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Κυριακή 15 Ιουλίου 2018

Correction to: A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer

The original version of this article unfortunately contained a mistake. The co-authors' names were incorrect.



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Assessment of healthiness among long term inhabiting army soldiers in dry zone of Sri Lanka.

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Assessment of healthiness among long term inhabiting army soldiers in dry zone of Sri Lanka.

BMC Res Notes. 2018 Jul 13;11(1):474

Authors: Jayaweera JAAS, Joseph A

Abstract
OBJECTIVES: Military personnel, because of the unique nature of their duties, are reluctant to face stressors. Living in hot and humid conditions they frequently suffer dehydration. Army soldiers living in dry zone of Sri Lanka, were screened for chronic kidney disease (CKD), common non-communicable diseases and methicillin resistant Staphylococcus aureus (MRSA) colonization. Albumin creatinine ratio > 30 mg/g urine taken as cut-off for detection of CKD.
RESULTS: Screened 417 soldiers, all were men and body mass index were 21.4 ± 2.2 kg/m2. They smoke 0.5 ± 0.1 pack years while consume alcohol 32 ± 3 units/week and were having 100/min average daily moderate physical activity. Eight of them (0.2%) were having essential hypertension, 4 (0.1%) of them were having diabetes mellitus. Blood cholesterol was within normal range. CKD unknown etiology (CKDu) prevalence among screened army soldiers was 0.009. All were from native army recruits. Further, 71.2% had MRSA colonization. In a group of middle aged army recruits, despite tobacco smoking and moderate level of alcohol consumption while continuously having healthy dietary practices with physical activities would leads to low prevalence of communicable diseases. Further, compared to native group of solders, visitors but living long time recruits CKDu incidence is zero.

PMID: 30005685 [PubMed - in process]



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Graphical Abstracts



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Meet Our Editorial Board Member



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Potassium Channels and CNS Diseases



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The Large Conductance Calcium- and Voltage-activated Potassium Channel (BK) and Epilepsy



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K+ Channels of Müller Glial Cells in Retinal Disorders



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Lysosomal Potassium Channels: Potential Roles in Lysosomal Function and Neurodegenerative Diseases



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Oxidation of Potassium Channels in Neurodegenerative Diseases: A Mini-Review



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The Yin and Yang of BK Channels in Epilepsy



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Vitamin D's Molecular Action Mechanism in Attention-deficit/Hyperactivity Disorder: A Review of Evidence



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Ultra-micronized Palmitoylethanolamide Effects on Sleep-wake Rhythm and Neuropathic Pain Phenotypes in Patients with Carpal Tunnel Syndrome: An Open-label, Randomized Controlled Study



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Cerebrolysin and Aquaporin 4 Inhibition Improve Pathological and Motor Recovery after Ischemic Stroke



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Monoamine Involvement in the Antidepressant-Like Effect of β-Caryophyllene



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Penile lymphoedema: approach to investigation and management

Clinical and Experimental Dermatology, EarlyView.


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How does sleep restriction therapy for insomnia work? A systematic review of mechanistic evidence and the introduction of the Triple-R model

For over 30 years sleep restriction therapy (SRT) has been used to treat insomnia but we know very little about how this therapy exerts its effects. When SRT was first described, it was hypothesised to treat insomnia by addressing four key factors: strengthening homeostatic sleep pressure, inhibiting perpetuating practices (excessive time in bed), attenuating hyperarousal and tightening regulatory control of sleep by the endogenous circadian pacemaker. We conducted a systematic literature review in search of evidence for these putative mechanisms-of-action.

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Corrigendum to ``Patient-rated long-term results after complete denervation of the wrist'' [Journal of Plastic, Reconstructive & Aesthetic Surgery Volume 71 Issue 1 (2018) 57–61]

The authors regret that after reevaluation of the paper we unfortunately found an obvious mistake concerning a missing author and the order of appearance. The author was added and a change in the order had to be corrected. The authors would like to apologise for any inconvenience caused.

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Cosmetics, Vol. 5, Pages 43: Development of Antidandruff Shampoo from the Fermented Product of Ocimum sanctum Linn.

Cosmetics, Vol. 5, Pages 43: Development of Antidandruff Shampoo from the Fermented Product of Ocimum sanctum Linn.

Cosmetics doi: 10.3390/cosmetics5030043

Authors: Chanun Punyoyai Sasithorn Sirilun Panuwan Chantawannakul Wantida Chaiyana

This study aimed to investigate Malassezia furfur inhibitory activity of the fermented product from Ocimum sanctum and develop an antidandruff shampoo. The fermented product was obtained by the fermentation process of the aerial part of O. sanctum. Total soluble protein was detected in the fermented product with the amount of 65.32 ± 0.14 mg/100 mL, whereas there was no organic acid. The inhibitory activity against four strains of M. furfur (No. 133, 656, 6000, and 7966) of the fermented product and shampoos containing the fermented product were investigated by broth dilution and agar diffusion method, respectively. The fermented product possessed high antifungal activity with the minimum inhibitory concentrations for 50% (MIC50) of M. furfur 133, 656, 6000, and 7966 of 0.125, 0.25, 0.125, and 0.125 mg/mL, respectively. Interestingly, the antifungal activity against M. furfur 656 was comparable to that of ketoconazole. Shampoo formulation C, which was the best formulation in terms of characteristics and stability, obtained a high level of satisfaction scores in terms of hair smoothness, hair shine, ease in combing, frizz reduction, and triboelectric reduction while brushing. Additionally, the shampoo containing 2% (w/w) of the fermented product of O. sanctum also possessed inhibitory activity against M. furfur 133, 656, 6000, and 7966 with inhibition zones of 13.2 ± 1.6, 12.8 ± 1.1, 18.7 ± 0.3, and 17.0 ± 1.1 mm respectively. Therefore, this shampoo was suggested for use as an antidandruff shampoo.



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