Scholar : ΦΩΝΗ - νέα αποτελέσματα

[PDF] Ολυμπιακά αθλήματα τον 4ο αιώνα μ. Χ.

Α Χατζηφώτης - 2018

Page 1. ΠΑΝΕΠΙΣΤΗΜΙΟ ΔΥΤΙΚΗΣ ΜΑΚΕΔΟΝΙΑΣ ΠΑΙΔΑΓΩΓΙΚΗ ΣΧΟΛΗ
ΦΛΩΡΙΝΑΣ ΠΑΙΔΑΓΩΓΙΚΟ ΤΜΗΜΑ ΔΗΜΟΤΙΚΗΣ ΕΚΠΑΙΔΕΥΣΗΣ ΠΤΥΧΙΑΚΗ
ΕΡΓΑΣΙΑ του φοιτητή ΧΑΤΖΗΦΩΤΗ ΑΝΤΩΝΙΟΥ, ΑΕΜ: 3927 ΘΕΜΑ …

[PDF] Στάση και αντιλήψεις των δημοτικών υπαλλήλων για το σύστημα αξιολόγησης της απόδοσης τους: η περίπτωση του δήμου Μεταμόρφωσης

Ε Παπαθωμοπούλου - 2018

Page 1. ΠΑΝΕΠΙΣΤΗΜΙΟ ΔΥΤΙΚΗΣ ΑΤΤΙΚΗΣ ΣΧΟΛΗ ΔΙΟΙΚΗΤΙΚΩΝ, ΟΙΚΟΝΟΜΙΚΩΝ
& ΚΟΙΝΩΝΙΚΩΝ ΕΠΙΣΤΗΜΩΝ ΤΜΗΜΑ ΔΙΟΙΚΗΣΗΣ ΕΠΙΧΕΙΡΗΣΕΩΝ ΠΜΣ ΔΙΕΘΝΗΣ
ΔΙΟΙΚΗΤΙΚΗ ΤΩΝ ΕΠΙΧΕΙΡΗΣΕΩΝ ΚΑΤΕΥΘΥΝΣΗ: ΔΙΕΘΝΗΣ …

[PDF] Η συμβολή του Βιζυηνού στην επίλυση του γλωσσικού ζητήματος

Θ Παπακαρμέζη - 2018

Page 1. 1 ΠΣΤΥΗΑΚΖ ΔΡΓΑ΢ΗΑ ΠΑΝΔΠΗ΢ΣΖΜΗΟ ΓΤΣΗΚΖ΢ ΜΑΚΔΓΟΝΗΑ΢
ΠΑΗΓΑΓΧΓΗΚΟ ΣΜΖΜΑ ΓΖΜΟΣΗΚΖ΢ ΔΚΠΑΗΓΔΤ΢Ζ΢ ΘΔΜΑ: «Ζ ΢ΤΜΒΟΛΖ
ΣΟΤ ΒΗΕΤΖΝΟΤ ΢ΣΖΝ ΔΠΗΛΤ΢Ζ ΣΟΤ ΓΛΧ΢΢ΗΚΟΤ ΕΖΣΖΜΑΣΟ΢» …

Εργασία με Θύματα Εγκλημάτων Μίσους κατά ΛΟΑΤ Ανθρώπων. Ένα Πρακτικό Εγχειρίδιο.

T Theofilopoulos

… ΒΙΟΛΟΓΙΚΟ /ΑΝΑΤΟΜΙΚΟ ΦΥΛΟ ΣΕΞΟΥΑΛΙΚΗ ΕΛΞΗ Έκφ ΦΩΝΗ ΦΟΡ ΧΕΙΡΟ Τρό ένδυσ
Ταυτ … Ρομαντική έλξη Έκφραση φύλου ΦΩΝΗ, ΜΑΚΡΥΑ ΜΑΛΛΙΑ, ΦΟΡΕΜΑ, ΠΑΝΤΕΛΟΝΙΑ,
ΧΕΙΡΟΝΟΜΙΕΣ, ΜΑΚΙΓΙΑΖ Τρόπος συμπεριφοράς, ένδυσης, ομιλίας, κίνησης …

 

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Scholar : ΑΚΟΗ - νέα αποτελέσματα

[PDF] Εφαρμογές διεπαφών εγκέφαλου υπολογιστή.

Θ Μπιλερό - 2018

… οπτικό προσανατολισμό στον χώρο και την ικανότητα υπολογισμού. 3. Τον
κροταφικό λοβό, που ελέγχει την μνήμη, της ειδικές αισθήσεις όπως την ακοή
και την ικανότητα κατανόησης της προφορικής ή γραπτής γλώσσας. 4. Τον …

[PDF] Πολυπαιχνιδίσματα: οι μαθητές πρόσφυγες παίζουν και μαθαίνουν την ελληνική γλώσσα και εντάσσονται στο νέο πολιτισμό

Γ Πατεράκη - 2018

Page 1. ΠΑΝΕΠΙ΢ΣΗΜΙΟ ΔΤΣΙΚΗ΢ ΜΑΚΕΔΟΝΙΑ΢ ΠΑΙΔΑΓΩΓΙΚΗ ΢ΦΟΛΗ ΥΛΩΡΙΝΑ΢
ΠΑΙΔΑΓΩΓΙΚΟ ΣΜΗΜΑ ΔΗΜΟΣΙΚΗ΢ ΕΚΠΑΙΔΕΤ΢Η΢ Πολυπαιχνιδίςματα: Οι μαθητέσ
πρόςφυγεσ παίζουν και μαθαίνουν την ελληνική γλώςςα και εντάςςονται ςτο νέο πολιτιςμό …

[PDF] Ο ρόλος της άσκησης και της διατροφής ως μέσο πρόληψης για τις χρόνιες παθήσεις.

Ι Σύρος, Π Καλιακούδας - 2018

Page 1. 1 ΑΝΩΤΑΤΟ ΤΕΧΝΟΛΟΓΙΚΟ ΙΔΡΥΜΑ Τ.Ε.Ι. ΗΠΕΙΡΟΥ ΣΧΟΛΗ
ΕΠΑΓΓΕΛΜΑΤΩΝ ΥΓΕΙΑΣ & ΠΡΟΝΟΙΑΣ "ΤΜΗΜΑ ΝΟΣΗΛΕΥΤΙΚΗΣ"
ΔΙΠΛΩΜΑΤΙΚΗ ΕΡΓΑΣΙΑ ΕΡΓΑΣΙΑ ΜΕ ΘΕΜΑ: Ο ρόλος της άσκησης και …

 

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Scholar : Decannulation - νέα αποτελέσματα

PB3. Pharyngeal Electrical Stimulation in neurointensive care patients suffering from severe post-stroke dysphagia–Post stimulation increase of salivary substance P …

P Muhle, S Suntrup-Krueger, S Bittner, T Ruck, I Claus… - Clinical Neurophysiology, 2018

… Here, we investigated the association of PES treatment in neurointensive care patients
suffering from severe post-stroke dysphagia and salivary SP level, as well as a possible
link between SP level and decannulation success after PES. Material and methods …

[PDF] Use of Venovenous Extracorporeal Membranous Oxygenation Following Iatrogenic Tracheal Rupture

MD Kabadi - The Medicine Forum, 2018

… VV-ECMO was weaned and the patient underwent ECMO catheter
decannulation on hospital day five. She underwent tracheostomy on hospital
day fifteen with eventual decannulation prior to being discharged to acute …

Tricks of the Trach: Approach to Tracheostomy Patients in the Emergency Department Tricks of the Trach: Approach to Tracheostomy Patients in the Emergency …

ED Common

Dr. Erica Lee reviews approaches to common presentations in tracheostomy patients
presenting to the ED including obstruction, decannulation, bleeding, tracheal stenosis,
and infection. Skip to content. EMOttawa … Decannulation …

[HTML] Investigating the effects of two different pump heads (Centrifugal vs. Roller Pump) on hematological and immunological mechanisms

H Demirtas, E Iriz, CY Demirtas, D Erer, L Oktar… - Nigerian journal of clinical …, 2018

… After achieving sufficient blood pressure and heart rate, CPB was discontinued. Following
decannulation and bleeding control, thoracic and mediastinal drains were inserted, and
sternum and skin incisions were closed, and the patients were transferred to the ICU …

 

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Scholar : ΓΑΣΤΡΟΟΙΣΟΦΑΓΙΚΗ - νέα αποτε

[PDF] Ανάλυση ύπνου και εντοπισμός συμβάντων με χρήση τεχνικών μηχανικής μάθησης.

Ι Ντάκας - 2018

… Αυτό μπορεί να προκληθεί λόγω του πόνου που προκύπτει από φυσιολογικά προβλήματα
όπως η γαστροοισοφαγική παλινδρόμηση, η αρθρίτιδα και μια σειρά από άλλες ιατρικές
παθήσεις. Συγκριμένα παράγοντες όπως ο σακχαρώδης διαβήτης, οι καρδιακές παθήσεις …

 

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Scholar : ΥΠΟΦΥΣΗ ΥΠΟΘΑΛΑΜΟΣ - νέα αποτελέσματα

[PDF] Εφαρμογές διεπαφών εγκέφαλου υπολογιστή.

Θ Μπιλερό - 2018

… Τα κύρια τμήματα του εγκεφάλου είναι ο εγκεφαλικός φλοιός, ο θάλαμος, ο υποθάλαμος,
η παρεγκεφαλίδα και το εγκεφαλικό στέλεχος. Το βάρος του εγκέφαλου … κροταφικός,
νησιδιακός (Rail). Αδένες: υπόφυση, κωνάριο. Μεμβράνες μήνιγγες …

 

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Scholar : ΡΟΧΑΛΗΤΟ - νέα αποτελέσματα

[PDF] Ανάλυση ύπνου και εντοπισμός συμβάντων με χρήση τεχνικών μηχανικής μάθησης.

Ι Ντάκας - 2018

… 2.4 Ηλεκτροεγκεφαλογράφημα .....35 2.5 Ροχαλητό .....38 … Τελειώνουμε το κεφάλαιο
αναλύοντας μιας άλλη διαταραχής αναπνοής, το ροχαλητό …

 

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Scholar : ΒΑΣΗ ΚΡΑΝΙΟΥ - νέα αποτελέσματα

[PDF] Εφαρμογές διεπαφών εγκέφαλου υπολογιστή.

Θ Μπιλερό - 2018

… Οι θέσεις τοποθέτησης τους είναι τυποποιημένες βάση του διεθνούς συστήματος γνωστό
ως 10 … κρανίου του εξεταζόμενου.[3] 1.2.1 Τρόποι καταγραφής … χωρίζει το κρανίο σε δύο
συμμετρικά μέρη ή σε περιοχές που θεωρείται ότι δεν έχουν σχέση με εγκεφαλική λειτουργία …

 

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Scholar : ΑΚΟΥΣΤΙΚΟ - νέα αποτελέσματα

[PDF] Εφαρμογές διεπαφών εγκέφαλου υπολογιστή.

Θ Μπιλερό - 2018

Page 1. 1 ΤΕΧΝΟΛΟΓΙΚΟ ΕΚΠΑΙΔΕΥΤΙΚΟ ΙΔΡΥΜΑ ΗΠΕΙΡΟΥ ΤΜΗΜΑ ΜΗΧΑΝΙΚΩΝ
ΠΛΗΡΟΦΟΡΙΚΗΣ Τ.Ε. ΠΤΥΧΙΑΚΗ ΕΡΓΑΣΙΑ Εφαρμογές διεπαφών εγκέφαλου υπολογιστή
Θανάσης Μπιλέρο Επιβλέπων καθηγητής Αλέξανδρος Τζάλλας Page 2. 2 Page 3. 3 …

 

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Aquaporin-4 Serostatus and Visual Outcomes in Clinically Isolated Acute Optic Neuritis

Background: Aquaporin-4 antibodies (AQP4-Ab) are associated with neuromyelitis optica spectrum disorder (NMOSD) and typically this disorder has a poor visual prognosis as a result of optic neuritis (ON). Our aim was to report the clinical features at onset and final visual outcomes at 6 months of patients with ON who were positive for AQP4-Ab vs. those who were negative for AQP4-Ab. Methods: Retrospective cohort study. AQP4-Ab were tested by indirect immunofluorescence in 57 patients with a first episode of ON. All patients initially were referred for consideration of multiple sclerosis ON (MSON), NMOSD, or any other inflammatory central nervous system disorder during follow-up (41.31 ± 24.32 months). Our patients were diagnosed as having NMOSD, MSON, chronic relapsing inflammatory ON, and single isolated ON. Risk factors associated with visual outcomes of ON patients were assessed through an ordinal regression model. Results: Positive AQP4-Ab were associated with male sex (P = 0.02), earlier age of onset (P = 0.01), and myelitis relapses (P = 0.04). Seronegative group had fewer recurrences of ON than the seropositive group (35% vs 58%, P = 0.14). Patients that were positive for AQP4-Ab did not have worse visual acuity at baseline and after 6 months. However, poor visual acuity during first attack was associated with a worse visual acuity at 6 months (odds ratio = 2.28, 95% CI [1.58–3.28], P = 0.03). Conclusions: At 6 months, positive AQP4-Ab vs negative AQP4-Ab patients no evidence of poorer visual acuity. Lower visual acuity at baseline was associated with poor visual recovery at 6 months. Address correspondence to Edgar Carnero Contentti, Department of Neurology, Hospital Carlos G. Durand, Av Diaz Velez 5044, C1405DCS, Buenos Aires, Argentina. Email: junior.carnero@hotmail.com, ecarnerocontentti@hospitalaleman.com The authors report no conflicts of interest. © 2018 by North American Neuro-Ophthalmology Society

https://ift.tt/2uwHCnS

Diesel oil removal by Serratia sp. W4-01 immobilized in chitosan-activated carbon beads

Abstract

Serratia sp. W4-01 was immobilized in chitosan-activated carbon beads and used for diesel oil removal. The type and concentration of chitosan, activated carbon content, and bead diameter were investigated as factors affecting diesel oil removal. The results showed that 2% (w/v) squid pen chitosan beads modified with 1% activated carbon (w/v) and with a 3-mm diameter had a good spherical shape and strength as well as diesel oil removal capability. The immobilized W4-01 cells removed more than 40% of diesel oil after 7 days when the initial diesel oil concentration was 100 to 400 mg L⁻¹, whereas 29–36% of diesel oil was removed after 14 days when the initial concentration was 800 to 1000 mg L⁻¹. Additionally, the immobilized cells maintained the ability to remove diesel oil over a pH range of 5–11. The addition of a biosurfactant increased the diesel oil removal from 62 to 75%. The reusability tests revealed that the ability of immobilized cells to remove diesel oil was enhanced after reuse, and 50–90% of diesel oil was removed during 2 to 12 reuse cycles. The stability and survival of W4-01 cells was confirmed by scanning electron microscopy and confocal laser scanning microscopy. The results of this study showed the potential use of W4-01 cells immobilized in chitosan-activated carbon beads for future applications in remediating diesel contamination.

https://ift.tt/2L5CPEb

Effects of phosphorus on absorption and transport of selenium in rice seedlings

Abstract

The effects of different concentrations of phosphorus (P) on absorption and transfer of selenium (Se) in rice seedlings were studied by hydroponics experiment. The interaction between iron plaque and phosphorus on absorption and transport of selenium were studied by adding a large amount of iron-induced iron plaque, to provide a theoretical basis for rational application of phosphate fertilizer in the selenium bio-strengthening process of rice. The results showed that phosphorus deficiency may result in the formation of reddish brown iron oxide coating on the root surface of rice. The formation of root iron plaque of rice is related to concentration of phosphorus, and low concentration of phosphorus (0–1.5 mmol L⁻¹) can increase the amount of root iron plaque. Compared P deficiency culture and 2 mmol L⁻¹ P culture, Se content in the shoots and roots decreased by 76 and 47%, respectively. Addition of Fe²⁺ significantly reduced biomass of shoot and had no significant effect on the roots; when the P concentration increased from 0.1 to 0.3 mmol L⁻¹, transfer coefficient of Se decreased. Therefore, both root iron plaques induced by phosphorus deficiency and iron addition have a strong adsorption effect on selenium, which reduces the transport of selenium from the rice roots to the shoots. In the lower range of phosphorus concentration, low phosphorus can promote selenium content of rice shoot, while higher on the contrary. In the practice of rice production, proper management of phosphorus nutrient is of great significance to control selenium content in rice grain.

https://ift.tt/2LhhuEC

Abstracts from the 11th International Symposium on Minimal Residual Disease, 3–5 May 2018, Montpellier, France

https://ift.tt/2mg3lfS

Oral findings in children and adolescents with Prader-Willi syndrome

Abstract

Objective

To assess the significance of changes in the saliva in the etiology of gingivitis and tooth wear in children and adolescents with Prader-Willi syndrome (PWS).

Materials and methods

The study included 80 (2.8–18 years old; 39 girls and 41 boys): 40 in PWS group (mean age 8.0 ± 4.24 years) and 40 in control group (mean age 7.9 ± 4.12 years). General condition, oral para-functional habits, tooth wear (modified TWI), oral hygiene and gingival status (Plaque Index (PLI) and Gingival Index (GI)), localization of gingivitis, and salivary characteristics were assessed. The chi-square test, the Mann-Whitney U test, Spearman's rank correlation, and odds ratio based on logistic regression in a statistical analysis were applied.

Results

Chances of gingivitis were increased by low PLI (odds ratio (OR) = 32.53), low resting salivary flow (OR = 3.96), increased viscosity of saliva (OR = 3.54), and mouth breathing (OR = 8.17). For gingivitis in anterior regions, low PLI (OR = 107.67), low resting (OR = 5.73) and stimulated (OR = 1.86) salivary flow, increased viscosity of saliva (OR = 5.87), mouth breathing (OR = 10.00), and low stimulated salivary flow (OR = 3.18) were observed. Tooth wear rates were increased by teeth grinding (OR = 16.20), mouth breathing (OR = 4.33), increased viscosity of saliva (OR = 11.67) and low resting (OR = 6.07), and stimulated (OR = 4.22) salivary flow.

Conclusions

In PWS, reduced salivary secretion, increased viscosity, of saliva and mouth breathing increase the risk of plaque-induced gingivitis and tooth wear.

Clinical relevance

The prevention and treatment of tooth wear and gingivitis in PWS patients is necessary not only to treat bruxism and mouth breathing but also to limit the influence of negative changes of saliva.

https://ift.tt/2LhpHJ1

Photodynamic and photobiological effects of light-emitting diode (LED) therapy in dermatological disease: an update

Abstract

Benefit deriving from the use of light is known since ancient time, but, only in the last decades of twentieth century, we witnessed the rapid expansion of knowledge and techniques. Light-emitted diode (LED)-based devices represent the emerging and safest tool for the treatment of many conditions such as skin inflammatory conditions, aging, and disorders linked to hair growth. The present work reviews the current knowledge about LED-based therapeutic approaches in different skin and hair disorders. LED therapy represents the emerging and safest tool for the treatment of many conditions such as skin inflammatory conditions, aging, and disorders linked to hair growth. The use of LED in the treatment of such conditions has now entered common practice among dermatologists. Additional controlled studies are still needed to corroborate the efficacy of such kind of treatment.

https://ift.tt/2Jmywzs

Snacking is Common in People with Diabetes Type 1 and Type 2 with Insulin Therapy and Is Not Associated With Metabolic Control or Quality of Life

Exp Clin Endocrinol Diabetes
DOI: 10.1055/a-0631-8813

Objective The aim of this observational study was to analyse snacking pattern and satisfaction with snacking, and to associate snacking patterns with metabolic control and quality of life in people with diabetes type 1 and 2 on insulin therapy. Methods In 2017, 390 people with diabetes were interviewed in a university outpatient department: 132 diabetes type 1 (56.1y, diabetes duration 24.2y, HbA1c 7.0%), 89 diabetes type 2/biphasic insulin (72.8y, diabetes duration 22.0y, HbA1c 7.1%) and 169 diabetes type 2/prandial insulin (66.7y, diabetes duration 20.5y, HbA1c 7.0%). Standardised questionnaires were used to assess eating patterns, satisfaction with snacking, treatment satisfaction and quality of life. Results The far majority snacked regardless of diabetes type and type of insulin therapy (70.5% type 1, 80.9% type 2/biphasic insulin, 74.6% type 2/prandial insulin) and liked to do so or did not mind (type 1 diabetes 79.5%, type 2 diabetes/biphasic insulin 84.8%, type 2 diabetes/prandial insulin 83.5%). Snacking because of recommendations of healthcare professionals was rare (10.8% type 1 diabetes, 8.2% type 2 diabetes/biphasic insulin, 9.4% type 2 diabetes/prandial insulin). Snacking and not snacking participants did not differ in respect to HbA1c, quality of life or treatment satisfaction. Conclusions Snacking seems to be a common habit in individuals with diabetes and most of them like to snack. Snacking is not associated with better or worse metabolic control or quality of life. The decision to snack or not to snack can be left to the individual and integrated into the therapy without danger for the glycaemic control.
[...]

© Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
Table of contents  |  Abstract  |  Full text

https://ift.tt/2ulVyBT

Unraveling molecular targets of bisphenol A and S in the thyroid gland

Abstract

Bisphenol A (BPA) is a well-known endocrine disruptor with several effects on reproduction, development, and cancer incidence, and it is highly used in the plastic industry. Bisphenol S (BPS) was proposed as an alternative to BPA since it has a similar structure and can be used to manufacture the same products. Some reports show that BPA interferes with thyroid function, but little is known about the involvement of BPS in thyroid function or how these molecules could possibly modulate at the same time the principal genes involved in thyroid physiology. Thus, the aims of this work were to evaluate in silico the possible interactions of BPA and BPS with the thyroid transcription factors Pax 8 and TTF1 and to study the actions in vivo of these compounds in zebrafish thyroid gene expression. Adult zebrafish treated with BPA or BPS showed that sodium iodide symporter, thyroglobulin, and thyroperoxidase genes were negatively or positively regulated, depending on the dose of the exposure. Human Pax 8 alignment with zebrafish Pax 8 and Rattus norvegicus TTF1 alignment with zebrafish TTF1 displayed highly conserved regions in the DNA binding sites. Molecular docking revealed the in silico interactions between the protein targets Pax 8 and TTF1 with BPA and BPS. Importance of some amino acids residues is highlighted and ratified by literature. There were no differences between the mean energy values for BPA docking in Pax 8 or TTF1. However, BPS energy values were lower in TTF1 docking compared to Pax 8 values. The number of amino acids on the protein interface was important for Pax 8 but not for TTF1. The main BPA interactions with proteins occurred through Van der Waals forces and pi-alkyl and alkyl interactions, while BPS interactions mainly occurred through carbon hydrogen bonds and conventional hydrogen bonds in addition to Van der Waals forces and pi-alkyl interactions. These data point to a possible interaction of BPA and BPS with Pax 8 and TTF1.

https://ift.tt/2uy9FmR

Factors influencing the effective dose associated with CBCT: a systematic review

Abstract

Introduction

Due to potential impact of the effects of ionizing radiation used in medical and dental examinations on public health in recent years, many studies are being conducted to quantify the radiation dose values, evaluate scanners, and indicate factors that could influence or reduce radiation doses.

Objectives

This study aimed to evaluate, by a systematic review, the factors that influence the effective radiation dose associated with cone beam computed tomography and respective effects, and compared the effective dose of different cone beam computed tomography (CBCT) scanners with similar exposure parameters.

Materials and methods

A search was conducted on five databases from 2007 to 2015.

Results

The search identified 741 abstracts, among which 44 eligible articles were retrieved in full text. Twenty-three studies met the inclusion criteria and were included. Additional copper filter was evaluated in one study, patient size in 2 studies, region of interest in 1 study, use of a thyroid shield in 2 studies, scan angle in 3 studies, exposure time in 10 studies, FOV diameter in 17 studies, FOV height in 17 studies, kV in 16 studies, mA in 18 studies, mAs in 13 studies, voxel in 8 studies, and resolution in 3 studies. When similar exposure parameters were evaluated, it was observed that CBCT scanner with lower effective dose was Kodak® 9000C 3D (mean 21.2 μSv) in selected studies.

Conclusions

Thirteen factors were related to changes in the effective dose emitted by different scanners. More studies are needed to identify the image quality requirements in addition to measure the radiation.

Clinical relevance

Studies that give more information for professionals who request and interpret the exams and for technicians who perform 3D images about effective radiation dose associated with CBCT are necessary.

https://ift.tt/2JlTa2w

Scholar : These new articles for Archives and Manuscripts are available online

The online platform for Taylor & Francis Online content New for Archives and Manuscripts and online now on Taylor & Francis Online: Book Review Moving image and sound collections for archivists Anthea Skinner Pages: 1-2 | DOI: 10.1080/01576895.2018.1464371 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Distribution of metabolic/obese phenotypes and association with diabetes: 5 years’ cohort based on 22,276 elderly

Abstract

Aims

To describe the distribution and changes of different metabolic/obese phenotypes among more than 22,000 male elderly in China, and also explore the association with diabetes incidence.

Methods

A cohort study based on 22,276 male elderly was conducted in Beijing, from 2009 to 2013. Multiple Cox model was used to calculate the relative risk.

Results

There were only 53.8% of total participants who kept the same phenotype for the 5 years. On the whole, participants with metabolically unhealthy phenotypes had higher relative risks (RRs) than those with metabolically healthy phenotypes. RRs for diabetes showed an increasing trend along with metabolic abnormalities (p < 0.001). However, no statistically significant difference was found across different obese status with the same number of metabolic abnormalities. Changes of metabolic/obese status also showed the same trend. Those who had kept metabolic unhealthy had the highest RRs for diabetes incidence, which was higher than those who kept obesity.

Conclusions

Both metabolically healthy obesity and metabolically unhealthy normal weight phenotypes had an increased risk for diabetes incidence, and metabolic abnormalities might have more influence on diabetes than obesity itself. Changes of metabolic/obese status also had an important impact on diabetes incidence.

https://ift.tt/2menLWA

Scholar : Acta Agriculturae Scandinavica, Section B — Soil & Plant Science, Volume 68, Issue 8, November 2018 is now available online on Taylor & Francis Online

The online platform for Taylor & Francis Online content Acta Agriculturae Scandinavica, Section B — Soil & Plant Science, Volume 68, Issue 8, November 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: Original Articles Temperature response of ammonia and greenhouse gas emission from manure amended silty clay soil Suresh Niraula, Shafiqur Rahman & Amitava Chatterjee Pages: 663-677 | DOI: 10.1080/09064710.2018.1459822 Evaluation of hybrid and population cultivars on standard and high-input technology in winter oilseed rape Wenda-Piesik Anna & Hoppe Szymon Pages: 678-689 | DOI: 10.1080/09064710.2018.1460864 Can within field yield variation be explained using horizontal penetrometer resistance and electrical conductivity measurements? Results from three Swedish fields | Elisabeth Bölenius, Johanna Wetterlind & Thomas Keller Pages: 690-700 | DOI: 10.1080/09064710.2018.1464201 The effect of different production systems on the content of micronutrients and trace elements in potato tubers Jadwiga Wierzbowska, Bogumił Rychcik & Arkadiusz Światły Pages: 701-708 | DOI: 10.1080/09064710.2018.1466908 Soil erosion, regulatory aspects and farmer responsibility: assessing cadastral data Jana Poláková, Jaroslava Janků & Martina Nocarová Pages: 709-718 | DOI: 10.1080/09064710.2018.1471158 Biomass, nitrogen and potassium dynamics in hydroponic rose production Daniela Alvarado-Camarillo, Luis A. Valdez-Aguilar, Ana María Castillo-González, Libia I. Trejo-Téllez & Silvia Y. Martínez-Amador Pages: 719-726 | DOI: 10.1080/09064710.2018.1473481 Irrigation with salt water affects growth, yield, fruit quality, storability and marker-gene expression in cherry tomato Mohamed M. El-Mogy, Cecile Garchery & Rebecca Stevens Pages: 727-737 | DOI: 10.1080/09064710.2018.1473482 Leaf gas exchange and water-use efficiency of dry-land wheat genotypes under water stressed and non-stressed conditions Nkhathutsheleni Maureen Tshikunde, Alfred Odindo, Hussein Shimelis & Jacob Mashilo Pages: 738-748 | DOI: 10.1080/09064710.2018.1480729 Release of carbon and nitrogen from fodder radish (Raphanus sativus) shoots and roots incubated in soils with different management history Teng Hu, Jørgen E. Olesen, Bent T. Christensen & Peter Sørensen Pages: 749-756 | DOI: 10.1080/09064710.2018.1480730 Evaluating crude extracts of Monsonia burkeana and Moringa oleifera against Fusarium wilt of tomato Mapula Tshepo Pertunia Hlokwe, Mapotso Anna Kena & Ndivhuwo David Mamphiswana Pages: 757-764 | DOI: 10.1080/09064710.2018.1484946 Hoping to have your article read by anyone, anywhere and at any time? Find out more about publishing open access with Ecosystem Health and Sustainability. To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Raltitrexed Concurrent With Radiotherapy for Elderly Chinese Patients With Squamous Cell Carcinoma of Esophagus

Condition:   Esophagus Squamous Cell Carcinoma
Intervention:   Drug: raltitrexed
Sponsor:   Huai'an First People's Hospital
Not yet recruiting

https://ift.tt/2zxvuZe

Distribution of metabolic/obese phenotypes and association with diabetes: 5 years’ cohort based on 22,276 elderly

Abstract

Aims

To describe the distribution and changes of different metabolic/obese phenotypes among more than 22,000 male elderly in China, and also explore the association with diabetes incidence.

Methods

A cohort study based on 22,276 male elderly was conducted in Beijing, from 2009 to 2013. Multiple Cox model was used to calculate the relative risk.

Results

There were only 53.8% of total participants who kept the same phenotype for the 5 years. On the whole, participants with metabolically unhealthy phenotypes had higher relative risks (RRs) than those with metabolically healthy phenotypes. RRs for diabetes showed an increasing trend along with metabolic abnormalities (p < 0.001). However, no statistically significant difference was found across different obese status with the same number of metabolic abnormalities. Changes of metabolic/obese status also showed the same trend. Those who had kept metabolic unhealthy had the highest RRs for diabetes incidence, which was higher than those who kept obesity.

Conclusions

Both metabolically healthy obesity and metabolically unhealthy normal weight phenotypes had an increased risk for diabetes incidence, and metabolic abnormalities might have more influence on diabetes than obesity itself. Changes of metabolic/obese status also had an important impact on diabetes incidence.

https://ift.tt/2menLWA

Industrial water use, income, trade, and employment: environmental Kuznets curve evidence from 17 Taiwanese manufacturing industries

Abstract

This paper investigated the relationships between industrial water use, income, trade, and employment for 17 Taiwanese industries from 1998 to 2015. We explored cross-sectional dependent unit root, panel cointegration, and causality tests to estimate their long-term relationships and causal nexus. There existed long-term equilibrium relationships among the variables. The long-term elasticity estimates of industrial water use with respect to income, squared income, trade, and employment are 4.27, − 0.15, 0.22, and 0.92, respectively. The results do not confirm an inverted U-shaped environmental Kuznets curve. A unidirectional causal relationship is found between water use and income, and a bidirectional causal relationship is identified between water use and employment. Exports cause industrial water use. As expected, both employment and exports lead to income. Hence, policy makers should promote investment into water efficiency and water recycling. Various governments reward firms for water efficiency and lower consumption without negative long-term effects on economic growth.

https://ift.tt/2Lisodm

Skin toxicity with anti-EGFR monoclonal antibody in cancer patients: a meta-analysis of 65 randomized controlled trials

Abstract

We performed a meta-analysis to fully investigate the skin toxicities of anti-EGFR monoclonal antibody (EGFR-MoAbs) in cancer patients. The relevant studies of the randomized controlled trials (RCTs) in cancer patients treated with EGFR-MoAbs were retrieved and the systematic evaluation was conducted. EMBASE, MEDLINE, and PubMed were searched for articles published till November 2017. The relevant RCTs in cancer patients treated with EGFR-MoAbs were retrieved and the systematic evaluation was conducted. 65 RCTs and 25994 patients were included. The current meta-analysis suggests that the use of EGFR-MoAbs significantly increases the risk of developing all-grade and high-grade skin toxicity, such as rash, hand–foot syndrome, dry skin and oral mucositis. Rash was the most common skin toxicity. Patients receiving nimotuzumab were associated with the least risk of skin toxicity. The risk of high-grade skin toxicity tended to be higher in the study in which the EGFR-MoAbs treatment duration was longer. The available data suggested that the use of EGFR-MoAbs significantly increases the risk of developing skin toxicity. Physicians should be aware of skin toxicity and should monitor cancer patients when receiving EGFR-MoAbs.

https://ift.tt/2NLSVkN

An Atypical HNF4A Mutation Which Does Not Conform to the Classic Presentation of HNF4A-MODY.

Related Articles

An Atypical HNF4A Mutation Which Does Not Conform to the Classic Presentation of HNF4A-MODY.

Case Rep Endocrinol. 2018;2018:1560472

Authors: Spiro AJ, Vu KN, Warnock AL

Abstract
Objective: To present the case of an atypical Hepatocyte Nuclear Factor 4 Alpha (HNF4A) mutation that is not consistent with the classically published presentation of HNF4A-Mature Onset Diabetes of the Young (MODY).
Methods: Clinical presentation and literature review.
Results: A 43-year-old nonobese man was referred to the endocrinology clinic for evaluation of elevated fasting blood glucose (FBG) measurements. Laboratory review revealed prediabetes and hypertriglyceridemia for the previous decade. Testing of autoantibodies for type 1 diabetes was negative. Genetic testing showed an autosomal dominant, heterozygous missense mutation (c.991C>T; p.Arg331Cys) in the HNF4A gene, which is correlated with HNF4A-MODY. Phenotypically, patients with an HNF4A-MODY tend to have early-onset diabetes, microvascular complications, low triglyceride levels, increased birth weight, fetal macrosomia, and less commonly neonatal hyperinsulinemic hypoglycemia. The patient did not demonstrate any of these features but instead presented with late-onset diabetes, an elevated triglyceride level, and a normal birth weight.
Conclusion: Our patient likely represents an atypical variant of HNF4A-MODY with a milder clinical presentation. Patients with atypical, less-severe presentations of HNF4A-MODY may be largely undiagnosed or misdiagnosed, but identification is important due to implications for treatment, pregnancy, and screening of family members.

PMID: 29998026 [PubMed]

https://ift.tt/2utW1B2

Obesogenic Endocrine Disrupting Chemicals: Identifying Knowledge Gaps

Publication date: Available online 13 July 2018

Source: Trends in Endocrinology & Metabolism

Author(s): Almudena Veiga-Lopez, Yong Pu, Jeremy Gingrich, Vasantha Padmanabhan

Endocrine disrupting chemicals (EDCs) are compounds that are part of everyday consumer products and industrial manufacturing processes. EDCs can interfere with the endocrine system, including the adipose tissue. Accumulating evidence from epidemiological, animal, and in vitro studies demonstrates that EDCs can alter body weight, adipose tissue expansion, circulating lipid profile, and adipogenesis, with some resulting in transgenerational effects. These outcomes appear to be mediated through multiple mechanisms, from nuclear receptor binding to epigenetic modifications. A better understanding of the signaling pathways via which these EDCs contribute to an obesogenic phenotype, the interaction amongst complex mixtures of obesogenic EDCs, and the risks they pose relative to the obesity epidemic are still needed for risk assessment and development of prevention strategies.

https://ift.tt/2L5M8nz