Clinical and Experimental Dermatology, EarlyView.
https://ift.tt/2NchJoK
Δευτέρα 3 Σεπτεμβρίου 2018
Melanoma and mastocytosis: is really only a coincidence?
Yellowish‐orange plaques and slack skin in a Chinese boy
Australasian Journal of Dermatology, EarlyView.
https://ift.tt/2CbUtCI
Allergic contact dermatitis caused by propolis‐enriched honey: A case of severe penile oedema
Australasian Journal of Dermatology, EarlyView.
https://ift.tt/2MHtkMZ
Inverted nipples correction with glandular retropapillar flap: demonstration of a technique
Abstract
Inverted nipples constitutes functional and esthetic problems, generating frustration in women regarding breastfeeding and reduced self-esteem and self-efficacy in appearance. Many techniques for surgical correction have already been described. Most use dermal patches of the areola alone or associated with sutures that fit in the base of the papilla. Description of technique for correction of inverted nipple through a series of bilateral or unilateral cases. The surgery presents adequate projection of the nipple, sensitivity and functionality is preserved, and satisfaction with the postoperative result. This study demonstrates an easily reproduced technique that spares local tissue, using a small incision and mobilizes sufficient volume to project the papilla, without deforming the areola.
Level of Evidence: Level IV, therapeutic study
https://ift.tt/2Ch0heu
Placebos mit Heilkraft? Placeboeffekt und -einsatz in der (Schmerz-)Therapie
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 574-578
DOI: 10.1055/a-0636-1776
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
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https://ift.tt/2LZElUQ
Knieendoprothetik: Adduktorenkanalblockade oder lokale Infiltrationsanalgesie?
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 567-568
DOI: 10.1055/a-0668-3904
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Full text
https://ift.tt/2oE9iEG
Grundlagen und Praxis der Neuroanästhesie
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 618-630
DOI: 10.1055/s-0043-111004
Zentrale Aspekte der Anästhesieführung bei neurochirurgischen Operationen sind das Aufrechterhalten der zerebralen Homöostase sowie die Vermeidung sekundärer Hirnschäden. Die wichtigsten Variablen sind zerebraler Metabolismus, zerebraler Blutfluss, zerebraler Perfusionsdruck, zerebrales Blutvolumen und ihr Einfluss auf den intrakraniellen Druck. Die Ausgewogenheit dieser Faktoren ist Ziel bei jeder neurochirurgischen Operation oder Intervention.
[...]
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
https://ift.tt/2NHM0sw
Musikermedizin
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 568-569
DOI: 10.1055/a-0668-3886
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Full text
https://ift.tt/2MLDiNu
Placebo-Nocebo-Ethik für die Patientenkommunikation
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 592-604
DOI: 10.1055/s-0043-121685
Die Patientenaufklärung ist „täglich Brot" des klinisch tätigen Anästhesisten und gleichzeitig ein zentrales Rechtfertigungselement medizinischer Behandlungsmaßnahmen. Durch Auslösen von Placebo- und Noceboeffekten kann sie den Behandlungserfolg aber auch selbst maßgeblich beeinflussen. Einem daraus drohenden Konflikt verschiedener medizinethischer Prinzipien kann mit entsprechenden praktischen Strategien wirksam begegnet werden.
[...]
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
https://ift.tt/2LZDX8Q
Tiefe Relaxierung kann laparoskopische Eingriffe erleichtern
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 568-568
DOI: 10.1055/a-0668-3958
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Full text
https://ift.tt/2MKHkWf
Weiterbildung in der Anästhesie nach Novellierung der Musterweiterbildungsordnung
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 635-638
DOI: 10.1055/a-0591-1169
Schlichtungsstellen für Arzthaftpflichtfragen bieten Patienten, Ärzten und Versicherern eine Möglichkeit, Arzthaftungsstreitigkeiten außergerichtlich zu klären. In der Rubrik „Fälle der Schlichtungsstelle" stellen wir abgeschlossene Fälle aus der Schlichtungsstelle für Arzthaftpflichtfragen der norddeutschen Ärztekammern vor.
[...]
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
https://ift.tt/2NKBoJ8
Critical-Illness-Polyneuromyopathie verschlechtert Outcomes auf Intensivstation
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 569-570
DOI: 10.1055/a-0668-3750
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Full text
https://ift.tt/2MKHexR
Placeboeffekte in der Akutschmerztherapie
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 579-590
DOI: 10.1055/s-0043-121684
Placebo- und Noceboeffekte stehen aktuell sehr im Fokus der klinischen und experimentellen Schmerzforschung. Neuro- sowie psychophysiologische Prozesse scheinen eine wichtige Rolle bei der Entstehung sowie Vermittlung zu spielen. So werden Placebo- und Noceboeffekte im Wesentlichen über das Netzwerk des opioidergen, absteigenden, schmerzmodulierenden Systems vermittelt. Für das Zustandekommen eines Placeboeffektes wiederum werden 3 psychologische Mechanismen verantwortlich gemacht: klassische Konditionierung, soziales Lernen sowie die Schmerzerwartung. Eine offene Analgetikagabe, eine ausführliche Aufklärung über Wirkung und Nebenwirkung (ohne diese zu sehr in den Fokus zu stellen) der im perioperativen Bereich eingesetzten Medikamente und Interventionen sowie eine Einbindung des Patienten in die Therapie (z. B. durch patientenkontrollierte Systeme) können zu einer additiven Verbesserung der Akutschmerztherapie (bis zu 30%) führen.
[...]
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
https://ift.tt/2NNa8d1
50 Jahre Plastische Chirurgie und 25 Jahre Facharzt für Plastische Chirurgie
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 572-572
DOI: 10.1055/a-0667-9094
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Full text
https://ift.tt/2oB2E23
Placeboeffekte bei chronischen Schmerzen: Forschungsstand und klinische Anwendung
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 605-617
DOI: 10.1055/s-0043-121683
Spielte der Placeboeffekt ehemals vorwiegend eine (eher unliebsame) Rolle bei randomisierten kontrollierten Studien, so treten nun vermehrt die mit dem Placeboeffekt verbundenen Chancen in den Vordergrund. Dieser Beitrag bespricht bisherige Forschungserkenntnisse zum Placeboeffekt bei chronischen Schmerzen und zeigt, wie durch eine gezielte Beeinflussung des therapeutischen Kontexts die Wirksamkeit pharmakologisch aktiver Schmerzmedikamente gesteigert werden kann.
[...]
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
https://ift.tt/2NFo2xU
Warnhinweis auf rezeptfreien Schmerzmitteln soll künftig Risiken verringern
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 572-573
DOI: 10.1055/a-0667-9117
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Full text
https://ift.tt/2oE8M9I
Kinderanästhesie: Risikopatienten profitieren von intravenöser Einleitung
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 566-567
DOI: 10.1055/a-0668-3940
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Full text
https://ift.tt/2LQvjt6
Rapid Sequence Induction
Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 631-634
DOI: 10.1055/a-0628-3122
Die „Rapid Sequence Induction and Intubation" (RSI oder RSII) ist bei Patienten mit erhaltener Kreislauffunktion die Standardmethode, um schnellstmöglich eine Atemwegssicherung im Rahmen einer Notfallsituation bzw. Narkose durchzuführen. Ziel einer RSI ist es, eine Aspiration durch die schnelle endotracheale Intubation und den Verzicht auf eine Zwischenbeatmung zu verhindern.Auch heute besitzen nur wenige europäische Länder eine explizite Handlungsempfehlung zur Durchführung einer RSI. In der täglichen klinischen Routine hat sich die Kopfhochlagerung etabliert, die gegenüber den anderen Lagerungsarten gewisse Vorteile bietet. Eine liegende Magensonde sollte i. d. R. während der RSI belassen werden und muss nicht zwingend in den Ösophagus zurückgezogen werden. Wenn keine Magensonde gelegt wurde bzw. bereits lag, ist die Einlage einer Magensonde nach Intubation sinnvoll. Vor der RSI sollte im Normalfall ein Opioid appliziert werden, da die Dosis kreislaufwirksamer Hypnotika und die hämodynamische Stimulation bei der Intubation reduziert werden können.
[...]
Georg Thieme Verlag KG Stuttgart · New York
Article in Thieme eJournals:
Table of contents | Abstract | Full text
https://ift.tt/2MKGSav
Airborne foliar transfer of particular metals in Lactuca sativa L.: translocation, phytotoxicity, and bioaccessibility
Abstract
The uptake, translocation, and human bioaccessibility of metals originating from atmospheric fine particulate matters (PM) after foliar exposure is not well understood. Lettuce (Lactuca sativa L.) plants were exposed to micronic PbO, CuO, and CdO particulate matters (PMs) by the foliar pathway and mature plants (6 weeks old) were analyzed in terms of: (1) metal accumulation and localization on plant leaf surface, and metal translocation factor (TF) and global enrichment factor (GEF) in the plants; (2) shoot growth, plant dry weight (DW), net photosynthesis (Pn), stomatal conductance (Gs), and fatty acid ratio; (3) metal bioaccessibility in the plants and soil; and (4) the hazard quotient (HQ) associated with consumption of contaminated plants. Substantial levels of metals were observed in the directly exposed edible leaves and newly formed leaves of lettuce, highlighting both the possible metal transfers throughout the plant and the potential for human exposure after plant ingestion. No significant changes were observed in plant biomass after exposure to PbO, CuO, and CdO-PMs. The Gs and fatty acid ratio were increased in leaves after metal exposure. A dilution effect after foliar uptake was suggested which could alleviate metal phytotoxicity to some degree. However, plant shoot growth and Pn were inhibited when the plants are exposed to PbO, and necrosis enriched with Cd was observed on the leaf surface. Gastric bioaccessibility of plant leaves is ranked: Cd > Cu > Pb. Our results highlight a serious health risk of PbO, CuO, and CdO-PMs associated with consumption of vegetables exposed to these metals, even in newly formed leaves in the case of PbO and CdO exposure. Finally, the study highlights the fate and toxicity of metal rich-PMs, especially in the highly populated urban areas which are increasingly cultivated to promote local food.
https://ift.tt/2LQlcVa
Zn(II), Pb(II), and Cd(II) adsorption from aqueous solution by magnetic silica gel: preparation, characterization, and adsorption
Abstract
A novel magnetic silica gel adsorbent (Fe3O4-Si-COOH) was successfully prepared by introducing carboxyl group in situ to improve the performance for Pb(II), Zn(II), and Cd(II) adsorption. Infrared spectroscopy (IR), scanning electron microscope (SEM), transmission electron microscope (TEM), thermo-gravimetric analyzer (TGA), the Brunauer-Emmett-Teller (BET) surface area, X-ray diffraction (XRD), and vibrating sample magnetometer (VSM) characterizations suggested that Fe3O4-Si-COOH has been successfully prepared. The adsorption performance was evaluated by batch experiments with different initial concentrations, ionic strength, contact time, and pH. The adsorption kinetics data followed pseudo-second-order model and exhibited a three-stage intraparticle diffusion mode. Isothermal adsorption equilibrium data were best fitted by the Freundlich model and the adsorption capacity were 155, 110, and 93 mg/g (initial concentration 210 mg/L) for Pb(II), Zn(II), and Cd(II), respectively. The result of X-ray photoelectron spectroscopy (XPS) survey spectrum suggested that the main adsorption mechanism is that the H+ of carboxyl groups exchanged with heavy metal ions in the adsorption processes. In addition, the adsorbed Fe3O4-Si-COOH could be regenerated and the adsorption capacity of reused Fe3O4-Si-COOH could maintain 80.3% after five cycles. Hence, the Fe3O4-Si-COOH could be a kind of potential material for removing Pb(II), Zn(II), and Cd(II) from wastewater.
Graphical abstract
https://ift.tt/2Q1UQ5G
Cadmium accumulation and subcellular distribution in populations of Hylotelephium spectabile (Boreau) H. Ohba
Abstract
A pot experiment was conducted among six populations of Hylotelephium spectabile (Boreau) H. Ohba: four from Jiangsu province, one from Shandong province, and one from Shanxi province, China, to investigate the variation of Cd accumulation and subcellular distribution of this species (a newly reported Cd high accumulator). Under five different real Cd-contaminated soils (Cd: 0.93–97.97 mg/kg), results showed considerable differences in Cd concentration in (a) leaf (1.09–50.7 mg/kg), (b) stem (0.61–13.0 mg/kg), and (c) root (1.55–24.5 mg/kg) among the populations. Analysis of subcellular Cd distribution indicated that Cd accumulated in the leaves of H. spectabile was mainly in the cellular debris (44.1 to 53.5%), followed by heat-stable protein (HSP, 20.9 to 29.0%), Cd-rich granules (MRG, 9.9 to 19.5%), heat-denatured protein (6.0 to 8.5%), and organelle fractions (3.1 to 7.4%). The populations of H. spectabile with more Cd partitioned to cellular debris and biological detoxified metal (HSP + MRG) fractions have greater capacity to accumulate Cd, indicating the probable intrinsic mechanism to accumulate Cd. Therefore, H. spectabile has the considerable potential of phytoremediation for Cd-contaminated soils, but screening suitable populations according to soil Cd concentrations is necessary before used for phytoremediation of Cd-contaminated soils.
https://ift.tt/2NKtZJQ
Plant uptake and translocation of perfluoroalkyl acids in a wheat–soil system
Abstract
Application of per- and polyfluoroalkyl substances (PFASs) is shifting to short-chain analogs (C ≤ 6) that raises concerns for their potential ecotoxicological risks. In the present study, pot experiments were carried out to study the effects of perfluoroalkyl acids (PFAAs), including perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkyl sulfonic acids (PFSAs), with different carbon chain lengths (C4, C6, and C8) on the growth of wheat seedlings and their plant uptake and transfer at two spiking levels (200 and 2000 μg/kg soil). Exposure to C4 PFAAs slightly inhibited chlorophyll activity, whereas exposure to C8 PFAAs showed enhancement. The bioaccumulation factors (BAFs) for C4 PFAAs in wheat were over 10, while BAFs for C8 PFAAs were all below 1. Rhizospheric and root to shoot transfer factors for PFAAs were both negatively correlated with their log Kow (p < 0.05). PFCAs exhibited both higher rhizospheric mobility and accumulation potentials than PFSAs of the same chain lengths. Hence, perfluoroalkyl chain governs the mobility of PFAAs in a soil–plant system besides interactions of their head groups, and the substitution with shorter chain PFASs raises concerns for their higher plant accumulation potential that brings higher ecotoxicological and human exposure risks via food chains.
https://ift.tt/2Q1UIDe
The concentration of heavy metals in noodle samples from Iran’s market: probabilistic health risk assessment
Abstract
In the current study, the concentration of heavy metals including lead (Pb), chromium (Cr), cadmium (Cd), and aluminum (Al) in commonly instant noodles consumed in Iran (either imported from other countries or produced in Iran) was investigated by acid digestion method followed by an inductively coupled plasma optical emission spectrometry system (ICP-OES). Also, the associated non-carcinogenic risk due to ingestion of heavy metals for adults and children was estimated by calculating percentile 95% target hazard quotient (THQ) in the Monte Carlo simulation (MCS) method. The average concentrations of Pb, Cr, Cd, and Al in Iranian instant noodle samples were measured as 1.21 ± 0.81, 0.08 ± 0.10, 0.03 ± 0.06, and 9.15 ± 4.82 (mg/kg) and in imported instant noodle samples were 1.00 ± 0.61, 0.07 ± 0.07, 0.04 ± 0.03, and 15.90 ± 0.93 (mg/kg), respectively. A significant difference (p value < 0.05) in the mean concentration of Pb, Cr, Cd, and Al of Iranian instant noodle and imported instant noodle samples was observed. Also, the concentration of Pb, Cr, Cd, and Al in all brands of instant noodle (0.025 mg/kg, 0.050 mg/kg, 0.003 mg/kg, and 0.237 mg/kg, respectively) surpassed the WHO-permitted limits for Pb, Cr, Cd, and Al. Percentile 95% of THQ of Pb, Cr, Cd, and Al for the adult consumers was calculated as 0.012, 0.000007, 0.010, and 1.789; while in the case of children, percentile 95% of THQ of Pb, Cr, Cd, and Al was defined as 0.044, 0.00023, 0.035, and 6.167, respectively. Health risk assessment indicated that both adults and children are at considerable non-carcinogenic health risk for Al (THQ > 1). Therefore, approaching the required strategies in order to reduce the concentration of heavy metals particularly Al in the instant noodle is recommended.
https://ift.tt/2NJlYVI
Clinical Thyroidology®High-Impact Articles
FREE ACCESS through September 14, 2018.
Read Now:
Hypothyroidism Is Associated with Increased Mortality Risk in Individuals 65 Years of Age or Older
Elizabeth N. Pearce
Alemtuzumab, a Monoclonal Antibody to CD52, Frequently Causes Graves' Disease
Jerome M. Hershman
Patients with Differentiated Thyroid Cancer Who Undergo Reoperation for Recurrence Have Increased Mortality
Masha J. Livhits, Michael W. Yeh
Serum TSH Remains Normal in Those without Significant Risk Factors for Thyroid Dysfunction
Angela M. Leung
The post Clinical Thyroidology<sup>®</sup>High-Impact Articles appeared first on American Thyroid Association.
https://ift.tt/2CaCOvg
Efficacy of breast reconstruction with fat grafting: A systematic review and meta-analysis
Breast reconstruction with fat grafting is a new alternative to prosthetic implants and flaps for women with breast cancer. In this study, we investigate the efficacy of fat grafting for breast reconstruction in a meta-analysis.
https://ift.tt/2PyIFMF
Cartilage sparing surgery for melanoma of the external ear
The excision of melanoma of the external ear poses a challenge to surgeons, who must achieve adequate oncological control while minimising impact on form and function. Cartilage preserving surgery is an attractive option as it leaves behind a scaffold for immediate reconstruction with a variety of techniques including full thickness skin grafts (FTSGs) and local flaps. This manuscript will review the literature comparing cartilage sparing surgery with composite excision of skin and cartilage for the treatment of auricular melanoma.
https://ift.tt/2oBKBIU
Readability and quality of breast reduction on-line resources
Many patients are now using the Internet as a resource for health-related information. It is recommended that the readability of patient education materials should be equal to or less than an 11-13-year-old reading level.The aim of this study was to evaluate the readability and quality of websites related to breast reduction.The largest internet search engine was queried for 'breast reduction'. 112 articles from the ten most popular websites were downloaded for analysis. Results from the private cosmetic industry were excluded.
https://ift.tt/2LVM5H4
Comparison of piezosurgery, percutaneous and endonasal continuous osteotomy techniques on a caprine skull model
Osteotomy is a crucial step in rhinoplasty which can have a significant impact on the outcome. In addition to previous percutaneous (external perforating) and endonasal (internal) approaches, piezosurgery has been used in rhinoplasty practice since 2007. This experimental model was planned to compare the three osteotomy techniques.
https://ift.tt/2oBSZbB
Utilization of Installation Wound Vacuum Device for Breast Implant Salvage: Approach and Results
Negative pressure wound therapy allow for an increase in fibroblast migration, a decrease in cell death and stimulation of angiogenesis, all to allow for more rapid wound healing. With irrigating vacs, wounds can be continually washed without painful dressing changes, while concurrently providing the benefit of intermittent negative pressure.
https://ift.tt/2LUHPaP
Shear wave elastography in the diagnosis of the ulnar tunnel syndrome.
An interesting alternative to traditional diagnostic techniques of the upper extremity nerve entrapments might be provided by an ultrasound elastography that started to gain attention in recent research. The aim of this preliminary study was to verify if quantitative analysis of ulnar nerve stiffness with shear-wave elastography can be used to diagnose the ulnar tunnel syndrome, an ulnar nerve neuropathy at the Guyon's canal. The study included 46 patients (39 women) and 39 healthy controls (34 women).
https://ift.tt/2oAUBSD
A SIMPLE METHOD FOR LYMPHEDEMA SELF-MEASUREMENT USING THE ZOZOSUIT BODYSUIT
Dear Editor,
https://ift.tt/2LU6UD4
Obstructive Sleep Apnea and the Metabolic Syndrome: The Road to Clinically-Meaningful Phenotyping, Improved Prognosis, and Personalized Treatment
Obstructive sleep apnea (OSA) is an increasingly prevalent sleep disorder characterized by upper airway obstruction during sleep, resulting in breathing pauses, intermittent hypoxia, and fragmented sleep. In parallel, the constellation of adverse health outcomes associated with prolonged obesity, such as insulin resistance, elevated blood pressure, triglycerides, and reduced high-density lipoprotein cholesterol – termed metabolic syndrome –raises the risk of cardiovascular morbidity and mortality, type 2 diabetes, and all-cause mortality.
https://ift.tt/2MImKFY
Probabilistic risk assessment (Monte Carlo simulation method) of Pb and Cd in the onion bulb (Allium cepa) and soil of Iran
Abstract
Recently, the exposure to heavy metals through the consumption of vegetables has become a global concern. In this regard, the current study was aimed to measure the concentrations of lead (Pb) and cadmium (Cd) in the collected onion bulb samples as well as the surrounded soil using a flame atomic absorption spectrometer (FAAS). Additionally, the target hazard quotient (THQ) for males and females in all age groups of consumers were estimated by using Monte Carlo Simulation (MCS) method. Furthermore, the soil threshold values (STVs) were evaluated to investigate the heavy metal contents in the soil based on the established standard limits. In this context, 45 onion bulbs (HashtBandi region, 25 and Ravang region, 20) and 41 soil (HashtBandi region, 21 and Ravang region, 20) samples were collected (March–May of 2016). The average concentrations of Pb in the onions from HashtBandi and Ravang regions were determined as 0.0052 ± 0.0011 and 0.0061 ± 0.0022 mg/kg, and for Cd were 0.0095 ± 0.0024 and 0.0011 ± 0.0035 mg/kg, respectively. The average concentration of Pb in the soil from HashtBandi and Ravang regions were measured as 3.99 ± 3.77 and 2.03 ± 0.69 mg/kg, and for Cd, the corresponding values were determined as 2.21 ± 3.17 and 2.22 ± 0.92 mg/kg, respectively. The average concentration of Pb and Cd in both investigated onion bulb and soil were lower than Iranian national (onion bulb: Pb = 0.1 mg/kg, Cd = 0.05 mg/kg) and FAO/WHO (onion bulb: Pb = 0.3 mg/kg, Cd = 0.1 mg/kg; soil: Pb = 50 mg/kg, Cd = 0.3 mg/kg) standard limits. Moreover, the THQ and total target hazard quotient (TTHQ) for males and females in all age groups were less than 1 value. Therefore, no risk of the exposure to Pb and Cd as result of onion bulb consumption was reported. STVs for Pb and Cd in the HashtBandi region were calculated as 3.99 and 2.21 mg/kg, and Ravang as 2.03 and 2.22 mg/kg, respectively. Due to the higher calculated STVs for Cd while compared with the established standard limit for the soil, the further revisions regarding the heavy metal standard limits in the soil were recommended.
https://ift.tt/2oCLBwx
The effect of ICT, financial development, growth, and trade openness on CO 2 emissions: an empirical analysis
Abstract
This study investigates the impact of Internet use, financial development, economic growth, and trade openness on carbon dioxide (CO2) emissions in selected European Union (EU) countries. To this end, pooled mean group (PMG) estimator is utilized for panel data from 2001 to 2014. Empirical findings suggest that Internet use has long-run relationship with CO2 emissions and lowering the environmental quality in EU countries. Also, the electricity consumption has a positive and significant effect on CO2 emissions. Moreover, interestingly, economic growth and financial development have a diminishing negative impact on CO2 emission. Heterogeneous panel Granger causality results suggest unidirectional causality running from Internet use to CO2 emissions. The finding implies that the European Union countries did not achieve the level of green information and telecommunication (ICTs) consumption. Overall, the innovative findings indicate that Internet use is raising the threat to the sustainable development. Thus, to curb and mitigate CO2 emissions from Internet use and electricity consumption is the need of time to maintain the sustainable development in EU countries.
https://ift.tt/2oCtve5
Effects of Microcystis aeruginosa on the life history traits and SOD activity of Daphnia similoides sinensis
Abstract
With water eutrophication and global warming, cyanobacteria blooms have occurred frequently, and the interaction between M. aeruginosa and Daphnia has been widely paid attention by researchers. However, the effects of toxic M. aeruginosa on the SOD activity of Daphnia are poorly known. Six D. similoides sinensis clones collected from Lake Junshan and the offspring of two clones were employed. The effects of toxic M. aeruginosa on the life history traits and SOD activities of D. similoides sinensis in the mother and their offspring were studied. Toxic M. aeruginosa could significantly inhibit the life history traits (e.g., body lengths, offspring numbers at first reproduction, cumulative offspring numbers, and the intrinsic rate of population) and induce higher SOD activities of D. similoides sinensis. Compared with the mother, the effects of toxic M. aeruginosa on the life history traits and SOD activities of D. similoides sinensis in the offspring showed obvious differences. Moreover, the adaptability of the offspring to M. aeruginosa indicated also the differences between two clones. Our results suggested that the mother exposed to toxic M. aeruginosa could enhance the fitness of their offspring to Microcystis by maternal effect and was also affected by the D. similoides sinensis genotypes.
https://ift.tt/2wFWD8w
Rarasaponin-bentonite-activated biochar from durian shells composite for removal of crystal violet and Cr(VI) from aqueous solution
Abstract
This paper presents the preparation of composite material and its application for the adsorption of crystal violet and Cr(VI) from aqueous solution onto acid-activated bentonite (AAB) and rarasaponin–bentonite-activated biochar from durian shells composite (RBAB). The influence of initial pH of the solution and the temperature of adsorption on the adsorbents adsorption performance was also studied. Langmuir and Freundlich models could represent the adsorption equilibria equally well. Thermodynamic parameters such as ∆G°, ∆H°, and ∆S° were evaluated based on the adsorption isotherms. The values of ∆G°, ∆H°, and ∆S° for crystal violet adsorption system demonstrate behavior contrary to the Cr(VI) adsorption system. Where crystal violet adsorption is preferred at high temperatures with qmax, value is 518.64 mg/L; while adsorption Cr(VI) is better at low temperature with qmax, value is 106.30 mg/L. Pseudo-first-order and pseudo-second-order kinetic models could represent the kinetic data well.
https://ift.tt/2LRIXfA
A dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves’ disease
Clinical Endocrinology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2CdUWnZ
Thyrotoxicosis after iodine fortification. A 21 year Danish population based study
Clinical Endocrinology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2wCt2wE
Role of cytochrome c in modulating chromium-induced oxidative stress in Oryza sativa
Abstract
Cytochrome c (CYTc) is one of the redox-active molecules responsible for electron transport in plant mitochondria. It is important in the interaction of metal ions with mitochondrial proteome, it is also essential for insights into electron transport during oxidative stress. This study focused on the clarification of interactions of CYTc with metal accumulation and associated modulation of CYTc with reactive oxygen species (ROS) generation in rice seedlings exposed to chromium either hexavalent Cr(VI) or trivalent Cr(III). The result indicates that exposures to both Cr species resulted in significant accumulation of Cr in rice tissues. ROS-dependent growth inhibition of rice seedlings was also evident from both Cr treatments. Changes of CYTc content in roots and shoots maintained almost the same pattern after both Cr exposures. However, dynamically transcriptional levels of rice CYTc genes conducted by real-time quantitative RT-PCR were inconsistent in rice tissues. The results presented here demonstrate that oxidative stresses induced by ROS accumulation do not equally and/or detrimentally influence the perturbations of CYTc content and expression patterns of CYTc genes in rice tissues after Cr exposure, suggesting that the decrease of CYTc levels in roots did not originate ROS accumulation, it may be due to metal-binding properties, while enhancement of CYTc content in shoots was probably a signal of severe growth inhibition owing to ROS accumulation.
https://ift.tt/2Na8Njr
Skin type differences in solar simulated radiation‐induced oxidative stress
British Journal of Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2oHiPLn
Scholar : Shakespeare, Volume 14, Issue 3, September 2018 is now available online on Taylor & Francis Online
Cadmium-accumulator straw application alleviates cadmium stress of lettuce ( Lactuca sativa ) by promoting photosynthetic activity and antioxidative enzyme activities
Abstract
The effects of application of straw derived from cadmium (Cd) accumulator plants (Siegesbeckia orientalis, Conyza canadensis, Eclipta prostrata, and Solanum photeinocarpum) on growth and Cd accumulation of lettuce plants grown under Cd exposure were studied. Treatment with straw of the four Cd-accumulator species promoted growth, photosynthesis, and soluble protein contents and enhanced the activities of peroxidase in leaves of lettuce seedlings. The biomass of shoot of lettuce from high to low in turn is the treatment of C. canadensis straw > S. photeinocarpum straw > S. orientalis > E. prostrata > Control. The Cd content in edible parts (shoots) of the lettuce plants was significantly decreased in the presence of straw from the Cd-accumulator species, except the presence of the straw of E. prostrata. And, the greatest reduction in Cd content in shoots was 27.09% in the S. photeinocarpum straw treatment compared with that of the control. Therefore, application of straw of S. orientalis, C. canadensis, and S. photeinocarpum can promote the growth of lettuce seedlings, and decrease their Cd accumulation, when grown in Cd-contaminated soil, which is beneficial for production of lettuce safe for human consumption.
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Impact of marine and continental sources on aerosol characteristics using an on-board SPAMS over southeast sea, China
Abstract
The chemical composition of atmospheric aerosols was characterized using an on-board single particle aerosol mass spectrometer (SPAMS) over the Southeast China Sea. High-time-resolution observation of marine aerosols was carried out to clarify the source of aerosols and the interaction of marine and continental aerosols. Atmospheric aerosols were determined by the interaction of continental and marine sources over coastal area. Aerosols from continental sources flux into sea surfaces through deposition or diffusion, which results in the rapid decrease of continental aerosols. Five main subtypes of carbonaceous particles are identified as C_Al-Si, C_V-Ni, C_S, C_K, and C_secondary to clarify the impact of marine and continental sources on atmospheric aerosols. High fraction of C_Al-Si and C_secondary is present over XA (Xiamen anchorage), accounting for 23.8% and 18.6% of total carbonaceous particles. Contrarily, the relative percentage of C_S increases as the distance from land to sea increases. The influence of continental aerosols declines, while the contribution of marine aerosols increases as the distance from land to sea increases. Air masses in XA, LSA (land to sea area), SLA (sea to land area), and SA (sea area) were all from ocean during the observation period, resulting in low relative fraction of continental aerosols in SLA, SA, and LSA. High-time-resolution measurement is useful to understand aerosol source types and the impact of marine and continental sources on marine atmosphere aerosols.
https://ift.tt/2MLnL03
Efficacy of high-intensity laser therapy in comparison with conventional physiotherapy and exercise therapy on pain and function of patients with knee osteoarthritis: a randomized controlled trial with 12-week follow up
Abstract
Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders causing pain and functional impairment. The purpose of the study is to compare the effects of high-intensity laser therapy (HILT), conventional physical therapy (CPT), and exercise therapy (ET) on pain and function in patients with KOA. The study was designed as an assessor-blind randomized controlled trial. Ninety-three patients (aged between 50 and 75 years) with proved KOA were included and randomly allocated into three groups, and received 12 sessions of HILT, CPT, or ET. The outcomes were pain intensity measured by visual analog scale (VAS), knee flexion range of motion (FROM), timed up and go test (TUG), 6-min walk test (6MWT), and functionality of knee measured by the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire. Statistical analyses were done to compare the amounts at the baseline, immediately after treatment and after 12 weeks. HILT was significantly more effective than the other groups in decreasing the VAS, increasing FROM and improving the scores of WOMAC (total and function subscale) both after treatment and after 12 weeks. The effect of HILT and CPT on the TUG, 6MWT, and WOMAC pain subscale was not significantly different after treatment, and both were better than ET. HILT was significantly better than the others after follow-up, particularly more effective on the stiffness subscale of WOMAC. HILT combined with exercise therapy, as a useful therapeutic approach, could have positive influences on KOA patients.
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The role of nutrition in inflammatory pilosebaceous disorders: Implication of the skin‐gut axis
Australasian Journal of Dermatology, EarlyView.
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Setting sun pattern in dermoscopy of a scalp nodule
Australasian Journal of Dermatology, EarlyView.
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Decreased Systemic Levels of Endocan-1 and CXCL16 in Psoriasis Are Restored following Narrowband UVB Treatment
Background: In psoriasis, a common immune-mediated disease affecting 2–3% of the population worldwide, there is an increased prevalence of extracutaneous diseases including obesity, the metabolic syndrome, and cardiovascular disease. This is believed to be linked to systemic inflammation. In previous studies, we have explored various markers in plasma and serum to characterize the ongoing systemic inflammation in psoriasis patients compared to controls. We have identified several markers that were altered in psoriasis patients, but which all were unresponsive to narrowband UVB (NB-UVB) treatment. Objective: The objective of the study was to evaluate the effect of NB-UVB treatment on markers of cardiovascular risk and systemic inflammation in psoriasis. Methods: The levels of 17 potential biomarkers with an association with cardiovascular risk were quantitated in plasma from 37 age- and gender-matched psoriasis patients and controls at baseline and in 21 psoriasis patients after 12 weeks of NB-UVB treatment to identify a systemic treatment response. Results: We identified the mediators endocan-1, CXCL16, and sVEGFR1, which were systemically decreased in psoriasis at baseline, as well as FABP3, FABP4, and sIL-1R1, which showed normal baseline levels. After 10–12 weeks of NB-UVB treatment, endocan-1 and CXCL16 were restored to normal levels, while sVEGFR1, FABP3, FABP4, and sIL-1R1 showed a significant reduction. Conclusion: The current study expands the number of potential biomarkers in psoriasis by including a greater number and variety of mediators, approaching the systemic inflammation from additional vantage points, including soluble immune receptors and adipocyte contribution, to provide a more complete picture of the systemic inflammatory state in psoriasis.
Dermatology
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Dermatology
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An investigator‐blinded, randomized, prospective, comparative study of efficacy of four anti‐inflammatory and barrier hand moisturizers in patients with chronic hand dermatitis
Dermatologic Therapy, EarlyView.
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The use of etanercept for treatment of toxic epidermal necrolysis when toxic shock syndrome is in the differential
Dermatologic Therapy, EarlyView.
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Values of body mass index (BMI) and body surface area (BSA) in patients with psoriatic arthritis treated with adalimumab: Preliminary report
Dermatologic Therapy, EarlyView.
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“SENECA” Sinecatechins 10% ointment: A green tea extract for the treatment of actinic keratosis. Case series
Dermatologic Therapy, EarlyView.
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Adipose tissue, fillers, and skin tightening
Dermatologic Therapy, EarlyView.
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Parasitoids of the eucalyptus gall wasp Leptocybe spp.: a global review
Abstract
The genus Leptocybe Fisher & La Salle (Hymenoptera: Eulophidae) and its type species L. invasa were first described in 2004. Leptocybe spp. are global pests of eucalyptus plantations, and parasitoids play an important role in their control. In this review, we describe the species, distribution, biology, ecology and parasitism levels of Leptocybe spp. parasitoids and the problems associated with biological control programmes against Leptocybe spp. Additionally, prospects for the use of conservation or augmentative biological control programmes against Leptocybe spp. are discussed. Worldwide, approximately 23 species of parasitoids of Leptocybe spp. in 7 families and 10 genera have been found to date. Comparing the parasitism levels of the parasitoids showed that Quadrastichus mendeli, Selitrichodes neseri and several (approximately 4) native Megastigmus spp. could be exploited to manage Leptocybe spp. Available information on the Leptocybe spp. parasitoids is expected to improve our understanding related to ongoing studies of biological control programmes against Leptocybe spp.
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Electrode Penetration of the Caudate Nucleus in Deep Brain Stimulation Surgery for Parkinson’s Disease
Objective: To evaluate the possible influence of electrode trajectories penetrating the caudate nucleus (CN) on cognitive outcomes in deep brain stimulation (DBS) surgery for Parkinson's disease (PD). Background: It is currently unclear how mandatory CN avoidance during trajectory planning is. Design/Methods: Electrode trajectories were determined to be inside, outside, or in border region of the CN. Pre- and postoperative neuropsychological tests of each trajectory group were compared in order to evaluate possible differences in cognitive outcomes 12 months after bilateral STN DBS. Results: One hundred six electrode tracks in 53 patients were evaluated. Bilateral penetration of the CN occurred in 15 (28%) patients, while unilateral penetration occurred in 28 (53%). In 19 (36%) patients tracks were located in the border region of the CN. There was no electrode penetration of the CN in 10 (19%) patients. No difference in cognitive outcomes was found between the different groups. Conclusion: Cognitive outcome was not influenced by DBS electrode tracks penetrating the CN. It is both feasible and sensible to avoid electrode tracks through the CN when possible, considering its function and anatomical position. However, penetration of the CN can be considered without major concerns regarding cognitive decline when this facilitates optimal trajectory planning due to specific individual anatomical variations.
Stereotact Funct Neurosurg
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Stereotact Funct Neurosurg
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Feasibility of 5-fluorouracil pharmacokinetic monitoring using the My-5FU PCM™ system in a quaternary oncology centre
Abstract
Purpose
5-Fluorouracil (5FU) drug exposure correlates with treatment response and toxicity in cancer patients. Dosing is based upon body surface area which does not correlate with 5FU pharmacokinetics (PK)/pharmacodynamics. Therapeutic drug monitoring has enabled real-time 5FU dose adjustments: reducing toxicity with increased efficacy. The aim of this study was to assess feasibility of a 5FU monitoring service utilising a commercial kit in a quaternary cancer centre and to compare PK parameters to previously published studies.
Methods
Cancer patients receiving continuous infusional (CI) 5FU with ECOG PS 0–2, and adequate organ function, were eligible. Patients had blood samples taken at t = 0, mid infusion (if feasible) then 2 h pre infusion end. 5FU levels were measured using a commercial kit (My-5FU PCM™). A feasibility questionnaire was completed by trial nurses and toxicity data were recorded at baseline and at the commencement of the next cycle. 5FU pharmacokinetic exposure parameters were calculated.
Results
Twenty patients (12 male; 8 female), median age 62, (range 37–71) had samples taken. Twenty (100%) feasibility forms were available for assessment. Blood samples were taken at 51/69 (74%) specified time points. Ease of sample processing was recorded as easy in all 20 patients. Patient compliance with scheduled visits was 18/20 (90%). One form noted other difficulties with predicting end of infusion time. 19/20 patients had blood samples analysed. Mean measured 5FU AUC (0-Tlast) for 5FU 1 g/m2 with platinum: 35.8 h mg/L (range 28.56–44.26), mean Css 372.2 µg/L (range 297.5–461.0); 5FU 600 mg/m2 with platinum: 12.42 h mg/L (range 6.91–18.29), mean Css 111.0 µg/L (72.0–190.5) and 5FU 2400 mg/m2 as part of FOLFOX ± bevacizumab: 14.75 h mg/L (range 6.74–22.93), mean Css 320.70 µg/L (range 146.5–498.5). One patient had grade 4 neutropenia and one patient without PK parameters experienced febrile neutropenia (grade 4 neutropenia). Mucositis was observed in two patients: [5FU/platinum (1), grade 1, FOXFOX ± bevacizumab (1) grade 1]. Diarrhoea was reported in three patients [5FU/platinum (2) grade 1–2, FOXFOX ± bevacizumab (1) grade 1].
Conclusion
Therapeutic 5FU drug monitoring was feasible using commercial kits and analysers and hence warrants development as a routine standard of care in cancer patients. The variability in the 5FU exposure parameters is consistent with other studies using the My 5FU PCM kit.
https://ift.tt/2LSJVIj
Primary adrenal insufficiency due to bilateral infiltrative disease
Abstract
Purpose
Evidence on clinical presentation, evaluation, and management of patients with primary adrenal insufficiency (PAI) due to bilateral adrenal infiltrative disease is scarce. Our objective was to review the clinical presentation, biochemical work-up, imaging findings, and management of patients with PAI due to infiltrative adrenal disease in order to determine the best diagnostic and management approach.
Methods
Retrospective study of patients with PAI due to bilateral infiltrative adrenal disease referred for adrenal biopsy during 2000–2014 at Mayo Clinic, Rochester, Minnesota. Two additional patients evaluated after 2014 were included.
Results
Seven patients (six males and one female) were diagnosed with PAI caused by bilateral adrenal infiltrative disease at a median age of 54 (range 36–80) years. Duration of symptoms prior to the diagnosis of PAI and initiating treatment was 6 months (range 3 months–4 years). All patients demonstrated bilateral adrenal masses on adrenal imaging. The underlying diagnosis was confirmed by histopathology and included: bilateral adrenal metastases (lung and breast adenocarcinoma), diffuse large B-cell lymphoma, tuberculosis, cryptococcus, histoplasmosis, and, Erdheim-Chester disease.
Conclusion
In patients with newly diagnosed PAI, the differential diagnosis should include bilateral infiltrative adrenal disease, especially when testing for autoimmune adrenalitis is negative, or if there is clinical history suggesting another etiology. Patients who present with known bilateral adrenal infiltrative disease should be counseled and tested for PAI periodically, particularly if presenting with suggestive signs or symptoms.
https://ift.tt/2oA644X
Primary adrenal insufficiency due to bilateral infiltrative disease
Abstract
Purpose
Evidence on clinical presentation, evaluation, and management of patients with primary adrenal insufficiency (PAI) due to bilateral adrenal infiltrative disease is scarce. Our objective was to review the clinical presentation, biochemical work-up, imaging findings, and management of patients with PAI due to infiltrative adrenal disease in order to determine the best diagnostic and management approach.
Methods
Retrospective study of patients with PAI due to bilateral infiltrative adrenal disease referred for adrenal biopsy during 2000–2014 at Mayo Clinic, Rochester, Minnesota. Two additional patients evaluated after 2014 were included.
Results
Seven patients (six males and one female) were diagnosed with PAI caused by bilateral adrenal infiltrative disease at a median age of 54 (range 36–80) years. Duration of symptoms prior to the diagnosis of PAI and initiating treatment was 6 months (range 3 months–4 years). All patients demonstrated bilateral adrenal masses on adrenal imaging. The underlying diagnosis was confirmed by histopathology and included: bilateral adrenal metastases (lung and breast adenocarcinoma), diffuse large B-cell lymphoma, tuberculosis, cryptococcus, histoplasmosis, and, Erdheim-Chester disease.
Conclusion
In patients with newly diagnosed PAI, the differential diagnosis should include bilateral infiltrative adrenal disease, especially when testing for autoimmune adrenalitis is negative, or if there is clinical history suggesting another etiology. Patients who present with known bilateral adrenal infiltrative disease should be counseled and tested for PAI periodically, particularly if presenting with suggestive signs or symptoms.
https://ift.tt/2oA644X
Toxicity potential of particles caused by particle-bound polycyclic aromatic hydrocarbons (PPAHs) at two roadside locations and relationship with traffic
Abstract
This study assessed exposure by the roadside to highly toxic particle-bound polycyclic aromatic hydrocarbons (PPAHs) that are known to adsorb preferentially on fine particles, aerodynamic diameter (dp ≤ 1 μm). The real-time air quality measurements were conducted in March, April, and May 2015 in Kanpur at two busy roadside locations: one outside IIT Kanpur main gate, IG, and another by a residential area, M3. The locations show varying land use type and traffic density. Higher averaged daily concentrations of PM10, PM2.5, and PM1 were observed at IG (PM10 700–800 μg/m3) owing to nature and high density of traffic, and occurrence of biomass burning nearby. Statistically significant relation (R2 > 90%, p < 0.05) between PM1 and PM2.5 highlights the influence of mobile sources on particle load at IG. IG, the busier location, had higher daily averaged concentration of aggregate PPAHs (104 ng/m3) than M3 which is located near a residential area (38 ng/m3). In contrast, the higher average daily value of PC/DC ratio (mass per unit surface area of PPAHs on nanoparticles) at M3 (4.87 ng/mm2) than at IG (4.08 ng/mm2) suggests that PAHs of greater mass occur on particles at M3. Finer particles are known to adsorb pollutants of a larger mass that are likely to be more toxic in case of PAHs suggest that ambient air at M3 has more toxicity potential. However, this inference is not based on chemical analyses, and chemical characteristics must also be taken into account for the detailed assessment of health risk. The multiple path dosimetry model (MPPD-v3.04) reveals that the 99.02% of PM10 inhaled, 77.01% of PM2.5 and 34.54% of PM1 are deposited in the outermost (head) region of the human respiratory tract.
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Economic valuation of noise pollution control policy: does the type of noise matter?
Abstract
As the average noise level and number of noise sources have increased, governments have taken various measures to make soundscapes sustainable. Wise policy decisions require information about the monetary value of noise-control policies. This study elicited people's willingness to pay (WTP) for noise policies, separating traffic noise from residential noise to compare the value of controlling different types of noise. The contingent valuation method was used for the empirical analysis, with data from South Korea. The results show that the monthly mean WTP of respondents was KRW 3392.3 for residential noise reduction and KRW 3507.1 for transport noise reduction; thus, the WTP for the latter is slightly higher than that for the former. Moreover, about 80% of people are unwilling to pay for a noise policy at all, and that high ratio of people with zero WTP must be taken into consideration in the process of policy formulation and implementation. Respondents' experiential and psychological factors were found to be more important than their demographics in explaining their WTP for a noise policy. Potential policy implications based on the analysis results are provided.
https://ift.tt/2Px7UPt
Empirics on linkages among industrialization, urbanization, energy consumption, CO2 emissions and economic growth: a heterogeneous panel study of China
Abstract
This is the first attempt to explore linkages among industrialization, urbanization, energy consumption, CO2 emissions, and economic growth based on estimations in simultaneous equations framework. An economic growth model is extended to incorporate industrialization as shift factor and pollutant emissions as determinant of total factor productivity. A country panel of 30 Chinese provinces/cities and three regional panels, for periods 2000–2016, are estimated employing Augmented Mean Group (AMG) estimator as well as Common Correlated Effects Mean Group (CCEMG) estimator that are robust to both cross-sectional dependence and cointegration. The empirical findings are as follows: (i) the impact of urbanization on economic growth varied from negative to neutral to positive for western-, intermediate-, and eastern-economic zone, respectively, and is known as "urbanization ladder effect," (ii) moving from western to eastern economic zone, as regions develop, industry expansion has more powerful impact on economic growth, and thus, we define it as "industry expansion effect," (iii) industrialization promotes rapid urbanization in less developed and less employment saturated regions; hence, we name it as "employment saturation effect," (iv) economic growth in more developed regions pulled the CO2 emissions downward, while pushed it upward in case of less developed regions; therefore, we call it "growth pull/push effect," and (v) in bidirectional causality between energy consumption and economic growth, the "feedback effect" of economic growth remained dominant for all four panels. Based on empirical findings, policies are suggested for Chinese economy. Further, these policies have potential to extract implications for the rest of the world.
https://ift.tt/2NcKSjr
Correction to: Nematicidal potential of Taraxacum officinale
The original publication of this paper contains a mistake. Data on Table 1 under TR and TL column have been interchanged: that is compounds 1-12 and their amounts refer to TL; compounds 1-8 and related amounts refer to TR (see Fig. 1).
https://ift.tt/2PqW5u4
DFT/TDDFT insights into effects of dissociation and metal complexation on photochemical behavior of enrofloxacin in water
Abstract
Elucidation of the mechanisms underlying the effects of different dissociated forms and metal ion complexation on the photochemical behavior of antibiotics in aqueous media is a key problem and requires further research. We examined the mechanism of the direct photolysis of enrofloxacin (ENRO) in different dissociated forms in water and the impact of metal ions (Mg2+) on the photolysis of ENRO using density functional theory and time-dependent density functional theory. The results showed that different dissociated forms of ENRO exhibited diverse maximum electronic absorbance wavelengths (ENRO3+ (264 nm) < ENRO− (278 nm) < ENRO0 (280 nm) < ENRO2+ (282 nm) < ENRO+ (306 nm)). The calculations of the reaction pathways and activation energies (Ea) in the photolysis of ENRO0/ENRO+/ENRO− showed that defluorination was the main reaction pathway. The removal of cyclopropane was the main reaction pathway for the direct photolysis of ENRO2+/ENRO3+. Furthermore, the presence of Mg2+ was observed to change the order of the maximum electronic absorbance wavelengths and increases the intensities of the ENRO absorbance peaks. Calculations of the photolysis reaction pathways showed that the presence of Mg2+ increased the Ea for the most direct photolysis pathways of ENRO, while its presence decreased the Ea for several partial direct photolysis pathways such as the pathway in which the piperazine ring moiety of ENRO0/ENRO3+ is damaged and the pathway in which cyclopropane is released from ENRO3+. The findings on the photolysis behavior of ENRO in water system have provided useful information on the risk assessment of antibiotics.
https://ift.tt/2wySFO4
Analysis of key genes and signaling pathways involved in Helicobacter pylori‐associated gastric cancer based on The Cancer Genome Atlas database and RNA sequencing data
Helicobacter, EarlyView.
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Anterior Ischemic Optic Neuropathy After Dental Extraction
Background: While often idiopathic, anterior ischemic optic neuropathy occasionally may occur from an identifiable cause. Methods: Observational case report. Results: A 19-year-old woman with unremarkable medical and ophthalmic histories developed visual loss from nonarteritic anterior ischemic optic neuropathy in her right eye after otherwise uneventful dental extraction of the inferior third molars. Conclusions: Anterior ischemic optic neuropathy may rarely occur after dental extraction. Potential pathophysiologic mechanisms of this rare occurrence are discussed. Address correspondence to Rod Foroozan, MD, Baylor College of Medicine, 1977 Butler Boulevard, Houston, TX 77030; E-mail: foroozan@bcm.edu From the Baylor College of Medicine (EK, RF), Houston, Texas. The authors report no conflicts of interest. © 2018 by North American Neuro-Ophthalmology Society
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Summary Insulinomas are rare neuroendocrine tumours that classically present with fasting hypoglycaemia. This case report discusses an un...
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