Effect of different sizes of bioactive glass-coated mesoporous silica nanoparticles on dentinal tubule occlusion and mineralization

Abstract

Objectives

To synthesize two different sizes of bioactive glass-coated mesoporous silica nanoparticles (BGN@MSNs) and to investigate their effects on dentinal tubule occlusion and remineralization.

Materials and methods

Two different sizes of mesoporous silica nanoparticles (MSNs) were synthesized using the Stöber method (368A, 1840A) and coated with bioactive glass nanoparticles (BGNs) using a modified quick alkali-mediated sol-gel method (368B, 1840B). Sensitive tooth disc models were prepared and divided into six groups and the following treatments were applied: group 1—no treatment, group 2—bioglass, group 3—368A, group 4—368B, group 5—1840A, and group 6—1840B. Then, five discs were selected from each group and soaked in 6 wt% citric acid to test acid resistance. Dentinal tubule occlusion and occlusion ratio were observed using field-emission scanning electron microscopy. In vitro mineralization tests using simulated body fluid solution were performed to evaluate the remineralization effect of the treatment.

Results

All samples effectively occluded the dentinal tubule and formed a membrane-like layer. After acid treatment, 1840B (group 6) exhibited the highest rate of dentinal tubule occlusion. Remineralization was observed in 368B and 1840B, and 1840B exhibited the fastest remineralization.

Conclusions

Dentinal tubule remineralization induced by the BGN@MSN biocomposite can be used to stabilize long-term prognosis in dentin hypersensitivity. The 1840B induced the most efficient remineralization, and its smaller size and larger surface area were effective for remineralization.

Clinical relevance

The BGN@MSN biocomposite with its smaller size and larger surface area was more effective for remineralization and dentinal tubule sealing.

https://ift.tt/2N9CjBT

Self-report oral health and disease experience among adults in China and NZ

Abstract

Objectives

Differences in oral health perceptions complicate comparisons of self-reported oral health in countries with considerably different cultures, traditions, and dental care. We compared it in China and New Zealand (NZ), to determine whether adults in those countries differ in how self-report oral health item responses distinguish those with different clinical oral disease states.

Materials and methods

Analysis of representative data on dentate 35–44-year-olds and 65–74-year-olds from the 3rd National Oral Health Survey of China in 2005 (for Sichuan province) and the NZ Oral Health Survey in 2009. Self-rated oral health in the Chinese survey was assessed by asking "Overall, how would you rate your oral health?"(responses: "Very poor," "Poor," "Fair," "Good," and "Very good"). The NZ survey asked "How would you describe the health of your teeth or mouth?" (responses: "Excellent," "Very good," "Good," "Fair," or "Poor"). To enable comparability, these were combined to create a four-category ordinal measure of self-reported oral health. The slope index of inequality (SII) and the relative index of inequality (RII) determined the extent to which the four-category self-report item distinguished those with better or poorer oral status.

Results

A higher proportion of Chinese than NZ 35–44-year-olds rated their oral health as poor or fair, and the NZ proportion rating their oral health as very good was four times that observed among Chinese. The 65–74-year-olds differed even more in their overall responses. For most aspects of clinical disease experience, the two populations were responding similarly to the self-reported oral health item, although the SII and RII values were more pronounced among 35–44-year-olds in NZ than in China; among 65–74-year-olds, both countries were more similar.

Conclusions

Chinese and NZ adults' self-ratings reflect their oral disease experience in largely similar ways, despite considerable absolute differences.

Clinical relevance

These findings support the cross-cultural applicability of self-report oral health measures.

https://ift.tt/2RaLzZB

Relationship between folate concentration and expression of folate-associated genes in tissue and plasma after intraoperative administration of leucovorin in patients with colorectal cancer

Abstract

Purpose

The aim of study was to investigate the relationship between folate concentration and expression of folate-associated genes in tumour, mucosa and plasma of patients with colorectal cancer, after intraoperative administration of bolus leucovorin (LV).

Methods

Eighty patients were randomized into four groups to receive 0, 60, 200, or 500 mg/m² LV, respectively. Tissue and plasma folate concentrations were assessed by LC–MS/MS. Gene expression of ABCC3/MRP3, FPGS, GGH, MTHFD1L, SLC46A1/PCFT, and SLC19A1/RFC-1 was determined using quantitative PCR.

Results

The folate concentration in tumour increased with increasing dosage of LV. Half of the patients treated with 60 mg/m² did not reach a level above the levels of untreated patients. A significant correlation between folate concentration in tumour and mucosa was found in untreated patients, and in the group treated with 60 mg/m² LV. The 5-MTHF/LV ratio correlated negatively with folate concentration in mucosa, whereas a positive correlation was found in tumour of patients who received 200 or 500 mg/m² LV. A positive correlation was found between folate concentration and expression of all genes, except MTHFD1L, in patients who received LV. There was a negative correlation between 5-MTHF concentration in plasma of untreated patients and expression of GGH and SLC46A1/PCFT in tumour.

Conclusions

The results indicate the possibility of using the individual plasma 5-MTHF/LV ratio after LV injection as a surrogate marker for tissue folate concentration. Expression of several folate-associated genes is associated with folate concentration in tissue and plasma and may become useful when predicting response to LV treatment.

https://ift.tt/2NNAgJ0

Endogenous IL-10 maintains immune tolerance but IL-10 gene transfer exacerbates autoimmune cholangitis

Publication date: Available online 28 September 2018

Source: Journal of Autoimmunity

Author(s): Yu-Hsin Hsueh, Hung-Wen Chen, Bi-Jhen Syu, Chia-I. Lin, Patrick S.C. Leung, M. Eric Gershwin, Ya-Hui Chuang

Abstract

The immunomodulatory effect of IL-10 as an immunosuppressive and anti-inflammatory cytokine is well known. Taking advantage of our established mouse model of autoimmune cholangitis using 2-octynoic acid conjugated ovalbumin (2-OA-OVA) induction, we compared liver pathology, immune cell populations and antimitochondrial antibodies between IL-10 knockout and wild type mice immunized with 2-OA-OVA. At 10 weeks post immunization, portal inflammation and fibrosis were more severe in 2-OA-OVA immunized IL-10 knockout mice than in wild type mice. This was accompanied by significant higher levels of collagen I and III expression, T, NK and NKT subsets in liver and IgG anti-mitochondrial autoantibodies (AMAs) compared to 2-OA-OVA immunized wild type mice, suggesting that endogenous IL-10 is necessary for the maintenance of immune tolerance in primary biliary cholangitis (PBC). Further, we investigated whether administration of exogenous IL-10 could prevent PBC by administration of IL-10 expressing recombinant adeno-associated virus (AAV-IL-10) either 3 days before or 3 weeks after the establishment of liver pathology. Interestingly, administration of AAV-IL-10 resulted in increased liver inflammation and fibrosis, accompanied by increases in IFN-γ in liver CD4⁺ T cell, granzyme B, FasL, and CD107a in liver CD8⁺ T and NKT cells, and granzyme B and FasL in liver NK cells of AAV-IL-10 administered mice compared with control mice. Furthermore, administration of AAV-IL-10 significantly increased levels of proinflammatory cytokines and chemokines (IFN-γ, TNF-α, CXCL9 and CXCL10) and collagen I and III production in naïve mice, together with increase in immune cell infiltration and collagen deposition in the liver, suggesting a role of IL-10 in fibrosis. In conclusion, our data demonstrate that endogenous IL-10 is critical in the maintenance of immune tolerance but exogenous administration of IL-10 exacerbates liver inflammation and fibrosis. Furthermore, the distinctive presence of inflammatory immune cell populations and collagen expression in AAV-IL-10 treated naïve mice cautions against the clinical use of exogenous IL-10 in patients with autoimmune cholangitis.

https://ift.tt/2OiGnVf

Scholar : Acta Odontologica Scandinavica, Volume 76, Issue 7, October 2018 is now available online on Taylor & Francis Online

The online platform for Taylor & Francis Online content Acta Odontologica Scandinavica, Volume 76, Issue 7, October 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: Original Article Approximal sealings on lesions in neighbouring teeth requiring operative treatment: an in vitro study Alvaro Cartagena, Azam Bakhshandeh & Kim Rud Ekstrand Pages: 459-465 | DOI: 10.1080/00016357.2018.1436191 Association between age at asthma diagnosis and tooth loss Hyungkil Choi, Kwang-Hak Bae & Jeong-Woo Lee Pages: 466-472 | DOI: 10.1080/00016357.2018.1436723 Effect of resin infiltration and microabrasion on the microhardness, surface roughness and morphology of incipient carious lesions Basak Yazkan & R. Banu Ermis Pages: 473-481 | DOI: 10.1080/00016357.2018.1437217 A method for preventive intervention regarding temporomandibular pain and dysfunction Saghafi Ellie & Mejersjö Christina Pages: 482-487 | DOI: 10.1080/00016357.2018.1439529 A new methodology for the measurement of the root canal curvature and its 3D modification after instrumentation Asterios Christodoulou, Georgios Mikrogeorgis, Triantafillia Vouzara, Konstantinos Papachristou, Christos Angelopoulos, Nikolaos Nikolaidis, Ioannis Pitas & Kleoniki Lyroudia Pages: 488-492 | DOI: 10.1080/00016357.2018.1440321 Cumulative use of salivary markers with an adaptive design improves detection of periodontal disease over fixed biomarker thresholds Ulvi Kahraman Gürsoy, Pirkko J. Pussinen, Veikko Salomaa, Sanna Syrjäläinen & Eija Könönen Pages: 493-496 | DOI: 10.1080/00016357.2018.1441436 Review Article Augmented reality in dentistry: a current perspective Ho-Beom Kwon, Young-Seok Park & Jung-Suk Han Pages: 497-503 | DOI: 10.1080/00016357.2018.1441437 Original Article Illicit drug use and traumatic dental injuries in adolescents Mareeshty Damarasingh, Wagner Marcenes, Stephen A. Stansfeld & Eduardo Bernabé Pages: 504-508 | DOI: 10.1080/00016357.2018.1444200 Relationship between depth of approximal caries lesions and presence of bacteria in the dentine in primary and permanent posterior teeth: a radiographic examination with microbiological evaluation Azam Bakhshandeh, Isabela Floriano, Mariana Minatel Braga, Kristine Arnholdt Thorlacius & Kim Rud Ekstrand Pages: 509-514 | DOI: 10.1080/00016357.2018.1444201 Ten-year follow-up on adoption of endodontic technology and clinical guidelines amongst Danish general dental practitioners Merete Markvart, Helena Fransson, EndoReCo & Lars Bjørndal Pages: 515-519 | DOI: 10.1080/00016357.2018.1447684 Distribution of Porphyromonas gingivalis fimA genotypes in patients affected by rheumatoid arthritis and periodontitis José Luis Ayala-Herrera, Carlos Abud-Mendoza, Roberto F. Gonzalez-Amaro, Leon Francisco Espinosa-Cristobal & Rita Elizabeth Martínez-Martínez Pages: 520-524 | DOI: 10.1080/00016357.2018.1469788 Association of risk factors with temporomandibular disorders in the Northern Finland Birth Cohort 1966 Päivi Jussila, Jarno Knuutila, Sampo Salmela, Ritva Näpänkangas, Jari Päkkilä, Pertti Pirttiniemi & Aune Raustia Pages: 525-529 | DOI: 10.1080/00016357.2018.1479769 Self-reportance of temporomandibular disorders in adult patients attending general dental practice in Sweden from 2011 to 2013 Bengt Adèrn, Ava Minston, Eva Nohlert & Åke Tegelberg Pages: 530-534 | DOI: 10.1080/00016357.2018.1487076 Letter to the Editor Intraosseous anaesthesia as a primary technique for mandibular posterior teeth with symptomatic irreversible pulpitis Thierry Collier Pages: 535-537 | DOI: 10.1080/00016357.2018.1489558 A response for Effect of intraosseous injection versus inferior alveolar nerve block as primary pulpal aesthesia of mandibular posterior teeth with symptomatic irreversible pulpitis: a prospective randomized clinical trial Alireza Farhad, Hamid Razavian & Maryam Shafiee Pages: 538-538 | DOI: 10.1080/00016357.2018.1497578 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Japan Singapore Skin Conference 2019

Publication date: October 2018

Source: Journal of Dermatological Science, Volume 92, Issue 1

Author(s):

https://ift.tt/2NTv72h

The Editor's Choice

Publication date: October 2018

Source: Journal of Dermatological Science, Volume 92, Issue 1

Author(s):

https://ift.tt/2N95ODV

Editorial board

Publication date: October 2018

Source: Journal of Dermatological Science, Volume 92, Issue 1

Author(s):

https://ift.tt/2NOOJEH

Scholar : African Journal of Marine Science, Volume 40, Issue 3, September 2018 is now available online on Taylor & Francis Online

The online platform for Taylor & Francis Online content African Journal of Marine Science, Volume 40, Issue 3, September 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: Research Papers Occurrence and ingestion of microplastics by zooplankton in Kenya's marine environment: first documented evidence C Kosore, L Ojwang, J Maghanga, J Kamau, A Kimeli, J Omukoto, N Ngisiag'e, J Mwaluma, H Ong'ada, C Magori & E Ndirui Pages: 225-234 | DOI: 10.2989/1814232X.2018.1492969 Evaluating the effects of catch-and-release angling on Cape stumpnose Rhabdosargus holubi in a South African estuary NK Arkert, A-R Childs, MC Parkinson, AC Winkler, E Butler, S Mannheim & WM Potts Pages: 235-244 | DOI: 10.2989/1814232X.2018.1494041 Macroparasites of angelfish Brama brama (Bonnaterre, 1788) in the southern Benguela Current ecosystem AL Mackintosh, CC Reed, MAI Nunkoo, PH King & CD van der Lingen Pages: 245-252 | DOI: 10.2989/1814232X.2018.1499551 Wintertime rates of net primary production and nitrate and ammonium uptake in the southern Benguela upwelling system RF Flynn, JM Burger, K Pillay & SE Fawcett Pages: 253-266 | DOI: 10.2989/1814232X.2018.1502095 Effect of graded levels of dietary carbohydrate on growth, feed utilisation and intestinal microbial community structure in dusky kob Argyrosomus japonicus fed a pelleted diet NC Mabasa, PJ Britz, CLW Jones & A Nel Pages: 267-277 | DOI: 10.2989/1814232X.2018.1503969 Assessment of the likely sensitivity to climate change for the key marine species in the southern Benguela system K Ortega-Cisneros, S Yokwana, W Sauer, K Cochrane, A Cockcroft, NC James, WM Potts, L Singh, M Smale, A Wood & G Pecl Pages: 279-292 | DOI: 10.2989/1814232X.2018.1512526 Data-moderate assessments of Cape monkfish Lophius vomerinus and west coast sole Austroglossus microlepis in Namibian waters JN Kathena, A Kokkalis, MW Pedersen, JE Beyer & UH Thygesen Pages: 293-302 | DOI: 10.2989/1814232X.2018.1512527 Socioeconomic dynamics of the Ghanaian tuna industry: a value-chain approach to understanding aspects of global fisheries E Drury O'Neill, NK Asare & DW Aheto Pages: 303-313 | DOI: 10.2989/1814232X.2018.1513866 Short communication Quantifying the largest aggregation of giant trevally Caranx ignobilis (Carangidae) on record: implications for management R Daly, CAK Daly, RH Bennett, PD Cowley, MAM Pereira & JD Filmalter Pages: 315-321 | DOI: 10.2989/1814232X.2018.1496950 Environmental responses of jellyfish polyps as drivers of medusa populations off the coast of Namibia L Ziegler & MJ Gibbons Pages: 323-329 | DOI: 10.2989/1814232X.2018.1500397 Coral reefs of the Glorieuses Islands, western Indian Ocean MH Schleyer, L Bigot & Y Benayahu Pages: 331-339 | DOI: 10.2989/1814232X.2018.1512525 Corrigendum Corrigendum Pages: 341-341 | DOI: 10.2989/1814232X.2018.1521505 Hoping to have your article read by anyone, anywhere and at any time? Find out more about publishing open access with Ecosystem Health and Sustainability. To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

CDKN2A germline mutations are not associated with poor survival in an Italian cohort of melanoma patients

Publication date: Available online 28 September 2018

Source: Journal of the American Academy of Dermatology

Author(s): Bruna Dalmasso, Lorenza Pastorino, Giulia Ciccarese, Virginia Andreotti, Federica Grillo, Luca Mastracci, Francesco Spagnolo, Alberto Ballestrero, Paola Queirolo, William Bruno, Paola Ghiorzo

Background

Cyclin dependent kinase inhibitor 2A gene (CDKN2A) germline mutations have recently been associated with poor survival in patients with melanoma. Despite the high mutation rate in our cohort (up to 10% in patients with apparently sporadic melanoma), information on the impact of CDKN2A on survival in this cohort is lacking.

Objective

To investigate whether poor survival associated with CDKN2A germline mutations was confirmed in a high mutation–prevalence cohort of Italian patients with melanoma undergoing a mutation-based follow-up.

Methods

A total of 1239 patients with cutaneous melanoma were tested for CDKN2A mutational status and then assigned to a follow-up scheme according not only to family history but also to CDKN2A mutational status, as follow-up intervals were more frequent for CDKN2A germline mutation–positive (MUT⁺) patients. From this cohort, we selected 106 MUT⁺ patients (with familial melanoma or apparently sporadic melanoma) and 199 CDKN2A germline mutation–negative (MUT^–) patients with sporadic melanoma who were matched by age and sex and had a similar tumor stage distribution.

Results

We found no difference in overall survival (hazard ratio, 0.85; 95% confidence interval, 0.48-1.52; P = .592,) or melanoma-specific survival (hazard ratio, 0.86; 95% confidence interval, 0.38-1.95; P = .718,) between MUT⁺ and MUT^– patients. MUT⁺ patients were more likely to develop multiple melanomas and to undergo surgical excision of dysplastic nevi than were MUT^– patients.

Limitations

Retrospective study.

Conclusion

CDKN2A mutations were not associated with survival in our cohort.

https://ift.tt/2OZ0d50

Scholar : International Journal of Heritage Studies, Volume 24, Issue 10, December 2018 is now available online on Taylor & Francis Online

The online platform for Taylor & Francis Online content International Journal of Heritage Studies, Volume 24, Issue 10, December 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: Original Articles Dilemma of local socio-economic perspectives in management of historic ruins in Kilwa Kisiwani World Heritage Site, Tanzania Noel Biseko Lwoga Pages: 1019-1037 | DOI: 10.1080/13527258.2018.1430604 Articles Identifying sites at risk from illicit metal detecting: from CRAVED to HOPPER Louise Grove, Adam Daubney & Alasdair Booth Pages: 1038-1052 | DOI: 10.1080/13527258.2018.1475408 Intramuros: memory, violence and national becoming in Manila Robert Mason & Lauren Istvandity Pages: 1053-1067 | DOI: 10.1080/13527258.2018.1475405 Learning from cultural engagements in community-based heritage scholarship Alicia Ebbitt McGill Pages: 1068-1083 | DOI: 10.1080/13527258.2018.1475413 Book Reviews California mission landscapes: race, memory, and the politics of heritage Elizabeth Kryder-Reid, Minneapolis, University of Minnesota Press, 2016, xv + 355 pp., $35.00 (paperback), ISBN 978-0-8166-3797-3 James I. Deutsch Pages: 1084-1085 | DOI: 10.1080/13527258.2018.1475412 Book review Ross J. Wilson Pages: 1085-1087 | DOI: 10.1080/13527258.2018.1475415 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : ΜΑΣΤΟΕΙΔΙΤΙΣ - νέα αποτελέσμ

[PDF] AMSER Case of the Month July 2018

B Park, K Xie - 2018

… T1 Post Contrast Final Diagnosis Left sphenoid/ethmoid sinusitis, mastoiditis and left
temporal subdural empyema Page 9 … Etiology – Bacterial infections gain access to the
subdural space by direct extension of frontal sinusitis, mastoiditis, otitis media or most …

Low-dose non-contrast examination of the temporal bone using volumetric 320-row computed tomography

B Pirimoglu, R Sade, MS Sakat, G Polat, M Kantarci - Acta Radiologica, 2018

Background 320-row volume computed tomography (CT) allows CT dose to be reduced
while maintaining image quality. Purpose To evaluate image quality of low-dose n...

[PDF] Septic thrombophlebitis of the sigmoid sinus after vestibular schwannoma resection: A case report and

TP Brito, HF Pauna, RC Pereira, RV de Araújo Rego…

… Correspondence to: Henrique Furlan Pauna, Department of
Otorhinolaryngology, Head and Neck Surgery, University of Campinas
(UNICAMP), Campinas, São Paulo, Brazil, E-mail: h_pauna@hotmail.com …

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ЛС Овчаренко, АО Вертегел, ТГ Андрієнко…

… 13(1): 1—4. https://ift.tt/2IsNQM8; PMid:23355360.
4. Gorphe P, de Barros A, Choussy O et al. 2012. Acute mastoiditis in
children: 10 years experience in a French tertiary university referral center …

[PDF] Fiebre de origen desconocido en niños

JR Contreras, ID Lorenzo

… Infecciones Bacterianas Víricas Fúngicas Parasitarias Tuberculosis
Brucelosis Fiebre tifoidea Bartonelosis Osteomielitis Endocarditis
Leptospirosis Abscesos abdominales Mastoiditis Pielonefritis Sinusitis …

 

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Scholar : Laryngotracheal reconstruction - νέα αποτελ

Management of Locally Advanced Thyroid Cancer

AR Marcadis, J Cracchiolo, AK Shaha - Evidence-Based Endocrine Surgery, 2018

… of the cricoid cartilage involved or destructed by tumor, a more extensive
intervention is necessary, with some authors advocating total laryngectomy
to avoid airway stenosis, and others suggesting that partial laryngeal resection …

Neonatal Stridor: Diagnosis and Management

J Bhatt, JD Prager - Clinics in Perinatology, 2018

Skip to Main Content …

Polysomnography Provides Useful Clinical Information in the Liberation from Respiratory Technology: A Retrospective Review

A Bashir, JK Henningfeld, NE Thompson, LA D'Andrea - Pediatric Pulmonology

… congenital central hypoventilation syndrome; CHD; congenital heart disease; CLD;
chronic lung disease; EtCO 2; end‐tidal CO 2; HMV; home mechanical ventilation; LTR;
laryngotracheal reconstruction; NIH; national institute of health; …

 

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Scholar : intitle:laryngeal - new results

A method for intraoperative recording of the laryngeal adductor reflex during lower brainstem surgery in children

P Costa, PP Gaglini, P Tavormina, F Ricci, P Peretta - Clinical Neurophysiology, 2018

LAR represents the thyroarytenoid muscle response to different stimulation types
(electrical, mechanical or chemical) of the laryngeal mucosa and it is considered to
be a mechanism of laryngeal protection (Matsuzaki et al., 2014). It is generally …

Laryngeal Adductor Reflex And Future Projections for Brainstem Monitoring. Reply to "A method for intraoperative recording of the laryngeal adductor reflex during …

S Ulkatan, MJ Tellez, C Sinclair - Clinical Neurophysiology, 2018

In their Letter to the Editor, Costa et al.(2018) report on using the laryngeal adductor
reflex (LAR), along with standard, methodologies, to monitor vagus nerve pathways
in three pediatric patients during the removal of large 4th ventricle tumors …

Longitudinal Evaluation of Quality of Life in Laryngeal Cancer Patients Treated with Surgery

AT Bui, KSY Ji, CT Pham, KM Le, TX Tong, WT Lee - International Journal of Surgery, 2018

Background There is insufficient prospective data on quality of life outcomes for
laryngeal cancer patients undergoing surgery, especially in low-and middle-income
countries. This limits clinical and patient decision-making, and survivorship …

Performance of Air Seal of Flexible Reinforced Laryngeal Mask Airway in Thyroid Surgery Compared With Endotracheal Tube: A Randomized Controlled Trial

Y Gong, J Wang, X Xu, J Li, R Song, J Yi - Anesthesia & Analgesia, 2018

BACKGROUND: Flexible reinforced laryngeal mask airway (FLMA®) has gained
popularity in thyroid surgery, but air leak and displacement are still concerns.
METHODS: In this randomized, single-blinded, noninferiority, controlled trial, we …

Juvenile Laryngeal Papillomatosis is More Aggressive Than the Adult Variant

VNR El Achkar, A Duarte, R Carlos, JE Léon… - Oral Surgery, Oral Medicine …, 2018

Objective: Laryngeal papillomatosis (LP) may occur in an aggressive form with a risk
of spreading to the lungs, respiratory obstruction, and malignant transformation. To
identify the more aggressive cases and guide treatments, laryngoscopic scores have …

[PDF] Laryngopharyngeal Reflux and Functional Laryngeal Disorder: Perspective and Common Practice of the General Gastroenterologist

DA Patel, M Blanco, MF Vaezi - Gastroenterology & Hepatology, 2018

Laryngopharyngeal reflux (LPR) is an extraesophageal variant of gastroesophageal
reflux disease that is associated with chronic cough, hoarseness, dysphonia,
recurrent throat clearing, and globus pharyngeus. Due to nonspecific symptoms …

Laryngeal Allergic Mucoid Impaction in Bilateral False Vocal Cords

D Metry, I Ghleilib, O Nwogbo, S Kavuri, S Sharma… - American Journal of Clinical …, 2018

Mucoid impaction is a well-known source of bronchial and bronchiolar obstruction,
particularly in patients with bronchial asthma. It is a clinical syndrome characterized
by inspissated mucus occluding a narrowed segmental bronchus. If the impacted …

Primary Laryngeal Tuberculosis: A Series of 15 Cases

R Agarwal, L Gupta, M Singh, N Yashaswini, A Saxena… - Head and Neck Pathology, 2018

Tuberculosis usually involves the lungs, but can also involve various other organs.
Extra pulmonary tuberculosis is very rarely confined to the larynx in the absence of
an associated pulmonary lesion. In this retrospective study, clinicopathological …

 

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