changes Following an Intentional Weight Loss Intervention in Older Adults Nutrients doi: 10.3390/nu12103188 Authors: Ellen E. Quillen Daniel P. Beavers Anderson O’Brien Cox Cristina M. Furdui Jingyun Lee Ryan M. Miller Hanzhi Wu Kristen M. Beavers Inter-individual response to dietary interventions remains a major challenge to successful weight loss among older adults....
Mon Oct 19, 2020 03:00
Pathogens, Vol. 9, Pages 853: An Abattoir-Based Study on the Prevalence of Salmonella Fecal Carriage and ESBL Related Antimicrobial Resistance from Culled Adult Dairy Cows in Wuhan, China Pathogens doi: 10.3390/pathogens9100853 Authors: Jie Wang Kaili Xue Ping Yi Xiaojie Zhu Qingjie Peng Zijian Wang Yongchong Peng Yingyu Chen Ian D. Robertson Xiang Li Aizhen Guo Joshua W. Aleri The objective of this study was to estimate the fecal carriage of Salmonella...
Mon Oct 19, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 320: Impact of Washingtonia robusta Leaves on Gamma Irradiation-Induced Hepatotoxicity in Rats and Correlation with STING Pathway and Phenolic Composition Pharmaceuticals doi: 10.3390/ph13100320 Authors: Nabil M. Selim Seham S. El-Hawary Soheir M. El Zalabani Rehab Nabil Shamma Nariman El Sayed Mahdy Noheir H. Sherif Hanan A. Fahmy Mai H. Mekkawy Abdelaziz Yasri Mansour Sobeh Exposure to ionizing radiation usually results in...
Mon Oct 19, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 319: Exosomes in Gliomas: Biogenesis, Isolation, and Preliminary Applications in Nanomedicine Pharmaceuticals doi: 10.3390/ph13100319 Authors: Eugenia Romano Paolo Antonio Netti Enza Torino Exosomes are phospholipid-based particles endogenously produced by both normal and tumor cells. Initially identified as a pathway for shuttling cellular waste, for a long time they were thought to act as “garbage bags”, and only in the past...
Mon Oct 19, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 318: Attenuation of Spatial Memory in 5xFAD Mice by Halting Cholinesterases, Oxidative Stress and Neuroinflammation Using a Cyclopentanone Derivative Pharmaceuticals doi: 10.3390/ph13100318 Authors: Rahim Ullah Gowhar Ali Nisar Ahmad Muhammad Akram Geeta Kumari Muhammad Usman Amin Muhammad Naveed Umar Alzheimer’s disease (AD) is an irreversible and chronic neurological disorder that gradually destroys memory and thinking skills....
Mon Oct 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 989: Evaluation of CpG-ODN-Adjuvanted Toxoplasma Gondii Virus-Like Particle Vaccine upon One, Two, and Three Immunizations Pharmaceutics doi: 10.3390/pharmaceutics12100989 Authors: Kang Chu Kim Park Jin Lee Moon Quan Successful vaccines against specific pathogens often require multiple immunizations and adjuvant usage. Yet, assessing the protective efficacy of different immunization regimens with adjuvanted Toxoplasma gondii...
Mon Oct 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 990: Adjuvant Antitumor Immunity Contributes to the Overall Antitumor Effect of Pegylated Liposomal Doxorubicin (Doxil®) in C26 Tumor-Bearing Immunocompetent Mice Pharmaceutics doi: 10.3390/pharmaceutics12100990 Authors: Takayama Shimizu Lila Kanazawa Ando Ishima Ishida Doxorubicin (DXR) has been reported to have direct cytotoxicity against cancer cells and indirect immunotoxicity by modulation of host antitumor immunity. Hence,...
Mon Oct 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 988: Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs Pharmaceutics doi: 10.3390/pharmaceutics12100988 Authors: de Souza Teixeira Vila Chagas Alonso Gonzalez-Alvarez Bermejo Polli Rezende A major parameter controlling the extent and rate of oral drug absorption is permeability through the lipid bilayer of intestinal epithelial cells. Here, a biomimetic artificial membrane permeability...
Mon Oct 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 991: Erratum: Mwiiri, F.K.; et al. Electrospun Bioactive Wound Dressing Containing Colloidal Dispersions of Birch Bark Dry Extract. Pharmaceutics 2020, 12, 770 Pharmaceutics doi: 10.3390/pharmaceutics12100991 Authors: Mwiiri Brandner Daniels The authors wish to make the following correction to this paper [...]
Mon Oct 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 987: Anti-Cancer Activity of As4O6 and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer Pharmaceutics doi: 10.3390/pharmaceutics12100987 Authors: Joseph J. Noh Myeong-Seon Kim Young-Jae Cho Soo-Young Jeong Yoo-Young Lee Ji-Yoon Ryu Jung-Joo Choi Illju Bae Zhaoyan Wu Byoung-Gie Kim Jae Ryoung Hwang Jeong-Won Lee Purpose: To investigate the anti-cancer effects of tetraarsenic hexoxide (TAO, As4O6)...
Mon Oct 19, 2020 03:00
Pharmaceutics, Vol. 12, Pages 986: Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer Pharmaceutics doi: 10.3390/pharmaceutics12100986 Authors: Francisco J. Cimas Enrique Niza Alberto Juan María del Mar Noblejas-López Iván Bravo Agustín Lara-Sanchez Carlos Alonso-Moreno Alberto Ocaña Bromo and extraterminal domain (BET) inhibitors-PROteolysis TArgeting Chimera (BETi-PROTAC) is a new family...
Mon Oct 19, 2020 03:00
Pharmacy, Vol. 8, Pages 193: A New Case Manager for Diabetic Patients: A Pilot Observational Study of the Role of Community Pharmacists and Pharmacy Services in the Case Management of Diabetic Patients Pharmacy doi: 10.3390/pharmacy8040193 Authors: La Regina Pandolfi Stabile Beloni Glisenti Griggio La Regina La Regina The adherence of type 2 diabetes mellitus (DM2) patients with an individual care plan (ICP) is often not satisfactory, nor does it allow for...
Mon Oct 19, 2020 03:00
Plants, Vol. 9, Pages 1390: Prediction of Dhurrin Metabolism by Transcriptome and Metabolome Analyses in Sorghum Plants doi: 10.3390/plants9101390 Authors: Choi Chung Lee Kang Park Park Kim Sorghum (Sorghum bicolor (L.)) Moench is an important food for humans and feed for livestock. Sorghum contains dhurrin which can be degraded into toxic hydrogen cyanide. Here, we report the expression patterns of 14 candidate genes related to dhurrin ((S)-4-Hydroxymandelnitrile-β-D-glucopyranoside)...
Mon Oct 19, 2020 03:00
Plants, Vol. 9, Pages 1389: Phosphorus Nutrient Management through Synchronization of Application Methods and Rates in Wheat and Maize Crops Plants doi: 10.3390/plants9101389 Authors: Rafiullah Khan Muhammad Fahad Adnan Wahid Alamri Khan Dawar Irshad Danish Arif Amanullah Saud Khan Mian Datta Zarei Shah Ramzan Zafar-ul-Hye Mussarat Siddiqui Management of inorganic fertilizer is very important to...
Mon Oct 19, 2020 03:00
Plants, Vol. 9, Pages 1388: Overexpression of CDSP32 (GhTRX134) Cotton Gene Enhances Drought, Salt, and Oxidative Stress Tolerance in Arabidopsis Plants doi: 10.3390/plants9101388 Authors: Mohammed Elasad Adeel Ahmad Hantao Wang Liang Ma Shuxun Yu Hengling Wei Upland cotton (Gossypium hirsutum L.) is the main natural fiber crop worldwide and is an essential source of seed oil and biofuel products. Many abiotic stresses, such as drought and salinity, constrain cotton production....
Mon Oct 19, 2020 03:00
Recycling, Vol. 5, Pages 28: Organic Material for Clean Production in the Batik Industry: A Case Study of Natural Batik Semarang, Indonesia Recycling doi: 10.3390/recycling5040028 Authors: Nana Kariada Tri Martuti Isti Hidayah Margunani Margunani Radhitya Bayu Alafima Batik has become more desirable in the current fashion mode within the global market, but the environmental damage induced by this fabric’s synthetic dye practices is a matter of concern. This study aimed...
Mon Oct 19, 2020 03:00
Recycling, Vol. 5, Pages 27: Pros and Cons of Plastic during the COVID-19 Pandemic Recycling doi: 10.3390/recycling5040027 Authors: Fabiula Danielli Bastos de Sousa Since the beginning of the first cases of the new coronavirus, opinions and laws on the use of plastic materials have been questioned around the world. Their importance in the manufacture of hospital devices and personal protective equipment (PPE) is unquestionable, as they contribute largely to the reduction of the virus...
Mon Oct 19, 2020 03:00
Religions, Vol. 11, Pages 534: Policy on Religion in the European Union Religions doi: 10.3390/rel11100534 Authors: Piotr Mazurkiewicz The main idea of article is that, even if EU has no competence in religious matters, what we can observe now is a creation of a very specific policy on religion. (1) Herein, I explain why the EU is interested in religion and how it is improving its competence with respect to it. Mostly, this is achieved by a transformation of religious matters into secular...
Mon Oct 19, 2020 03:00
Religions, Vol. 11, Pages 533: Rhizomatic Religion and Material Destruction in Kham Tibet: The Case of Yachen Gar Religions doi: 10.3390/rel11100533 Authors: Daan F. Oostveen This article looks at the Tibetan Buddhism revitalization in China in particular, in Kham Tibet, and the way how it was both made possible and obstructed by the Chinese state. As a case, we look at the Yachen Gar monastery in the West of Sichuan. The Yachen Gar monastery became the largest Buddhist university in...
Mon Oct 19, 2020 03:00
Religions, Vol. 11, Pages 532: Music and Spirituality: A Journey into Porosity Religions doi: 10.3390/rel11100532 Authors: Edward Foley Early in my studies a treasured mentor once interrupted a presentation I was giving in his doctoral seminar when I too blithely attempted to distinguish “authentic” liturgy from people’s popular devotions [...]
Mon Oct 19, 2020 03:00
Risks, Vol. 8, Pages 108: Comparing Two Different Option Pricing Methods Risks doi: 10.3390/risks8040108 Authors: Alessandro Bondi Dragana Radojičić Thorsten Rheinländer Motivated by new financial markets where there is no canonical choice of a risk-neutral measure, we compared two different methods for pricing options: calibration with an entropic penalty term and valuation by the Esscher measure. The main aim of this paper is to contrast the outcomes of those two methods with...
Mon Oct 19, 2020 03:00
Robotics, Vol. 9, Pages 87: Finite-Time State Estimation for an Inverted Pendulum under Input-Multiplicative Uncertainty Robotics doi: 10.3390/robotics9040087 Authors: Anu Kossery Jayaprakash Krishna Bhavithavya Kidambi William MacKunis Sergey V. Drakunov Mahmut Reyhanoglu A sliding mode observer is presented, which is rigorously proven to achieve finite-time state estimation of a dual-parallel underactuated (i.e., single-input multi-output) cart inverted pendulum system...
Mon Oct 19, 2020 03:00
Safety, Vol. 6, Pages 47: A Cloud-Based Tool for Integrating Occupational Risk Assessment Within Management Systems for SMEs Safety doi: 10.3390/safety6040047 Authors: De Merich Gnoni Malorgio Micheli Piga Sala Tornese About 67% of workers employed in the industrial and service sectors in the European Union are currently contracted by Small- and Medium-sized Enterprises (SMEs), which represent the economic heart of the European economy. However, this strength...
Mon Oct 19, 2020 03:00
Smart Cities, Vol. 3, Pages 1219-1241: A Testbed for GNSS-Based Positioning and Navigation Technologies in Smart Cities: The HANSEL Project Smart Cities doi: 10.3390/smartcities3040060 Authors: Alex Minetto Fabio Dovis Andrea Vesco Miquel Garcia-Fernandez Àlex López-Cruces José Luis Trigo Marc Molina Alejandro Pérez-Conesa Joaquín Gáñez-Fernández Gonzalo Seco-Granados José A. López-Salcedo In urban contexts, the increasing density of electronic devices equipped...
Mon Oct 19, 2020 03:00
Stats, Vol. 3, Pages 444-464: Local Processing of Massive Databases with R: A National Analysis of a Brazilian Social Programme Stats doi: 10.3390/stats3040028 Authors: Hellen Paz Mateus Maia Fernando Moraes Ricardo Lustosa Lilia Costa Samuel Macêdo Marcos E. Barreto Anderson Ara The analysis of massive databases is a key issue for most applications today and the use of parallel computing techniques is one of the suitable approaches for that. Apache Spark is a widely...
Mon Oct 19, 2020 03:00
Toxins, Vol. 12, Pages 662: Clinical Features and Management of Snakebite Envenoming in French Guiana Toxins doi: 10.3390/toxins12100662 Authors: Dabor Resiere Stéphanie Houcke Jean Marc Pujo Claire Mayence Cyrille Mathien Flaubert NkontCho Nicaise Blaise Magalie Pierre Demar Didier Hommel Hatem Kallel The management of snakebite (SB) envenoming in French Guiana (FG) is based on symptomatic measures and antivenom (AV) administration (Antivipmyn Tri®;...
Mon Oct 19, 2020 03:00
Toxins, Vol. 12, Pages 661: Safety and Stability of Pulmonary Function in Patients with Decreased Respiratory Function Treated for Spasticity with OnabotulinumtoxinA Toxins doi: 10.3390/toxins12100661 Authors: Ziyad Ayyoub Allison Brashear Marta Banach Robert Schoene William Stringer Terry Boodhoo Irina Yushmanova Rozalina Dimitrova Mitchell F. Brin Two randomized, placebo-controlled studies evaluated the pulmonary function safety of onabotulinumtoxinA (onabotA)...
Mon Oct 19, 2020 03:00
Vaccines, Vol. 8, Pages 617: IFN-Alpha-Mediated Differentiation of Dendritic Cells for Cancer Immunotherapy: Advances and Perspectives Vaccines doi: 10.3390/vaccines8040617 Authors: Caterina Lapenta Lucia Gabriele Stefano Maria Santini The past decade has seen tremendous developments in novel cancer therapies through targeting immune-checkpoint molecules. However, since increasing the presentation of tumor antigens remains one of the major issues for eliciting a strong antitumor...
Mon Oct 19, 2020 03:00
Viruses, Vol. 12, Pages 1183: A Nationwide Study about the Dispersal Patterns of the Predominant HIV-1 Subtypes A1 and B in Greece: Inference of the Molecular Transmission Clusters Viruses doi: 10.3390/v12101183 Authors: Evangelia Georgia Kostaki Maria Gova Georgios Adamis Georgios Xylomenos Maria Chini Nikos Mangafas Marios Lazanas Simeon Metallidis Olga Tsachouridou Vasileios Papastamopoulos Dimitrios Chatzidimitriou Eleni Kakalou Anastasia Antoniadou...
Mon Oct 19, 2020 03:00
Viruses, Vol. 12, Pages 1181: Special Issue: Bovine Viral Diarrhea Virus and Related Pestiviruses Viruses doi: 10.3390/v12101181 Authors: Bielefeldt-Ohmann The genus Pestivirus, encompassing small positive-strand RNA viruses in the family Flaviviridae, comprises four viruses of very significant economic impact to the cattle, swine and sheep industries worldwide: bovine viral diarrhoea virus (BVDV) type 1 and type 2, classical swine fever virus (CSFV) and border disease virus (BDV)....
Mon Oct 19, 2020 03:00
Viruses, Vol. 12, Pages 1180: Metatranscriptomic Identification of Diverse and Divergent RNA Viruses in Green and Chlorarachniophyte Algae Cultures Viruses doi: 10.3390/v12101180 Authors: Justine Charon Vanessa Rossetto Marcelino Richard Wetherbee Heroen Verbruggen Edward C. Holmes Our knowledge of the diversity and evolution of the virosphere will likely increase dramatically with the study of microbial eukaryotes, including the microalgae within which few RNA viruses have...
Mon Oct 19, 2020 03:00
Viruses, Vol. 12, Pages 1182: Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs Viruses doi: 10.3390/v12101182 Authors: Punga Darweesh Akusjärvi Human adenoviruses (HAdVs) are common pathogens causing a variety of respiratory, ocular and gastrointestinal diseases. To accomplish their efficient replication, HAdVs take an advantage of viral small non-coding RNAs (sncRNAs), which have multiple roles during the virus lifecycle. Three of the best-characterized...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2925: Improving Regulation and the Role of Natural Risk Knowledge to Promote Sustainable Low Enthalpy Geothermal Energy Utilization Water doi: 10.3390/w12102925 Authors: Giorgio De Giorgio Michele Chieco Pier Paolo Limoni Livia Emanuela Zuffianò Vittoria Dragone Annarita Romanazzi Rossella Pagliarulo Giuseppe Musicco Maurizio Polemio The use of geothermal energy resources to support anthropogenic activities have a long-lasting tradition,...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2923: Application of the Systems Approach to the Management of Complex Water Systems Water doi: 10.3390/w12102923 Authors: Slobodan P. Simonovic This paper provides an introduction to, and an overview of, the Special Issue on the application of systems approach to the management of complex water systems. The main motivation in proposing this Special Issue was that today, more than ever, we need a systems approach to assist in dealing with the difficulties introduced...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2922: Influence of Unsteady Flow Induced by a Large-Scale Hydropower Station on the Water Level Fluctuation of Multi-Approach Channels: A Case Study of the Three Gorges Project, China Water doi: 10.3390/w12102922 Authors: Zhiyong Wan Yun Li Xiaogang Wang Jianfeng An Bo Dong Yipeng Liao Unsteady flow induced by hydropower stations exerts a significant impact on the water level in multi-approach channels, which directly threatens the safe passage of...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2924: Spatio-Temporal Dynamics of Riverine Nitrogen and Phosphorus at Different Catchment Scales in Huixian Karst Wetland, Southwest China Water doi: 10.3390/w12102924 Authors: Linyan Pan Junfeng Dai Zhiqiang Wu Zupeng Wan Zhenyu Zhang Junlei Han Zhangnan Li Xiaolin Xie Baoli Xu Spatio-temporal dynamics of riverine nitrogen (N) and phosphorus (P) in karst regions are closely linked to hydrological conditions, human activities and karst features...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2918: Stable-Isotope-Aided Investigation of the Effect of Redox Potential on Nitrous Oxide Emissions as Affected by Water Status and N Fertilization Water doi: 10.3390/w12102918 Authors: Jihuan Wang Heye R. Bogena Harry Vereecken Nicolas Brüggemann Soils are the dominant source of atmospheric nitrous oxide (N2O), especially agricultural soils that experience both waterlogging and intensive nitrogen fertilization. However, soil heterogeneity and the irregular...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2920: Long-Term Temporal Changes of Precipitation Quality in Slovak Mountain Forests Water doi: 10.3390/w12102920 Authors: Jozef Minďaš Miriam Hanzelová Jana Škvareninová Jaroslav Škvarenina Ján Ďurský Slávka Tóthová The paper is focused on the evaluation of long-term changes in the chemical composition of precipitation in the mountain forests of Slovakia. Two stations with long-term measurements of precipitation quality were selected, namely the...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2916: Modelling of the Complex Groundwater Level Dynamics during Episodic Rainfall Events of a Surficial Aquifer in Southern Italy Water doi: 10.3390/w12102916 Authors: Nicola Pastore Claudia Cherubini Angelo Doglioni Concetta Immacolata Giasi Vincenzo Simeone We analyzed the complex dynamics that are involved the groundwater level variations due to the episodic rainfall supply in the Ionian coastal plain surficial aquifer located in Southern Italy....
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2919: An Empirical Orthogonal Function-Based Approach for Spatially- and Temporally-Extensive Soil Moisture Data Combination Water doi: 10.3390/w12102919 Authors: Zhao Li Yao Jiao Hill Modeling and prediction of soil hydrologic processes require identifying soil moisture spatial-temporal patterns and effective methods allowing the data observations to be used across different spatial and temporal scales. This work presents a methodology for combining...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2917: Carbon Balance and Streamflow at a Small Catchment Scale 10 Years after the Severe Natural Disturbance in the Tatra Mts, Slovakia Water doi: 10.3390/w12102917 Authors: Peter Fleischer Ladislav Holko Slavomír Celer Lucia Čekovská Jozef Rozkošný Peter Škoda Lukáš Olejár Peter Fleischer Natural disturbances (windthrow, bark beetle, and fire) have reduced forest cover in the Tatra National Park (Slovakia) by 50% since the year 2004. We analyzed...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2921: An Overview and Evaluation of Highly Porous Adsorbent Materials for Polycyclic Aromatic Hydrocarbons and Phenols Removal from Wastewater Water doi: 10.3390/w12102921 Authors: Zakariyya Uba Zango Nonni Soraya Sambudi Khairulazhar Jumbri Anita Ramli Noor Hana Hanif Abu Bakar Bahruddin Saad Muhammad Nur’ Hafiz Rozaini Hamza Ahmad Isiyaka Abubaker Mohammed Osman Abdelmoneim Sulieman Abstract Polycyclic aromatic hydrocarbons (PAHs) and...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2915: Water Balance Assessment in Schools and Households of Rural Areas of Coquimbo Region, North-Central Chile: Potential for Greywater Reuse Water doi: 10.3390/w12102915 Authors: Carolina Rodríguez Rafael Sánchez Javier Lozano-Parra Natalia Rebolledo Nicolás Schneider Jennyfer Serrano Eduardo Leiva Population growth, global warming, and increased demand for water have caused global concern about increasing water scarcity. Chile has an unequal...
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2914: Correction: Jang, D., et al. The Downscaling Study for Typhoon-Induced Coastal Inundation. Water 2020, 12, 1103 Water doi: 10.3390/w12102914 Authors: Dongmin Jang Wonkyun Joo Chang-Hoo Jeong Wonsu Kim Sung Won Park Yoojin Song The authors wish to make the following corrections to this paper [...]
Mon Oct 19, 2020 03:00
Water, Vol. 12, Pages 2913: A New Tool for Assessing Environmental Impacts of Altering Short-Term Flow and Water Level Regimes Water doi: 10.3390/w12102913 Authors: María Dolores Bejarano Jaime H. García-Palacios Alvaro Sordo-Ward Luis Garrote Christer Nilsson The computational tool InSTHAn (indicators of short-term hydrological alteration) was developed to summarize data on subdaily stream flows or water levels into manageable, comprehensive and ecologically meaningful metrics,...
Mon Oct 19, 2020 03:00
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