Clinical Thyroidology®for the Public – Highlighted Article

From Clinical Thyroidology^® for the Public: Treatment-free survival, which is living without the need for treatment for recurrent cancer, is an important outcome for thyroid cancer patients. The goal of this study was to understand factors associated with treatment-free survival in the general population, because this will enable the care teams to tailor long term follow up to a particular situation, and, many times, help decrease patient worry. Read More…

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Is skip metastases associated with tumor thickness and tumor size in tongue carcinoma patients?

Abstract

Objective

To assess the correlation of skip metastases associated with increase in tumor thickness and size of the tumor.

Material and methods

A retrospective analysis was carried out from August 2009 to August 2015. In this study, a total number of 33 carcinoma tongue patients having T1, T2, and T3 sizes with N0 and N+ clinical necks who were treated by supraomohyoid neck dissection, extended supraomohyoid neck dissection, and modified radical neck dissection were analyzed. The data was assessed using Shapiro-Wilk W test, Nagelkerke R² regression model, mean, and standard deviation.

Results

Metastasis to lymph nodes was present in 75% of patients. Level I and level II were the commonest sites to be involved, i.e., 20 patients. Three patients had skip metastasis out of which two patients had metastasis at level III (6%), and one patient had skip metastasis at level IV (3%).

Conclusion

The incidence of skip metastasis increases with tumor thickness and tumor size in tongue carcinoma patients.

Clinical relevance

The article reveals the positive relationship between tumor thickness, tumor size, and skip metastasis. The analysis shows tumor thickness as a higher predictor for skip metastasis with odds ratio of 5.5 compared to the tumor size having odd ratio 2.

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Changes in Serum Immunoglobulin G4 Levels in Patients with Newly Diagnosed Graves’ Disease

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0669-9333

Objective Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is an immune-mediated condition that can affect almost any organ. We investigated the association between IgG4-RD and the main characteristics of Graves' disease (GD) at the time of diagnosis. Additionally, we evaluated whether serum IgG4 levels change during treatment. Design and patients Twenty-eight patients with newly diagnosed GD were enrolled into this longitudinal follow-up study. Serum IgG4 levels and thyroid function were measured in all the participants at the time of diagnosis. Further, the serum IgG4 levels of nine of 28 patients with untreated GD were measured after the achievement of euthyroid state (through the use of methimazole). Results Two (7.1%) of 28 patients with untreated GD had elevated serum IgG4 levels of >135 mg/dL. There was no significant difference in the average IgG4 levels before and after the achievement of euthyroid state (66.2±74.0 mg/dL vs. 50.5±47.3 mg/dL). In two patients, the elevated serum IgG4 levels returned to normal after treatment. However, one patient had an elevated serum IgG4 level of 136.6 mg/dL after treatment. Conclusions This study showed that serum IgG4 levels varied with treatment in patients with GD, independent of thyroid function, suggesting that IgG4 might be indirectly related to GD.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
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Altered TEG Parameters Identify Hypercoagulablilty and are of Diagnosis Value for Papillary Thyroid Carcinoma Patients

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0723-3295

Objective The goal of this study was to clarify the changes and clinical significance of thromboelastography (TEG) parameters in papillary thyroid carcinomas and nodular goiters. Methods 62 nodular goiter (NG) patients and 53 papillary thyroid carcinoma (PTC) patients were included. Coagulation indicators, together with a series of TEG parameters were collected and analyzed, compared with results of 61 healthy controls (HC). Correlation analysis was conducted between routine coagulation indicators and TEG parameters. ROC curves were used to evaluate the potential diagnosis value of the TEG parameters that were altered in papillary thyroid carcinoma patients. Results APTT and PT in papillary thyroid carcinoma group were statistically significant higher than that in control group (p<0.05). MPV was found to be higher in PTC than NG and healthy controls.R, K and SP levels were significantly lower in PTC group than that in HC group; Angle, CI and TPI levels were significantly higher in PTC group than that in HC group. Areas under the ROC curve of CI, TPI, and angle were 0.725, 0.714, and 0.687 for distinguishing PTC from HC, 0.662, 0.668 and 0.591 for distinguishing PTC from NG. Conclusion TEG parameters are altered and indicate hypercoagulablilty status of papillary thyroid carcinoma patients; CI, TPI, and angle could be potential diagnosis indicators for detecting papillary thyroid carcinoma.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
Table of contents  |  Abstract  |  Full text

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Changes in Oxidized Low-Density Lipoprotein Rather Than in Paraoxonase1 are Associated with Changes in the Leptin/Leptin Receptor Ratio in Obese Children During Weight-Loss Therapy

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0723-3951

Background Oxidative stress and impaired production of adipokines in childhood obesity contribute to the development of obesity-related disorders. We assessed whether weight loss after lifestyle intervention alters biomarkers of oxidant/antioxidant status, and whether these alterations are associated with changes in anthropometric parameters and adipokines in obese children. Materials and Methods We determined oxidized low-density lipoprotein (ox-LDL), anti ox-LDL, paraoxonase1 (PON1), leptin, soluble leptin receptor (sOB-R), total adiponectin, high molecular weight adiponectin concentrations and body composition (by dual-energy X-ray absorptiometry) in 60 prepubertal obese children (Body Mass Index, BMI Z-score>2) before and after a 3-month intervention. The control group consisted of 44 non-obese children (BMI Z-score<−1+1>). Results Ox-LDL, ox-LDL/LDL, and anti ox-LDL concentrations as well as leptin to sOb-R ratio were reduced (p<0.001; p=0.018; p<0.001; p<0.001, respectively) in obese children with weight loss (BMI Z-score change≤−0.5) after a 3-month therapy. These parameters were stable in the obese group without weight loss (BMI Z-score change>−0.5). Changes in ox-LDL and PON1 levels in all obese children correlated positively with changes in the leptin to sOB-R ratio (r=0.400, p=0.002; r=0.304, p=0.028, respectively). After adjustment for changes in BMI Z-score in the multivariate regression model, the association between the changes in ox-LDL levels and changes in the leptin/sOb-R ratio remained statistically significant (β=0.184, p=0.014). Conclusions We found out that a 3-month lifestyle intervention associated with weight loss improves the oxidant/antioxidant balance and promotes anti-atherogenic changes in prepubertal obese children in a way dependent on the alterations in the leptin to sOB-R ratio.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
Table of contents  |  Abstract  |  Full text

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Lipid Level Related with Osteoporosis in Type 2 Diabetes Patients

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0735-9361

Objective Osteoporosis is a systemic skeletal disorder characterizedby reduced bone mass, deteriorated bone structure. Various studies have tried to evaluate the association between lipid level and osteoporosis, but the results were proved to be controversial. The objectives of this study are to assess the correlation between BMD and serum lipid levels, to determine independent variables associated with osteoporosis and osteopenia in men and postmenopausal women with type 2 diabetes (T2D). Materials and methods All participants of the study were carried out biochemical analysis of blood and the analysis of the lipid profile that included total cholesterol (TC) and triglyceride (TG). Physical examination and dual-energy X-ray absorptiometry examination were performed. Multiple linear regression and multivariate logistic regression were used to evaluate associations between serum TC and TG levels and the osteoporosis or osteopenia. Results The level of serum TG was directly correlated with BMD at the lumbar spine in all patients in multiple linear regression models. After adjusting for potential confounding factors, decreased level of serum TG was independent risk factor for osteoporosis(p=0.022) in T2D patients. It also showed that a greater BMI was protective factor for osteoporosis (p=0.019) and lower level of β-CTX was an independent risk factor for osteopenia (p=0.008) and osteoporosis (p=0.001) in T2D patients. Conclusion Among Chinese patients with type 2 diabetes, the decreased level of serum TG might indicate a risk of osteoporosis. Further research is needed to confirm the finding and to clarify the contradictions identified.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
Table of contents  |  Abstract  |  Full text

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Metastatic Phaeochromocytoma: Spinning Towards More Promising Treatment Options

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0715-1888

Phaeochromocytomas (PCC) and paragangliomas (PGL) are rare tumours arising from the chromaffin cells of the adrenal medulla (PCC) or the paraganglia located outside the adrenal gland (PGL). However, their incidence is likely to be underestimated; around 10% of all PCC/PGL are metastatic, with higher metastatic potential of PGLs compared to PCCs. If benign, surgery is the treatment of choice, but if metastatic, therapy is challenging. Here we review the currently existing therapy options for metastatic PCCs/PGLs including conventional chemotherapy (the original Averbuch scheme, but updated), radiopharmaceutical treatments (131I-MIBG, 90Y- and 177Lu-DOTATATE) and novel targeted therapies (anti-angiogenic tyrosine kinase inhibitors and mTORC1 inhibitors), emphasising future therapeutic approaches (HIF-2α and PARP inhibitors, temozolomide alone, metronomic temozolomide, somatostatin analogues) based on the oncogenic signalling pathways related to three different clusters comprising more than 20 well-characterised PCC/PGL susceptibility genes. We suggest that targeted combination therapies including repurposed agents may offer more effective future options worthy of exploration.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
Table of contents  |  Abstract  |  Full text

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Clinically Relevant Prognostic Parameters in Differentiated Thyroid Carcinoma

Abstract

Although differentiated thyroid carcinomas typically pursue an indolent clinical course, it is important to identify the subset of tumors that are most likely to behave aggressively so that patients with these tumors are counseled and treated appropriately. Extent of disease is fundamental to the prognostication for differentiated thyroid carcinoma; however, there are additional histologic features of the tumor separate from extent of disease that have been shown to affect clinical course. This review will start with a discussion of aggressive variants of papillary thyroid carcinoma, move to the prognostic significance of vascular invasion in follicular thyroid carcinoma, and finish with a discussion of Hürthle cell carcinoma, with an emphasis on why it is not considered a subtype of follicular thyroid carcinoma in the 2017 WHO Classification of Tumors of Endocrine Organs.

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Thyroid® High-Impact Articles

FREE ACCESS through October 2, 2018.

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Latest Impact Factor: 7.557
The Official Journal of: American Thyroid Association^®

Impact of Hypothyroidism and Heart Failure on Hospitalization Risk
Kevin Ro, Alexander D. Yuen, Lin Du, Clarissa C. Ro, Christian Seger, Michael W. Yeh, Angela M. Leung, and Connie M. Rhee

Subclinical Hypothyroidism and the Risk of Cardiovascular Disease and All-Cause Mortality: A Meta-Analysis of Prospective Cohort Studies
Shinje Moon, Min Joo Kim, Jae Myung Yu, Hyung Joon Yoo, and Young Joo Park 

Cardiovascular Morbidity and Mortality After Treatment of Hyperthyroidism with Either Radioactive Iodine or Thyroidectomy
Ryödi Essi, Metso Saara, Huhtala Heini, Välimäki Matti, Auvinen Anssi, and Jaatinen Pia 

Decreasing Disease-Specific Mortality of Differentiated Thyroid Cancer in Korea: A Multicenter Cohort Study
Min Ji Jeon, Hee Kyung Kim, Eun Heui Kim, Eun Sook Kim, Hyon-Seung Yi, Tae Yong Kim, Ho-Cheol Kang, Young Kee Shong, Won Bae Kim, Bo Hyun Kim, and Won Gu Kim  

Incidence and Survival of Thyroid Cancer in Children, Adolescents, and Young Adults in Denmark: A Nationwide Study from 1980 to 2014
Jakob Schmidt Jensen, Christian Grønhøj, Christian Mirian, David Hebbelstrup Jensen, Jeppe Friborg, Christoffer Holst Hahn, Tina Klitmøller Agander, and Thomas Hjuler 

Sonographically Estimated Risks of Malignancy for Thyroid Nodules Computed with Five Standard Classification Systems: Changes over Time and Their Relation to Malignancy
Giorgio Grani, Livia Lamartina, Marco Biffoni, Laura Giacomelli, Marianna Maranghi, Rosa Falcone, Valeria Ramundo, Vito Cantisani, Sebastiano Filetti, and Cosimo Durante 

Sobetirome and its Amide Prodrug Sob-AM2 Exert Thyromimetic Actions in Mct8-Deficient Brain
Soledad Bárez-López, Meredith D. Hartley, Carmen Grijota-Martínez, Thomas S. Scanlan, and Ana Guadaño-Ferraz  

The post <i>Thyroid^®</i> High-Impact Articles appeared first on American Thyroid Association.

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The dynamic-lymphaticovenular anastomosis method for breast cancer treatment-related lymphedema: creation of functional lymphaticovenular anastomoses with use of preoperative dynamic ultrasonography

Lymphaticovenular anastomosis (LVA) is generally effective for breast cancer treatment-related upper extremity lymphedema (UEL). Clinical improvement is, however, limited by the degree of sclerosis of the lymphatic vessels. We have developed a method by which we use dynamic ultrasonography to depict vessels through which lymph can be propelled into the LVA under the power of the patient's natural hand movements.

https://ift.tt/2NtYeZq

Adipose-derived regenerative cells and fat grafting for treating breast cancer-related lymphedema: Lymphoscintigraphic evaluation with one year follow-up

Background: Breast cancer-related lymphedema (BCRL) is a feared late complication. Present treatment options are lacking. Recent studies have suggested that mesenchymal stromal cells can alleviate lymphedema. Herein, we report the results from the first human pilot study with adipose-derived regenerative cells (ADRC) for treating BCRL with one year follow-up. Material and methods: We included ten BCRL patients. ADRCs were injected directly into the axillary region together with a scar releasing fat graft procedure.

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Outcomes of shoulder abduction after nerve surgery in patients over 50 following traumatic brachial plexus injury

There is controversy regarding the effectiveness of brachial plexus reconstruction in older patients as it is felt that outcomes are poor. The aim of this study is to determine the outcomes of shoulder abduction obtained after nerve reconstruction in patients over the age of 50 and factors related to success.

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Use of a perforator/subcutaneous pedicled propeller flap for reconstruction of lower eyelid defects

Full thickness skin grafts (FTSGs) and flaps from the upper eyelid or cheek can be used for reconstruction of lower eyelid defects, including the anterior lamella. However, the upper eyelid has a limited and insufficient amount of skin, while cheek flaps have a restricted arch of rotation. Here we report the procedure and outcomes of a perforator/subcutaneous pedicled propeller flap for reconstruction of lower eyelid defects including the anterior lamella.A retrospective study of 12 patients who underwent treatment for eyelid anterior lamella defects with perforator/subcutaneous pedicled propeller flaps was conducted between March 2015 and June 2017.

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Predictors of complications following breast reduction surgery: A national surgical quality improvement program study of 16812 cases.

Breast reduction is one of the most common procedures performed by plastic surgeons. Despite good outcomes and high patient satisfaction, there is little national data examining the predictors leading to complications in this patient population. We accessed a national outcomes database to examine these factors.

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Scholar : intitle:laryngeal - new results

[HTML] A systematic approach to the recurrent laryngeal nerve dissection at the cricothyroid junction

O Butskiy, BA Chang, K Luu, RM McKenzie… - Journal of Otolaryngology …, 2018

To describe and evaluate a four step systematic approach to dissecting the recurrent
laryngeal nerve (RLN) starting at the cricothyroid junction during thyroid surgery
(subsequently referred to as the retrograde medial approach). All thyroidectomies …

PS01. 223:'ENERGY-LESS TECHNIQUE'WITH MINI-CLIPS FOR RECURRENT LARYNGEAL NERVE LYMPH NODE DISSECTION IN PRONE THORACOSCOPIC …

H Saeki, Y Nakashima, N Kubo, K Hirose, S Sasaki… - Diseases of the Esophagus, 2018

Background Esophagectomy with radical mediastinal lymph node dissection remains
the standard option for the curative treatment of esophageal squamous cell
carcinoma. However, meticulous lymph node dissection along the recurrent …

A Comparison of Laboratory and Virtual Laryngeal Dissection Experiences on Preservice Music Educators' Knowledge and Perceptions

MC Brunkan, EM Mercado - Journal of Voice, 2018

Science-education literature is replete with studies examining how students learn
anatomy most effectively and efficiently. Some researchers have found that students
learn best through hands-on learning, whereas other investigators have concluded …

 

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Scholar : ΣΤΟΜΑΤΙΤΙΣ - νέα αποτελέσματ

57TiP "PRIME Study: Searching for immune biomarkers in advanced castration resistant prostate cancer (CRPC) patients treated with standard therapy

N Romero-Laorden, A Zapatero, L San Jose… - Annals of Oncology, 2018

… In both p16 positive and negative stomatitis (p ¼ 0.75) was the most common adverse
event. Oral stomatitis of Grade 1&2 (100% in p16 þve and 96.8% in p16 -ve patients)
and grade 3&4 (58.8% in p16þ and 49.20% in p16_ patients) …

56PQuantification BCL6 tissue expression using FISH and immunohistochemistry in diffuse large B-cell lymphoma by digital image analysis

V Kushnarev, N Matyashina - Annals of Oncology, 2018

… In both p16 positive and negative stomatitis (p ¼ 0.75) was the most common adverse
event. Oral stomatitis of Grade 1&2 (100% in p16 þve and 96.8% in p16 -ve patients)
and grade 3&4 (58.8% in p16þ and 49.20% in p16_ patients) …

54PImpact of HPV DNA and p16 on radical chemo-radiotherapy response in oropharyngeal cancer patients

P Yadav, N Kumar, S Beniwal - Annals of Oncology, 2018

… In both p16 positive and negative stomatitis (p = 0.75) was the most common adverse
event. Oral stomatitis of Grade 1&2 (100% in p16 +ve and 96.8% in p16 -ve patients)
and grade 3&4 (58.8% in p16+ and 49.20% in p16_ patients) …

55PTP53 mutations as predictor of response and longer survival under immune checkpoint inhibitors in advanced non-small cell lung cancer

S Assoun, N Theou-Anton, M Nguenang, A Cazes… - Annals of Oncology, 2018

… In both p16 positive and negative stomatitis (p ¼ 0.75) was the most common adverse
event. Oral stomatitis of Grade 1&2 (100% in p16 þve and 96.8% in p16 -ve patients)
and grade 3&4 (58.8% in p16þ and 49.20% in p16_ patients) …

[PDF] Effect of Herbal Echinacea on Recurrent Minor Oral Aphthous Ulcer

F Khozeimeh, Z Saberi, A Tavangar, FF Badi - The Open Dentistry Journal, 2018

… Practical aspects of management of recurrent aphthous stomatitis. J …
[https://ift.tt/2OGURv5] [PMID: 17714120]
[3] Hudson J. Recurrent aphthous stomatitis: Diagnosis and management …

Mannoside Glycolipid Conjugates Display Antiviral Activity Against Ebola Virus

O Reynard, E Schaeffer, VA Volchkova, A Cimarelli… - The Journal of Infectious …, 2018

… Experiments using live EBOV were performed in the Jean Merieux biosafety level
4 INSERM laboratory (Lyon, France). Generation of vesicular stomatitis virus (VSV)
replicon pseudo- types have been described previously [15] …

[HTML] Molecular Discrimination of the Candida parapsilosis Species Complex via SADH Gene Analysis and Evaluation of Proteinase Activity Among the Isolates

K Pakshir, F Karimi, K Zomorodian, S Ansari, H Nouraei… - Jundishapur Journal of …, 2018

… Extracellular aspartyl proteinase (Sap) is a putative virulence factor in Candida
species (8). In our previous study, Candida species were isolated from onychomycosis
and oral lesions of diabetic and denture stomatitis patients …

53PmiR-4317, a promising player tuning the anti-tumor armamentarium against breast cancer

RA Youness, RA Assal, A Abdelmotaal, MZ Gad - Annals of Oncology, 2018

… In both p16 positive and negative stomatitis (p = 0.75) was the most common adverse
event. Oral stomatitis of Grade 1&2 (100% in p16 +ve and 96.8% in p16 -ve patients)
and grade 3&4 (58.8% in p16+ and 49.20% in p16_ patients) …

Buparlisib plus fulvestrant versus placebo plus fulvestrant for postmenopausal, hormone receptor-positive, human epidermal growth factor receptor 2-negative …

M Campone, SA Im, H Iwata, M Clemons, Y Ito… - European Journal of Cancer, 2018

… for hyperglycemia (43% versus 8%), elevated ALT (40% versus 7%), nausea
(40% versus 24%), elevated AST (38% versus 10%), diarrhoea (35% versus
15%), fatigue (33% versus 25%), rash (33% versus 7%), decreased appetite …

Interdisziplinäre Therapie von Knochenmetastasen

J Fakler, T Todenhöfer, M Müller, AA Kurth… - Fortbildung Osteologie 4, 2018

… senken konnte (Gnant et al. 2013). Die häufigste Nebenwirkung von Everolimus
ist eine Stomatitis (40%). Das Risiko einer Pneumonitis wird mit 8% angegeben
(Motzer et al. 2008). Ende 2013 wurde das Radiopharmakon …

 

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Scholar : CPAP - νέα αποτελέσματα

[PDF] Beneficial Effects of CPAP Treatment in High-risk Subgroups of OSA Patients: Some Evidence, at Last

MR Bonsignore - EClinicalMedicine, 2018

In the last three decades, several studies underlined the clinical and
pathophysiological links between obstructive sleep apnea (OSA) and cardiovascular
risk [1]. Clinically, OSA patients are generally obese, often affected by systemic …

[PDF] Side effects of mandibular advancement splints for the treatment of snoring and obstructive sleep apnea: a systematic review

OFM Martins, CMC Junior, RRP Rossi, PA Cunali… - 2018

… bed partner-friendly, less invasive, tolerable, and efficacious choice for snoring
and mild-to-moderate obstructive sleep ap- nea (OSA).1 The current literature
increasingly sup- ports MAS as an effective alternative to Continuous Positive …

New steps forward for obstructive sleep apnoea in the era of precision medicine

Y Peker, PJ Strollo - 2018

Is Tongue-Lip Adhesion or Mandibular Distraction More Effective in Relieving Obstructive Apnea in Infants with Robin Sequence?

CM Resnick, CE Calabrese, R Sahdev, BL Padwa - Journal of Oral and Maxillofacial …, 2018

… failure-to-thrive, cardiopulmonary arrest, and death 1, 2, 3, 4, 5, 6, 7, 8.
Non-operative interventions including side or prone positioning, insertion
of a nasopharyngeal airway, placement of an oral appliance 9, 10, and …

Opioid-free total intravenous anesthesia with ketamine as part of an enhanced recovery protocol for bariatric surgery patients with sleep disordered breathing

J Aronsohn, G Orner, G Palleschi, M Gerasimov - Journal of clinical anesthesia, 2019

… effects. Written consent was obtained for this report. A 40 year-old morbidly obese
(BMI 50.1 kg·m −2 ) female with history of severe OSA non-compliant with home CPAP
presented for laparoscopic vertical sleeve gastrectomy. To …

Weight‐Related Terms Differentially Affect Self‐Efficacy and Perception of Obesity

CM Hopkins, GG Bennett - Obesity, 2018

… Hypothyroidism (or medication), 34 (7.8). Use of CPAP machine, 8 (1.8).
Heart attack, 5 (1.1) … Specialist visits, 1.01 (3.15). a CPAP, Continuous positive
airway pressure; ER, emergency room; GED, general equivalency diploma; …

Comparison of Early Nasal Intermittent Positive Pressure Ventilation and Nasal Continuous Positive Airway Pressure in Preterm Infants with Respiratory Distress …

M Dursun, S Uslu, A Bulbul, M Celik, U Zubarioglu… - Journal of Tropical …, 2018

AbstractAims. To compare the effect of early nasal intermittent positive pressure ventilation
(nIPPV) and nasal continuous positive airway pressure (nCPAP) in.

Positive Pressure Ventilation in the Cardiac Intensive Care Unit

CL Alviar, PE Miller, D McAreavey, JN Katz, B Lee… - Journal of the American …, 2018

Maschinelle Beatmung und Narkose

U Morgenstern, O Simanski - Medizinische Physik, 2018

… weaning ). Eine Arbeitspunktanhebung über einen gegenüber dem Umgebungsdruck
erhöhten Druck durch PEEP oder CPAP/BiPAP (Continuous/Biphasic Positive Airway
Pressure ) verhindert einen Alveolenkollaps. Regel …

[HTML] What Can Urine Tell Us About Medication Adherence?

PL Anderson - EClinicalMedicine, 2018

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