Scholar : ΓΛΩΣΣΙΤΙΣ - νέα αποτελέσματα

[PDF] Sextuple Tumors in Head and Neck Area: Evidence of Field Cancerization

CB Nelem-Colturato, PM Cury, TM Pereira, IS Cosso… - Case Reports in Pathology, 2018

… which is the fifth malignant tumor. Forty-six months after the diagnostic, the first
malignancy the patient developed symptomatic lesions in base of tongue was
diagnosed as nonspecific chronic glossitis. The tissue adjacent to the …

Viral Infections

SW Wassilew - Pigmented Ethnic Skin and Imported Dermatoses, 2018

… Open image in new window Fig. 7.7. Fig. 7.7 Gingivostomatitis herpetica with
accompanying glossitis and cheilitis. Recurrences arise in 30–50% of the cases. Possible
triggers are fever, ultraviolet radiation, trauma, emotional stress, and others …

33 Chylous ascites

E Shmueli - Diagnosis and Treatment in Internal Medicine, 2018

[PDF] PENGARUH SUBTITUSI TEPUNG BERAS MERAH DAN PROPORSI LEMAK (MARGARIN DAN MENTEGA) TERHADAP MUTU ORGANOLEPTIK RICH BISCUIT

N APRIL SINTIA, N Astuti - Jurnal Tata Boga, 2018

… Vitamin B kompleks berperan dalam mencegah terjadinya penyakit
beri-beri, neuropati perifer, keluhan mudah capai, anoreksia, anemia,
cheilosis, glossitis, seborrhea, pelagra, edema hingga degenerasi sistem …

[PDF] Submitted: 19 April 2017 Accepted: 23 July 2018

L Olcay, Ş Ünal, H Onay, E Erdemli, A Öztürk, D Billur…

Page 1. uncorrected proof 1 Research TJH-2017-0160.R4 Submitted: 19 April 2017
Accepted: 23 July 2018 Both granulocytic and non-granulocytic blood cells are affected
in patients with severe congenital neutropenia and their non-neutropenic family …

 

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Scholar : intitle:Bioprinting - νέα αποτελέσματα

Perspective:"Universal" bioink technology for advancing extrusion bioprinting-based biomanufacturing

A Skardal - 2018

Bioprinting has emerged as a flexible tool in regenerative medicine with potential in
a variety of applications, including eventual large-scale biomanufacturing of tissue
products. One of the major problems that the field of bioprinting, and more broadly …

PO-103: A Primary Study for Bioprinting of Human Liver

Y Mao, H Yang - 춘· 추계 학술대회 (KASL), 2018

This study is aim to construct human liver tissue structure using 3D biological printing
technology. We used the characteristics of stem cell differentiation and cell 3D
printing technology to investigate the progress of stem cell differentiation, 3D print ing …

Click Chemistry-Based Injectable Hydrogels and Bioprinting Inks for Tissue Engineering Applications

J Gopinathan, I Noh - Tissue Engineering and Regenerative Medicine

Background: The tissue engineering and regenerative medicine approach require
biomaterials which are biocompatible, easily reproducible in less time,
biodegradable and should be able to generate complex three-dimensional (3D) …

 

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Scholar : Laryngotracheal reconstruction - νέα αποτελ

Cartilage Tissue Engineering

HJ Faust, Q Guo, JH Elisseeff - Principles of Regenerative Medicine, 2019

… Tissue Engineering for Cartilage Repair. To overcome the treatment obstacles of
available surgical options for cartilage repair, the reconstruction of cartilage using
tissue engineering techniques has attracted tremendous attention …

[PDF] Saudi Journal of Oral and Dental Research (SJODR) ISSN 2518-1300 (Print)

RS Prathigudupu, RVC Tiwari, P Mathew, B Roy…

… Planned reconstruction schedule is required to achieve maximum, satisfactory
function and appearance as unnecessary delay in surgery … concern in patients
with maxillofacial trauma (gunshot wounds, facial fractures, cervical spine …

 

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Scholar : ΡΙΝΙΚΟ ΔΙΑΦΡΑΓΜΑ - νέα αποτελέσματα

[PDF] Efeitos da prática do Lien Ch'i nos escores psicológicos (DASS) em escolares

A Barai, JGQ Cabanillas, TC Flores, RMZ de Moraes - Cadernos UniFOA, 2018

… Supõe-se que tenha sido escrito na época dos Reinos Combatentes (475
aC a 221 aC) e publicado no período de (221 aC a 220 … Especula-se que
o ajuste da respiração somado à execução dos exercícios podem interferir …

 

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Scholar : Laryngomalacia - νέα αποτελέσματα

[PDF] SMITH LEMLI OPITZ SYNDROME TYPE 2 ASSOCIATED WITH SEVERE LARYNGOMALACIA, TRACHEOESOPHAGEAL FISTULA AND PYLORIC STENOSIS. A …

G Garima, K Deepak, J Urmila - PARIPEX-INDIAN JOURNAL OF RESEARCH, 2018

Abstract Smith Lemli Opitz syndrome is a common inborn error affecting cholesterol
synthesis. Association with tracheoesophageal fistula, laryngomalacia and pyloric
stenosis together has not been found in literature. It is a treatable genetic defect; a …

 

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Scholar : Undersea "Hyperbaric Medicine" - νέα αποτελέσματα

Hyperbaric oxygen treatment for the management of radiation‐induced xerostomia

S Sherlock, M Way, A Tabah - Journal of Medical Imaging and Radiation Oncology, 2018

… 1 Hyperbaric Medicine Unit, Royal Brisbane and Women's Hospital, Brisbane,
Queensland, Australia 2 Anaesthesia and Perioperative Services, Royal
Brisbane … It is defined by the Undersea and Hyperbaric Medical Society (UHMS) …

 

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Scholar : ωτα - νέα αποτελέσματα

[PDF] A Villafranchian Hipparion-Bearing Mammal Fauna from Sésklo (E. Thessaly, Greece): Implications for the Question of Hipparion–Equus Sympatry in Europe

A Athanassiou

Page 1. quaternary Article A Villafranchian Hipparion-Bearing Mammal Fauna from
Sésklo (E. Thessaly, Greece): Implications for the Question of Hipparion–Equus
Sympatry in Europe Athanassios Athanassiou 1,2 1 Ephorate …

 

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Scholar : Cricotracheal resection - νέα αποτελέσματα

Reflex regulation of breathing by the paratrigeminal nucleus via multiple bulbar circuits

AK Driessen, MJ Farrell, M Dutschmann, D Stanic… - Brain Structure and Function, 2018

… containing 5 µl of CT-B594 (2 mg/ml in 0.9% saline) was inserted into the laryngeal lumen,
distal to the cricotracheal ligament, ensuring … All physiological experiments described below
were conducted in animals following bilat- eral resection of the recurrent laryngeal nerves …

 

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Statistical evaluation of the geochemical variability in overbank sediments in Spain

Abstract

The overall objective of this study is to estimate, detect and specify the main sources of variance which affect the contents of the different elements in overbank sediments across Spain. These sources of variance were assessed and compared by means of a series of analyses of variance (ANOVAs), by regarding two parameters: their significance and their contribution to the total variance. Overbank sediments, sampled in erosion banks, were studied in several locations, in basins which drain different types of geological backgrounds and land uses (urban, mining, agricultural or pristine) across the Iberian Peninsula. Forty-eight elements (mostly in the < 63 μm fraction) were analysed by ICP-OES, ICP-MS and INAA. After an isometric log ratio (ilr) transformation of the data, three ANOVA analyses were performed considering three perspectives: (1) local scale, (2) regional scale: within-profile perspective and (3) regional scale: inter-profile perspective. On a local scale, it was observed that the variability of rare earth elements (REE) depends mostly on the grain size and that heavy metals are also influenced by depth. In the analysis carried out on a regional scale, from a within-profile perspective, depth and duplicates do not influence significantly the variability of the element contents. Finally, from an inter-profile perspective, the selected sources of variance were land use and provenance, whose significance is the highest. While grain size and the selection of depth are of crucial importance in the final results, on local studies, land use and provenance are the ones that influence the most the composition of sediments in regional studies.

https://ift.tt/2BsrZ7F

Silvery hair with dyschromatosis: Griscelli syndrome Type 3 or Familial gigantic melanocytosis

Journal of Cutaneous Pathology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2w0meJb

Elevated total serum IgE in vitiligo might be protective for other autoimmune diseases

British Journal of Dermatology, EarlyView.


https://ift.tt/2N5SZez

MiR‐146a‐5p correlates with clinical efficacy in patients with psoriasis treated with the tumour necrosis factor‐alpha inhibitor adalimumab

British Journal of Dermatology, EarlyView.


https://ift.tt/2Pr9ymr

Genotype–phenotype correlation, gonadal malignancy risk, gender preference, and testosterone/dihydrotestosterone ratio in steroid 5-alpha-reductase type 2 deficiency: a multicenter study from Turkey

Abstract

Background

Studies regarding genetic and clinical characteristics, gender preference, and gonadal malignancy rates for steroid 5-alpha-reductase type 2 deficiency (5α-RD2) are limited and they were conducted on small number of patients.

Objective

To present genotype–phenotype correlation, gonadal malignancy risk, gender preference, and diagnostic sensitivity of serum testosterone/dihydrotestosterone (T/DHT) ratio in patients with 5α-RD2.

Materials and methods

Patients with variations in the SRD5A2 gene were included in the study. Demographic characteristics, phenotype, gender assignment, hormonal tests, molecular genetic data, and presence of gonadal malignancy were evaluated.

Results

A total of 85 patients were included in the study. Abnormality of the external genitalia was the most dominant phenotype (92.9%). Gender assignment was male in 58.8% and female in 29.4% of the patients, while it was uncertain for 11.8%. Fourteen patients underwent bilateral gonadectomy, and no gonadal malignancy was detected. The most frequent pathogenic variants were p.Ala65Pro (30.6%), p.Leu55Gln (16.5%), and p.Gly196Ser (15.3%). The p.Ala65Pro and p.Leu55Gln showed more undervirilization than the p.Gly196Ser. The diagnostic sensitivity of stimulated T/DHT ratio was higher than baseline serum T/DHT ratio, even in pubertal patients. The cut-off values yielding the best sensitivity for stimulated T/DHT ratio were ≥ 8.5 for minipuberty, ≥ 10 for prepuberty, and ≥ 17 for puberty.

Conclusion

There is no significant genotype–phenotype correlation in 5α-RD2. Gonadal malignancy risk seems to be low. If genetic analysis is not available at the time of diagnosis, stimulated T/DHT ratio can be useful, especially if different cut-off values are utilized in accordance with the pubertal status.

https://ift.tt/2MAYaWP

Impaired bone matrix glycoprotein pattern is associated with increased cardio-metabolic risk profile in patients with type 2 diabetes mellitus

Abstract

Purpose

Osteopontin (OPN), osteoprotegerin (OPG) and osteocalcin (OC) are matrix glycoproteins which mediate bone mineralization; moreover, their effects on glucose/insulin homeostasis have recently been demonstrated. Higher circulating OPN and OPG levels have been associated with the presence of insulin resistance, atherosclerosis and coronary heart disease. No data are available on contextual changes of these markers in type 2 diabetes mellitus (T2DM). Therefore, aims of this study were to evaluate serum OPN, OPG and OC levels in T2DM patients and their clinical correlates.

Methods

We recruited 83 consecutive T2DM patients referring to our diabetes outpatient clinics at Sapienza, University of Rome, and 71 non-diabetic sex and age-comparable subjects as a control group. Study population underwent metabolic characterization and carotid ultrasound for intima–media thickness measurement. Plasma OPN, OPG and OC were measured by MILLIPLEX Multiplex Assays Luminex.

Results

T2DM patients had significantly higher circulating OPN and OPG levels than controls (14.3 ± 13.6 vs 10.6 ± 13.7 ng/ml p < 0.001, 0.70 ± 0.60 vs 0.54 ± 4.1 ng/ml, p = 0.02) while OC levels were similar in the two cohorts (6.35 ± 5.8 vs 7.80 ± 7.0 ng/ml, p = n.s). OPN and OPG positively correlated with greater systolic blood pressure (SBP) values, HOMA-IR and HOMA-β, and with the presence of dyslipidemia and carotid atherosclerosis. The association between greater OPN and OPG levels and SBP was independent from possible confounders (both p = 0.01).

Conclusions

Circulating OPN and OPG levels are increased in T2DM patients and identify a particularly unfavourable metabolic profile, mostly expressed by higher SBP. Bone peptides may represent novel markers of vascular stress and accelerated atherosclerosis in diabetes, constituting a possible tool for cardiovascular risk stratification in diabetes.

https://ift.tt/2BvBVx8

Completion lymphadenectomy should not necessarily be recommended after a positive sentinel lymph node biopsy

Clinical and Experimental Dermatology, EarlyView.


https://ift.tt/2Mq6qJR

Secukinumab‐induced paradoxical pustular psoriasis

Clinical and Experimental Dermatology, EarlyView.


https://ift.tt/2wl0J5g

Photoperiod and thyroid hormone regulate expression of L‐Dopachrome tautomerase (Dct), a melanocyte stem‐cell marker, in tanycytes of the ovine hypothalamus

Journal of Neuroendocrinology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2PnTm5v

Fluorene oxidation by solar-driven photo-Fenton process: toward mild pH conditions

Abstract

Polycyclic aromatic hydrocarbons (PAHs) are on the list of priority pollutants to be eliminated from the environment due to their carcinogenic and mutagenic action, chemical stability, and resistance to biodegradation. The aim of this study was to evaluate the degradation of fluorene, a well-known PAH, in aqueous solutions (0.03 and 0.08 mg L⁻¹), by means of a solar-driven conventional (PF) and modified photo-Fenton mediated by ferrioxalate complexes (PFF). Photolysis was also employed for comparison purposes. PF reaction was evaluated at different pH values (2.8, 3.5, and 4.0) and iron concentrations (2, 5, 10, and 20 mg L⁻¹). On the other hand, PFF studies were conducted at mild pH conditions (4.0, 5.0, and 6.0) and iron content of 2 mg L⁻¹, keeping initial iron/oxalate molar ratio at 1:3. In both PF and PFF, the initial hydrogen peroxide/iron molar ratio was maintained at 5. In the presence of methanol as cosolvent for fluorene dissolution, the PF reaction was hampered and no consumption of H₂O₂ was observed during the reaction carried out at constant pH (2.8). This led to low degradation rates, similar to those achieved by photolysis. Under the same pH but using acetonitrile as cosolvent for fluorene dissolution, fluorene degradation was found to be proportional to the iron content used in the PF experiments. On the other hand, at an invariable iron concentration of 5 mg Fe²⁺ L⁻¹, the increase in pH was accompanied by a decrease in the molar fraction of the most photoactive iron complex (FeOH²⁺) and ferric hydroxides precipitation, leading to a reduction in the fluorene degradation rate. With regard to the PFF tests, similar fluorene degradation performance was achieved at pH 4 and 5, while at pH 6 iron precipitation became relevant and the degradation rate was slightly slower. PFF has shown to be more efficient than the PF under the same pH (4) and iron concentration (2 mg L⁻¹). Moreover, even at near neutral pH (6), fluorine degradation was shown to be feasible by using ferrioxalate complexes.

https://ift.tt/2Naounq