Optimization in the performance and emission parameters of a DI diesel engine fuelled with pentanol added Calophyllum inophyllum /diesel blends using response surface methodology

Abstract

The primary objective of this work was to enhance the performance and emission of the computerized variable compression ratio (VCR) diesel engine fuelled with pentanol/Calophyllum inophyllum (CI)/diesel fuel blends. Based on the prerequisite for the current research, response surface methodology (RSM), an optimization technique, was adopted for the process parameters compression ratio (CR), load and fuel blends, and the optimized responses like brake thermal efficiency (BTE), brake specific fuel consumption (BSFC), oxides of nitrogen (NO_x), carbon monoxide (CO), carbon dioxide (CO₂), hydrocarbon (HC), and smoke were revealed with the help of Derringer's desirability approach. From the results, it is notified that pentanol-fuelled engine showed better performance and emissions at 17.5 CR, P20C20 (pentanol 20%+Calophyllum inophyllum 20%+diesel 60%) blend and 2.5 bmep (brake mean effective pressure) load conditions. The observed mathematical models and validation experiments show that the VCR diesel engine exhibits maximum efficiency and minimum emissions at the optimized input parameters.

https://ift.tt/2ODAE8H

Comparison of long-pulsed Nd: YAG laser with cryotherapy in treatment of acral warts

Abstract

Acral warts are considered as prevalent reasons for dermatologic consultations and remain an important continuing challenge until now because there is no consensus about optimal therapeutic modality. This study investigated the efficacy of long-pulsed Nd: YAG laser therapy and cryotherapy in treatment of acral warts. Patients who underwent treatment with cryotherapy or long-pulsed Nd: YAG laser therapy for symmetrical and bilateral warts on the extremities (hand and foot) that is confirmed by an expert dermatologist from May 2016 until March 2018 were assessed for enrollment in our study. Laser and cryotherapy sessions were applied every 2 weeks for a maximum of six sessions. Patients followed up and evaluated 3 months after the last treatment. Data were analyzed by SPSS (v.21. IBM Inc. IL). The P value less than 0.05 was considered significant. From 60 enrolled patients, 134 lesions were treated using cryotherapy and 114 other lesions treated with laser beam. Thirty-four males (average age 26.85 ± 7.528 years) and 26 females (average age 26.73 ± 5.640 years) participated. Finally, it was a significant reduction in both lesion width (P = 0.000) and length (P = 0.000) after the sessions of cryotherapy. The width and length of lesions is reduced significantly after each session of laser therapy similarly (P = 0.000). Cryotherapy and long-pulsed Nd: YAG laser are effective on the reduction of both width and length of lesions. Clinically, the methods are not different in their ultimate effects.

https://ift.tt/2MkNHyH

Soft-Tissue Infection Caused by Streptococcus anginosus After Intramucosal Hyaluronidase Injection: A Rare Complication Related to Dermal Filler Injection

No abstract available

https://ift.tt/2OE6Wki

Association between alcohol dependence and both periodontal disease and tooth loss: a cross-sectional study

Abstract

The impact of alcohol consumption on periodontal disease and tooth loss is still under debate. The aim of this cross-sectional study was to evaluate the association between alcohol dependence and both periodontal diseases and tooth loss in Brazilian native Indians. Full mouth periodontal examination was performed and tooth loss was clinically evaluated in a representative sample of 225 Indians (≥ 19 years). Sociodemographic, oral health-related data, and alcohol dependence were evaluated using structured questionnaires. The subjects were categorized as either alcohol-dependent or non-dependent according to the Alcohol Use Disorders Identification Test results. Severe periodontal disease was defined in individuals with ≥ 2 proximal sites with a clinical attachment level ≥ 6 mm, not on the same tooth, and ≥ 1 proximal site with a probing depth ≥ 5 mm. Tooth loss was categorized as one or more missing teeth, or no missing teeth. Bivariate models followed by logistic regression were used to assess the association between alcohol dependence and both periodontal disease and tooth loss. Prevalence ratio (PR) was calculated using Mantel-Haenszel analysis. Alcohol dependence increased 2.5 times the risk for tooth loss (prevalence ratio [PR] =2.49, 95% confidence interval [CI] = 1.01–9.04, p = 0.05). Severe periodontal disease was not associated with alcohol dependence (OR = 0.54, 95% CI = 0.22–1.31, p = 0.23). In conclusion, alcohol dependence was associated with tooth loss in the present population, but severe periodontal disease was not. Questions on alcohol dependence should be included in dental anamnesis questionnaires, and patients diagnosed with alcohol dependence should be referred for dental evaluation.

https://ift.tt/2MqV2g5

The effect of high temperature environment on rock properties—an example of electromagnetic radiation characterization

Abstract

High temperature causes thermal damage to rock; the macrofracture and microfracture of rock can be produced under the action of temperature treatment. Under the influence of high temperature, the surrounding rock of deep underground engineering will suffer instability damage and cause serious harm to the people. In order to use the electromagnetic radiation (EMR) technology (a non-contact geophysical method) for evaluating the thermal stability of rock in underground thermal engineering applications, we established the EMR testing experimental system of rock under the action of a continuous heat source. The variation of EMR signals of rock under different temperatures was tested, and the EMR signals generates during the process of rock thermal deformation and thermal fracture, which were later analyzed. Under the action of a continuous heat source, the rock materials produced EMR signals with three kinds of frequencies. With the increase of rock temperature, the variation trends of EMR signals varied from the slow growth rate to the rapid growth rate, EMR signals can be divided into five stages. The increase of EMR signals is positively correlated with temperature, the Hurst exponent was higher than 0.7. The thermal stress was responsible for thermal deformation and fracture, thus generating the EMR signals. The research results have important guiding significance for the application of EMR technology to the evaluation of rock thermal stability.

https://ift.tt/2OCyTJ4

Nitrogen leaching losses following biogas slurry irrigation to purple soil of the Three Gorges Reservoir Area

Abstract

Ammonium (NH₄⁺) in biogas slurries is readily nitrified into very mobile soil nitrate (NO₃⁻) to promote nitrogen (N) leaching concerning which a few studies, however, have been reported. These slurries are regularly applied through irrigation to purple soil in the Three Gorges Reservoir Area, and therefore we explored the consequent N leaching there with a plot experiment. Biogas slurry irrigation was carried out with nitrogen application rates of 0, 48, 144, 240, 336, and 480 kg N/ha. As a result, the last two rates have triggered N leaching being detrimental to groundwater safety. In addition, N leaching was negatively correlated with soil microbial biomass, diversity, and respiration, indicating a potential technique to prevent it with soil heterotrophs activated by increased ratios of carbon to nitrogen (C/N) in biogas slurries.

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Graphical Abstracts

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Obituary: A Legend in Neuroscience (1948-2018) Dr. Stephen D. Skaper, Ph. D

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Dedication: Commendation of Diligence A Legend in Neuroscience (1948-2018) Dr. Stephen D. Skaper, Ph.D

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Dedication: In memory of Prof. Stephen Drake Skaper

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Meet Our Editorial Board Member

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Structure, Function and Interactions of Tau: Particular Focus on Potential Drug Targets for the Treatment of Tauopathies

https://ift.tt/2OAwkXS

Dl-3-n-Butylphthalide (NBP): A Promising Therapeutic Agent for Ischemic Stroke

https://ift.tt/2Mpqhbk

Pain-Related Behavior and Brain Activation in a Cynomolgus Macaque Model of Postoperative Pain

https://ift.tt/2KZ2MRO

Protective Effects of Crocetin on Depression-like Behavior Induced by Immobilization in Rat

https://ift.tt/2MpHvoY

Hydroxysafflor Yellow A Reprograms TLR9 Signalling Pathway in Ischaemic Cortex after Cerebral Ischaemia and Reperfusion

https://ift.tt/2Mx3muU

A Longitudinal Study of Alterations of S100B, sRAGE and Fas Ligand in Association to Olanzapine Medication in a Sample of First Episode Patients with Schizophrenia

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Oleanolic Acid Ameliorates Aβ25-35 Injection-induced Memory Deficit in Alzheimer's Disease Model Rats by Maintaining Synaptic Plasticity

https://ift.tt/2Mtijhe

Are recovery stories helpful for women with eating disorders? A pilot study and commentary on future research

Abstract

Background

Anecdotally it is well known that eating disorder memoirs are popular with people with anorexia nervosa and recovery stories are readily available online. However, no research to date has empirically explored whether such stories are helpful for current sufferers. The aim of the current pilot study was to explore the efficacy of recovery narratives as a means of improving motivation and self-efficacy and to qualitatively explore patient perspectives of such stories.

Method

Fifty-seven women with anorexia nervosa and subclinical anorexia nervosa participated in this online study. Participants were randomised to either receive recovery stories or to a wait-list control group. After completing baseline measures, participants read five stories about recovery, and completed post-intervention measures two weeks later.

Results

The quantitative results indicated that reading stories of recovery had no effect on motivation and self-efficacy over a two-week period. In contrast, the qualitative results showed that the stories generated thoughts about the possibility of recovery and the majority indicated they would recommend them to others.

Conclusions

This study adds to a growing body of research exploring the integration of voices of lived experience into treatment approaches. Future research should focus on 1) identifying for whom and at which stage of illness recovery stories might be helpful; 2) the mechanism via which they might operate; and 3) the most helpful way of presenting such stories.

https://ift.tt/2OCj6tE

Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden

AbstractBackground.The genomic landscape of Hodgkin lymphoma (HL) has been difficult to characterize due to the paucity of neoplastic cells and an abundant microenvironment. Such characterization is needed in order to improve treatment strategies.Materials and Methods.We performed comprehensive genomic profiling (CGP) using targeted next‐generation sequencing on archival formalin‐fixed paraffin embedded tumor samples from 63 patients to analyze the landscape of HL.Results.CGP was successful for 49/63 archival specimens (78%), and revealed aberrations impacting genes including B2M, TP53, and XPO1 (E571). Of the 34 patients for whom total mutation burden (TMB; mutations/megabase [Mb]) was assessed, 5 (15%) had high TMB (≥20 mutations/Mb), 18 (53%) had intermediate TMB (6–19 mutations/Mb), and 11 (32%) had low TMB (≤5 mutations/Mb). We next tested 13 patients' plasma cell‐free DNA with droplet digital polymerase chain reaction for the presence of XPO1 E571 mutation, which was confirmed in the plasma of 31% of patients. In three patients with serially collected plasma samples, XPO1 E571K allelic frequency changes corresponded with changes in tumor size on conventional radiographic imaging.Conclusion.The study demonstrates that comprehensive genomic profiling of archival Hodgkin lymphoma tumor samples is feasible and leads to the identification of genes that are recurrently mutated and that Hodgkin lymphoma has increased mutation burden in the majority of samples analyzed. Furthermore, tracking of XPO1 E571 mutant allele frequency in a subset of patients may also represent a potential disease‐monitoring strategy and warrants further investigation.Implications for Practice.This study provides the first evidence that comprehensive genomic profiling can be performed to map the genomic landscape of Hodgkin lymphoma and that a subpopulation of patients has mutations in TP53, B2M, XPO1, and other genes. It was found that 15% of patients have high mutation burden, which, in cancers such as melanoma, may indicate sensitivity to immune checkpoint inhibitors, and may thus be explored for Hodgkin lymphoma. Lastly, this work demonstrates that changes in the mutant allele frequency of XPO1 in serially collected plasma cell‐free DNA samples correspond with treatment outcomes measured with conventional radiographic imaging.

https://ift.tt/2KVC10B

Amyloid Precursor Protein Is Associated with Aggressive Behavior in Nonluminal Breast Cancers

AbstractBackground.β‐amyloid precursor protein (APP), a potential target for Alzheimer's disease treatment, has recently been shown to take part in carcinogenesis. Increased APP promotes migration, survival, and proliferation in breast cancer cell lines. We examined the clinical value of APP in breast cancers. A comprehensive examination of clinicopathological features related to APP expression in a large cohort of breast cancers and the corresponding metastatic lymph nodes was performed. APP expression and its prognostic impact in different breast cancer subtypes were examined.Results.APP was highly expressed in nonluminal breast cancers and correlated with features associated with nonluminal breast cancers (including higher grade, the presence of necrosis, and higher proliferative index, growth factor receptor, and basal marker expression). Multivariate Cox hazard analysis demonstrated that APP was an independent adverse prognostic factor of disease‐free survival (DFS; hazard ratio [HR], 2.090; p = .013; 95% confidence interval [CI], 1.165–3.748) and breast cancer‐specific survival (BCSS; HR, 2.631; p = .002; 95% CI, 1.408–4.915) in the nonluminal group. The independent prognostic impact was also seen in triple negative breast cancers. Interestingly, a higher expression of APP was found in nodal metastasis compared with primary tumor. Such APP upregulation was correlated with further distal metastasis and poorer outcome (DFS: log‐rank, 12.848; p < .001; BCSS: log‐rank, 13.947; p < .001).Conclusion.Our findings provided evidence of oncogenic roles of APP in clinical breast cancers. Patients with positive APP expression, particularly those with APP upregulation in lymph node metastases, may require vigilant monitoring of their disease and more aggressive therapy.Implications for Practice.β‐amyloid precursor protein (APP), a potential target for Alzheimer's disease, has recently been implicated in oncogenesis. Here, we provide evidence of its roles in clinical breast cancers. Positive APP expression was found to be an independent prognostic factor in nonluminal cancers, particularly triple negative breast cancers (TNBCs). Interestingly, a higher APP in nodal metastases was associated with distal metastases. TNBCs are heterogeneous and currently have no available target therapy. APP could have therapeutic potential and be used to define the more aggressive cases in TNBCs. Current prognostic analysis is based on primary tumor. Our data suggest that investigation of nodal metastases could provide additional prognostic value.

https://ift.tt/2nDs0vJ

Translation and cultural adaptation of the CLEFT-Q into Arabic, Dutch, Hindi, Swedish, and Turkish

Abstract

Background

Treatment for cleft lip and/or palate (CL/P) involves a multidisciplinary team of experts who aim to improve ones' appearance, health-related quality of life, and speech function. To appropriately measure outcomes in CL/P from the patient perspective, a CL/P-specific patient-reported outcome (PRO) instrument is needed. The CLEFT-Q is a self-report PRO instrument developed to evaluate treatment outcomes in patients with CL/P. The aim of this study was to translate and culturally adapt the CLEFT-Q.

Methods

The CLEFT-Q was translated and culturally adapted from English into Arabic, Dutch, Hindi, Swedish, and Turkish using guidelines set forth by the International Society for Pharmacoeconomics and Outcomes Research. For each language, two forward translations, one back translation, and cognitive debriefing interviews with patients were conducted.

Results

The field test version of the CLEFT-Q consisted of 154 items across 13 scales. Forward translations for each language revealed few items that were difficult to translate into the various languages. Comparison of each back translation to the English version identified that a change in the meaning of an item was more common in the Turkish (n = 40, 26%) and Arabic (n = 17, 11%) translations, and required re-translation. Cognitive debriefing interviews involved 41 participants from plastic surgery centers in India, Qatar, Sweden, the Netherlands, and Turkey. Participants reported few difficulties in understanding the items, instructions, and response options in each CLEFT-Q translation.

Conclusions

Semantic, idiomatic, experiential, and conceptual equivalence of the CLEFT-Q was achieved for all language versions, thus providing evidence of the CLEFT-Q's transferability to other languages and cultures.

Level of Evidence: Not ratable

https://ift.tt/2MhATtp

Facial reconstruction in Italy during the First World War

Abstract

Background

The field of plastic surgery, and in particular facial reconstruction, advanced rapidly during the First World War, but the Italian contribution is little known.

Methods

This paper explores wartime experience in Italy, with particular reference to the unit of Amedeo Perna in Rome, as illustrated by the diary and photographs taken by Emerin Keene, the daughter of the American Consul-General in Rome in 1918, who worked as a nurse in the Ospedale Stomatoiatrico, located in the Villa Massimo.

Results

The diary of her nursing experience provides an insight into the workings and day-to-day life of the hospital.

Conclusions

Whilst there has been interest in, and publication on developments in Great Britain, France and Germany, no significant review of the Italian experience has been undertaken. This article examines the clinical material described by Emerin Keene and the contributions of other Italian contributors to wartime facial surgery, setting these in the context of developments elsewhere in Europe, but further research on what appears to be extensive Italian work in the First World War seems merited.

Level of Evidence: not ratable

https://ift.tt/2wfs48X

Influence of sleep on developing brain functions and structures in children and adolescents: A systematic review

This systematic review examined the associations between sleep and brain functions and structures in children and adolescents aged 1 to 17 years. Included studies (n=24) were peer-reviewed and met the a priori determined population (apparently healthy children and adolescents aged 1 year to 17 years), intervention/exposure/comparator (various sleep characteristics including duration, architecture, quality, timing), and outcome criteria (brain functions and/or brain structures, excluding cognitive function outcomes).

https://ift.tt/2vHtvNY

Is the informal economic activity a determinant of environmental quality?

Abstract

This study aims to investigate whether the size of the informal economic activity is a determinant of the environmental quality in the case of Turkey. First, the MIMIC model approach will be used to estimate the size of the informal economic activity. Second, time series analysis will be conducted for the period from 1970 to 2014, in order to examine the effect of the size of the informal economic activity on the environmental quality by conducting Carrion-i-Silvestre et al. (Economet Theor 25:1754, 2009) unit root tests, Bound test and Maki (Econ Model 29:2011–2015, 2012) cointegration tests that allow structural breaks will be employed prior to the DOLS, FMOLS, and ARDL approaches for long-run and short-run models. The results suggest that informal economic activity is a positively significant determinant on the environmental quality. Moreover, this paper suggests that both formal and informal economies have significant impact on environmental quality. However, formal economy exerts positively higher effects on the environmental quality compared to informal economy. Turkish authorities need to pay more attention on both formal and informal economic activities to prevent environmental degradation in Turkey.

https://ift.tt/2MMEgoH

The Relation Between Epicardial Fat Tissue Thickness and TSH Receptor Antibody in Hyperthyroidism

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0664-7746

Background Although hyperthyroidism may be associated with atherosclerosis, its pathogenesis is not well known. TSH receptor antibody (TRAb) has been shown to be responsible for increased orbital fat tissue in Graves ophthalmopathy. Epicardial fat tissue thickness (EFT) has been found to be increased in case of overt hyperthyroidism. In our study, we aimed to investigate if TRAb is associated with the increased EFT in newly diagnosed hyperthyroidism. Methods Twenty six TRAb positive (group 1) and 26 TRAb negative (group 2) newly diagnosed patients with hyperthyroidism, and 26 healthy control subjects (group 3) were enrolled. EFT was measured by the same cardiologist using an echocardiography device. Serum TRAb levels were measured by the radio-receptor assay and levels above 1.75 IU/L were considered as positive. Results There was no difference among groups in terms of age, gender and body mass index. Although there was no significant difference between group 1 and 2, both group 1 (0.38±0.15 cm) and group 2 (0.4±0.17 cm) had significantly higher EFT levels when compared to group 3 (0.25±0.06 cm) (p=0.004 and p=0.001, respectively). However we did not find any correlation between TRAb and EFT levels. Conclusion The results of our study suggested that EFT was increased in hyperthyroidism and this increasing was not dependent of TRAb level. EFT elevation might be depending directly to the cardiovascular effects of hyperthyroidism.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

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Acute Administration of Tibolone Prevents Oxidative Stress in Ovariectomized Rats Fed High-Fat-and-Fructose Diet

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0659-9928

In addition to oxidative stress due to the increase of free radicals, estrogen deficiency is associated with changes in enzymatic activity, glutathione redox ratio (GSH/GSSG), and the content of oxidative markers such as malondialdehyde. Tibolone, a synthetic steroid, has been used as an elective treatment for the relief of menopausal symptoms. However, the acute effects of hormonal therapy with tibolone on metabolic parameters and oxidative stress markers associated with the first stages of estrogen deficiency are still unknown. The study aimed to evaluate if the acute administration of tibolone reduces oxidative stress in ovariectomized rats fed high-fat-and-fructose diet. Rats were fed a standard diet or a diet consisting of 10% lard-supplemented chow and 20% high-fructose syrup in the drinking water plus tibolone or vehicle for seven days. Weight, cholesterol, triglycerides, and glucose levels, as well as antioxidant enzymes and oxidative stress markers were quantified in the serum of each experimental group. It was observed that seven days of diet and tibolone treatment in the ovariectomized group reduced weight, triglycerides, cholesterol, glucose levels and advanced glycation end products but did not change GSH/GSSG ratio nor the enzymatic activity of superoxide dismutase. Also, both glutathione peroxidase and glutathione reductase activity decreased, as well as malondialdehyde levels. These results suggest that the acute treatment with tibolone prevented the changes in the metabolic parameters analyzed as well as the increase in the levels of malondialdehyde and AGEs induced by ovariectomy and high-fat diet.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

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The Abdominal Aortic Intima-Media Thickness Increases in Patients with Primary Hyperparathyroidism

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0664-7820

Background We aimed to determine whether there is an increase in aortic intima-media thickness values measured from the abdominal aorta in addition to the traditional carotid intima-media thickness in patients with primary hyperparathyroidism and to determine the parameters closely related to aortic intima-media thickness. Methods This perspective study included 65 primary hyperparathyroidism patients and 30 healthy-controls. Routine laboratory tests for the diagnosis of hyperparathyroidism and vascular ultrasound examinations were performed. Common carotid, internal carotid, and abdominal aortic intima media thickness were measured. The participants of the study was divided into 3 groups as the control (Group–I), the medical treatment (Group–II) due to primary hyperparathyroidism, and the planned surgery (group–III). Results Aortic intima-media thickness, serum urea, creatinine, glucose, uric acid, hs-CRP, parathyroid hormone, calcium and urine calcium levels increased significantly from Group–I to Group–III and T–scores and serum phosphorus in levels decreased significantly. Carotid intima-media thicknesses were not significantly different between the groups. Serum and urinary calcium levels were independently associated with aortic intima-media thickness. Aortic intima-media thickness, serum phosphorus, parathyroid hormone, T-scores, serum and urinary calcium levels are independent indicators for Group–III. When the cut-off value of aortic intima-media thickness was taken as 1.5 mm, 80.6% sensitivity and 89.1% specificity were determined for patients who would go to surgery. Conclusion Serum and urine calcium levels were independently associated with aortic intima-media thickness. Aortic intima-media thickness is more useful than carotid intima-media thickness in showing vascular organ involvement in patients with primary hyperparathyroidism.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

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Perioperative Management of Endocrine Active Adrenal Tumors

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0654-5251

Endocrine active adrenal tumors are associated with a relevant risk of complications during surgery, either due to direct hemodynamic effects of the hormone excess or due to hormone related comorbidities. Over the last decades, careful preoperative evaluation and improved peri-interventional medical management of affected patients has resulted in a significant reduction of perioperative complications. In addition, improvement in anesthesia and surgical techniques with the feasibility of laparoscopic adrenalectomy have contributed to reduce morbidity. Nevertheless, there are still several challenges to be considered in the perioperative care of these patients. Due to the rarity of functionally active adrenal tumors, there are no prospective data available to guide clinical management. Accordingly, most recommendations are based on retrospective data analysis, expert opinion or carry weak evidence based on small series or case reports. The aim of this review is to summarize the current knowledge and to suggest practical approaches to reduce perioperative complications in endocrine active adrenal tumors. This review exclusively deals with data from adult patients with functionally active adrenal tumors.
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© Georg Thieme Verlag KG Stuttgart · New York

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Editorial Board and Contents

Publication date: September 2018

Source: Trends in Endocrinology & Metabolism, Volume 29, Issue 9

Author(s):

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Transurethral thulium laser enucleation versus resection of the prostate for treating benign prostatic hyperplasia: a retrospective study

Abstract

This study aimed to compare the clinical outcomes between transurethral thulium laser enucleation of the prostate (ThuLEP) and transurethral thulium laser resection of the prostate (ThuLRP) for treating benign prostatic hyperplasia (BPH). From May 2014 to August 2015, 212 patients underwent ThuLRP and 188 patients underwent ThuLEP. The ThuLEP group was further divided into two subgroups according to the ways the prostate was taken out. The perioperative parameters were recorded and analyzed. The international prostate symptom score (IPSS), quality-of-life (QoL) score, maximum flow rate (Qmax), and postvoid residual urine volume (PVR) in both groups were estimated and compared 3, 6, and 12 months after surgery. No significant difference was observed between the groups in terms of irrigated time, irrigated volume, catheterization time, and hospital stay. However, the significantly lower hemoglobin drop was observed in the ThuLRP group compared with the ThuLEP group. The ThuLEP group with a morcellator required a shorter operation time for patients with large prostate volume (> 60 mL) compared with the ThuLRP and ThuLEP groups without a morcellator. During 12 months of follow-up, IPSS, Qmax, QoL, and PVR improved significantly without significant differences between the groups. No severe complications were reported; however, the occurrence of transient urge incontinence was higher after ThuLEP compared with ThuLRP, and the proportion of urinary tract infection after surgery was higher in ThuLRP than in ThuLEP. ThuLRP and ThuLEP are safe and efficient for treating patients with symptomatic BPH. ThuLRP offers advantages in terms of minimal blood loss.

https://ift.tt/2Oz7mIs

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Abstract

Extracorporeal shock wave therapy (ESWT) has been extensively studied for its multiple biological properties, and although it is widely applied in esthetical procedures, little is known about its effects on the epidermis and dermis. In this study, a histological and immunohistochemical study of the effects of ESWT was performed on rat skin. Forty-five female rats were treated with one or two sessions of ESWT and sacrificed on days 1, 7, 14, and 21 after treatment. The samples were histologically processed and then morphometric analyses were performed to assess the epidermis, dermis, and subcutaneous fat tissue thickness. Immunohistochemical reactions were also performed against the antibodies: basic fibroblastic growth factor (FGF2), its receptor (FGFR1), and α-smooth muscle actin. Slides were scanned and digitally assessed, to determine the microvessel density (MVD) and digital scoring of the immunohistochemical staining. The results showed that ESWT produced a significantly higher collagen content, MVD, and epidermis and dermis thickness than the control, non-treated group. Both in epidermis and dermis, FGF2 was overexpressed in the ESWT-treated groups, whereas FGFR1 was increased only in the group treated with two ESWT sessions at 21-days post-treatment. The ESWT-treated groups have also shown diminished thickness of subcutaneous fat tissue. In conclusion, ESWT induces neocollagenesis and neoangiogenesis, and upregulates the FGF2 expression, particularly in the groups treated with two sessions. Furthermore, it was demonstrated that overexpression of FGF2 on skins treated with ESWT seems to be a key role on its mechanism of action.

https://ift.tt/2nG4q1s

Clinical Thyroidology®for the Public – Highlighted Article

From Clinical Thyroidology^® for the Public: Thyroid hormone is necessary for development and growth of brain in developing babies during pregnancy. Studies have shown that hypothyroidism and low thyroid hormone levels without hypothyroidism may be associated with some developmental problems in children. Read More…

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Evaluation of the disintegration of linen fabric under composting conditions

Abstract

In recent years, about 10% of the total wastes generated around the world were fabric wastes and, due to the large volume of these wastes, should be well managed. Among the various types of fabrics, some have greater biodegradability and can be decomposed at the acceptable rates under controlled conditions. In this study, the disintegration of linen fabric was investigated under composting conditions. During the composting process, temperature, moisture, and aeration were controlled. According to FTIR spectra of linen fabrics during the composting process, the disintegration of linen fibers was identified as the breakdown of carbonyl groups and hydrogen bonds of cellulosic chains. Regarding the SEM images of linen fabrics, the composting process in the first 45 days led to the breakdown of the fibers, and in the second 45 days of the process, most of the fibers were degraded. Since in the second 45 days of the process, the compost pile temperature is always between 39 and 44 °C and 65–70 °C, it can be concluded that the rate of microbial disintegration of the linen fabric is higher at these temperatures. At the end of the test, the disintegration value of the linen fabric was 55% and the weight loss due to organic matter conversion was 61%. The samples weight loss showed that linen fabric has high biodegradability under composting conditions. The germination index (GI) of the resulting compost was 73.88%, which indicates the produced compost is mature.

https://ift.tt/2w2ISQe

Microplastics in Talitrus saltator (Crustacea, Amphipoda): new evidence of ingestion from natural contexts

Abstract

Using Fourier transform infrared spectroscopy (FT-IR) measurements and comparing the spectrum peaks (range 4000–600 cm⁻¹) with reference spectra database and instrument libraries, we observed new evidence of the ingestion of microplastic particles analyzing the digestive tracts of Talitrus saltator. Specimens, sampled in central Italy, probably ingested the particles with natural detritus. Since worldwide many species of invertebrates and vertebrates (e.g., birds) feed on Amphipoda along coastal ecosystems, we hypothesized that microplastic in these crustaceans can be accumulated along the food chain.

https://ift.tt/2MiLww7

Eliminating redundant spatial variation to better understand the variance of interest of soil potentially toxic elements at different sampling scales in different soil types south of Nanjing, China

Abstract

Sampling scale and prediction of spatial distribution are essential in surveys of soil metal pollution. Sufficient sampling density encompassing the principal spatial sources of variance and prediction of polluted areas with the help of soil maps makes pollution evaluation more reliable and subsequent soil remediation assessment more efficient. Two soil sampling schemes, using 232 points at 2-km intervals in 2002 for sampling at county scale and 109 points at 200–1000-m intervals in 2012 at town scale, were used to study the potentially toxic metals Cu, Cd, Cr, Hg, Ni, Pb, Zn, and the metalloid As in an urban-rural hinge area. We focused on finding characteristics of the explanatory power of soil type toward different sampling scales from 200 to 2000 m, a routine sampling scale in practice for remediation of soil potentially toxic elements (PTEs). We also attempted to eliminate the redundant spatial variation to better understand the variance of soil PTEs. Spatial variation of PTEs at different scales was compared and estimated using soil map units based on geostatistical methods. The explanatory power of the soil map units selected at different scales was significantly different at P < 0.01 and the smaller scales better explained the spatial variance. Anthropic activities profoundly affected the contents of PTEs in soils and the amounts of anthropogenic pollutants released often exceed the contribution from natural sources. Variances of interest of Cr and Cu were underestimated by 72.4 and 32.8%, respectively, due to soil type as a factor but were overestimated for other elements by percentages following the sequence Zn (45.4%) > Hg (28.6%) > Pb (28.8%) > Ni (26.73%) > As (13.7%) > Cd (10.5%). Eliminating variances of zero interest would be helpful in increasing the effectiveness of remediation of metal-contaminated soils.

https://ift.tt/2w6sfDe

Effects of microplastics on trophic parameters, abundance and metabolic activities of seawater and fish gut bacteria in mesocosm conditions

Abstract

Plastic pollution is an emerging threat with severe implications on animals' and environmental health. Nevertheless, interactions of plastic particles with both microbial structure and metabolism are a new research challenge that needs to be elucidated yet. To improve knowledge on the effects played by microplastics on free-living and fish gut-associated microbial community in aquatic environments, a 90-day study was performed in three replicated mesocosms (control-CTRL, native polyvinyl chloride-MPV and weathered polyvinyl chloride-MPI), where sea bass specimens were hosted. In CTRL mesocosm, fish was fed with no-plastic-added food, whilst in MPV and MPI food was supplemented with native or exposed to polluted waters polyvinylchloride pellets, respectively. Particulate organic carbon (POC) and nitrogen, total and culturable bacteria, extracellular enzymatic activities, and microbial community substrate utilization profiles were analyzed. POC values were lower in MPI than MPV and CRTL mesocosms. Microplastics did not affect severely bacterial metabolism, although enzymatic activities decreased and microbes utilized a lower number of carbon substrates in MPI than MPV and CTRL. No shifts in the bacterial community composition of fish gut microflora were observed by denaturing gradient gel electrophoresis fingerprinting analysis.

https://ift.tt/2nCHos7

Cd and Pb accumulation characteristics of phytostabilizer Athyrium wardii (Hook.) grown in soils contaminated with Cd and Pb

Abstract

Interactions between heavy metals in soil could affect soil heavy metal availability and plant uptake. Thus, in this study, Cd and Pb accumulation as well as plant growth of the mining ecotype (ME) and non-mining ecotype (NME) of Athyrium wardii (Hook.) in response to the exposure of Cd and Pb was investigated by a pot experiment. Although the exposure of Cd in combination with Pb further inhibited the growth of the two ecotypes in comparison with the exposure of single Cd or Pb, the ME presented lower biomass decline for the whole plant (22.0%–70.0%) than the NME among most treatments. The presence of Pb promoted Cd accumulation both in above-ground and under-ground parts of the ME. Cd concentrations in under-ground parts of the ME decreased when exposed to higher concentrations of Pb (> 600 mg kg⁻¹). Meanwhile, the presence of Cd inhibited Pb accumulation in above-ground parts of the ME and promoted Pb accumulation in under-ground parts of the ME. Pb concentrations in under-ground parts of the ME decreased when soil Cd concentrations were more than 25 mg kg⁻¹. The partial correlation analysis further demonstrated that the interactions between Cd and Pb stimulated Cd accumulation both in above-ground and under-ground parts of the ME and Pb accumulation in under-ground parts of the ME, while inhibited Pb accumulation in above-ground parts of the ME, showing great benefit for Pb phytostabilization by the ME. Among treatments, the bioaccumulation coefficients for Cd and Pb of the ME, varying from 2.71–31.05 and 20.09–78.06, were much higher than those of the NME. The translocation factors for Cd and Pb of the ME, varying from 0.26–0.52 and 0.01–0.10, were lower than those of the NME. These results indicate that the ME presented greater potential for the phytostabilization of soil contamination with Cd and Pb, especially for Pb.

https://ift.tt/2OBjlFl

Facile and environmental benign in situ synthesis of silver nanoparticles for multifunctionalization of wool fibers

Abstract

In this manuscript, we report the simple method to multifunctional wool fiber surfaces. The multifunctional wool fibers were devised with brilliant coloration, antimicrobial activity, and UV-protection property. These multifunctional properties were progressed by in situ assemble of silver nanoparticles (Ag NPs) into the wool fiber surface using green cleaner one-pot route. The proteins existing in the wool fibers acted being a redox active bio-template, facilitating the reduction of Ag⁺ to Ag⁰, with simultaneous binding of the produced Ag NPs both on the surface and within the center of the wool fibers. The entire results showed that the Ag NP in situ-incorporated wool fibers can be used as colorant wool fibers effectively, and these colored fibers also exhibit an improvement for multi-functionality properties.

https://ift.tt/2MjeDiO

Vermicompost addition influences symbiotic fungi communities associated with leek cultivated in metal-rich soils

Abstract

In the context of urban agriculture, where soils are frequently contaminated with metal(loid)s (TM), we studied the influence of vermicompost amendments on symbiotic fungal communities associated with plants grown in two metal-rich soils. Leek (Allium porrum L.) plants were grown with or without vermicompost in two metal-rich soils characterized by either geogenic or anthropogenic TM sources, to assess the influence of pollutant origin on soil-plant transfer. Fungal communities associated with the leek roots were identified by high throughput Illumina MiSeq and TM contents were measured using mass spectrometry. Vermicompost addition led to a dramatic change in the fungal community with a loss of diversity in the two tested soils. This effect could partially explain the changes in metal transfer at the soil-AMF-plant interface. Our results suggest being careful while using composts when growing edibles in contaminated soils. More generally, this study highlights the need for further research in the field of fungal communities to refine practical recommendations to gardeners.

Graphical abstract

https://ift.tt/2B9N6v7

Scholar : These new articles for South African Theatre Journal are available online

The online platform for Taylor & Francis Online content New for South African Theatre Journal and online now on Taylor & Francis Online: Book Reviews In step with the times – Mapiko masquerades of Mozambique Marie Kruger Pages: 1-4 | DOI: 10.1080/10137548.2018.1505103 Routledge Performance Archive - https://ift.tt/1txaJgs "Take a Tour" to find out more and recommend the Archive to your librarian to arrange a free trial for your institution. To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Mapping, in vivo, the uniformity of two skin properties alongside the human face by a 3D virtual approach

International Journal of Cosmetic Science, Volume 0, Issue ja, -Not available-.


https://ift.tt/2MjqMoh

Increased sensitivity of Treg cells from patients with PBC to low dose IL-12 drives their differentiation into IFN-γ secreting cells

Publication date: Available online 14 August 2018

Source: Journal of Autoimmunity

Author(s): Evaggelia Liaskou, Samita R. Patel, Gwilym Webb, Danai Bagkou Dimakou, Sarah Akiror, Mahesh Krishna, George Mells, Dave E. Jones, Simon J. Bowman, Francesca Barone, Benjamin A. Fisher, Gideon M. Hirschfield

Abstract

IL-12 is a pro-inflammatory cytokine that induces the production of interferon-γ (IFNγ) and favours the differentiation of T helper 1 (Th1) cells. In the presence of IL-12 human Treg cells acquire a Th1-like phenotype with reduced suppressive activity in vitro. Primary biliary cholangitis (PBC) is an autoimmune cholestatic liver disease characterised by high Th1 and Th17 infiltrating cells, reduced frequencies of Treg cells, and a genetic association with IL-12 signalling. Herein, we sought to evaluate the IL-12 signalling pathway in PBC pathology, by studying human samples from patients with PBC, alongside those with primary Sjögren's syndrome (pSS)(autoimmune disease with IL-12 signalling gene association), primary sclerosing cholangitis (PSC) (cholestatic liver disease without IL-12 gene association) and healthy individuals. Our data revealed that TLR stimulation of PBC (n = 17) and pSS monocytes (n = 6) resulted in significant induction of IL12A mRNA (p < 0.05, p < 0.01, respectively) compared to PSC monocytes (n = 13) and at similar levels to HC monocytes (n = 8). PSC monocytes expressed significantly less IL-12p70 (108 pg/ml, mean) and IL-23 (358 pg/ml) compared to HC (458 pg/ml and 951 pg/ml, respectively) (p < 0.01, p < 0.05). Treg cells from patients with PBC (n = 16) and pSS (n = 3) but not PSC (n = 10) and HC (n = 8) responded to low dose (10 ng/ml) IL-12 stimulation by significant upregulation of IFNγ (mean 277 and 254 pg/ml, respectively) compared to PSC and HC Treg cells (mean 22 and 77 pg/ml, respectively)(p < 0.05). This effect was mediated by the rapid and strong phosphorylation of STAT4 on Treg cells from patients with PBC and pSS (p < 0.05) but not PSC and HC. In the liver of patients with PBC (n = 7) a significantly higher proportion of IL-12Rβ2⁺Tregs (16% on average) was detected (p < 0.05) compared to other liver disease controls (5%)(n = 18) which also showed ex vivo high IFNG and TBET expression. CONCLUSION: Our data show an increased sensitivity of PBC and pSS Treg cells to low dose IL-12 stimulation, providing ongoing support for the importance of the IL12-IL-12Rβ2-STAT4 pathway on Treg cells in disease pathogenesis and potentially treatment.

https://ift.tt/2P4bO2W

Unilateral cochlea sparing in locoregionally advanced head and neck cancer: a planning study

Abstract

Background

Cochlea sparing can reduce late ototoxicity in head and neck cancer patients treated with cisplatin-based radiochemotherapy. In this situation, a mean cochlear dose (MCD) constraint of 10 Gy has been suggested by others based on the dose–effect relationship of clinical data. We aimed to investigate whether this is feasible for primary and postoperative radiochemotherapy in locoregionally advanced tumors without compromising target coverage.

Patients and methods

Ten patients treated with definitive and ten patients treated with adjuvant intensity-modulated radiotherapy (IMRT) and concurrent chemotherapy were investigated. The cochleae and a planning risk volume (PRV) with a 3 mm margin were newly delineated, whereas target volumes and other organs at risk were not changed. The initial plan was recalculated with a constraint of 10 Gy (MCD) on the low-risk side. The quality of the resulting plan was evaluated using the difference in the equivalent uniform dose (EUD).

Results

A unilateral MCD of below 10 Gy could be achieved in every patient. The mean MCD was 6.8 Gy in the adjuvant cohort and 7.6 Gy in the definitive cohort, while the non-spared side showed a mean MCD of 18.7 and 30.3 Gy, respectively. The mean PRV doses were 7.8 and 8.4 Gy for the spared side and 18.5 and 29.8 Gy for the non-spared side, respectively. The mean EUD values of the initial and recalculated plans were identical. Target volume was not compromised.

Conclusion

Unilateral cochlea sparing with an MCD of less than 10 Gy is feasible without compromising the target volume or dose coverage in locoregionally advanced head and neck cancer patients treated with IMRT. A prospective evaluation of the clinical benefit of this approach as well as further investigation of the dose–response relationship for future treatment modification appears promising.

https://ift.tt/2BcSvBT

Diagnosis and ecotoxicological risk assessment of 49 elements in sludge from wastewater treatment plants of Chongqing and Xiamen cities, China

Abstract

Limited information about the sludge quality is a major constraint for its usage and proper disposal. This study investigated the occurrence of 49 elements in sludge from 11 wastewater treatment plants (WWTPs) in Chongqing and Xiamen cities of China. The concentration of 46-detected elements ranged from 16.2 μg kg⁻¹ (Pt) to 55.0 g kg⁻¹ (Al) on dry solid basis in the sludge. The enrichment factor of most of the elements was > 1.5, indicating their possible anthropogenic origin. The precious metals had considerably higher enrichment factor ranging from 56.3 to 200,000. Principal component analysis clustered the samples from Chongqing and Xiamen separately to suggest strong spatial variations. Contamination factor, pollution loading index, and integrated pollution degree were calculated to evaluate the elemental pollution risk. The pollution loading index indicated unpolluted to highly polluted levels of the elements in the sludge. In addition, results from the ecotoxicological risk index showed an individual low to very high ecotoxicological risk posed by eight metal(loid)s (As, Cd, Cr, Cu, Mn, Ni, Pb, and Zn) in the WWTPs.

https://ift.tt/2nJIFOl

Environmental photochemical fate and UVC degradation of sodium levothyroxine in aqueous medium

Abstract

The synthetic hormone sodium levothyroxine (LTX) is one of the most prescribed drugs in the world and the most effective in hypothyroidism treatment. The presence of LTX in the environment has become a matter of major concern due to the widespread use of this hormone and by the fact that it is only partially removed in conventional water and sewage treatment plants. However, information regarding the photochemical fate of this hormone in environmental or engineered systems is scarce in the literature. In this work, the sunlight-driven direct and indirect LTX degradation was investigated by determining the photolysis quantum yield, Φ_LTX = 3.80 (± 0.02) × 10⁻⁵, as well as the second-order kinetic constants of the reactions with hydroxyl radicals, k_LTX,•OH = 1.50 (± 0.01) × 10¹⁰ L mol⁻¹ s⁻¹ and singlet oxygen, k_LTX,1O2 = 1.47 (± 0.66) × 10⁸ L mol⁻¹ s⁻¹. Mathematical simulations indicate that LTX photodegradation is favored in shallow, nitrite-rich, and dissolved organic matter (DOM)-poor environments, with LTX half-life times varying from less than 10 days to about 80 days. LTX removals of 85 and 95% were achieved by UVC photolysis and UVC/H₂O₂ after 120 min, respectively. Three transformation products, triiodothyronine, diiodothyronine, and diiodotyrosine, were identified during LTX degradation by the UVC-based processes studied. The results herein regarding photo-induced kinetics coupled with environmental fate simulations may help evaluate LTX persistence and also the design of water and wastewater treatment processes.

https://ift.tt/2MH5KMe

Removal mechanism of sulfamethazine and its intermediates from water by a rotating advanced oxidation contactor equipped with TiO 2 –high-silica zeolite composite sheets

Abstract

The removal of antibiotic sulfamethazine (SMT) and its intermediates from water was investigated using a rotating advanced oxidation contactor (RAOC) equipped with TiO₂-high-silica zeolite composite sheets. SMT was readily removed from water through adsorption onto high-silica zeolite and photocatalytic decomposition by TiO₂ inside the composite sheet. Some degradation intermediates were retained and photocatalytically decomposed inside the composite sheet. Relatively hydrophobic intermediates such as hydroxylated SMT were captured inside the sheets, whereas hydrophilic intermediates were distributed in water. This was attributed to the hydrophobic interactions in the adsorption mechanism of high-silica zeolite. The time courses of the NH₄⁺, NO₃⁻, and SO₄²⁻ ion concentration during the RAOC treatment of SMT were evaluated. After treatment by RAOC for 24 h, approximately 94% of nitrogen derived from the amino and sulfanilamide groups and 39% of sulfur from the sulfanilamide group were mineralized, which indicated that the mineralization behavior of SMT treated by RAOC was different from that treated by TiO₂ powder. These results strongly suggested that the dissociation of the amino group and cleavage of the sulfonamide group and subsequent dissociation of the amino group preferentially proceeded inside the composite sheets.

https://ift.tt/2MoAq8i

Scholar : Decannulation - νέα αποτελέσματα

Anterior–posterior cricoid split combined with silastic T-tube stenting for subglottic stenosis in children: a single surgeon's experience

Y Bitoh, Y Okata, J Tsugawa, H Miyauchi, Y Aida… - Pediatric Surgery …, 2018

… The surgical management of subglottic stenosis (SGS) is still challenging
for pediatric surgeons and otolaryngolo- gists. The goals of management
are decannulation and normal physiologic breathing … because of the …

Rigid dilatation of pediatric laryngotracheal stenosis as an adequate alternative to balloon dilatation

D Yafit, O Cavel, OJ Ungar, O Wasserzug… - European Archives of Oto …, 2018

… Cary, NC, USA). Results Forty-eight of the 68 cases (70.6%) had a successful out-
come, of which 27 (39.7%) underwent decannulation and 21 (30.9%) tracheostomy-
independent patients had clinical improvement. The other 20 …

Sequelae of Cardiopulmonary Bypass-Induced Pulmonary Injury

ML Summar, FW Barr - US Patent App. 15/853,248, 2018

… The citrulline bolus may be administered about 30 minutes after cardio pulmonary bypass
decannulation … In many embodiments, a bolus of about 20 mg/kg of citrulline may be
administered after decannulation from cardiopulmonary bypass …

[PDF] Extracorporeal Membrane Oxygention (ECMO) Pada Pasien

M Mujahidin - (JAI) Jurnal Anestesiologi Indonesia, 2018

… mengurangi risiko pembekuan d. Echocardiography di gunakan untuk
menilai fungsi jantung selama weaning dari ECMO e. Setelah fungsi
jantung membaik setelah lakukan dekanulasi ECMO , arus ECMO harus …

 

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Scholar : Laryngomalacia - νέα αποτελέσματα

Twinkle-associated mitochondrial DNA depletion

S Remtulla, CT Nguyen, C Prasad, C Campbell - Pediatric Neurology, 2018

… By age 4 months, she developed stridor requiring supraglottoplasty for laryngomalacia;
hypertension, treated with amlodipine; bilateral asymmetric ptosis, not responsive to
pyridostigmine trial; and refractory status epilepticus requiring pentobarbital infusion …

Anterior–posterior cricoid split combined with silastic T-tube stenting for subglottic stenosis in children: a single surgeon's experience

Y Bitoh, Y Okata, J Tsugawa, H Miyauchi, Y Aida… - Pediatric Surgery …, 2018

… Germany). Among these children, we selected those with grade II and III as candidates
of our procedure and excluded those with other airway anomalies, including
tracheomala- cia, congenital tracheal stenosis, and laryngomalacia …

[PDF] New frontiers and emerging applications of 3D printing in ENT surgery: a systematic review of the literature

P Canzi, M Magnetto, S Marconi, P Morbini… - Acta Otorhinolaryngologica …, 2018

… More recently, Kavanagh et al. developed a 3DP paediat- ric laryngeal model
reproducing several challenging sur- gical conditions (eg subglottic cysts,
laryngomalacia, subglottic stenosis and laryngeal clefts) 62. Customised …

[PDF] MUCOPOLYSACCHARIDOSIS AND ANAESTHESIA: THE IMPACT OF ENZYME REPLACEMENT THERAPY ON MODERN AIRWAY MANAGEMENT IN ASIAN …

MC Lin, CC Chen - INDIAN JOURNAL OF APPLIED RESEARCH, 2018

… MPS type I II III IV VI Patient numbers 2 15 4 4 3 Gender (Male/Female) 0 /
2 15 / 0 3 / 1 3 / 1 2 / 1 ERT / No ERT treatment 2 / 0 5 / 10 0 / 4 3 / 1 3 / 0
Anaesthetics 9 31 8 15 9 Pre-op bronchoscope Adenoid hypertrophy 3 17 …

[HTML] GI, Pediatrics, Toxicology

J Werner

… Mild patchy sloughing and nodularity distally; One small erosion in the stomach;
Normal duodenum; Congenital laryngomalacia and elliptical cricoid consistent with
congenital subglottic stenosis. Figure 1a. Figure 1b. Figure 1c …

[HTML] Related Products

J Furmick, L Malburg, A Leetch, C Nozicka

… infectious causes of stridor. Foreign body, anaphylaxis, laryngomalacia,
laryngotracheitis/croup, bacterial tracheitis, and epiglottitis all are common causes
of stridor and will be discussed in more detail later. Wheezing in respiratory …

 

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Scholar : ΛΟΓΟΣ - νέα αποτελέσματα

[PDF] A Psicologia de Epicteto

D Luz - 2018

… A natureza para os estoicos é o mesmo que a divindade, que é o mesmo
que o λόγος (razão). Sendo assim, a religiosidade tão presente nos discursos
de Epicteto pode … 105 capaz de usar aquilo que existe de divino na natureza …

[PDF] Συστήματα Ψηφιακών Ανώνυμων Ερωτηματολoγίων και Κρυπτογραφικές Κυκλικές Υπογραφές

ΔΣ Κολονέλος - 2018

… Σε γενικές γραμμές, αυτός είναι ο λόγος που χτίζουμε κρυπτογραφικά ασφαλή
συστήματα χωρίς να υποθέτουμε έμπιστες τρίτες αρχές … Ο λόγος είναι ότι οι εκλογές
είναι κάτι που θεωρείται σημαντικό από αυτούς που ψηφίζουν …

Oberflächenbeschichtungen von Silizium, HOPG und Graphitanoden mittels Thiol-En/In Click-Chemie, deren Charakterisierung mit XPS und ToF-SIMS sowie …

D Moock - 2018

Page 1. Oberfl¨achenbeschichtungen von Silizium, HOPG und Graphitanoden mittels
Thiol-En/In Click-Chemie, deren Charakterisierung mit XPS und ToF-SIMS sowie
elektrochemische Untersuchung Dominique Moock λογος Page 2. Page 3 …

Новые технологии в методике преподавания военных дисциплин

ИИ Мехович - 2018

… науки. Технология (от др. греч τέχνη — искусство, мастерство, умение; λόγος —
мысль, причина; методика, способ производства) — в широком смысле —
совокупность методов, процессов и материалов, Page 3. 140 …

Ο ρόλος του ανοσοποιητικού συστήματος στη διατροφικής αιτιολογία λιπώδη διήθηση του ήπατος

Μ Μωυσίδου - 2018

… WT). Έγχυση λειτουργικών λεμφοκυττάρων σε Rag1-/- μύες αποκάλυψε ότι η έλλειψη
των T, και συγκεκριμένα των CD8+ T λεμφοκυττάρων, ήταν ο κύριος λόγος της
αυξημένης μεταβολικής τους δραστηριότητας. Συγκεκριμένα …

Budo als Erziehungs-und Bildungskonzept am Beispiel der japanischen Kampfkunst Aikido

M Gleiß

Page 1. Martin Gleiß Budo als Erziehungs- und Bildungskonzept am Beispiel
der japanischen Kampfkunst Aikido λογος Page 2. Page 3. Martin Gleiß Budo
als Erziehungs- und Bildungskonzept am Beispiel der japanischen Kampfkunst …

Prozesse beim gemeinsamen Lernen aus der Sicht von Schülerinnen und Schülern: Eine Studie im jahrgangsübergreifenden Unterricht einer Grundschule

N Brück

Page 1. Herausgegeben von Thomas Trautmann Nina Brück Prozesse beim gemeinsamen
Lernen aus der Sicht von Schülerinnen und Schülern Eine Studie im
jahrgangsübergreifenden Unterricht einer Grundschule λογος Page 2. Page 3 …

HEIDEGGERA FENOMENOLOGICZNA METODA INTERPRETACJI KANTOWSKIEJ ESTETYKI TRANSCENDENTALNEJ

F Borek

… już jakieś „jawienie się". Drugi człon wyrazu „fenomenologia" to λόγος, który oznacza
δηλούν, czyli „ujawniać coś o czym w mowie «mowa»". Λόγος umożli- wia
zobaczenie tego, o czym jest mowa. Fenomenologia to więc w …

CĂRŢI PRIMITE LA REDACŢIE

MD Vadana, C Stroe

… nimicului; § 10. Conceptul meontologic de λόγος; § 11. „Focul cosmic" – probleme
metodologice; § 12. Focul cosmic şi λόγος-ul; § 13. Excurs: Destinul omului şi destinul
lumii; § 14. „Toate sunt una"; § 15. Conceptul meontologic …

[PDF] SURPASSING OF MELISSUS'HYLETIC MONISM AND PROBLEM OF NECESSITY AND CHANCE IN DEMOCRITUS'ATOMISM

GM Jakovljević - TEME, 2018

… тако и на плану означеног „испада", по диктату 6 „οὐδὲν τρῆμα μάηην γίνεηαι,
ἀλλὰ πάνηα ἐκ λόγοσ ηε καὶ ὑπ‟ ἀνάγκης." (Diels und Kranz, 1985b: 81 (D/K
67 B 2)) Page 12. 720 самог израза, да влада случај, да све …

 

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