Somatostatin Receptor Scintigraphy in a Patient with Myocarditis

xlomafota13 shared this article with you from Inoreader Somatostatin Receptor Scintigraphy in a Patient with Myocarditis Via Mol Imaging Radionucl Ther Related Articles Somatostatin Receptor Scintigraphy in a Patient with Myocarditis Mol Imaging Radionucl Ther. 2021 02 09;30(1):50-53 Authors: Amini A, Dehdar F, Jafari E, Gholamrezanezhad A, Assadi M Abstract We report a case of myocarditis imaged with technetium-99m octreotide cardiac single-photon emission computed tomography which showed diffuse uptake in the myocardium, indicating inflammatory reaction to myocardial damage. Somatostatin receptor scintigraphy of the heart could be considered in patients with suspected cardiac inflammation. This could facilitate early diagnosis and guide appropriate treatment. PMID: 33586409 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Small-angle Compton Scatter Artifact in Tc-99m-IDA Hepatobiliary Scintigraphy Resulting in the Breast Overlying the Liver in Planar Dynamic Imaging.

xlomafota13 shared this article with you from Inoreader Small-angle Compton Scatter Artifact in Tc-99m-IDA Hepatobiliary Scintigraphy Resulting in the Breast Overlying the Liver in Planar Dynamic Imaging. Via Mol Imaging Radionucl Ther Related Articles Small-angle Compton Scatter Artifact in Tc-99m-IDA Hepatobiliary Scintigraphy Resulting in the Breast Overlying the Liver in Planar Dynamic Imaging. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):54-56 Authors: Qutbi M Abstract Compton scatter photons are generally considered problematic in nuclear medicine imaging. Therefore, efforts are being made to minimize the involvement of these photons by employing some special strategies in daily practice. Basically, photons scattering at a small angle and traveling in the proper direction stand a chance of getting recorded and thereby participate in the image formation. These photons may create artifactual hot spots in the vicinity of a region with high concentration of radioactivity. The present study focuses on the negative impact of such photons during routine imaging in clinical setting, through an artifact detected in technetium-99m-IDA hepatobiliary scintigraphy, with the purpose of highlighting this issue to the nuclear medicine practitioners. PMID: 33586410 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging.

xlomafota13 shared this article with you from Inoreader Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging. Via Mol Imaging Radionucl Ther Related Articles Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):57-59 Authors: Sağer MS, Bilgiç S, Uslu L, Asa S, Sağer G, Sönmezoğlu K Abstract Vasculitis is a multisystem disease characterized by inflammation with infiltration of leukocytes into the blood vessels. Giant cell arteritis (GCA) is the most common form of vasculitis that mostly affects medium- and large-sized arteries. 18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) is increasingly used to diagnose inflammation of large arteries in GCA. Galium-68 prostate-specific membrane antigen (PSMA) PET/CT has a vital role in the assessment of patients with prostate cancer for recurrence and metastasis of the disease. Various benign and non-prostate malignant conditions may give rise to increased PSMA uptake. Herein, we demonstrate that PSMA uptake can be seen in GCA. PMID: 33586411 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Unexpected Detection of Abscessualized Lung Carcinoma on Tc-99m-HMPAO-labeled Leukocytes Scintigraphy Misdiagnosed on Chest Computed Tomography.

xlomafota13 shared this article with you from Inoreader Unexpected Detection of Abscessualized Lung Carcinoma on Tc-99m-HMPAO-labeled Leukocytes Scintigraphy Misdiagnosed on Chest Computed Tomography. Via Mol Imaging Radionucl Ther Related Articles Unexpected Detection of Abscessualized Lung Carcinoma on Tc-99m-HMPAO-labeled Leukocytes Scintigraphy Misdiagnosed on Chest Computed Tomography. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):60-62 Authors: Cosma L, Frantellizzi V, Pontico M, De Vincentis G Abstract Technetium-99m (Tc-99m)-hexamethylpropylene amine oxime (HMPAO)-labeled leukocytes scintigraphy is well established for investigating and diagnosing infections in bone and soft tissue, as well as for the detection of occult infection. A 71-year-old female who was recently diagnosed with bronchopulmonary neuroendocrine tumor of the right lung was referred for an intermittent fever of unknown origin associated with chill at night for the last month. Chest computed tomography (CT) scan showed a thrombotic widespread of the superior vena cava and a solid pathological tissue in the superior segment of the inferior lobe of the right lung with consensual atelectasis. Being a carrier of port-a-cath, an infection of this device was suspected. Therefore, Tc-99m-HMPAO-labeled leukocytes single-photon emission computed tomography (SPECT) was performed, and matching pairs of CT scan and Tc-99m-HMPAO-labeled white blood cell SPECT images were fused. Through this means, it was found that th e area of the radiotracer increased uptake corresponded with the soft tissue density mass detected by CT scan localized at the inferior lobe of the right lung. The hybrid SPECT/CT fused imaging was crucial for diagnosis of the presence of a lung abscess localized in correspondence with the known lung cancer region. PMID: 33586412 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

68Ga PSMA Uptake at Roux-en-Y Eso-jejunostomy Junction Mimicking the Recurrence of Gastric Carcinoma in PET/CT.

xlomafota13 shared this article with you from Inoreader 68Ga PSMA Uptake at Roux-en-Y Eso-jejunostomy Junction Mimicking the Recurrence of Gastric Carcinoma in PET/CT. Via Mol Imaging Radionucl Ther Related Articles 68Ga PSMA Uptake at Roux-en-Y Eso-jejunostomy Junction Mimicking the Recurrence of Gastric Carcinoma in PET/CT. Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):63-66 Authors: Arslan E, Aksoy T, Cin M, Çakır C, Can Trabulus FD, Çermik TF Abstract A 67-year-old male patient had undergone total gastrectomy and Roux-en-Y eso-jejunostomy 3 years ago for the treatment of tubular adenocarcinoma located at the corpus of the stomach. The patient was diagnosed with Gleason score 8 (4+4) metastatic prostate cancer during the follow-up period and received hormone therapy. Owing to his elevated prostate-specific antigen levels (77 ng/mL), his clinician referred him gallium-68 (68Ga) prostate-specific membrane antigen 11 (PSMA) positron emission tomography/computed tomography (PET/CT) for restaging. PET/CT showed multiple 68Ga PSMA receptor-positive skeletal lesions and linear PSMA activity at the eso-jejunostomy junction. He was then referred to undergo 18fluorine-fluorodeoxyglucose (18F-FDG) PET/CT to screen for gastric carcinoma recurrence. PET/CT images demonstrated no 18F-FDG avid lesion. However, endoscopy and biopsy performed with samples from the eso-jejunostomy junction revealed superficial benign squamous epithelial frag ments. PMID: 33586413 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Neutron Therapy for High‐Grade Salivary Carcinomas in the Adjuvant and Primary Treatment Setting

xlomafota13 shared this article with you from Inoreader Neutron Therapy for High‐Grade Salivary Carcinomas in the Adjuvant and Primary Treatment Setting Via The Laryngoscope Objectives/Hypothesis Our primary objective was to compare differences in survival of patients with high‐grade salivary gland carcinomas (SGCs) receiving adjuvant neutron versus photon radiotherapy using a hospital‐based national cohort and restricted mean survival time (RMST) analysis. Our secondary objective was to compare survival of similar patients treated with primary neutron versus photon radiation. Study Design Multicenter, retrospective population‐based study of patients within the National Cancer Database from 2004 to 2014. Methods One thousand eight hundred forty‐four patients were selected on diagnosis of high‐grade parotid and submandibular malignancies. One thousand seven hundred seventy‐seven patients receiving photon and 67 patients receiving neutron therapy were identified who met inclusion criteria. Patients were then categorized as having primary surgery with adjuvant radiation or primary radiation without prior surgery. Bivariate analysis was performed to assess for differences between groups, and RMST analysis was performed at 1‐, 2‐, and 5‐year timepoints with controlling for available covariate data. Results There was no significant difference in RMST for patients receiving neutrons over photons at 1, 2, and 5 years in the adjuvant setting. Among patients undergoing primary radiotherapy, there was a difference in RMST of 2.29 months at 1 year and 5.05 months at 2 years for neutrons over photons, though this benefit was not observed at 5 years post‐therapy. Conclusions For patients with high grade SGCs undergoing adjuvant photon versus neutron radiotherapy, there was no difference in RMST. There was observed to be a significant difference in RMST at 1 and 2 years among patients undergoing primary neutron therapy of up to 5 months. Given the benefit observed with primary neutron therapy, it should be considered in both the primary and adjuvant treatment setting. Level of Evidence 4 Laryngoscope, 131:541–547, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Coverage for Gender‐Affirming Voice Surgery and Therapy for Transgender Individuals

xlomafota13 shared this article with you from Inoreader Coverage for Gender‐Affirming Voice Surgery and Therapy for Transgender Individuals Via The Laryngoscope Objectives/Hypothesis To determine insurance coverage for gender‐affirming surgery and voice therapy for individuals who seek to align their voice with their gender identity, and to analyze differences based on state‐by‐state transgender equality. Study Design Cross‐sectional study. Methods Policies from the top three commercial insurers per state in 2019 were reviewed. Coverage status was determined by web‐based search, telephone interviews, and email inquiries. A state‐by‐state equality score was calculated based on the number of laws and policies relating to the transgender community. Correlation between number of preauthorized procedures and state equality scores was assessed. Results Of the 150 insurance companies reviewed, only four (2.7%) held favorable policies, whereas 113 (75.8%) provided no coverage. Endoscopic surgery, open surgery, individual voice therapy, and group voice therapy interventions were equally excluded (n = 93, 62.4%). Coverage was not correlated with laws driving transgender equality (P = .782). Conclusions Gender‐affirming voice interventions are seldom covered by commercial insurance companies. Despite established medical necessity and years of experience in practice, gender‐affirming interventions for voice have not yet been fully considered by third‐party payors. Further investigation regarding cost‐effectiveness and treatment efficacy is warranted to improve insurance coverage of voice‐related gender‐affirming care. Level of Evidence NA Laryngoscope, 131:E896–E902, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

An Open‐Source Three‐Dimensionally Printed Laryngeal Model for Injection Laryngoplasty Training

xlomafota13 shared this article with you from Inoreader An Open‐Source Three‐Dimensionally Printed Laryngeal Model for Injection Laryngoplasty Training Via The Laryngoscope Objectives/Hypothesis A limited number of three‐dimensionally (3D)‐printed laryngeal simulators have been described in the literature, only one of which is specifically designed for percutaneous injection laryngoplasty (PIL) training and is currently of limited availability. This study describes the development and evaluation of a high‐fidelity, open‐source, low‐cost 3D‐printed simulator for PIL training, improving on existing models. Study Design Simulator design and survey evaluation. Methods Computed tomography scans of the upper airways were processed with 3D Slicer to generate a computer model of the endolarynx. Blender and Fusion 360 were used to refine the mucosal model and develop casts for silicone injection molding. The casted endolaryngeal structures were inserted into a modified version of a publicly available laryngeal cartilage model. The final models were evaluated by 10 expert laryngologists using a customized version of the Michigan Standard Simulation Experience Scale. Internal consistency and interrater reliability of the survey were evaluated using Cronbach's α and intraclass correlation, respectively. Results Expert laryngologists highly rated the model for measures of fidelity, educational value, and overall quality (mean = 4.8, standard deviation = 0.5; 1 = strongly disagree, 5 = strongly agree). All reviewers rated the model as ready for use as is or with slight modifications. The filament needed for one cartilage model costs $0.96, whereas the silicone needed for one soft‐tissue model costs $1.89. Conclusions Using 3D‐printing technology, we successfully created the first open‐source, low‐cost, and anatomically accurate laryngeal model for injection laryngoplasty training. Our simulator is made freely available for download on Wikifactory with step‐by‐step tutorials for 3D printing, silicone molding, assembly, and use. Level of Evidence NA Laryngoscope, 131:E890–E895, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

IVORY Guidelines (Instructional Videos in Otorhinolaryngology by YO‐IFOS): A Consensus on Surgical Videos in Ear, Nose, and Throat

xlomafota13 shared this article with you from Inoreader IVORY Guidelines (Instructional Videos in Otorhinolaryngology by YO‐IFOS): A Consensus on Surgical Videos in Ear, Nose, and Throat Via The Laryngoscope Objectives/Hypothesis Otolaryngology instructional videos available online are often of poor quality. The objective of this article was to establish international consensus recommendations for the production of educational surgical videos in otolaryngology. Study Design DELPHI survey. Methods Twenty‐seven international respondents participated in this study from 12 countries. Consensus was reached after three rounds of questionnaires following the Delphi methodology. The proposals having reached the 80% agreement threshold in the third round were retained. Results The main recommendations are as follows: 1) Ethics: patients must be anonymized and unrecognizable (apart from plastic surgery if necessary). A signed authorization must be obtained if the person is recognizable. 2) Technical aspects: videos should be edited and in high‐definition (HD) quality if possible. Narration or subtitles and didactic illustrations are recommended. 3) Case presentation: name of pathology and procedure must be specified; the case should be presented with relevant workup. 4) Surgery: surgical procedures should be divided into several distinct stages and include tips and pitfalls. Pathology should be shown if relevant. Key points should be detailed at the end of the procedure. 5) Organ‐specific: type of approach and bilateral audiometry should be specified in otology. Coronal plane computed tomography scans should be shown in endonasal surgery. It is recommended to show pre‐ and postoperative videos in voice surgery and preoperative drawings and photos o f scars in plastic surgery, as well as the ventilation method in airway surgery. Conclusions International recommendations have been determined to assist in the creation and standardization of educational surgical videos in otolaryngology and head and neck surgery. Level of Evidence 5 Laryngoscope, 131:E732–E737, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Long‐term Outcomes for Revision Endoscopic Dacryocystorhinostomy—The Effect of the Primary Approach

xlomafota13 shared this article with you from Inoreader Long‐term Outcomes for Revision Endoscopic Dacryocystorhinostomy—The Effect of the Primary Approach Via The Laryngoscope Objectives/Hypothesis Revision endoscopic dacryocystorhinostomy (END‐DCR) is the preferred approach for failed primary surgeries, yet quality data on long‐term outcomes are lacking. This study aimed to evaluate three aspects of revision END‐DCR: 5‐year success rates, patient satisfaction, and the primary surgical approach's possible impact on revision. Methods This retrospective study included all revision END‐DCRs conducted at Kaplan Medical Center between the years 2002 and 2015. For long‐term follow‐up analysis, two subgroups of first and second revision END‐DCRs with a minimum of documented 5‐year follow‐up after surgery were defined. Data were analyzed according to the primary surgical approach. Surgical success was defined by either anatomical (observed patent lacrimal flow) or functional (symptoms cessation) success. Patient satisfaction was measured by a questionnaire. Results After exclusions, a total of 45 eyes from 38 patients who underwent revision END‐DCR surgeries were included in the study. The yearly success rates from immediate to 5 years following the first revision were 93.3%, 75.5%, 71.1%, 68.9%, 68.9%, and 68.9% for the entire cohort, respectively. Immediate and 5‐year success rates following the second revision were 88.8% and 77.8%, respectively. Primary END‐DCR showed favorable 5‐year success rates and patient satisfaction over primary external dacryocystorhinostomy (EXT‐DCR) in both first and second revisions, but this did not reach significance. Conclusions Revision END‐DCR carries an excellent short‐term success rate, which decreases mainly throughout the first 2 years following surgery. Postoperative follow‐up should be maintained within this timeframe. Revision END‐DCR following either primary endoscopic or EXT‐DCR produces comparable surgical outcomes and patient‐reported satisfaction. Level of Evidence 3b Laryngoscope, 131:E682–E688, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Taste Dysfunction in Chronic Rhinosinusitis

xlomafota13 shared this article with you from Inoreader A Systematic Review and Meta‐Analysis of Taste Dysfunction in Chronic Rhinosinusitis Via The Laryngoscope Objectives Patients with chronic rhinosinusitis (CRS) often describe alterations in sense of taste. These complaints have historically been attributed to olfactory dysfunction; however, there is evidence of direct, objective, gustatory disturbances in the setting of CRS that are not thoroughly characterized. This study sought to investigate and summarize gustatory dysfunction experienced by patients with CRS. Methods PubMed, EMBASE, Cochrane Library, Web of Science, and Scopus databases were reviewed following PRISMA guidelines. English language, original studies investigating objective taste in adult patients with CRS were included. A meta‐analysis with inverse variance, random‐effects model was performed. Results Of 2750 studies screened, 11 articles with 471 unique patients were included. Patients with CRS exhibit worse gustatory function compared to healthy controls (standardized mean difference 0.94 [95% CI, 0.44–1.45]). Hypogeusia was identified in 32/95 (33.7%) patients from three studies that used methods with a validated definition of hypogeusia. Older age, male gender, and smoking history were associated with taste dysfunction, while objective gustatory and olfactory dysfunction were not correlated. Subjective taste and quality of life measures were also not associated with objective taste. The impact of sinus surgery on objective taste is unclear. Conclusion Approximately 34% of patients with CRS experience hypogeusia. Neither olfactory function nor subjective taste were associated with objective gustatory function. Given the substantial prevalence of taste dysfunction patients with CRS, there is significant potential for growth in understanding of pathogenesis, impact on quality of life, and potential treatment strategies of taste impairment in the CRS patient population. Level of Evidence 1 Laryngoscope, 131:482–489, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.