Scholar : Molecular Medicine Reports - Volume:18 Number:5

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TABLE OF CONTENTS November-2018 Volume 18 Issue 5

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Roles of endoplasmic reticulum stress and autophagy on H2O2‑induced oxidative stress injury in HepG2 cells Zhiming Wu, Huangen Wang, Sunyang Fang, Chaoyang Xu View Abstract ❯
Anti‑breast cancer activity of selected 1,3,5‑triazines via modulation of EGFR‑TK Weixin Yan, Yiyang Zhao, Jianrong He View Abstract ❯
Bioinformatics analyses of significant genes, related pathways and candidate prognostic biomarkers in glioblastoma Lingqi Zhou, Hai Tang, Fang Wang, Lizhi Chen, Shanshan Ou, Tong Wu, Jie Xu, Kaihua Guo View Abstract ❯
Network analysis of membranous glomerulonephritis based on metabolomics data Amir Taherkhani, Shiva Kalantari, Afsaneh Arefi Oskouie, Mohsen Nafar, Mohammad Taghizadeh, Koorosh Tabar View Abstract ❯
Effect of chemokine CC ligand 2 (CCL2) on α‑synuclein‑induced microglia proliferation and neuronal apoptosis Lijun Zhang, Pengju Ma, Qingkai Guan, Lei Meng, Linlin Su, Lina Wang, Bin Yuan View Abstract ❯
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury Yang Liu, Wanting Cao, Xiangbo Kong, Jie Li, Xueying Chen, Yaping Ge, Wanzhen Zhong, Silian Fang View Abstract ❯
Comprehensive analysis of multi Ewing sarcoma microarray datasets identifies several prognosis biomarkers Xuqing Yin, Jiubo Sun, Haiyang Zhang, Shuai Wang View Abstract ❯
Long non‑coding RNA ferritin heavy polypeptide 1 pseudogene 3 controls glioma cell proliferation and apoptosis via regulation of the microRNA‑224‑5p/tumor protein D52 axis Yongqiang Zhang, Ying Li, Jing Wang, Ping Lei View Abstract ❯
Distribution and prognostic value of tumor‑infiltrating T cells in breast cancer Shaoda Meng, Li Li, Meiling Zhou, Wanjie Jiang, Heng Niu, Kunxian Yang View Abstract ❯
BACE1 gene silencing alleviates isoflurane anesthesia‑induced postoperative cognitive dysfunction in immature rats by activating the PI3K/Akt signaling pathway Ying‑Bin Wang, Jian‑Qin Xie, Wei Liu, Rong‑Zhi Zhang, Sheng‑Hui Huang, Yan‑Hong Xing View Abstract ❯
Genetic mutation of familial dilated cardiomyopathy based on next‑generation semiconductor sequencing Xin‑Fu Lin, Jie‑Wei Luo, Gui Liu, Yao‑Bin Zhu, Zhao Jin, Xing Lin View Abstract ❯
Combination of pristimerin and paclitaxel additively induces autophagy in human breast cancer cells via ERK1/2 regulation Younju Lee, Jinuk Na, Myung Sun Lee, Eun Young Cha, Ji Young Sul, Jun Beom Park, Jin Sun Lee View Abstract ❯
Pharmacological basis for application of scutellarin in Alzheimer's disease: Antioxidation and antiapoptosis Xinyu Hu, Shanshan Teng, Jiawei He, Xiaoqi Sun, Mingzhao Du, Ling Kou, Xiaofeng Wang View Abstract ❯
Elevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease Chunshuang Xu, Guili Liu, Huihui Ji, Weihua Chen, Dongjun Dai, Zhongming Chen, Dongsheng Zhou, Lei Xu, Haochang Hu, Wei Cui, Lan Chang, Qin Zha, Liping Li, Shiwei Duan, Qinwen Wang View Abstract ❯
Effect of emodin on T cell subsets in NOD mice with NaI‑induced experimental autoimmune thyroiditis Huaqin Sun, Zhipeng Ye, Ning Li, Fa Jin, Jiuliang Yan, Keren Wu View Abstract ❯
Modular bioinformatics analysis demonstrates that a Toll‑like receptor signaling pathway is involved in the regulation of macrophage polarization Biao Ma, Yang Yang, Zhituo Li, Dali Zhao, Weihui Zhang, Yanfeng Jiang, Dongbo Xue View Abstract ❯
Cytoprotective effects of the medicinal herb Astragalus membranaceus on lipopolysaccharide‑exposed cells Xian Wu, Wei Zhou, Qingshuang Wei, Peng Chen, Yan Li View Abstract ❯
Protein phosphatase 2A regulates the p38 signaling pathway to affect the migration of astrocytes Lijun Zhang, Pengju Ma, Qingkai Guan, Lei Meng, Linlin Su, Lina Wang, Jianhua Zhao, Sibei Ji View Abstract ❯
Deletion of poly(ADP‑ribose) polymerase-1 changes the composition of the microbiome in the gut András Vida, Gábor Kardos, Tünde Kovács, Balázs L. Bodrogi, Péter Bai View Abstract ❯
Amino acid starvation promotes podocyte autophagy through mammalian target of rapamycin inhibition and transcription factor EB activation Yuanhan Chen, Xingchen Zhao, Jiaxin Li, Li Zhang, Ruizhao Li, Hong Zhang, Ruyi Liao, Shuangxin Liu, Wei Shi, Xinling Liang View Abstract ❯
Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes Hangyu Tian, Dan Yu, Yan Hu, Pan Zhang, Yang Yang, Qiang Hu, Ming Li View Abstract ❯
Downregulation of FOXK2 is associated with poor prognosis in patients with gastric cancer Xi Liu, Xiaodong Wei, Wei Niu, Dong Wang, Bo Wang, Hao Zhuang View Abstract ❯
Molecular pathogenesis involved in human idiopathic pulmonary fibrosis based on an integrated microRNA‑mRNA interaction network Lijing Wang, Wei Huang, Lemeng Zhang, Qiong Chen, Hongjun Zhao View Abstract ❯
CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4‑activated MEK/ERK and PI3K/AKT pathways Yongyang Tian, Hong Yin, Xi Deng, Beichuan Tang, Xianjun Ren, Tao Jiang View Abstract ❯
Dicer affects cisplatin‑mediated apoptosis in epithelial ovarian cancer cells Xi Wang, Hui Chen, Yiping Wen, Xiaoxin Yang, Qing Han, Ping Jiang, Zaiju Huang, Jing Cai, Zehua Wang View Abstract ❯
Streptozotocin‑induced diabetic mice exhibit reduced experimental choroidal neovascularization but not corneal neovascularization Gaoqin Liu, Lei Chen, Qinhua Cai, Hongya Wu, Zhigang Chen, Xueguang Zhang, Peirong Lu View Abstract ❯
Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury Dandan Li, Weiying Ren, Zhilong Jiang, Lei Zhu View Abstract ❯
Estrogen restricts the apoptosis of endometrial stromal cells by promoting TSLP secretion Hui‑Li Yang, Kai‑Kai Chang, Jie Mei, Wen‑Jie Zhou, Li‑Bing Liu, Li Yao, Yi Meng, Ming‑Yan Wang, Si‑Yao Ha, Zhen‑Zhen Lai, Jiang‑Feng Ye, Da‑Jin Li, Ming‑Qing Li View Abstract ❯
Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen‑glucose deprivation Wen‑Bo Yu, Liang Cao, Yan‑Yin Zhao, Wei Xiao, Bao‑Guo Xiao View Abstract ❯
FKBP11 protects intestinal epithelial cells against inflammation‑induced apoptosis via the JNK‑caspase pathway in Crohn's disease Xiaotong Wang, Xiaopeng Cui, Chuanwu Zhu, Ming Li, Juan Zhao, Zhongyi Shen, Xiaohang Shan, Liang Wang, Han Wu, Yanting Shen, You Ni, Dongmei Zhang, Guoxiong Zhou View Abstract ❯
Two Paired Box 6 mutations identified in Chinese patients with classic congenital aniridia and cataract Ying Lin, Hongbin Gao, Yi Zhu, Chuan Chen, Tao Li, Bingqian Liu, Cancan Lyu, Ying Huang, Haichun Li, Qingxiu Wu, Chenjin Jin, Xiaoling Liang, Xinhua Huang, Lin Lu View Abstract ❯
Using Illumina Infinium HumanMethylation 450K BeadChip to explore genome‑wide DNA methylation profiles in a human hepatocellular carcinoma cell line Ning Sun, Jialin Zhang, Chengshuo Zhang, Yue Shi, Bochao Zhao, Ao Jiao, Baomin Chen View Abstract ❯
Adoptive transfer of xenoantigen‑stimulated T cell receptor Vβ‑restricted human regulatory T cells prevents porcine islet xenograft rejection in humanized mice Xi Jin, Min Hu, Lina Gong, Huifang Li, Yan Wang, Ming Ji, Hong Li View Abstract ❯
Protective effect of berberine on aconite‑induced myocardial injury and the associated mechanisms Xueyan Chen, Huicai Guo, Qing Li, Yu Zhang, Huanlong Liu, Xiaofei Zhang, Kerang Xie, Zhongning Zhu, Qingfeng Miao, Suwen Su View Abstract ❯
Platelet‑rich fibrin exudate promotes the proliferation and osteogenic differentiation of human periodontal ligament cells in vitro Xiaoju Li, Huixiao Yang, Zijiian Zhang, Zhonghai Yan, Huling Lv, Yan Zhang, Bin Wu View Abstract ❯
Role of the Rho/ROCK signaling pathway in the protective effects of fasudil against acute lung injury in septic rats Yu Wang, Xiaofeng Wang, Wei Liu, Lichun Zhang View Abstract ❯
Identification of key genes and associated pathways in KIT/PDGFRA wild‑type gastrointestinal stromal tumors through bioinformatics analysis Wen‑Jie Wang, Hong‑Tao Li, Jian‑Ping Yu, Yu‑Min Li, Xiao‑Peng Han, Peng Chen, Wen‑Wen Yu, Wei‑Kai Chen, Zuo‑Yi Jiao, Hong‑Bin Liu View Abstract ❯
Protective effects of taurine against inflammation, apoptosis, and oxidative stress in brain injury Xiaoli Niu, Simin Zheng, Hongtao Liu, Siyuan Li View Abstract ❯
Complement depletion with cobra venom factor alleviates acute hepatic injury induced by ischemia‑reperfusion Bing Wang, Hua Xu, Jian Li, Hong‑Mei Gao, Ying‑Hong Xing, Zhu Lin, Hong‑Jie Li, Yong‑Qiang Wang, Shu‑Hua Cao View Abstract ❯
Aldehyde dehydrogenase activity in cryopreserved cord blood cells for quality assessment prior to transplantation Junko Ikemoto, Satoshi Yoshihara, Tamami Kobayashi, Shunro Kai, Yoshihiro Fujimori View Abstract ❯
Theanine, an antitumor promoter, induces apoptosis of tumor cells via the mitochondrial pathway Yinqiang Xin, Peiling Ben, Qi Wang, Yanyan Zhu, Zhimin Yin, Lan Luo View Abstract ❯
Expression and clinical significance of ubiquitin‑specific‑processing protease 34 in diffuse large B‑cell lymphoma Chunyao Li, Lanshan Huang, Huiping Lu, Wei Wang, Gang Chen, Yongyao Gu, Qianping Zhou, Zhigang Peng, Zhenbo Feng View Abstract ❯
Epigallocatechin‑3‑gallate protects against secondary osteoporosis in a mouse model via the Wnt/β‑catenin signaling pathway Jiancheng Xi, Qinggui Li, Xiaobo Luo, Jinlong Li, Lixin Guo, Haibin Xue, Guangsen Wu View Abstract ❯
miRNA‑328 overexpression confers cisplatin resistance in non‑small cell lung cancer via targeting of PTEN Chunmei Wang, Shijun Wang, Feng'e Ma, Weidan Zhang View Abstract ❯
Silencing of perilipin by short hairpin RNA inhibits proliferation and induces apoptosis in liposarcoma cells Ling‑Xin Meng, Yu‑Xiu Zheng, Mao‑Lei He, Xiao‑Ming Zhou, Shu‑Yan Sun, Zhao‑Jun Ding, Qin Meng, Bing‑Cheng Li, Yan‑Wei Sun View Abstract ❯
Protection of insulin‑like growth factor 1 on experimental peripheral neuropathy in diabetic mice Hua Wang, Hao Zhang, Fuming Cao, Jiaping Lu, Jin Tang, Huizhi Li, Yiyun Zhang, Bo Feng, Zhaosheng Tang View Abstract ❯
Bafilomycin A1 alleviates depression‑like symptoms in chronic unpredictable mild stress rats Zhijian Wang, Shengbing Liu, Weiwei Pan, Yanjun Guo, Zhongfei Shen View Abstract ❯
Huwe1 is a novel mediator of protection of neural progenitor L2.3 cells against oxygen‑glucose deprivation injury Xiaoqin Jiang, Jiyun Yang, Hedong Li, Yi Qu, Wenming Xu, Haiyan Yu, Yu Tong View Abstract ❯
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway Zhen Mu, Qing Sun View Abstract ❯
Analysis of virulence diversity of 73 Helicobacter pylori strains isolated in Guizhou province, China Lin Yin, Fang Liu, Changcheng Guo, Qiong Wang, Ke Pan, Liangbi Xu, Yan Xiong, Yingting Chen, Zhenghong Chen View Abstract ❯
miR‑3120‑5p acts as a diagnostic biomarker in non‑small cell lung cancer and promotes cancer cell proliferation and invasion by targeting KLF4 Hongwei Xu, Quan Wen View Abstract ❯
Association between the methylation of six apoptosis‑associated genes with autism spectrum disorder Yuanzhi Zhao, Cong Zhou, Hang Yu, Wenwu Zhang, Fang Cheng, Haihang Yu, Dongsheng Zhou, Bin Li, Jing Liu, Jie Dai, Jie Zhong, Min Chen, Tianyi Huang, Ranran Pan, Shiwei Duan, Zhenyu Hu View Abstract ❯
Inhibition of CCL19 benefits non‑alcoholic fatty liver disease by inhibiting TLR4/NF‑κB‑p65 signaling Jiajing Zhao, Yingjue Wang, Xi Wu, Ping Tong, Yaohan Yue, Shurong Gao, Dongping Huang, Jianwei Huang View Abstract ❯
Application of medical adhesive inhibits intimal hyperplasia involving the downregulation of ERK1/2 and eNOS levels Shoudong Chai, Yang Yu, Haiming Li, Mingxin Gao, Bo Li , Chengxiong Gu View Abstract ❯
Post‑transplant lymphoproliferative disorder in hematopoietic stem cell transplant patients: A single center retrospective study between 2005 and 2012 Joana Marinho‑Dias, João Lobo, Rui Henrique, Inês Baldaque, Carlos Pinho‑Vaz, Luísa Regadas, Rosa Branca, Fernando Campilho, António Campos Jr, Rui Medeiros, Hugo Sousa View Abstract ❯
Sevoflurane‑induced neurotoxicity is driven by OXR1 post‑transcriptional downregulation involving hsa‑miR‑302e Leilei Yang, Qian Shen, Yanqiong Xia, Xueheng Lei, Jian Peng View Abstract ❯
Attenuated endothelial function is associated with decreased endothelial progenitor cells and nitric oxide in premenopausal diabetic women Juan Liu, Da‑Jun Hu, Huiyang Yan, Jianbin Liu, Xixong Ai, Zi Ren, Haitao Zeng, Hao He, Zhen Yang View Abstract ❯
Ursolic acid alleviates inflammation and against diabetes‑induced nephropathy through TLR4‑mediated inflammatory pathway Jian Li, Nan Li, Shuangtong Yan, Minyan Liu, Banruo Sun, Yanhui Lu, Yinghong Shao View Abstract ❯
SFRP5 serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells Jiadela Teliewubai, Hongwei Ji, Yuyan Lu, Bin Bai, Shikai Yu, Chen Chi, Yawei Xu, Yi Zhang View Abstract ❯
Immunization with lentiviral vector‑modified dendritic cells encoding ubiquitinated hepatitis B core antigen promotes Th1 differentiation and antiviral immunity by enhancing p38 MAPK and JNK activation in HBV transgenic mice Shenglan Dai, Xiaohua Chen, Yongsheng Yu, Guoqing Zang, Zhenghao Tang View Abstract ❯
Molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in H9c2 cells Shu‑Chun Kuo, Yingxiao Li, Yung‑Ze Cheng, Wei‑Jing Lee, Juei‑Tang Cheng, Kai‑Chun Cheng View Abstract ❯
Structure‑activity associations in novel farrerol derivatives with vasorelaxant properties Xiaomin Hou, Xiaojiang Qin, Qingshan Li View Abstract ❯
Sarcomatoid carcinoma of the pancreas: A case report and review of the literature Yingjun Xie, Yien Xiang, Dan Zhang, Xiaoxiao Yao, Jiyao Sheng, Yongsheng Yang, Xuewen Zhang View Abstract ❯
Long noncoding RNA LINC00978 promotes cell proliferation and invasion in non‑small cell lung cancer by inhibiting miR‑6754‑5p Xinlei Li, Yang Ren, Tie Zuo View Abstract ❯
Acute stimulatory effect of tumor necrosis factor on the basolateral 50 pS K channels in the thick ascending limb of the rat kidney Guoyan Zhang, Shiliang Gui, Weiqun Wang, Dexin Meng, Qingmin Meng, Haiyan Luan, Rixin Zhao, Jiatian Zhang, Hongyu Sui View Abstract ❯
Silencing of pantothenate kinase 2 reduces endothelial cell angiogenesis Francesca Pagani, Akansha Trivedi, Deepak Khatri, Daniela Zizioli, Emirena Garrafa, Stefania Mitola, Dario Finazzi View Abstract ❯
miR‑501‑3p sensitizes glioma cells to cisplatin by targeting MYCN Chuan‑Gang Zhang, Fan Yang, Yan‑Hua Li, Yan Sun, Xue‑Jian Liu, Xia Wu View Abstract ❯
Celastrol inhibits glucocorticoid‑induced osteoporosis in rat via the PI3K/AKT and Wnt signaling pathways Jiancheng Xi, Qinggui Li, Xiaobo Luo, Yipeng Wang, Jinlong Li, Lixin Guo, Guangsen Wu View Abstract ❯
LIMD2 targeted by miR‑34a promotes the proliferation and invasion of non‑small cell lung cancer cells Fei Wang, Zhaoguo Li, Lei Xu, Yongchao Li, Yi Li, Xingbo Zhang, Yue Wang, Dazhong Liu View Abstract ❯
[Retracted] BIRC5 is a novel target of peroxisome proliferator‑activated receptor γ in brain microvascular endothelium cells during cerebral ischemia Mingjing Xu, Xianli Yang, Qing Zeng, He He, Pengcheng Lu, Guozhi Huang View Abstract ❯
[Corrigendum] Neurotoxin β‑N‑methylamino‑L‑alanine induces endoplasmic reticulum stress‑mediated neuronal apoptosis Haiying Shen, Kiyoon Kim, Yoojung Oh, Kyung Sik Yoon, Hyung Hwan Baik, Sung Soo Kim, Joohun Ha, Insug Kang, Wonchae Choe View Abstract ❯

20-22 September, 2018, Metropolitan Hotel, Athens, Greece 23nd World Congress on Advances in Oncology & 22th International Symposium on Molecular Medicine 18-19 September 2018, Pre-Congress Workshop: 'MicroRNA Analysis'

28-30 March, 2019, Tawana Hotel, Bangkok, Thailand 23 rd International Symposium on Molecular Medicine

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Opioid Use After Open Resection or VATS for Early-Stage Lung Cancer

This population-based study compares opioid use in patients with non–small cell lung cancer who underwent open resection vs video-assisted thoracoscopic surgery.

https://ift.tt/2QU6pMQ

Phase 1-2a Study of EBNA1 Inhibitor, VK-2019, in Patients With Epstein-Barr Virus-positive Nasopharyngeal Cancer

Conditions:   Nasopharyngeal Carcinoma;   Nasopharyngeal Cancer
Intervention:   Drug: VK-2019
Sponsors:   Troy Messick;   Stanford University;   National Cancer Institute (NCI)
Not yet recruiting

https://ift.tt/2xM299D

Diagnostic Accuracy of Salivary DNA Integrity Index in Oral Malignant and Premalignant Lesions

Conditions:   Oral Cancer;   Oral Lichen Planus;   Oral Leukoplakia
Intervention:   Diagnostic Test: DNA Integrity Index
Sponsor:   Cairo University
Not yet recruiting

https://ift.tt/2QUM3De

Interventions for Patients With Alzheimer's Disease and Dysphagia

Conditions:   Dementia;   Dysphagia
Interventions:   Device: Isometric tongue strengthening;   Drug: Biotene
Sponsor:   University of Wisconsin, Madison
Recruiting

https://ift.tt/2xKeknm

Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery: A Randomized Controlled Trial

Conditions:   Cancer of Head and Neck;   Narcotic Use
Interventions:   Drug: Gabapentin;   Drug: Placebo - Concentrate
Sponsor:   University of California, Davis
Not yet recruiting

https://ift.tt/2QULQ2U

Effects of topical applications of porcine acellular urinary bladder matrix and Centella asiatica extract on oral wound healing in a rat model

Abstract

Objectives

To evaluate the effects of topical applications of porcine acellular urinary bladder matrix (AUBM) and Centella asiatica extract (CAE) on the healing of tongue wounds in a rat model.

Materials and methods

Wounds were made in the tongue using a punch tool in 64 male Sprague-Dawley rats, randomized into four groups (n = 16 per group): group 1 (control), group 2 (CAE), group 3 (AUBM mixed with orabase), and group 4 (orabase). No product was applied in group 1 and groups 2–4 received three daily topical applications. The animals were weighed on day 0 and at the time of euthanasia. Four rats in each group were euthanized at days 2, 7, 14, and 21 and the tongues were processed for: macroscopic morphometric analysis, myeloperoxidase (MPO) and malondialdehyde (MDA) levels, histological wound repair (degree of reepithelialization and inflammation), and CD31 positivity.

Results

The animals' weight gain, histological wound repair, and CD31 positivity from greatest to least were: AUBM > CAE > orabase > control. Percentage of tongue occupied by wound, MPO, and MPA levels from least to greatest were: AUBM < CAE < orabase < control, whereby the AUBM group showed significant differences (p ≤ 0.05) in comparison with the other groups on days 2, 7, 14, and 21 for percentage of tongue occupied by wound and MDA and on days 7, 14, and 21 for MPO.

Conclusions

CAE is effective for oral tissue regeneration, while AUBM is an even more potent means of oral mucosa regeneration.

Clinical relevance

AUBM may be beneficial to patients with oral wounds; this finding requires further clinical and laboratory investigation.

https://ift.tt/2IaSVs3

Case series of oral minoxidil for androgenetic and traction alopecia: Tolerability & the five C's of oral therapy

Dermatologic Therapy, EarlyView.


https://ift.tt/2IbDHTU

Helicobacter pylori‐associated peptic ulcer disease: A retrospective analysis of post‐treatment testing practices

Helicobacter, EarlyView.


https://ift.tt/2xCTqqR

Helicobacter pylori and non‐alcoholic fatty liver disease: A new enigma?

Helicobacter, EarlyView.


https://ift.tt/2MXbcKc

Scholar : New articles have been published for Journal of Natural History, Volume 52, Issue 31-32

The online platform for Taylor & Francis Online content The following articles have been newly published in the issue Journal of Natural History, Volume 52, Issue 31-32 on Taylor & Francis Online: Articles Seven new species of the genus Pseudostegana (Diptera: Drosophilidae) from South-west China, with DNA barcoding information Lu Gong, Hongwei Chen Pages: 2097-2119 | DOI: 10.1080/00222933.2018.1515381 The issue is in progress. To view all articles already published in this issue, please visit: https://www.tandfonline.com/toc/tnah20/52/31-32 Hoping to have your article read by anyone, anywhere and at any time? Find out more about publishing open access with Ecosystem Health and Sustainability. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Expression of Transcripts Selective for GABA Neuron Subpopulations across the Cortical Visuospatial Working Memory Network in the Healthy State and Schizophrenia

Abstract

Visuospatial working memory (WM), which is impaired in schizophrenia, depends on a distributed network including visual, posterior parietal, and dorsolateral prefrontal cortical regions. Within each region, information processing is differentially regulated by subsets of γ-aminobutyric acid (GABA) neurons that express parvalbumin (PV), somatostatin (SST), or vasoactive intestinal peptide (VIP). In schizophrenia, WM impairments have been associated with alterations of PV and SST neurons in the dorsolateral prefrontal cortex. Here, we quantified transcripts selectively expressed in GABA neuron subsets across four cortical regions in the WM network from comparison and schizophrenia subjects. In comparison subjects, PV mRNA levels declined and SST mRNA levels increased from posterior to anterior regions, whereas VIP mRNA levels were comparable across regions except for the primary visual cortex (V1). In schizophrenia subjects, each transcript in PV and SST neurons exhibited similar alterations across all regions, whereas transcripts in VIP neurons were unaltered in any region except for V1. These findings suggest that the contribution of each GABA neuron subset to inhibitory regulation of local circuitry normally differs across cortical regions of the visuospatial WM network and that in schizophrenia alterations of PV and SST neurons are a shared feature across these regions, whereas VIP neurons are affected only in V1.

https://ift.tt/2Q0E1av

Role of serum 25‐hydroxyvitamin D levels and vitamin D receptor gene polymorphisms in patients with rosacea: a case–control study

Clinical and Experimental Dermatology, EarlyView.


https://ift.tt/2NzIRyQ

Topical dapsone gel is a new treatment option for acne agminata

Clinical and Experimental Dermatology, EarlyView.


https://ift.tt/2DrWICD

Measurement properties of three assessments of burden used in atopic dermatitis in adults

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2OSWV2Q

Differential Diagnosis in Dermatology, 2nd edn. Klaus F. Helm, Galen T. Foulke and James G. Marks Jr. London: JP Medical Ltd, 2017; 312 pp. ISBN: 978‐1909836198. Price £110·00.

British Journal of Dermatology, EarlyView.


https://ift.tt/2zpebHZ

Persistence of treatment with biologics for patients with psoriasis: a real‐world analysis of 16 545 biologic‐naïve patients from the French National Health Insurance database (SNIIRAM)

British Journal of Dermatology, EarlyView.


https://ift.tt/2OJokEr

Handbook of Dermatology Treatments. Michael Ardern‐Jones, Philip Hampton and Ruth Ann Vleugels (eds). London: JP Medical Ltd, 2017; 176pp. ISBN: 978‐1909836211. Price £65·00.

British Journal of Dermatology, EarlyView.


https://ift.tt/2zpIwpQ

Estradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in rats

Journal of Neuroendocrinology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2MWcHZ7

Efficacy and safety of 3D-conformal half body irradiation in patients with multiple bone metastases

Abstract

Half-body irradiation (HBI) represented a standard treatment for multiple painful bone metastases (BMs). However, its use has progressively reduced due to the associated toxicity rates. The aim of this paper was to evaluate HBI delivered by conformal radiotherapy (RT) technique in a large patients population with widespread BMs. HBI was delivered in 3 Gy fractions, bid, ≥ 6 h apart, on 2 consecutive days (total dose: 12 Gy) using 3-dimensional conformal RT (3D-CRT) box technique. The target included pelvic bones, lumbar-sacral vertebrae and upper third of femurs. Acute and late toxicity was scored based on RTOG and EORTC–RTOG scales, respectively. Pain was evaluated using the Pain-Drug scores and the Visual Analog Scale (VAS). One hundred and eighty patients were eligible for inclusion in this retrospective analysis. Grade 3 and 4 acute toxicity rates were 1.1% and 0.0%, respectively. Mean VAS before and after HBI was 5.3 versus 2.7, respectively (p: 0.0001). Based on VAS, 37.5% of patients showed complete pain relief (VAS: 0) while 38.1% had partial response (≥ 2-point VAS reduction). Overall, Pain and Drug Score reduction was observed in 76.3% and 50.4% of patients, respectively. 1-, 2-, and 3-year pain progression free survival was 77.0%, 63.4%, and 52.7%, respectively. Thirty patients (16.7%) underwent RT retreatment on the same site with median 15.9 months interval (range 2–126 months). HBI delivered with 3D-CRT technique is safe and effective. It provides long lasting pain control in patients with multiple BMs with negligible rates of relevant toxicity.

https://ift.tt/2zphi2w

Primary Cutaneous Non‐Pigmented Mycotic Cyst Contained in an Epidermal Inclusion Cyst: Case Report and Review of the Literature

Journal of Cutaneous Pathology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2I8fbTl

Role of Helicobacter pylori infection in cancer‐associated fibroblast‐induced epithelial‐mesenchymal transition in vitro

Helicobacter, EarlyView.


https://ift.tt/2QT6gcz

Subcutaneous nodules at progesterone injection sites after fertility treatment

Australasian Journal of Dermatology, EarlyView.


https://ift.tt/2OGKE1n

IgG/IgA pemphigus: Report of a rare subtype of pemphigus

Australasian Journal of Dermatology, EarlyView.


https://ift.tt/2zqfwOQ

Clinical and dermoscopic features of pleomorphic dermal sarcoma

Australasian Journal of Dermatology, EarlyView.


https://ift.tt/2OGKAPb

Use of a lumbar puncture needle to reduce the number of needle insertions in infiltration local anaesthesia of large areas in dermatologic surgery

Australasian Journal of Dermatology, EarlyView.


https://ift.tt/2zpKaaR

Tanning, selfies and social media

Australasian Journal of Dermatology, EarlyView.


https://ift.tt/2OGKvLn

Facial trauma reconstruction with polymethyl methacrylate—A case report

Journal of Cosmetic Dermatology, EarlyView.


https://ift.tt/2QTIvkz

Assessment of practice efficacy by retrospective analysis of long‐term patient outcomes: A proposed method

Journal of Cosmetic Dermatology, EarlyView.


https://ift.tt/2xGk0i2

Appearance‐based vs health‐based sun protective messages: A randomized, double‐blind controlled study

Journal of Cosmetic Dermatology, EarlyView.


https://ift.tt/2QNzJER

Effects of contrast cryolipolysis on flank region adiposity: Case study

Journal of Cosmetic Dermatology, EarlyView.


https://ift.tt/2xI0vFT

Three‐dimensional nail imaging by optical coherence tomography: a novel biomarker of response to therapy for nail disease in psoriasis and psoriatic arthritis

Clinical and Experimental Dermatology, EarlyView.


https://ift.tt/2MZLYet

The meshed biological matrix in immediate, definitive breast reconstruction

The aim of this study is to verify the advantages of using a meshed biological matrix (U.I.B.M.-Italian Patent N° 283625) compared to the intact one. A prospective double blind randomized clinical trial with 46 cases of immediate breast reconstruction was performed. The utilization of a meshed biological matrix results in less drainage, reduced need for drains after a few days and a very small percentage rate of seromas and complications, if compared with the utilization of an intact biological matrix.

https://ift.tt/2PZt9K9

An Alternative Approach to the Intraoperative Indocyanine Green Angiography (ICGA) in reconstructive surgery

Indocyanine Green (ICG) is a nontoxic, near- infrared fluorescent dye that has been used for imaging since the 1950s to evaluate liver perfusion and in cardiology.1 It has more recently gained traction in other key areas of reconstructive surgery such as sentinel node biopsy in breast and melanoma skin cancers, lymphangiography in the surgical management of lymphedema and in assessing flap viability in free tissue transfers.1,2

https://ift.tt/2NXgcDp

Local Recurrence and Quality of Life After Adjuvant Radiation Therapy in High‐Risk Squamous Cell Carcinoma

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2zoU6Bo

Subacute cutaneous lupus erythematosus and dermatomyositis associated with anti‐programmed cell death (PD)‐1 therapy

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2OKfI0r

Molecular cloning and characterization of an isotocin paralog ([V8] isotocin) in catfishes (superorder Ostariophysi): origin traced likely to the fish‐specific whole genome duplication

Journal of Neuroendocrinology, Volume 0, Issue ja, -Not available-.


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Issue Information

Helicobacter, Volume 23, Issue 5, October 2018.


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Scholar : Addiction Research & Theory, Volume 26, Issue 6, December 2018 is now available online on Taylor & Francis Online

The online platform for Taylor & Francis Online content Addiction Research & Theory, Volume 26, Issue 6, December 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: Original Article Oniomaniacs: the popular framing of consumption as a disease Johan Edman & Josefine Berndt Pages: 431-438 | DOI: 10.1080/16066359.2017.1396585 The pitfalls of prevalence estimation: the case of regular and dependent methamphetamine use in Australia Paul M. Dietze, Brendan Quinn, Nick Scott, Rebecca Jenkinson, Jenny Chalmers & John L. Fitzgerald Pages: 439-446 | DOI: 10.1080/16066359.2017.1388373 Family functioning and gambling problems in young adulthood: the role of the concordance of values Pawel Sleczka, Barbara Braun, Bettina Grüne, Gerhard Bühringer & Ludwig Kraus Pages: 447-456 | DOI: 10.1080/16066359.2017.1393531 "Everything is telling you to drink": understanding the functional significance of alcogenic environments for young adult drinkers Kimberley M. Hill, David R. Foxcroft & Michael Pilling Pages: 457-464 | DOI: 10.1080/16066359.2017.1395022 Opinion Piece Supply control, demand reduction or harm reduction? Developments and directions for drug policy in Nigeria Ediomo-Ubong E. Nelson & Richard Pates Pages: 465-469 | DOI: 10.1080/16066359.2017.1406480 Original Article The feasibility of alcohol screening and interventions in emergency care: a comparison of primary and specialised health care settings Katariina Warpenius, Marja Johanna Holmila & Anne Heikkilä Pages: 470-477 | DOI: 10.1080/16066359.2017.1406481 Facebook addiction and impulsive decision-making Daniel Delaney, L. A. R. Stein & Russell Gruber Pages: 478-486 | DOI: 10.1080/16066359.2017.1406482 Low-risk drinking guidelines to reduce alcohol-related harm: Delphi survey to explore aspects 'beyond epidemiology' Pia Mäkelä & Marjatta Montonen Pages: 487-497 | DOI: 10.1080/16066359.2018.1434155 Predicting cannabis use among adolescents in four European Countries: combining personal values and the theory of planned behaviour Ramon Morell-Gomis, Daniel Lloret Irles, Juan Antonio Moriano, Sergio Edú-Valsania & Ana Laguía González Pages: 498-506 | DOI: 10.1080/16066359.2018.1443214 Missed opportunities: a qualitative study of views and experiences of smoking cessation amongst adults in substance misuse treatment Hannah Walsh, Maria Duaso & Ann McNeill Pages: 507-513 | DOI: 10.1080/16066359.2018.1441403 Configurations of gambling change and harm: qualitative findings from the Swedish longitudinal gambling study (Swelogs) | Eva Samuelsson, Kristina Sundqvist & Per Binde Pages: 514-524 | DOI: 10.1080/16066359.2018.1448390 Skill sets for family members and friends to help motivate a smoker to seek treatment: research to practice Tabetha A. Brockman, Christi A. Patten & Amy Lukowski Pages: 525-532 | DOI: 10.1080/16066359.2018.1450872 'All suffering together': student drinkers' experiences of alcohol hangover Christine Griffin, Madeleine Freeman, Sally Adams & Paula Smith Pages: 533-540 | DOI: 10.1080/16066359.2018.1453063 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

A scoping review of caries risk management protocols in Australia and New Zealand

Australian Dental Journal, Volume 0, Issue ja, -Not available-.


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