Brief Communication PD1-related Nephrotoxicity: Optimizing Its Clinical Management Through Histopathologic Features

alwin shared this article with you from Inoreader Brief Communication PD1-related Nephrotoxicity: Optimizing Its Clinical Management Through Histopathologic Features Via Journal of Immunotherapy Immune-related nephrotoxicity (ir-N) is a rare adverse event of immune-checkpoint(s) inhibitors (ICI) therapy and its clinical management is still debated. Among 501 consecutive ICI-treated patients at our Institution, 6 who developed an ir-N with clinical signs suggestive for an acute kidney injury underwent kidney biopsy. Histology showed an acute tubule-interstitial nephritis, simulating the scenario of acute T-cell–mediated kidney transplant rejection. Thus, the management of allograft kidney rejection routinely utilized at our clinic was implemented, leading to rapid renal function improvement. Histologic features supporting the definition of an immune-mediated acute kidney injury in ICI-treated patients may help optimizing the clinical management of ir-N. (Source: Journal of Immuno... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Are Bacteria Just Bystanders in the Pathogenesis of Inflammatory Jaw Conditions?

alwin shared this article with you from Inoreader Are Bacteria Just Bystanders in the Pathogenesis of Inflammatory Jaw Conditions? Via Journal of Oral and Maxillofacial Surgery It is unclear whether certain bacteria initiate the development of inflammatory jaw conditions, or whether these diseases create a milieu for dysbiosis and secondary colonization of indigenous flora. At present, there are no comparative studies on the types of bacteria that colonize different inflammatory jaw conditions. Accordingly, this study aims to identify and compare the types of bacteria isolated in osteomyelitis, osteoradionecrosis, and MRONJ. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Is the Er:YAG laser effective in reducing pain, edema and trismus after removal of impacted mandibular third molars? A meta-analysis.

alwin shared this article with you from Inoreader Is the Er:YAG laser effective in reducing pain, edema and trismus after removal of impacted mandibular third molars? A meta-analysis. Via Journal of Oral and Maxillofacial Surgery : Removal of impacted third molars, can be associated with complications such as pain, edema, trismus, that can increase the morbidity of this procedure. The purpose of this study is to determine whether the Er:YAG laser is effective in reducing pain, swelling and trismus compared to rotary instruments in removing impacted lower third molars (3 LM`s). (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Intraoperative flap warming: The novel use of a sterile cardiac forced warm air blanket for maintaining optimal flap perfusion.

alwin shared this article with you from Inoreader Intraoperative flap warming: The novel use of a sterile cardiac forced warm air blanket for maintaining optimal flap perfusion. Via Journal of Oral and Maxillofacial Surgery The two-team approach in major head and neck/reconstructive surgery can occasionally lead to delays between flap harvest and detachment, due to the complexity and length of the ablative procedure. In order to minimize the potential for flap cooling and the adverse impact on microcirculation, active warming can be beneficial.(1) Intraoperative flap warming to either maintain or improve circulation during free flap harvesting has been performed with a variety of passive and active techniques,(2) however limitations such as a lack of consistent temperature regulation, lack of sterility, inability to directly visualise the flap or the need for acquisition of new equipment for a niche area meant that an ideal solution was lacking. (Source: Journal of Oral and Maxillofacial Surgery) View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Training the pronunciation of L2 vowels under different conditions: the use of non-lexical materials and masking noise

alwin shared this article with you from Inoreader Training the pronunciation of L2 vowels under different conditions: the use of non-lexical materials and masking noise Via Phonetica Phonetica. 2022 Apr 15. doi: 10.1515/phon-2022-2018. Online ahead of print.ABSTRACTThe current study extends traditional perceptual high-variability phonetic training (HVPT) in a foreign language learning context by implementing a comprehensive training paradigm that combines perception (discrimination and identification) and production (immediate repetition) training tasks and by exploring two potentially enhancing training conditions: the use of non-lexical training stimuli and the presence of masking noise during production training. We assessed training effects on L1-Spanish/Catalan bilingual EFL learners' production of a difficult English vowel contrast (/æ/-/ʌ/). The participants (N = 62) were randomly assigned to either non-lexical (N = 24) or lexical (N = 24) training and were fu... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.