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Πέμπτη 25 Οκτωβρίου 2018

Scholar : CPAP - νέα αποτελέσματα

The infant with severe bronchiolitis: from HFNC to CPAP and mechanical ventilation.

A Wolfler, G Raimondi, C de Paganis Pagan, E Zoia - Minerva pediatrica, 2018
INTRODUCTION: Bronchiolitis is one of the most frequent reasons for PICU
admission in children less than 1 year of age. It causes a wide spectrum of clinical
scenarios from mild to severe respiratory failure and supportive therapy range from …
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[PDF] Breathing assist device

CP Hart - US Patent App. 16/003,558, 2018
… of OSA can include lifestyle changes, the use of mechanical devices, such as oral or nasal
devices that augment the airway, surgical procedures to enlarge and stabilize the airway
during sleep, and continuous or variable positive airway pressure (CPAP, VPAP) devices …
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FAILING ASTHMATIC

C COMPLAINT - Acute Care Casebook, 2018
… A trial of nonin- vasive positive pressure ventilation is begun using continuous positive
airway pressure (CPAP) while he sits upright on the stretcher … on an infusion of Albuterol
2 g magnesium is now continuously administered inline with the CPAP device …
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Ventricular arrhythmias in patients with obstructive sleep apnea.

R Marinheiro, L Parreira, P Amador, D Mesquita… - Current cardiology reviews, 2018
… Treatment of OSA with continuous positive airway pressure (CPAP) has the
potential to reduce arrhythmias and confer a mortality benefit. Read Article
at publisher's site. How does Europe PMC derive its citations network? • Web …
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Implication of mixed sleep apnea events in adult patients with obstructive sleep apnea-hypopnea syndrome

X Yang, Y Xiao, B Han, K Lin, X Niu, X Chen - Sleep and Breathing, 2018
… and OSAHS. Yamauchi et al. found that patients with MSA events had significantly
poorer compliance with continuous positive airway pressure (CPAP) as compared
with pure OSAHS patients [7]. Similarly, Xie et al. reported a …
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[PDF] Non-invasive mechanical ventilation in COPD

A Fayed - J Pulm Med Resp Dis, 2018
… NIMV is a mechanical respiratory support delivered via an in- terface (eg,
nasal prongs or mask, face mask, or helmet) without the endotracheal
intubation to give a continuous positive airway pressure (CPAP) or bilevel …
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Society Guidelines

U TIRODKER - The Pediatric Procedural Sedation Handbook, 2018
… Advanced Life Support (PALS) who monitors the patient but also may assist
in interruptible tasks PALS trained and able to rescue the patient from known
sedation complications, including bag-valve-mask (BVM) and continuous …
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[PDF] Connectors for connecting components of a breathing apparatus

RF Flower, CY Lau, PR Kwok, CJ Baxter, AM Ozolins… - US Patent App. 16/004,551, 2018
… conduit delivers pressurized gas from the flow generator to the patient
interface in communication with the patient's upper airways for treatment,
eg, of Sleep Disordered Breathing (SDB) with Positive Airway Pressure …
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[PDF] Indian Journal of Nursing Sciences

MS D'Souza, S Balachandran - 2018
… Right hemicolectomy and exploratory laparotomy for small bowel infarction were done.
She is unconscious with sedation and is mechanically ventilated. She is on CPAP/PS
mode of ventilation support through tracheotomy tube No. 8.0 mms …
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[HTML] Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth

A Hamvas, R Feng, Y Bi, F Wang, S Bhattacharya… - BMC Genetics, 2018
… This respiratory support included invasive (mechanical ventilation) and non- invasive
(CPAP, high flow nasal cannula > 2 l/min flow) approaches, with or without supplemental
oxygen (ie some infants required respiratory support but with FiO2 0.21) …
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Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.



Scholar : ΜΕΝΙΕΡΕ - νέα αποτελέσματα

[PDF] Hyperacusis and its Management

AA Danesh - 2018
… Tyler, 2015 Page 7. Other Underlying factors include: • Bell's Palsy •
Temporomandibular joint problems • Central Nervous System damage •
Meniere's Disease • Hypothyroidism • Lyme Disease • PTSD • Depression • …
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Hearing function after betahistine therapy in patients with Mé niأ¨ re's disease.

SJ Seyed Tootoonchi, S Ghiasi, P Shadara… - Brazilian journal of …, 2018
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VERTIGO—POSTERIOR STROKE

C COMPLAINT - Acute Care Casebook, 2018
… DIFFERENTIAL DIAGNOSES Posterior stroke or hemorrhage Brainstem mass or tumor
Vestibular neuritis Substance use/medication side effects Benign paroxysmal positional
vertigo/Meniere's disease 1. 2. 3. 4. 5. TESTS AND IMAGING Complete blood count: normal …
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PENETRATING CHEST TRAUMA

C COMPLAINT - Acute Care Casebook, 2018
Page 381. CHAPTER 7 3 PENETRATING CHEST TRAUMA KATHERINE BIGGS*
SETTING Military Aid Station in a Combat Zone, Surgical Capability CHIEF
COMPLAINT Hit by a Rocket-Propelled Grenade (RPG) HISTORY …
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[PDF] HUMAZNIZED AFFINITY MATURED ANIT-FcRn ANTIBODIES

LJ Blumberg, RS Blumberg, SD Jones, D Roopenian… - US Patent App. 15/811,218, 2018
US20180291101A1 - HUMAZNIZED AFFINITY MATURED ANIT-FcRn ANTIBODIES -
Google Patents. HUMAZNIZED AFFINITY MATURED ANIT-FcRn ANTIBODIES.
Download PDF Info. Publication number US20180291101A1 …
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[PDF] Single Chain Fc Fusion Proteins

J Alvarez, DT Moustakas, HR Brodkin, LA Mcsweeney - US Patent App. 15/949,596, 2018
US20180289825A1 - Single Chain Fc Fusion Proteins - Google Patents. Single Chain
Fc Fusion Proteins. Download PDF Info. Publication number US20180289825A1.
US20180289825A1 US15949596 US201815949596A US2018289825A1 …
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Compositions and methods for the depletion of cd137+ cells

A HARTIGAN, A Boitano, M Cooke, MD Hoban… - US Patent App. 15/875,793, 2018
US20180289832A1 - Compositions and methods for the depletion of cd137+ cells - Google
Patents. Compositions and methods for the depletion of cd137+ cells. Download PDF Info.
Publication number US20180289832A1. US20180289832A1 …
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Compounds and methods for promoting stress resistance

C Kenyon, P Zhang, J Cregg, KH Ang, M Arkin - US Patent App. 15/766,797, 2018
US20180289682A1 - Compounds and methods for promoting stress resistance - Google
Patents. Compounds and methods for promoting stress resistance. Download PDF Info.
Publication number US20180289682A1. US20180289682A1 …
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Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.



Scholar : ΑΠΟΚΑΤΑΣΤΑΣΗ - νέα αποτελέσμ

[PDF] Δυνατότητες ανάπτυξης-αγροτορισμού στην ορεινή Ναυπακτία

ΗΑΜ Μουλάς, ΓΑΜ Μαράτος - 2018
… Χάνι Μπανιά Βλαχοµάνδρας 32.426,07 € ∆ΗΜΟΣ ΠΥΛΗΝΗΣ Αποκατάσταση
υδρόµυλου ∆.∆. Φαµήλας του ∆ήµου Πυλήνης Φαµήλα 56.286,27 € …
Καταφυγίου 468.600,00 € ΚΑΛΟΓΕΡΗΣ ΑΝ∆ΡΕΑΣ Αποκατάσταση εξωτερικών …
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Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.



Scholar : ΓΛΩΣΣΙΤΙΣ - νέα αποτελέσματα

Technical Annexes

DA Bradt, CM Drummond - Reference Manual for Humanitarian Health …, 2019
Page 1. 151 © David A. Bradt 2019 DA Bradt, CM Drummond, Reference Manual
for Humanitarian Health Professionals, https://ift.tt/2JlDK01
Technical Annexes Guidance Notes These annexes contain …
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Scholar : Laryngomalacia - νέα αποτελέσματα

Standards for pediatric FAE and sedation have been published separately, although standards for sedation specific to FAE in children have not.

P Assessment - The Pediatric Procedural Sedation Handbook, 2018
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The Premature Infant

JE HAVIDICH, RH EVANS - The Pediatric Procedural Sedation Handbook, 2018
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Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.



The different roles of 5-HT1A/2A receptors in fluoxetine ameliorated pigmentation of C57BL/6 mouse skin in response to stress

Publication date: Available online 25 October 2018

Source: Journal of Dermatological Science

Author(s): Liangliang Zhou, Minxuan Cai, Yingying Ren, Huali Wu, Meng Liu, Haijuan Chen, Jing Shang

Abstract
Background

5-HT1 A receptor was participated in fluoxetine induced melanogenesis in melanocytes and in normal C57BL/6 mice, but we know little about whether other 5-HT receptors are involved in regulation of fluoxetine promotes pigmentation.

Objective

To investigate the role of 5-HT receptors in regulation of fluoxetine ameliorates chronic unpredictable mild stress (CUMS) and chronic restraint stress (CRS) induce hypopigmentation in C57BL/6 mice.

Methods

CUMS and CRS were used to induce depigmentation in mice and evaluate the effect of fluoxetine. Western blot, immunohistochemistry and Q-PCR assay were used to determine the levels of protein and mRNA. Masson Fontana staining was used for melanin staining and FITC-Phalloidin staining was used to detect the expression of F-actin. Zebrafish and B16F10 cells were used for the mechanism research.

Results

Fluoxetine (2.6 mg/kg, ig) ameliorated hypopigmentation induced by CUMS and CRS in mice, significantly increased the mRNA and protein levels of 5-HT1 A and 5-HT2 A receptors in mice and B16F10 cells. The effect of fluoxetine on melanogenesis in B16F10 cells and zebrafish were inhibited by WAY100635 (a selective 5-HT1 A receptor antagonist) and ketanserin (a 5-HT2 A receptor antagonist), respectively. Activation of p38 MAPK signaling pathways was contributed to fluoxetine induced melanogenesis and inhibited by WAY100635, but not ketanserin. However, ketanserin selectively weakened the action of fluoxetine promoted migration and up-regulated Rab27a protein expression in B16F10 cells.

Conclusions

5-HT1 A and 2 A receptors contribute to melanogenesis and migration property of fluoxetine. The newly revealed mechanism indicates that fluoxetine and its analogues may be a potential drug for treatment of depigmentation disorders.

Graphical Abstract

Graphical abstract for this article

Stress, specifically chronic unpredictable stress and chronic restrained stress, induce depigmentation in C57BL/6 mice. Fluoxetine promoted melanin production and the migration of melanocytes via 5-HT1 A receptor and 5-HT2 A receptor, respectively.



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