Study on the clinical characteristics of isolated congenital anosmia

xlomafota13 shared this article with you from Inoreader Study on the clinical characteristics of isolated congenital anosmia Via Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 May 7;56(5):442-446. doi: 10.3760/cma.j.cn115330-20210219-00070. ABSTRACT Objective: To retrospectively analysely the electrophysiological and imaging features of isolated congenital anosmia (ICA) and to assess the clinical phenotypic characteristics and classification of ICA. Methods: Clinical data of 30 ICA patients in Beijing Anzhen Hospital from 2012 to 2019 was retrospectively reviewed, including 13 males and 17 females, aged (35±19) years. The control group consisted of 30 healthy people from medical examination center, including 13 males and 17 females, aged (39±14) years. The clinical characteristics of ICA were analyzed using Sniffin' Sticks test, olfactory event-related potentials (oERPs), trigeminal event-related potentials (tERP) and olfactory pathway MRI. SPSS 17.0 software was used to compare the difference of olfactory function between the two groups. Th e correlation between olfactory bulb, olfactory sulcus structure and age was observed, and the clinical phenotype characteristics of ICA patients were analyzed. Results: The subjective olfactory function was completely lost in ICA patients. oERP was absent in all of the ICA patients, but showed normal N1 and P2 waves in controls. tERP could be evoked in 63.3% (19/30) of ICA patients, and signals in these patients showed higher amplitude in the N1 ((-10.33±6.93) μV vs (-5.11±2.71) μV, t=-10.113, P<0.01) and P2 ((+17.25±8.51) μV vs (+7.31±3.46) μV, t=5.443, P<0.01) waves than that of the controls. Olfactory bulbs were aplastic in 80.0% (24/30) of patients and hypoplastic in 20.0% (6/30) of patients. Fifty-six point seven percent (17/30) of patients had bilateral olfactory sulcus deletion while 43.3% (13/30) had dysplasia, and all of the patients exhibited a depth of olfactory sul cus less than 8 mm. Both the structure of olfactory bulbs and olfactory sulcus were not associated with age for ICA patients (r value was -0.174 and 0.325, respectively, all P>0.05). Conclusions: ICA patients show neurophysiologic deficits and some anatomic differences compared with healthy controls. The absence of oERP combining with a depth of olfactory sulcus less than 8 mm is the important indicator for clinical diagnosis of ICA. The structure of olfactory bulb may be a critical factor for clinical classification of ICA. PMID:34010996 | DOI:10.3760/cm a.j.cn115330-20210219-00070 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Successful treatment of hemophagocytic syndrome caused by auricle infection: one case report

xlomafota13 shared this article with you from Inoreader Message: 噬血细胞综合征是由原发或继发性免疫异常导致的过度炎性反应综合征，病情发展快，易误诊及漏诊，致死率较高，主要表现为发热、全血细胞减少、肝功能损害、凝血功能障碍及组织细胞吞噬形态完整的红细胞、白细胞和血小板。本文报道一例成人女性患者中耳炎术后耳廓感染诱发噬血细胞综合征并救治成功的病例，为耳科医生提供临床借鉴和参考。. Hemophagocytic syndrome is an excessive inflammatory response syndrome caused by primary or secondary immune abnormalities. The disease develops rapidly, is easy to be misdiagnosed and missed, and has a high fatality rate. It mainly manifests as fever, pancytopenia, liver damage, Blood coagulation dysfunction and tissue cells phagocytize red blood cells, white blood cells and platelets with intact morphology. This article reports a case of auricle infection in an adult female patient with otitis media that induced hemophagocytic syndrome and was successfully treated, providing clinical reference and reference for otologists. . Successful treatment of hemophagocytic syndrome caused by auricle infection: one case report Via Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 May 7;56(5):493-495. doi: 10.3760/cma.j.cn115330-20200602-00466. NO ABSTRACT PMID:34011004 | DOI:10.3760/cma.j.cn115330-20200602-00466 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Open Approaches to Stensen Duct Scar

xlomafota13 shared this article with you from Inoreader Open Approaches to Stensen Duct Scar Via Otolaryngologic Clinics of North America Duct scar in the form of stenoses or stricture is the second leading cause of obstructive sialadenitis after stone. Over the past decade, there has been a growing experience demonstrating the effectiveness of endoscopic techniques in the minimally invasive management of salivary duct stenosis. Less information, however, is available with regard to open approaches for recurrent or complex ductal stenoses. This article reports on a case of gland preservation using an open ductal technique that originally was applied in cases of traumatic Stensen's duct injury. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The Evaluation and Management of Carcinoma of the Minor Salivary Glands

xlomafota13 shared this article with you from Inoreader The Evaluation and Management of Carcinoma of the Minor Salivary Glands Via Otolaryngologic Clinics of North America There are several hundred minor salivary glands throughout the upper aerodigestive tract, aiding in lubrication and protection of the system. Compared with all tumors of the head and neck and those of the six major glands, neoplasms of the minor glands are rare. However, more than half are found to be malignant, prompting a low threshold for further work-up. This review discusses the evaluation of patients who present with masses of the minor salivary glands, including strategies for tissue diagnosis and staging. Management options for and long-term survival outcomes of the most common malignancies affecting these glands are also discussed. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Indications for Facial Nerve Monitoring During Parotidectomy

xlomafota13 shared this article with you from Inoreader Indications for Facial Nerve Monitoring During Parotidectomy Via Otolaryngologic Clinics of North America Facial nerve injury is the most feared complication during parotid surgery. Intraoperative electromyographic nerve monitoring can be used to identify the facial nerve, map its course, identify surgical maneuvers detrimental to the nerve, and provide prognostic information. Data regarding outcomes with facial nerve monitoring are heterogeneous. In contrast, the incidence of permanent weakness has not been shown to be significantly affected by use of nerve monitoring. For revision surgery, studies show that monitored patients had (1) weakness that was less severe with quicker recovery and (2) shorter operative times compared with unmonitored patients. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Transoral Excision of Parapharyngeal Space Tumors

xlomafota13 shared this article with you from Inoreader Transoral Excision of Parapharyngeal Space Tumors Via Otolaryngologic Clinics of North America Transoral excision of parapharyngeal space (PPS) tumors has increased in popularity along with the increased use of robotic and endoscopic surgical technology. Here, the authors highlight the indications, techniques, outcomes, and complications of transoral approaches to PPS tumors, with a special emphasis on salivary tumors of the PPS and the transoral robotic surgery approach. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Incorporating Sialendoscopy into the Otolaryngology Clinic

xlomafota13 shared this article with you from Inoreader Incorporating Sialendoscopy into the Otolaryngology Clinic Via Otolaryngologic Clinics of North America Simple sialendoscopy procedures may be performed in the outpatient clinic with few complications. This process spares patients the risks, increased cost, and time burdens of sialendoscopy under general anesthesia. Sialendoscopy procedures may be incorporated into the outpatient practice after gaining experience with these procedures in the operating room. Diagnostic sialendoscopy, dilation of stenosis, and endoscopic sialolithotomies of small, freely mobile stones are appropriate for in-office sialendoscopy in many instances. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Management of Mucoceles, Sialoceles, and Ranulas

xlomafota13 shared this article with you from Inoreader Management of Mucoceles, Sialoceles, and Ranulas Via Otolaryngologic Clinics of North America Mucoceles are common salivary gland disorders. Mucoceles are benign, mucus-filled extravasation pseudocysts that commonly arise on the lower lip of children and young adults. Although surgical excision is commonly performed to remove these lesions, other treatments include marsupialization, micromarsupialization laser ablation, cryotherapy, intralesional steroid injection, and sclerosing agents. Traumatic sialoceles commonly arise from injury to the parotid duct. Treatment of sialoceles from acute parotid duct injury and for delayed presentations after injury are discussed. Ranulas are a subtype of mucocele from the sublingual gland classified as superficial or plunging. Treatment of ranulas must address the sublingual gland. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Management Options for Sialadenosis

xlomafota13 shared this article with you from Inoreader Management Options for Sialadenosis Via Otolaryngologic Clinics of North America Sialadenosis (sialosis) is a chronic, noninflammatory, nonneoplastic, bilateral, often painless enlargement of the salivary glands, most frequently affecting the parotid glands. Approximately 50% of cases are associated with an underlying disease process. The pathogenesis of sialadenosis is unknown but likely results from an autonomic neuropathy. The key to management is diagnosis and management of any poorly controlled underlying medical process. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Soft Tissue Reconstruction of Parotidectomy Defect

xlomafota13 shared this article with you from Inoreader Soft Tissue Reconstruction of Parotidectomy Defect Via Otolaryngologic Clinics of North America This article provides a review of soft tissue reconstructive options for the parotidectomy defect, including skin incision, primary closure, acellular dermis, autologous fat transfer, local and regional flaps, and free tissue transfer. The authors discuss considerations for volume enhancement, skin coverage, prevention of Frey syndrome, tumor surveillance, and potential complications. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Transoral Sialolithotomy Without Endoscopes

xlomafota13 shared this article with you from Inoreader Transoral Sialolithotomy Without Endoscopes Via Otolaryngologic Clinics of North America Sialoendoscopy is a valuable technique for a variety of obstructive and nonobstructive disorders of the major salivary glands. However, the utility of sialoscopes is limited for salivary stones, which frequently required open removal. Transoral sialolithotomy without scopes is an efficient, low-cost alternative with excellent outcomes available for most of the submandibular stones. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

IgG4-Related Disease and the Salivary Glands

xlomafota13 shared this article with you from Inoreader IgG4-Related Disease and the Salivary Glands Via Otolaryngologic Clinics of North America IgG4-related disease is a rare, immune-mediated, systemic disease that is characterized by soft tissue lymphocyte infiltration and resultant fibrosis. The salivary glands are among the most commonly affected organs. Patients present with subacute submandibular and/or parotid swelling and sialadenitis. Diagnosis incorporates clinical, serologic, radiologic, and pathologic findings. Most cases respond quickly to systemic glucocorticoids. IgG4-related disease mimics many infectious, inflammatory, and neoplastic diseases. Therefore, IgG4-related disease is frequently misdiagnosed. A knowledge of the pathophysiology, diagnosis, and management of IgG4-related disease is important for providers who treat salivary gland diseases. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Extent and Indications for Elective and Therapeutic Neck Dissection for Salivary Carcinoma

xlomafota13 shared this article with you from Inoreader Extent and Indications for Elective and Therapeutic Neck Dissection for Salivary Carcinoma Via Otolaryngologic Clinics of North America Although salivary gland malignancies account for only a small percentage of all head and neck cancers, the incidence is increasing. Furthermore, there is a wide variety of histologic subtypes which must be taken into account in the context of their location. Each is associated with a different rate of regional metastasis and overall survival. This article examines the incidence of salivary gland malignancies and provides evidence for the indications for and extent of elective or therapeutic neck dissection based on location, pathologic type, and histopathologic characteristics. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.