Investigating the composition characteristics of dissolved and particulate/colloidal organic matter in effluent-dominated stream using fluorescence spectroscopy combined with multivariable analysis

Abstract

Fluorescence excitation-emission matrix (EEM) spectroscopy combined with principal component analysis (PCA) and parallel factor analysis (PARAFAC) were used to investigate the compositional characteristics of dissolved and particulate/colloidal organic matter and its correlations with nitrogen, phosphorus, and heavy metals in an effluent-dominated stream, Northern China. The results showed that dissolved organic matter (DOM) was comprised of fulvic-like, humic-like, and protein-like components in the water samples, and fulvic-like substances were the main fraction of DOM among them. Particulate/colloidal organic matter (PcOM) consisted of fulvic-like and protein-like matter. Fulvic-like substances existed in the larger molecular form in PcOM, and they comprised a large amount of nitrogen and polar functional groups. On the other hand, protein-like components in PcOM were low in benzene ring and bound to heavy metals. It could be concluded that nitrogen, phosphorus, and heavy metals in effluent had an effect on the compositional characteristics of natural DOM and PcOM, which may deepen our understanding about the environmental behaviors of organic matter in effluent.

http://ift.tt/2DFv1mt

Epidermal melanocytes of segmental vitiligo show altered expression of E-cadherin, but not P-cadherin

Abstract

Vitiligo is the most common pigmentation disorder, with a worldwide prevalence of 1%. The loss of melanocytes from the skin is the main clinical feature of patients with vitiligo, resulting in depigmentation macules. Vitiligo has been classified into two major forms: non-segmental vitiligo (NSV) and segmental vitiligo (SV). NSV lesions are generally bilateral or symmetrically scattered over the entire body. Onset may occur at any age, but most patients develop vitiligo before 40 years of age, and the depigmentation evolves over time.

This article is protected by copyright. All rights reserved.

http://ift.tt/2rilu2e

Reflectance Confocal Microscopy for the Diagnosis of Langerhans Cell Histiocytosis

Abstract

Langerhans cell histiocytosis (LCH) is a rare proliferative disease occurring in young children. The most affected organs are the bones and the skin (1). The diagnosis of LCH relies on histopathology. Reflectance confocal microscopy (RCM) is a non-invasive imaging technique used to diagnose skin cancer (2). We report that in three children RCM examination of cutaneous lesions of LCH showed specific signs correlated to histopathology.

This article is protected by copyright. All rights reserved.

http://ift.tt/2mLouzm

Metabolic syndrome and its components among Korean submariners: a retrospective cross-sectional study

Abstract

Purpose

Metabolic syndrome (MetS) is a cluster of inter-related risk factors for cardiovascular disease and diabetes. Although submariners tend to be exposed to unhealthy environmental factors, such as a confined work environment, physical inactivity, and circadian disruption, little is known regarding whether the risks of MetS and its components are associated with submarine service. The present study aimed to evaluate the risks of MetS and its components among submariners.

Methods

A total of 5090 subjects (513 submariners and 4577 non-submariners) were included in the present study. We calculated the age-standardized and age-specific prevalences of MetS. The associations between submarine service and the risks of MetS and its components were evaluated using logistic regression analysis after adjusting for age, service rank, and lifestyle factors.

Results

The age-standardized prevalences of MetS were 17.6 and 15.1% among submariners and non-submariners, respectively. Compared to non-submariners, submariners had higher risks of MetS (odds ratio [OR] 1.31, 95% confidence interval [CI] 1.02, 1.68), low high-density lipoprotein cholesterol (OR 1.73, 95% CI 1.36, 2.20), and impaired fasting glucose (OR 1.46, 95% CI 1.21, 1.76). When we stratified the subjects according to physical activity, an increased risk of elevated blood pressure associated with submarine service was evident only in the subgroup with moderate or vigorous physical activity (P for interaction = 0.006).

Conclusion

Submariners had higher risks of MetS and some MetS components, compared to non-submariners. These findings suggest that special efforts are needed to prevent and manage MetS among individuals who are expected to be exposed to submarine environment.

http://ift.tt/2Db6Uuy

Anti-cancer Effects of HNHA and Lenvatinib by the Suppression of EMT-Mediated Drug Resistance in Cancer Stem Cells

Publication date: February 2018
Source:Neoplasia, Volume 20, Issue 2
Author(s): Yong Sang Lee, Seok-Mo Kim, Bup-Woo Kim, Ho Jin Chang, Soo Young Kim, Cheong Soo Park, Ki Cheong Park, Hang-Seok Chang
Anaplastic thyroid cancer (ATC) constitutes less than 2% of total thyroid cancers but accounts for 20–40% of thyroid cancer-related deaths. Cancer stem cell drug resistance represents a primary factor hindering treatment. This study aimed to develop targeted agents against thyroid malignancy, focusing on individual and synergistic effects of HNHA (histone deacetylase), lenvatinib (FGFR), and sorafenib (tyrosine kinase) inhibitors. Patients with biochemically and histologically proven papillary thyroid cancer (PTC) and ATC were included. Cell samples were obtained from patients at the Thyroid Cancer Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. PTC and ATC cells were treated with lenvatinib or sorafenib, alone or in combination with HNHA. Tumor-bearing mice (10/group) were administered 10 mg/kg lenvatinib (p.o.) or 40 mg/kg sorafenib (p.o.), alone or in combination with 25 mg/kg HNHA (i.p.) once every three days. Gene expression in patient-derived PTC and ATC cells was compared using a microarray approach. Cellular apoptosis and proliferation were examined by immunohistochemistry and MTT assays. Tumor volume and cell properties were examined in the mouse xenograft model. HNHA-lenvatinib combined treatment induced markers of cell cycle arrest and apoptosis and suppressed anti-apoptosis markers, epithelial-mesenchymal transition (EMT), and the FGFR signaling pathway. Combined treatment induced significant tumor shrinkage in the xenograft model. HNHA-lenvatinib combination treatment thus blocked the FGFR signaling pathway, which is important for EMT. Treatment with HNHA-lenvatinib combination was more effective than either agent alone or sorafenib-HNHA combination. These findings have implications for ATC treatment by preventing drug resistance in cancer stem cells.



http://ift.tt/2FLLcPB

IDH1R132H Promotes Malignant Transformation of Benign Prostatic Epithelium by Dysregulating MicroRNAs: Involvement of IGF1R-AKT/STAT3 Signaling Pathway

Publication date: February 2018
Source:Neoplasia, Volume 20, Issue 2
Author(s): Lili Zhang, Mei Qi, Tingting Feng, Jing Hu, Lin Wang, Xinjun Li, Wei Gao, Hui Liu, Meng Jiao, Zhen Wu, Xinnuo Bai, Yifan Bie, Long Liu, Bo Han
Risk stratification using molecular features could potentially help distinguish indolent from aggressive prostate cancer (PCa). Mutations in isocitrate dehydrogenase (IDH) acquire an abnormal enzymatic activity, resulting in the production of 2-hydroxyglutarate and alterations in cellular metabolism, histone modification, and DNA methylation. Mutant IDH1 has been identified in various human malignancies, and IDH1R132H constituted the vast majority of mutational events of IDH1. Most recent studies suggested that IDH1 mutations define a methylator subtype in PCa. However, the function of IDH1R132H in PCa development and progression is largely unknown. In this study, we showed that the prevalence of IDH1R132H in Chinese PCa patients is 0.6% (2/336). Of note, IDH1R132H-mutant PCa patients lacked other canonical genomic lesions (e.g., ERG rearrangement, PTEN deletion) that are common in most other PCa patients. The in vitro experiment suggested that IDH1R132H can promote proliferation of benign prostate epithelial cell RWPE-1 when under the situation of low cytokine. It could also promote migration capacity of RWPE-1 cells. Mechanistically, IDH1R132H was an important regulator of insulin-like growth factor 1receptor (IGF1R) by downregulating a set of microRNAs (miR-141-3p, miR-7-5p, miR-223-3p). These microRNAs were repressed by the alteration of epigenetic modification to decrease the enrichment of active marker H3K4me3 or to increase repressive marker H3K27me3 at their promoters. Collectively, we proposed a novel model for an IDH1R132H-microRNAs-IGF1R regulatory axis, which might provide insight into the function of IDH1R132H in PCa development.



http://ift.tt/2EN3COA

A Longitudinal Analysis of IDO and PDL1 Expression during Immune- or Targeted Therapy in Advanced Melanoma

Publication date: February 2018
Source:Neoplasia, Volume 20, Issue 2
Author(s): Lukas Krähenbühl, Simone M Goldinger, Joanna Mangana, Katrin Kerl, Ines Chevolet, Liève Brochez, Christine Horak, Mitch Levesque, Reinhard Dummer, Phil F Cheng
A deepened understanding of the cellular and molecular processes in the tumor microenvironment is necessary for the development of precision immunotherapy (IT). We simultaneously investigated CD3, PDL1, and IDO by immunohistochemistry in paired biopsies from various organs of 43 metastatic melanoma patients treated with IT and targeted therapy (TT). Intraindividual biopsies taken after a period of weeks to months demonstrate discordant results in 30% of the cases. Overlap of IDO and PDL1 increased after therapy. IT only marginally impacted PDL1 expression over time in contrast to TT. Standardized repeated assessments of multiple immune markers in repeated biopsies will generate detailed insights in melanoma's immune evolution and adaption during therapies and might be used to support treatment decisions.



http://ift.tt/2FKAYPA

Scholar : These new articles for Creative Industries Journal are available online

The online platform for Taylor & Francis Online content New for Creative Industries Journal and online now on Taylor & Francis Online: Original Articles Creative industries and economic growth: stability of creative products exports earnings Raul Gouvea & Gautam Vora Pages: 1-32 | DOI: 10.1080/17510694.2017.1416529 Browse this free access collection on: Communication, Media and Culture in Asia. To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Metabolic syndrome and its components among Korean submariners: a retrospective cross-sectional study

Abstract

Purpose

Metabolic syndrome (MetS) is a cluster of inter-related risk factors for cardiovascular disease and diabetes. Although submariners tend to be exposed to unhealthy environmental factors, such as a confined work environment, physical inactivity, and circadian disruption, little is known regarding whether the risks of MetS and its components are associated with submarine service. The present study aimed to evaluate the risks of MetS and its components among submariners.

Methods

A total of 5090 subjects (513 submariners and 4577 non-submariners) were included in the present study. We calculated the age-standardized and age-specific prevalences of MetS. The associations between submarine service and the risks of MetS and its components were evaluated using logistic regression analysis after adjusting for age, service rank, and lifestyle factors.

Results

The age-standardized prevalences of MetS were 17.6 and 15.1% among submariners and non-submariners, respectively. Compared to non-submariners, submariners had higher risks of MetS (odds ratio [OR] 1.31, 95% confidence interval [CI] 1.02, 1.68), low high-density lipoprotein cholesterol (OR 1.73, 95% CI 1.36, 2.20), and impaired fasting glucose (OR 1.46, 95% CI 1.21, 1.76). When we stratified the subjects according to physical activity, an increased risk of elevated blood pressure associated with submarine service was evident only in the subgroup with moderate or vigorous physical activity (P for interaction = 0.006).

Conclusion

Submariners had higher risks of MetS and some MetS components, compared to non-submariners. These findings suggest that special efforts are needed to prevent and manage MetS among individuals who are expected to be exposed to submarine environment.

http://ift.tt/2Db6Uuy

Fasting Blood Glucose Level in Locally Advanced Non-Small Cell Lung Cancer: a New Prognostic Factor?

Abstract

Hyperglycemia may lead to proliferation, invasion, apoptosis inhibition, migration, and eventually metastasis of cancer cells by several mechanisms. In this study, the effect of hyperglycemia on overall survival (OS), disease-free survival (DFS), and locoregional recurrence (LRR) was investigated in NSCLC. One stage IIIA-IIIB NSCLC patient treated with chemoradiotherapy between 2010 and 2015 was enrolled. Fasting blood glucose (FBG) levels were recorded in pre-treatment, treatment, and post-treatment periods. Median age was 54 years (51–62). Fifty-two patients had squamous cell carcinoma (SCC); 19 had adenocarcinoma. Median follow-up was 19 (11–30), median survival was 19 (13–24), and DFS was 9 (7–11) months. Diabetic patients had shorter survival than non-diabetics 12 (95%CI, 10–14) vs. 25 months (95%CI,18–32), p = 0.005. Number of patients with LRR was also higher in diabetics compared to non-diabetics (8/12 vs. 11/37, p = 0.039). OS was shorter in patients with hyperglycemic-FBG and diabetic-FBG levels in pre-treatment period (log-rank p = 0.03 and 0.023, respectively). Diabetic-FBG level in pre-treatment period was found to be the only independent risk factor for survival. In subgroup analysis, these differences were apparent in SCC (log-rank p = 0.009 for hyperglicemic, log-rank p = 0.017 for diabetic-FBG). LRR was 68% in patients with diabetic-FBG, 36.5% in patients with non-diabetic-FBG in post-treatment period (p = 0.015). Patients with LRR had significantly higher median FBG value in post-treatment period compared to non-relapsing patients, 138 mg/dL (119–228) and 111 mg/dL (99–164), respectively (p = 0.022). The patients with hyperglycemic and diabetic-FBG levels in pre-treatment period had shorter survival compared to normoglycemic ones. The patients with diabetic-FBG level in post-treatment period had higher LRR, and relapsing patients had higher FBG levels in post-treatment period.

http://ift.tt/2B7a40z

Harnessing a Different Dependency: How to Identify and Target Androgen Receptor-Positive Versus Quadruple-Negative Breast Cancer

Abstract

The androgen receptor (AR) is a promising therapeutic target for a subset of triple-negative breast cancers (TNBCs) in which AR is expressed. However, the mechanistic action of AR and the degree to which primary and metastatic tumors depend on AR, both before and after conventional treatment, remain to be defined. We discuss preclinical and clinical data for AR+ TNBC, the difficulties in monitoring AR protein levels, new methods for determining AR status, the influence of AR on "stemness" in the context of TNBC, the role of combined inhibition of sex steroid production and AR, and the role of AR in regulation of the immune system. Although the exact role of AR in subsets of TNBC is still being characterized, new therapies that target AR and the production of androgens may provide additional options for patients with TNBC for whom chemotherapy is currently the sole treatment option.

http://ift.tt/2DfNBV7

Delayed Initial Radioiodine Therapy Related to Incomplete Response in Low- to Intermediate-Risk Differentiated Thyroid Cancer

Abstract

Objective

Whether the initiating time of radioiodine (RAI) therapy will affect the clinical outcome in differentiated thyroid cancer (DTC) remains controversial. The objective of this study was to evaluate the impact of RAI therapy initiating time on response to initial therapy in low- to intermediate-risk DTC

Methods

A total of 235 consecutive patients with low- to intermediate-risk DTC were retrospectively reviewed. According to the time interval between thyroidectomy and RAI therapy, patients were divided into Group 1 (interval < 3 months, n=187) and Group 2 (interval ≥ 3 months, n=48). Response to RAI therapy was evaluated as excellent, indeterminate, biochemical incomplete, or structural incomplete response (ER, IDR, BIR, or SIR) with a median follow-up of 780 days. The univariate and multivariate analyses were further conducted to identify factors associated with incomplete response (IR, including BIR and SIR)

Results

Response to initial therapy was significantly different between 2 groups (P<0.05), after excluding the impact of other risk factors (age, gender, histological type, status of T and N, RAI dose, thyrotropin, stimulated thyroglobulin and follow-up time). A significantly higher IR rate (18.8% vs 4.3%, P=0.001) and a lower ER proportion (62.5% vs 78.1%, P=0.027) were observed in Group2. By univariate analysis, both T and N status, stimulated thyroglobulin and time interval were significant risk factors for IR (P<0.05). Multivariate analysis demonstrated that the time interval was an independent risk factors for IR (P=0.008)

Conclusions

Delayed initial RAI therapy (≥3 months after thyroidectomy) related to incomplete response in low- to intermediate-risk DTC.

This article is protected by copyright. All rights reserved.

http://ift.tt/2EMnWQ6

Draft genome sequence of Xylaria sp., the causal agent of taproot decline of soybean in the southern United States

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Sandeep Sharma, Alex Z. Zaccaron, John B. Ridenour, Tom W. Allen, Kassie Conner, Vinson P. Doyle, Trey Price, Edward Sikora, Raghuwinder Singh, Terry Spurlock, Maria Tomaso-Peterson, Tessie Wilkerson, Burton H. Bluhm
The draft genome of Xylaria sp. isolate MSU_SB201401, causal agent of taproot decline of soybean in the southern U.S., is presented here. The genome assembly was 56.7Mb in size with an L50 of 246. A total of 10,880 putative protein-encoding genes were predicted, including 647 genes encoding carbohydrate-active enzymes and 1053 genes encoding secreted proteins. This is the first draft genome of a plant-pathogenic Xylaria sp. associated with soybean. The draft genome of Xylaria sp. isolate MSU_SB201401 will provide an important resource for future experiments to determine the molecular basis of pathogenesis.



http://ift.tt/2Dlv4WF

Spatially and temporally continuous estimates of annual total nitrogen deposition over North America, 1860–2013

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Robbie A. Hember
This report describes the North American Climate Integration and Diagnostics – Nitrogen Deposition Version 1 (NACID-NDEP1) database. The database contains estimates of annual total nitrogen (N) deposition for the purpose of supporting terrestrial ecosystem modelling in North America. It was constructed at 1-km resolution with coverage of Alaska, Canada, and the conterminous U.S., with continuous annual coverage from 1860 to 2013. Estimates were produced by acquiring and compiling best-available data sources: Wet N deposition was estimated from interpolation of monthly ammonium and nitrate concentration measurements and from grids of monthly precipitation. Dry N deposition was estimated from satellite measurements of ammonium and nitrogen oxides. Total N deposition for the pre-industrial era was derived from previous modelling studies. As these source datasets covered different time periods, several assumptions were required to produce a continuous record.



http://ift.tt/2mBawPJ

Data set on the bioprecipitation of sulfate and trivalent arsenic by acidophilic non-traditional sulfur reducing bacteria

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Letícia Paiva de Matos, Patrícia Freitas Costa, Mariana Moreira, Paula Cristine Silva Gomes, Silvana de Queiroz Silva, Leandro Vinícius Alves Gurgel, Mônica Cristina Teixeira
Data presented here are related to the original paper "Simultaneous removal of sulfate and arsenic using immobilized non-traditional sulfate reducing bacteria (SRB) mixed culture and alternative low-cost carbon sources" published by same authors (Matos et al., 2018) [1]. The data set here presented aims to facilitate this paper comprehension by giving readers some additional information. Data set includes a brief description of experimental conditions and the results obtained during both batch and semi-continuous reactors experiments. Data confirmed arsenic and sulfate were simultaneously removed under acidic pH by using a biological treatment based on the activity of a non-traditional sulfur reducing bacteria consortium. This microbial consortium was able to utilize glycerol, powdered chicken feathers as carbon donors, and proved to be resistant to arsenite up to 8.0mgL⁻¹. Data related to sulfate and arsenic removal efficiencies, residual arsenite and sulfate contents, pH and Eh measurements obtained under different experimental conditions were depicted in graphical format.Refers to http://ift.tt/2mCi2tH



http://ift.tt/2DlLvSV

MCIndoor20000: A fully-labeled image dataset to advance indoor objects detection

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Fereshteh S. Bashiri, Eric LaRose, Peggy Peissig, Ahmad P. Tafti
A fully-labeled image dataset provides a unique resource for reproducible research inquiries and data analyses in several computational fields, such as computer vision, machine learning and deep learning machine intelligence. With the present contribution, a large-scale fully-labeled image dataset is provided, and made publicly and freely available to the research community. The current dataset entitled MCIndoor20000 includes more than 20,000 digital images from three different indoor object categories, including doors, stairs, and hospital signs. To make a comprehensive dataset addressing current challenges that exist in indoor objects modeling, we cover a multiple set of variations in images, such as rotation, intra-class variation plus various noise models. The current dataset is freely and publicly available at http://ift.tt/2mBap6L.



http://ift.tt/2Dn28gQ

Dataset demonstrating effects of momentum transfer on sizing of current collector for lithium-ion batteries during laser cutting

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Dongkyoung Lee, Jyotirmoy Mazumder
Material properties of copper and aluminum required for the numerical simulation are presented. Electrodes used for the (paper) are depicted. This study describes the procedures of how penetration depth, width, and absorptivity are obtained from the simulation. In addition, a file format extracted from the simulation to visualize 3D distribution of temperature, velocity, and melt pool geometry is presented.



http://ift.tt/2DlPxKY

Fibroblast and keratinocyte gene expression following exposure to the extracts of holy basil plant (Ocimum tenuiflorum), malabar nut plant (Justicia adhatoda), and mblic myrobalan plant (Phyllanthus emblica)

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Takao Someya, Katsura Sano, Kotaro Hara, Yoshimasa Sagane, Toshihiro Watanabe, R.G.S. Wijesekara
This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of holy basil plant (Ocimum tenuiflorum), sri lankan local name "maduruthala", 0.1% and 0.01% extracts of malabar nut plant (Justicia adhatoda), sri lankan local name "adayhoda" and 0.003% and 0.001% extracts of emblic myrobalan plant (Phyllanthus emblica), sri lankan local name "nelli", harvested in Sri Lanka. For fibroblasts, the dataset includes expression profiles for genes encoding hyaluronan synthase 1 (HAS1), hyaluronan synthase 2 (HAS2), hyaluronidase-1 (HYAL1), hyaluronidase-2 (HYAL2), versican, aggrecan, CD44, collagen, type I, alpha 1 (COL1A1), collagen, type III, alpha 1 (COL3A1), collagen, type VII, alpha 1 (COL7A1), matrix metalloproteinase 1 (MMP1), acid ceramidase, basic fibroblast growth factor (bFGF), fibroblast growth factor-7 (FGF7), vascular endothelial growth factor (VEGF), interleukin-1 alpha (IL-1α), cyclooxygenase-2 (cox2), transforming growth factor beta (TGF-β), and aquaporin 3 (AQP3). For keratinocytes, the expression profiles are for genes encoding HAS1, HAS2, HYAL1, HYAL2, versican, CD44, IL-1α, cox2, TGF-β, AQP3, Laminin5, collagen, type XVII, alpha 1 (COL17A1), integrin alpha-6 (ITGA6), ceramide synthase 3 (CERS3), elongation of very long chain fatty acids protein 1 (ELOVL1), elongation of very long chain fatty acids protein 4 (ELOVL4), filaggrin (FLG), transglutaminase 1 (TGM1), and keratin 1 (KRT1). The expression profiles are provided as bar graphs.



http://ift.tt/2mDUGUq

High-resolution dataset for building energy management systems applications

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Wessam El-Baz, Johannes Honold, Lukas Hardi, Peter Tzscheutschler
Modelling and optimization of energy management systems (EMS) require different data types for operation and validation. In this article, a multi-purpose dataset is provided for EMS applications. It includes PV measurement data for the PV generation and prediction algorithms associated with EMS systems. Weather data has also been measured at the same location for the optimization of PV prediction algorithms and other applications such as building model simulations. Moreover, the dataset contains detailed measurements of a seminar room where not only temperatures have been measured, but also user feedback for comfort assessment. All documented measurements have been gathered at the same location in Munich, Germany.



http://ift.tt/2DluVCB

Learning analytics for smart campus: Data on academic performances of engineering undergraduates in Nigerian private university

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Segun I. Popoola, Aderemi A. Atayero, Joke A. Badejo, Temitope M. John, Jonathan A. Odukoya, David O. Omole
Empirical measurement, monitoring, analysis, and reporting of learning outcomes in higher institutions of developing countries may lead to sustainable education in the region. In this data article, data about the academic performances of undergraduates that studied engineering programs at Covenant University, Nigeria are presented and analyzed. A total population sample of 1841 undergraduates that studied Chemical Engineering (CHE), Civil Engineering (CVE), Computer Engineering (CEN), Electrical and Electronics Engineering (EEE), Information and Communication Engineering (ICE), Mechanical Engineering (MEE), and Petroleum Engineering (PET) within the year range of 2002–2014 are randomly selected. For the five-year study period of engineering program, Grade Point Average (GPA) and its cumulative value of each of the sample were obtained from the Department of Student Records and Academic Affairs. In order to encourage evidence-based research in learning analytics, detailed datasets are made publicly available in a Microsoft Excel spreadsheet file attached to this article. Descriptive statistics and frequency distributions of the academic performance data are presented in tables and graphs for easy data interpretations. In addition, one-way Analysis of Variance (ANOVA) and multiple comparison post-hoc tests are performed to determine whether the variations in the academic performances are significant across the seven engineering programs. The data provided in this article will assist the global educational research community and regional policy makers to understand and optimize the learning environment towards the realization of smart campuses and sustainable education.



http://ift.tt/2mE8EFB