Author: Oliver, Zoe J.; Cristino, Filipe; Roberts, Mark V.; Pegna, Alan J.; Leek, E. Charles
DOI: 10.1037/xhp0000444
Publication Date: POST AUTHOR CORRECTIONS, 2017
http://ift.tt/2C3nG21
Σάββατο 17 Φεβρουαρίου 2018
(Not) Eating for the environment: The impact of restaurant menu design on vegetarian food choice
Publication date: 1 June 2018
Source:Appetite, Volume 125
Author(s): Linda Bacon, Dario Krpan
Previous research has shown that restaurant menu design can influence food choices. However, it remains unknown whether such contextual effects on food selection are dependent on people's past behavior. In the present study, we focused on vegetarian food choices, given their important implications for the environment, and investigated whether the influence of different restaurant menus on the likelihood of selecting a vegetarian dish is moderated by the number of days on which people reported eating only vegetarian food during the previous week. In an online scenario, participants were randomly assigned to four different restaurant menu conditions—control (all dishes presented in the same manner), recommendation (vegetarian dish presented as chef's recommendation), descriptive (more appealing description of vegetarian dish), and vegetarian (vegetarian dishes placed in a separate section)—and ordered a dish for dinner. The results showed that the recommendation and descriptive menus increased the likelihood of vegetarian dish choices for infrequent eaters of vegetarian foods, whereas these effects tended to reverse for those who ate vegetarian meals more often. The vegetarian menu had no impact on the infrequent vegetarian eaters' choice but backfired for the frequent vegetarian eaters and made them less likely to order a vegetarian dish. These findings indicate that people's past behavior is an important determinant of the impact of nudging on food choices, and that achieving sustainable eating may require more personalized interventions.
http://ift.tt/2BzTWbW
The Montreal Children’s Hospital Feeding Scale: Relationships with parental report of child eating behaviours and observed feeding interactions
Publication date: 1 June 2018
Source:Appetite, Volume 125
Author(s): Samantha Rogers, Maria Ramsay, Jackie Blissett
Feeding problems are common, with implications for nutrition, growth and family stress, placing burden on primary care services. The Montreal Children's Hospital Feeding Scale (MCHFS) is a quick and reliable measure of feeding problems for clinical settings, but there is little examination of its relationship to commonly used research measures of parental feeding practice, child eating behaviour and observations of parent-infant interaction at mealtimes. We examined the relationships between the MCHFS, demographics and early feeding history, weight across the first year, parental report of feeding practices and child eating behaviours, and observations of maternal-infant feeding interaction at 1 year. The MCHFS, Comprehensive Feeding Practices Questionnaire (CFPQ) and Child Eating Behaviour Questionnaire (CEBQ) were completed by 69 mothers when their infants were 1-year-old (37 male, 32 female). Infant weight was measured at 1 week, 1 month, 6 months and 1 year. Mothers were observed feeding their infants at 1 year. The MCHFS was reliable (Cronbach's alpha = .90) and showed significant overlap with other measures of feeding and eating. Potential feeding problems were identified in 10 of the children (14%) reflecting similar rates in other community samples. Higher MCHFS scores were associated with lower birthweight and weight across the first year, greater satiety responsiveness, fussiness and slowness in eating, lower enjoyment of food and food responsiveness, and less observed infant food acceptance. Parents of infants with more feeding problems reported less encouragement of balance and variety in their children's diets. Conclusion: MCHFS showed good criterion validity with other parental report measures of eating and observations of mealtime interactions. MCHFS may be a useful tool for researching feeding problems in community samples.
http://ift.tt/2EBnN6G
Erratum
Publication date: Available online 17 February 2018
Source:Practical Radiation Oncology
http://ift.tt/2ExKYPf
The paleoecology of Pleistocene birds from Middle Bed II, at Olduvai Gorge, Tanzania, and the environmental context of the Oldowan-Acheulean transition
Publication date: Available online 17 February 2018
Source:Journal of Human Evolution
Author(s): Kari A. Prassack, Michael C. Pante, Jackson K. Njau, Ignacio de la Torre
Fossil bird data (community composition and taphonomic profiles) are used here to infer the environmental context of the Oldowan-Acheulean transitional period at Olduvai Gorge, Tanzania. This is the first comprehensive report on the Middle Bed II avifauna and includes fossils excavated by the Olduvai Geochronology and Archaeology Project (OGAP) and recently rediscovered fossils collected by Mary Leakey. Crane, ibis, darter, owl, raptor, crow, and vulture are reported from Bed II for the first time. The presence of these taxa, absent earlier in this Bed, point to a general opening and drying of the landscape with grassland and open woodland expansion. Taxa associated with dense, emergent wetland vegetation, such as dabbling ducks and rails, are uncommon and less diverse than earlier in Bed II. This suggests more mature wetlands with clearer waters. Cormorants continue to be common, but are less diverse. Cormorants and other roosting taxa provide evidence of trees in the area. Compared to lowermost Bed II, the Middle to Upper Bed II landscape is interpreted here as more open and drier (but not necessarily more arid), with matured wetlands, scattered trees, and a greater expansion of grasslands.
http://ift.tt/2EOcuHi
DNA polymerase I proofreading exonuclease activity is required for endonuclease V repair pathway both in vitro and in vivo
Publication date: Available online 17 February 2018
Source:DNA Repair
Author(s): Kang-Yi Su, Liang-In Lin, Steven D. Goodman, Rong-Syuan Yen, Cho-Yuan Wu, Wei-Chen Chang, Ya-Chien Yang, Wern-Cherng Cheng, Woei-horng Fang
Deamination of adenine can occur spontaneously under physiological conditions to generate the highly mutagenic lesion, deoxyinosine (hypoxanthine deoxyribonucleotide, dI). In DNA, dI preferably pairs with cytosine rather than thymine and results in A:T to G:C transition mutations after DNA replication. The deamination of adenine is enhanced by ROS from exposure of DNA to ionizing radiation, UV light, nitrous acid, or heat. In Escherichia coli, dI repair is initiated by endonuclease V (endo V; nfi gene product) nicking but a complete repair mechanism has yet to be elucidated. Using in vitro minimum component reconstitution assays, we previously showed that endo V, DNA polymerase I (pol I), and E. coli DNA ligase were sufficient to repair this dI lesions efficiently and that the 3′-5′ exonuclease of pol I is essential. Here we employed a phagemid-based T-I substrate mimicking adenine deamination product to demonstrate pol I proofreading exonuclease is required by the endo V repair pathway both in vitro and in vivo. In vivo we found that the repair level of an nfi mutant (11%) was almost 8-fold lower than the wild type (87%). while the polA-D424A strain, a pol I mutant defective in 3′-5′ exonuclease, showed a high repair level similar to wild type (both more than 80%). Using additional C-C mismatch as strand discrimination marker we found that the high level of dI removal in polA-D424A was due to strand loss (more than 60%) associated with incomplete repair. Thus, pol I proofreading exonuclease is the major function responsible for dI lesion removal after endoV nicking both in vitro and in vivo. Finally, using MALDI-TOF to analyze single-nucleotide extension product we show that the pol I proofreading exonuclease excises only 2-nt 5′ upstream of endo V incision site further honing the role of pol I in the endoV dI dependent repair pathway.
http://ift.tt/2o49pJR
Detection of acute and long-term effects of concussion: dual-task gait balance control vs. computerized neurocognitive test
Publication date: Available online 16 February 2018
Source:Archives of Physical Medicine and Rehabilitation
Author(s): David R. Howell, Louis R. Osternig, Li-Shan Chou
ObjectiveOur aim was to examine the acute (within 72 hours of injury) and long-term (2 months post-injury) independent associations between objective dual-task gait balance and neurocognitive measurements among adolescents and young adults with a concussion and matched controls.DesignLongitudinal case-controlSettingMotion analysis laboratoryParticipantsParticipants who sustained a concussion underwent a dual-task gait analysis and computerized neurocognitive testing within 72 hours of injury and again 2 months later. Uninjured controls also completed the same test protocol in similar time increments.InterventionsNot applicableMain Outcome MeasuresWe compared dual-task gait balance control and computerized neurocognitive test performance between groups using independent samples t-tests. Multivariable binary logistic regression models were then constructed for each testing time to determine the association between group membership (concussion vs. control), dual-task gait balance control, and neurocognitive function.ResultsNinety-five participants completed the study, 51 who sustained a concussion (mean age= 17.5±3.3 years; 71% male) and 44 controls (mean age= 17.7±2.9 years; 72% male). Medial-lateral center-of-mass displacement during dual-task gait was independently associated group membership at the initial test (adjusted odds ratio [aOR]= 2.432, 95% CI= 1.269-4.661) and 2 month follow-up test (aOR= 1.817, 95% CI= 1.014-3.256) tests. Visual memory composite scores were significantly associated with group membership at the initial hour post-injury time point (aOR= 0.953, 95% CI= 0.833-0.998). However, the combination of computerized neurocognitive test variables did not predict dual-task gait balance control for concussion participants, and no single neurocognitive variable was associated with dual-task gait balance control at either testing time.ConclusionsDual-task assessments concurrently evaluating gait and cognitive performance may allow for the detection of persistent deficits beyond those detected by computerized neurocognitive deficits alone.
http://ift.tt/2o5Anke
Home-based neuromuscular electrical stimulation as an add-on to pulmonary rehabilitation does not provide further benefits in patients with chronic obstructive pulmonary disease: A multicenter randomized trial
Publication date: Available online 16 February 2018
Source:Archives of Physical Medicine and Rehabilitation
Author(s): Tristan Bonnevie, Francis-Edouard Gravier, David Debeaumont, Catherine Viacroze, Jean-François Muir, Antoine Cuvelier, Marie Netchitaïlo, Anne Laure Roy, Jean Quieffin, Marie-Hélène Marques, Clément Médrinal, Johan Dupuis, Catherine Tardif
ObjectiveTo assess the additional effect of a home-based neuro muscular electrical stimulation (NMES) program as an add-on to pulmonary rehabilitation (PR), on functional capacity in subjects with chronic obstructive pulmonary disease (COPD).DesignSingle-blind, multicenter randomized trial.SettingThree PR centers.ParticipantsSubjects with severe to very severe COPD referred for PR (n=73; median FEV1, 1 (0.8-1.4) L). Twenty-two subjects discontinued the study but only one drop-out was related to the intervention (leg discomfort).InterventionSubjects were randomly assigned to either PR plus quadricipital home-based NMES (35Hz, 30min, five time per week) or PR without NMES for 8 weeks.Main outcome measureThe six-minute walk test was used to assess functional capacity.ResultsEighty-two percent of the scheduled NMES sessions were performed. In the whole sample, there were significant increases in the distance walked during the 6MWT (p<0.01), VO2peak (p=0.02), Wmax (p<0.01), mMRC (p<0.01) and SGRQ total score (p=0.01). There was no significant difference in the magnitude of change for any outcome between groups.ConclusionsHome-based NMES as an add-on to PR did not result in further improvements in subjects with severe to very severe COPD, moreover, it may have been a burden for some patients.
http://ift.tt/2oezwgu
Devices for Home Detection of Obstructive Sleep Apnea: A Review
One of the most common sleep-related disorders is obstructive sleep apnea, characterized by a reduction of airflow while breathing during sleep and cause significant health problems. This disorder is mainly diagnosed in sleep labs with polysomnography, involving high costs and stress for the patient. To address this situation multiple systems have been proposed to conduct the examination and analysis in the patient's home, using sensors to detect physiological signals that are examined by algorithms.
http://ift.tt/2C31vJ9
Asomatognosia
Publication date: Available online 17 February 2018
Source:Cortex
Author(s): Paul M. Jenkinson, Valentina Moro, Aikaterini Fotopoulou
http://ift.tt/2ExAQ4J
Ternary interfacial superstructure enabling extraordinary hydrogen evolution electrocatalysis
Publication date: Available online 17 February 2018
Source:Materials Today
Author(s): Hongliang Jiang, Yunxiang Lin, Bingxu Chen, Youkui Zhang, Hengjie Liu, Xuezhi Duan, De Chen, Li Song
Realizing large-scale electrochemical hydrogen evolution in alkaline and neutral media by robust and non-noble-metal heterogeneous catalysts is highly ambitious due to the sluggish reaction kinetics at low H+ conditions. Herein, highly efficient hydrogen evolution reaction (HER) catalysts, comprising Ni, NiO clusters, and defective carbon, are successfully constructed via a facile and large-scale route. Multiple synchrotron radiation-based X-ray spectroscopic characterizations, combining high-resolution transmission electron microscopy measurements, indicate the formation of ternary interfacial superstructure with intimate interfacial coupling through abundant NiOC bonds. Impressively, the optimized catalyst loaded onto the usual glass carbon electrode exhibits exceptional catalytic activities with overpotentials of 64 and 76 mV to reach 10 mA cm−2 in 1 M KOH and 1 M phosphate buffer solution (PBS), respectively, representing one of the best non-noble-metal HER electrocatalysts to date. Insights into the metal/oxide interfacial effects through density functional theory calculations reveal that the interface sites could efficiently lower the energy barrier of the rate-determining step (RDS), contributing to the fast reaction kinetics. This work not only provides comprehensive insights into interfacial feature of highly active HER catalysts but also broadens the fundamental understanding of interfacial effects toward HER catalysis.
Graphical abstract
http://ift.tt/2EPwJV6
Feature-guided attentional capture cannot be prevented by spatial filtering
Publication date: Available online 16 February 2018
Source:Biological Psychology
Author(s): Nick Berggren, Martin Eimer
Feature-based control processes guide attention towards objects with target features in visual search. While these processes are assumed to operate globally across the entire visual field, it remains controversial whether target-matching objects at task-irrelevant locations can be excluded from attentional selection, especially when spatial attention is already narrowly focused elsewhere. We investigated whether probe stimuli at irrelevant lateral locations capture attention when they precede search displays where targets are defined either by a specific feature (colour or orientation) or by a colour/orientation conjunction by measuring N2pc components (an electrophysiological marker of attentional target selection) to these probes. Reliable N2pcs were triggered by probes not only in the feature search tasks but also when participants searched for feature conjunctions, in spite of the fact that conjunction search requires focal spatial attention. Analogous N2pc results were found in the absence of any spatial uncertainty about the location of conjunctively defined targets, which always appeared at fixation. These results show that rapid attentional capture by objects with target-matching features cannot be prevented by top-down spatial filtering mechanisms, and confirm that feature-based attentional guidance processes operate in a spatially global fashion.
http://ift.tt/2BzXyuu
Editorial Board
Publication date: February 2018
Source:Critical Reviews in Oncology/Hematology, Volume 122
http://ift.tt/2Gp97E9
Electrokinetic-Fenton remediation of organochlorine pesticides from historically polluted soil
Abstract
Soil contamination by persistent organic pollutants (POPs) poses a great threat to historically polluted soil worldwide. In this study, soils were characterized, and organochlorine pesticides contained in the soils were identified and quantified. Individual electrokinetic (IE), EK-Fenton-coupled technologies (EF), and enhanced EK-Fenton treatment (E-1, E-2, and E-3) were applied to remediate soils contaminated with hexachloro-cyclohexane soprocide (HCH) and dichloro-diphenyl-trichloroethane (DDT). Variation of pH, electrical conductivity, and electroosmotic flow was evaluated during the EK-Fenton process. The IE treatment showed low removal efficiency for HCHs (30.5%) and DDTs (25.9%). In the EF treatment, the highest removal level (60.9%) was obtained for α-HCH, whereas P,P-DDT was the lowest (40.0%). Low solubility of pollutants impeded the HCH and DDT removal. After enhanced EK-Fenton treatment, final removal of pollutants decreased as follows: β-HCH (82.6%) > γ-HCH (81.6%) > α-HCH (81.2%) > δ-HCH (80.0%) > P,P-DDD (73.8%) > P,P-DDE (73.1%) > P,P-DDT (72.6%) > O,P-DDT (71.5%). The results demonstrate that EK-Fenton is a promising technology for POP removal in historically polluted soil.
http://ift.tt/2o6ruqK
Effect of remote myofascial release on hamstring flexibility in asymptomatic individuals – A randomized clinical trial
Publication date: Available online 17 February 2018
Source:Journal of Bodywork and Movement Therapies
Author(s): Durga Girish Joshi, Ganesh Balthillaya, Anupama Prabhu
BackgroundThe existence of continuity between fascia and muscles that may be anatomically distant from each other is emphasized in the tensegrity principle. Despite evidence from in vitro studies, there is a dearth of literature concerning the in vivo behavior of these connections.AimTo compare the effect of Static Stretching (SS) of hamstrings with remote Myofascial Release (MFR) (bilateral plantar fascia and suboccipital region) and a combination of SS and remote MFR on hamstring flexibility. The secondary aim of this study was to investigate the difference between therapist administered and self-administered interventions.DesignThree arm assessor-blinded Randomized Clinical Trial (RCT).ParticipantsFifty-eight asymptomatic participants (16 Males; Mean age 22.69 ± 2.65 years).MethodParticipants with tight hamstrings defined by a passive Knee Extension Angle (KEA) > 20° were included in the study and were assigned to one of the three groups. Group A (n = 19) was SS, group B (n = 20) was remote MFR, group C (n = 19) was a combination group who received both SS and remote MFR. Seven sessions of therapist administered intervention were delivered over a period of 10 days, which was followed by a 2-week self-administered home program. KEA and Sit and Reach Test (SRT) were used as outcomes and measurements were performed at baseline, end of the seventh session and after atwo-week follow-up.ResultsThe results demonstrated that hamstring flexibility improved in all three groups after therapist administered interventions (p < 0.05), whereas, group C demonstrated additional benefits. None of the groups showed a statistically significant (p > 0.05) change in the KEA with self-intervention.ConclusionThe findings of this study indicated that all three interventions were effective in improving hamstring flexibility in young asymptomatic individuals when performed by the therapist.
http://ift.tt/2FawPVj
Scholar : The American Journal of Drug and Alcohol Abuse, Volume 44, Issue 2, 2018 is now available online on Taylor & Francis Online
|
Scholar : Communication Design, Volume 5, Issue 1-2, May - November 2017 is now available online on Taylor & Francis Online
@media screen and (max-width:400px) { .two .column, .two .left, .two .right{ max-width: 100% !important; } } @media screen and (min-width: 401px) and (max-width:620px){ .two .column, .two .left, .two .right { max-width: 100% !important; } }
|
Scholar : Canadian Journal of Latin American and Caribbean Studies / Revue canadienne des études latino-américaines et caraïbes, Volume 43, Issue 1, March 2018 is now available online on Taylor & Francis Online
@media screen and (max-width:400px) { .two .column, .two .left, .two .right{ max-width: 100% !important; } } @media screen and (min-width: 401px) and (max-width:620px){ .two .column, .two .left, .two .right { max-width: 100% !important; } }
Lead facilitates foci formation in a Balb/c-3T3 two-step cell transformation model: role of Ape1 function
Abstract
Several possible mechanisms have been examined to gain an understanding on the carcinogenic properties of lead, which include among others, mitogenesis, alteration of gene expression, oxidative damage, and inhibition of DNA repair. The aim of the present study was to explore if low concentrations of lead, relevant for human exposure, interfere with Ape1 function, a base excision repair enzyme, and its role in cell transformation in Balb/c-3T3. Lead acetate 5 and 30 μM induced APE1 mRNA and upregulation of protein expression. This increase in mRNA expression is consistent throughout the chronic exposure. Additionally, we also found an impaired function of Ape1 through molecular beacon-based assay. To evaluate the impact of lead on foci formation, a Balb/c-3T3 two-step transformation model was used. Balb/c-3T3 cells were pretreated 1 week with low concentrations of lead before induction of transformation with n-methyl-n-nitrosoguanidine (MNNG) (0.5 μg/mL) and 12-O-tetradecanoylphorbol-13-acetate (TPA) (0.1 μg/mL) (a classical two-step protocol). Morphological cell transformation increased in response to lead pretreatment that was paralleled with an increase in Ape1 mRNA and protein overexpression and an impairment of Ape1 activity and correlating with foci number. In addition, we found that lead pretreatment and MNNG (transformation initiator) increased DNA damage, determined by comet assay. Our data suggest that low lead concentrations (5, 30 μM) could play a facilitating role in cellular transformation, probably through the impaired function of housekeeping genes such as Ape1, leading to DNA damage accumulation and chromosomal instability, one of the most important hallmarks of cancer induced by chronic exposures.
http://ift.tt/2sBhxpY
Surface nanostructuring of titanium imparts multifunctional properties for orthopedic and cardiovascular applications
Publication date: 15 April 2018
Source:Materials & Design, Volume 144
Author(s): Sumit Bahl, Bhavya Tulasi Aleti, Satyam Suwas, Kaushik Chatterjee
Commercially pure titanium (cp-Ti) is a metallic biomaterial used in orthopedic and cardiovascular applications. Here, surface nanocrystalline cp-Ti produced by surface mechanical attrition treatment (SMAT) is shown to exhibit multifunctional properties for orthopedic and cardiovascular applications. Nanocrystallization simultaneously enhanced the stem cell response and fatigue resistance in simulated body fluid of cp-Ti collectively required for load bearing orthopedic applications. Stem cell attachment and proliferation was enhanced by 20% and number of cycles to failure increased by 15% after nanocrystallization. Nanocrystalline Ti was also found to be suitable for cardiovascular applications due to its improved hemocompatibility. A 40% reduction in attachment of platelets and their activation was noted on the surface of nanocrystalline Ti. While high surface hardness and compressive residual stress improved the corrosion-fatigue resistance, the biological response of stem cells and platelets was governed by the physico-electro-chemical properties of the surface oxide on cp-Ti. Modulation in properties of the oxide layer altered the protein adsorption, evaluated by means of electrochemical impedance spectroscopy and direct protein quantification thereby, augmenting the biological response. Taken together, it is demonstrated that surface nanocrystallization by SMAT is a promising step towards producing high performance Ti implants for orthopedic and cardiovascular applications.
Graphical abstract
http://ift.tt/2EzETBR
Εγγραφή σε:
Αναρτήσεις (Atom)
-
Ειδοποίηση Μελετητή:[ ωτα ] [HTML] Gender, identity and material: Film screening C Brand - 2017 ftypM4V *M4V M4A mp42isom*a┌moovlmvhd...
-
Publication date: September 2017 Source: Free Radical Biology and Medicine, Volume 110 Author(s): Lucía Fernández-del-Río, Anish Nag, Elen...
