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Τρίτη 20 Νοεμβρίου 2018

Scholar : Obstructive sleep apnea - νέα αποτελέσματα

The relationship between obstructive sleep apnea and insomnia: A population-based cross-sectional polysomnographic study

BL Uhlig, K Hagen, M Engstrøm, M Stjern, GB Gravdahl… - Sleep Medicine, 2018
Background The relationship between insomnia and objectively measured
obstructive sleep apnea (OSA) severity has not previously been investigated in both
genders in the general population. The main aim of this population-based …
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Successful upper airway stimulation therapy in an adult Down syndrome patient with severe obstructive sleep apnea

E Van de Perck, J Beyers, M Dieltjens, SO de Beeck… - Sleep and Breathing, 2018
Purpose The aim of this study was to report on the successful application of upper
airway stimulation (UAS) therapy in an adult Down syndrome (DS) patient with
severe obstructive sleep apnea (OSA) and continuous positive airway pressure …
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[HTML] Inherent vs. Induced Loop Gain Abnormalities in Obstructive Sleep Apnea

N Deacon-Diaz, A Malhotra - Frontiers in Neurology, 2018
Unstable ventilatory chemoreflex control, quantified as loop gain, is recognized as
one of four key pathophysiological traits that contribute to cause obstructive sleep
apnea (OSA). Novel treatments aimed at reducing loop gain are being investigated …
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The Prediction of Obstructive Sleep Apnea Using Data Mining Approaches.

Z Manoochehri, M Rezaei, N Salari, H Khazaie… - Archives of Iranian medicine, 2018
BACKGROUND: Obstructive sleep apnea (OSA) which is the most common sleep
disorder breathing (SDB), imposes heavy costs on health and economy. The aim of
this study was to provide models based on data mining approaches (C5. 0 decision …
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Long‐term swallowing performance following transoral robotic surgery for obstructive sleep apnea

M Paker, I Duek, F Awwad, L Benyamini, T Meshyeev… - The Laryngoscope, 2018
Objectives/Hypothesis This study aimed to evaluate the long‐term swallowing
performance following transoral robotic surgery (TORS) to the base of tongue (BOT)
in the treatment of obstructive sleep apnea (OSA). Study Design Retrospective and …
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Current perspectives on the correlation of nocturnal enuresis with obstructive sleep apnea in children

MS Su, L Xu, WF Pan, CC Li - World Journal of Pediatrics, 2018
Background Obstructive sleep apnea (OSA) and nocturnal enuresis (NE) are
common clinical problems in children. OSA and NE are thought to be interrelated, but
the exact pathophysiological mechanisms are not yet clear. This review aims to …
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Recommended Reading from the University of Toronto Sleep Medicine Fellows

E Perger, C Gonzaga-Carvalho, T Inami, CM Ryan… - American journal of …, 2018
… Apnea. N Eng J Med (1) Reviewed by Elisa Perger Obstructive sleep apnea (OSA) is
associated with increased cardiovascular risk, mediated … or non-sleepy (Epworth Sleepiness
Scale less or equal to 15) (1). Patients were excluded if they had …
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[PDF] Association of Severity of Obstructive sleep apnea syndrome with Body mass index and Neck circumference

RD Waghmare, NS Nair, RM Lokhande, SH Meshram - PARIPEX-INDIAN JOURNAL …, 2018
Introduction: Many patients with OSA are obese. Obesity is believed to predispose to
OSA becausemass loading of the upper airway by adipose tissue in the neck. We in
this study examined the relationship between indices of general obesity like BMI & …
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Dental Sleep Medicine, An Issue of Sleep Medicine Clinics E-Book

J Spencer - 2018
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Obstructive sleep apnea syndrome in children.

C Perez - General dentistry, 2018
Obstructive sleep apnea syndrome (OSAS) in children is defined as a" disorder of
breathing during sleep characterized by prolonged partial upper airway obstruction
[hypopnea] and/or intermittent complete obstruction (obstructive apnea) that disrupts …
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Scholar : Myringotomy and tubes - νέα αποτελέσματα

[HTML] Simulation Platform for Myringotomy with Ventilation Tube Insertion in Adult Ears

AL Chan, RJD Carrillo, KC Ong - Philippine Journal of Otolaryngology-Head and …, 2018
Objective: To develop a ventilation tube insertion simulator for training and
evaluation of otorhinolaryngology residents in myringotomy with ventilating tube
insertion. Methods: Design: Cross-Sectional Study Setting: Tertiary National …
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Infections of the Ear

J Szmuilowicz, R Young - Emergency Medicine Clinics, 2019
… Inflammation obstructs flow through the eustachian tube and creates
conditions favorable for middle ear infections … 5 x5Ruohola, A., Meurman,
O., Nikkari, S. et al. Microbiology of acute otitis media in children with …
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Cochlear Implants in Children: Current Guidelines and Expanding Criteria

RJ Yawn, JB Hunter, DS Haynes - Surgical and Medical Management of Diseases of …, 2019
… Patients with recurrent acute otitis media should have myringotomy tubes
placed when appropriate, as tubes have not been associated with adverse
out- comes in cochlear implant patients … The management of myringotomy …
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Establishing Hearing Implant Programs in Low Resource Settings: Practical and Economic Considerations

SD Emmett, D Pinder, DG Bervinchak, S Juman… - Surgical and Medical …, 2019
Page 276. 21 Establishing Hearing Implant Programs in Low Resource Settings:
Practical and Economic Considerations Susan D. Emmett, Deborah Pinder, Deborah
G. Bervinchak, Solaiman Juman, and Howard W. Francis …
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Incidence of perianaesthetic complications experienced during feline bronchoscopy: a retrospective study

PK Tucker, P MacFarlane - Journal of Feline Medicine and Surgery, 2018
Objectives The aim of this study was to report the incidence of anaesthetic complications
associated with feline bronchoscopy. Methods This was a retrospective ...
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[PDF] Myringitis: an update

K Devaraja - Journal of Otology, 2018
… Levi et al, 2013; Kim, 2011). A history of the previous myringotomy and myringoplasty
has … otitis media, it was found out that the BM was not seen in ears with patent
tympanostomy tubes (Kotikoski et al, 2003b) … dysfunctional Eustachian tube in cold climates …
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[HTML] Anesthesiological risks in mucopolysaccharidoses

A Moretto, MG Bosatra, L Marchesini, S Tesoro - Italian Journal of Pediatrics, 2018
… Myringotomies and related procedures. • Adenotonsillectomy. • Tracheostomy … Abdominal
interventions and feeding tubes. • Tendon release, carpal tunnel, spinal decompression,
hip, knee, foot and other orthopedic surgery. • Ventriculoperitoneal shunt …
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Scholar : ΡΟΧΑΛΗΤΟ - νέα αποτελέσματα

[PDF] Η σχέση μεταξύ των τροφίμων της μεσογειακής διατροφής και του ύπνου.

L Sotiropoulou, Λ Σωτηροπούλου - 2018
Page 1. Τεχνολογικό Εκπαιδευτικό Ίδρυμα Κρήτης Σχολή Τεχνολογίας
Γεωπονίας και Τεχνολογίας Τροφίμων Τμήμα Διατροφής και Διαιτολογίας
Η ΣΧΕΣΗ ΜΕΤΑΞΥ ΤΩΝ ΤΡΟΦΙΜΩΝ ΤΗΣ ΜΕΣΟΓΕΙΑΚΗΣ ΔΙΑΤΡΟΦΗΣ …
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Scholar : Cricotracheal resection - νέα αποτελέσματα

[PDF] Can Modified Laryngosternopexy (Laryngoclaviculopexy) Project the Larynx Anteriorly?

RJD Carrillo, JFF Lapeña - Philippine Journal of Otolaryngology-Head and Neck …, 2018
… Laser dilatation was not successful and he subsequently underwent partial cricotracheal
resection maintaining a posterior cricoid shell to allow intussuception of the distal trachea
and suturing directly to the thyroid framework … The resected airway measured 4.5 cm …
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Ent Issues, an Issue of Clinics in Perinatology

SL Goudy - 2018
… However, patients with severe subglottic stenosis are often tracheostomy dependent.
Open surgical techniques to treat severe disease, such as lar- yngotracheal reconstruction
and cricotracheal resection, offer high rates of tracheostomy decannulation …
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Scholar : ΚΑΡΚΙΝΩΜΑ - νέα αποτελέσματα

[HTML] Η νεφρική προσβολή στην ηπατίτιδα C-Renal hepatitis C

Μ Στάγκου, M Stangou - Ελληνική Νεφρολογία-Hellenic Nephrology, 2018
… διαφορική διάγνωση, είναι άλλες λοιμώξεις (ηπατίτιδα Β, λοιμώδης
ενδοκαρδίτιδα, λοίμωξη από μυκόπλασμα), συστηματικά νοσήματα
(συστηματικός ερυθηματώδης λύκος, σκληρόδερμα, σύνδρομο Sjögren …
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Scholar : Εξωτερική ωτίτιδα - νέα αποτελέσματα

[PDF] Η χρήση των λέιζερ στην οφθαλμολογία και στην παιδιατρική

ΣΧ Αποστόλου - 2018
… βραχύινα κύτταρα, τα δικτυωτά κύτταρα και τα γαγγλιακά κύτταρα. Οι νευρώνες
βρίσκονται σε στενή επαφή μεταξύ τους. Τα εξωτερικά τμήματα των
φωτοϋποδοχέων παγιδεύουν το φως. Ο αμφιβληστροειδής μετατρέπει το …
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Scholar : Παραθυρεοειδής - νέα αποτελέ

[HTML] Σύνθεση διαλύματος αιμοκάθαρσης-Composition of dialysis solution

K Μαυροματίδης, E Καλογιαννίδου, Κ Mavromatidis… - Ελληνική Νεφρολογία …, 2018
… Αν και ο έλεγχος του δευτεροπαθή υπερπαραθυρεοειδισμού είναι
αποτελεσματικότερος με ένα διάλυμα υψηλού ασβεστίου (3,5 mEq/L), θα
πρέπει να αποφεύγεται η υπερβολική καταστολή των παραθυρεοειδών, επειδή …
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Disposable otoscope specula cryotherapy for lesions in convoluted or sensitive locations

Publication date: Available online 20 November 2018

Source: Journal of the American Academy of Dermatology

Author(s): Brett C. Neill, Peter Chow, Isadore S. Tarantino, Daniel J. Aires



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Δευτέρα 19 Νοεμβρίου 2018

Arsenic enhances cell death and DNA damage induced by ultraviolet B exposure in mouse epidermal cells through the production of reactive oxygen species

Summary

Background

Ultraviolet (UV)B radiation has long been considered a carcinogen in both epidemiological surveys and experimental studies. However, recent work has suggested that different dosages of UVB exert different influences on cells. There are also co‐carcinogenesis factors such as arsenic that affect the role of UVB.

Aim

To explore the co‐carcinogenesis effect of UVB and arsenic on the mouse epidermal cell line JB6 and the mechanism underlying it.

Methods

Growth of JB6 cells was measured by MTT assay. We carried out a comet assay to determine the DNA damage caused by UVB and arsenic, and tested the expression of DNA repair protein by western blotting. Reactive oxygen species (ROS) were measured using DCF and DHE staining, and changes in antioxidant enzymes were assessed using western blotting.

Results

Viability assays showed that arsenic increased the UVB‐induced death rate. Arsenic enhanced DNA damage caused by UVB both directly by injury to double‐stranded DNA and indirectly by reducing the capability of DNA repair in JB6 cells. All of these effects are the results of increased ROS generation and reduced expression of the antioxidant enzyme superoxide dismutase (SOD)1.

Conclusion

Arsenic was found to enhance UVB‐induced production of ROS and to downregulate SOD1 expression, leading to DNA damage and apoptosis in mouse skin cells. The combination of arsenic and UVB exposure was found to differentially regulate the expression of SOD1 and SOD2.



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