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Τετάρτη 7 Φεβρουαρίου 2018

Outcomes for dermatology inpatients treated with a simplified short-contact wet wrap protocol



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Outcomes of the use of Ligamentotaxor® for proximal interphalangeal fractures of the hand: North Bristol hand centre experience



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Development of a new adsorbent from pumpkin husk by KOH-modification to remove copper ions

Abstract

Heavy metal pollution in watercourses is a major environmental problem throughout the world due to rapid population growth, industrialization, and economic development. Considering this, the present study aimed to develop a new adsorbent from pumpkin husk (PH) by KOH modification to remove copper (Cu2+) ions and to explore its adsorptive potential. The sorption studies of Cu2+ on KOH-modified PH were carried out as functions of particle size, solution pH, adsorbent dose, temperature, initial metal concentration, and contact time. The sorption capacity of KOH-modified PH was found to be higher than that of raw PH, as 19.4 and 10.2 mg g−1, respectively. Morphology and surface structures of adsorbents were characterized by determination of zero point charge, a Fourier transform infrared spectrometer (FTIR–ATR) spectra, and a scanning electron microscopy (SEM) of PH powders before and after the sorption of Cu2+. The pHzpc of PH was found to be 5.0. FTIR–ATR analyses indicated that amino, amide, hydroxyl, carboxyl, and oxygenated groups of PH play an important role in the sorption process. Sorption isotherm, kinetic, and thermodynamic parameters of Cu2+ on KOH-modified PH were studied. The kinetic process was well represented by the Logistic model. The maximum sorption was found as 73.16 mg g−1 according to the well-fitting of Langmuir isotherm. Results of sorption and thermodynamic studies indicated that the process was exothermic, being feasible, and spontaneous. KOH-modified PH as an eco-friendly adsorbent had great potential to remove Cu2+ ions from aquatic system.



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Health and environmental risks associated with emerging pollutants and novel green processes



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Glycan distribution and density in native skin's stratum corneum

Abstract

Background

The glycosylation of proteins on the surface of corneocytes is believed to play an important role in cellular adhesion in the stratum corneum (SC) of human skin. Mapping with accuracy the localization of glycans on the surface of corneocytes through traditional methods of immunohistochemistry and electron microscopy remains a challenging task as both approaches lack enough resolution or need to be performed in high vacuum conditions.

Materials and methods

We used an advanced mode of atomic force microscope (AFM), with simultaneous topography and recognition imaging to investigate the distribution of glycans on native (no chemical preparation) stripped samples of human SC. The AFM cantilever tips were functionalized with anti-heparan sulfate antibody and the lectin wheat germ agglutinin (WGA) which binds specifically to N-acetyl glucosamine and sialic acid.

Results

From the recognition imaging, we observed the presence of the sulfated glycosaminoglycan, heparan sulfate, and the glycans recognized by WGA on the surface of SC corneocytes in their native state. These glycans were found associated with bead-like domains which represent corneodesmosomes in the SC layers. Glycan density was calculated to be ~1200 molecules/μm2 in lower layers of SC compared to an important decrease, (~106 molecules/μm2) closer to the surface due probably to corneodesmosome degradation.

Conclusion

Glycan spatial distribution and degradation is first observed on the surface of SC in native conditions and at high resolution. The method used can be extended to precisely localize the presence of other macromolecules on the surface of skin or other tissues where the maintenance of its native state is required.



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Scholar : ΓΛΩΣΣΙΤΙΣ - νέα αποτελέσματα

[PDF] "A Night with Venus, a Lifetime with Mercury" Syphilis–The Overlooked Disease

E Kier-Swiatecka, KU Hansen, J Thorn, EM Pinholt - 2017
… and tongue [14]. Atrophic glossitis, with loss of the filiform and fungiform papillae,
or interstitial glossitis, with fissuring and in duration, may occur together with lingual
leukoplakia, suspicious for carcinoma [14,19]. The typical …
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Methods of Treating Apoptosis and Altering Programmed Cell Death

JR Williams - US Patent App. 15/719,875, 2018
In one aspect, a method of altering programmed cell death includes
administering to an individual in need thereof a therapeutically effective
amount of isomyosmine or a pharmaceutically acceptable sal.
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Scholar : Obstructive sleep apnea - νέα αποτελέσματα

Effects of Coexisting Asthma and Obstructive Sleep Apnea on Sleep Architecture, Oxygen Saturation, and Systemic Inflammation in Women.

F Sundbom, C Janson, A Malinovschi, E Lindberg - … the American Academy of Sleep …, 2018
Abstract Both asthma and obstructive sleep apnea (OSA) are strongly associated with poor
sleep. Asthma and OSA also have several features in common, including airway obstruction,
systemic inflammation, and an association with obesity. The aim was to analyze the effect of
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A case of severe obstructive sleep apnea mimicking REM sleep behavior disorder

Y Fujii, M Okura, H Uemori, M Taniguchi, M Ohi - Rinsho shinkeigaku= Clinical …, 2018
Abstract The rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia
characterized by dream-enacting behaviors related to the loss of the normal generalized
skeletal muscle atonia during REM sleep, and shows REM sleep without atonia (RWA)
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Is anemia in children with sleep disordered breathing actually a consequence of chronic disease?

FA Akcan, Y Dündar, HB Akcan, A Uluat, D Cebeci… - The European Research …, 2018
… [17] Gozal D, Serpero LD, Sans Capdevila O, Kheirandish-Gozal L. Systemic inflammation
in non-obese children with obstructive sleep apnea. Sleep Med 2008;62:489-94 … A suggested
clinical score to predict the severity of adenoid obstruction in children …
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Gene therapy for mucopolysaccharidoses

S Tomatsu, K Sawamoto, HH Chen, RW Mason - Molecular Genetics and Metabolism, 2018
… Tracheal obstruction causes shortness of breath, loud breathing and snoring, sleep
apnea, and look-up to the sky position, leading to the restriction of activity of daily living
(ADL) and life- threatening complications during anesthesia …
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Diagnosis of mucopolysaccharidoses

S Tomatsu, M Stapleton, N Arunkumar, RW Mason… - Molecular Genetics and …, 2018
… Tracheal obstruction causes shortness of breath, loud breathing and snoring, sleep
apnea, and look-up to the sky position, leading to the restriction of activity of daily living
(ADL) and life- threatening complications during anesthesia …
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Healthy Breathing,'Round the Clock: Problems with airway functioning during sleep can hurt children's health. And SLPs, alongside other professionals, are on the …

N Archambault - The ASHA Leader, 2018
… during sleep can hurt children's health. And SLPs, alongside other professionals, are on the front
lines of identification and intervention … Features | February 01, 2018 Healthy Breathing, 'Round
the ClockProblems with airway functioning during sleep can hurt children's health …
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[PDF] Regulation of MicroRNA-378 expression in mature human adipose tissue cells by adiponectin, free fatty acids and dexamethasone

L Xu, L Jiang, K Gu, Z Liu, X Xu - Tropical Journal of Pharmaceutical Research, 2018
… Relationships between Body Fat Distribution, Epicardial Fat and Obstructive Sleep Apnea in
Obese Patients with and without Metabolic Syndrome. Plos ONE 2012; 7(10): e47059-e47059.
4. Spiegelman BM, Flier JS. Obesity and the regulation of energy balance …
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[PDF] KJA

MY Chung, B Park, J Seo, CJ Kim - Korean J Anesthesiol, 2018
… She was suffer- ing from severe obstructive sleep apnea that was intolerable in … This edema of
arytenoid and near structures, most likely due to obstruction of venous drainage caused by the
huge goiter may worsen difficult intubation [8]. Therefore, we could predict dif- ficult …
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Associations among Sleep, Diet, Quality of Life, and Subjective Health.

SL Tan, A Whittal, S Lippke - Health Behavior & Policy Review, 2018
… of a duration yielded a more negative association with poor quality of life than sleeping too little …
an individual is experiencing a lack of sleep, which is presumably connected with poor sleep
quality and … tendency of craving for high-fat diet, he/she is likely to feel sleepy during the …
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[PDF] Energy Expenditure of Healthy Young Men in a Postural Corrective Training (TCP®)

J Baker, S Brock, L Dalleck, E Goulet, R Gotshall… - Evaluation, 2018
… 2004;10(4):319-324. Page 5. 192 3. Del Re MP, Melo, CM, Santos MV, Tufik S, Mello, MT
Applicability of predictive equations for resting energy expenditure in obese patients with
obstructive sleep apnea. Arch Endocrinol Metab. 2017;61(3):257-262. 4. Duarte ACGO …
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Scholar : Laryngomalacia - νέα αποτελέσματα

[HTML] A Rare Case of Laryngeal Tuberculosis in Children

DP Wulandari, R Triasih, RP Nugraha - Otolaryngology Online Journal, 2017
… Endoscopic examination revealed type 1 laryngomalacia (redundancy of arytenoid tissue),
diffuse laryngeal edema, granulation around laryngeal inlet and arytenoid, and irregularities
in vocal cords mucosa with normal vocal cord movement …
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Efficacy of Genz-682452-mediated inhibition of glucosylceramide synthase in a mouse model of Sandhoff disease

J Marshall, JB Nietupski, D Bangari, H Park, K Randall… - Molecular Genetics and …, 2018
… range. Initial physical exam was unremarkable and she was classified as LOPD.
She was managed in the NICU for gastrointestinal reflux, laryngomalacia, hypertonia
and intermittent respiratory distress requiring O2. An ECHO …
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Diagnostic challenges for Pompe disease newborn screening in a pre-term infant

MV Marrero-Stein, D Kronn - Molecular Genetics and Metabolism, 2018
… range. Initial physical exam was unremarkable and she was classified as LOPD.
She was managed in the NICU for gastrointestinal reflux, laryngomalacia, hypertonia
and intermittent respiratory distress requiring O2. An ECHO …
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Late development of oculomotor apraxia in a male adolescent with Gaucher disease

SA Marcellus, JA Bernat, MD Holida - Molecular Genetics and Metabolism, 2018
… range. Initial physical exam was unremarkable and she was classified as LOPD.
She was managed in the NICU for gastrointestinal reflux, laryngomalacia, hypertonia
and intermittent respiratory distress requiring O2. An ECHO …
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Post-transplant iduronidase attenuates skeletal disease in MPS IH

TC Lund, WP Miller, GV Raymond, J Tolar, D Lowe… - Molecular Genetics and …, 2018
… range. Initial physical exam was unremarkable and she was classified as LOPD.
She was managed in the NICU for gastrointestinal reflux, laryngomalacia, hypertonia
and intermittent respiratory distress requiring O2. An ECHO …
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