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Τρίτη 12 Ιουνίου 2018

Anthropometric and body composition changes in smokers vs abstainers following an exercise-aided pharmacotherapy smoking cessation trial for women

Publication date: October 2018
Source:Addictive Behaviors, Volume 85
Author(s): Harry Prapavessis, Stefanie De Jesus, Lyndsay Fitzgeorge, Scott Rollo
IntroductionPost-cessation weight gain contributes to smoking relapse, especially for women. Furthermore, excess weight in the form of android or visceral fat is associated with metabolic health problems. For this study, a secondary analysis was conducted in 2015 to determine whether quitting status, achieved through a 14 week supervised exercise-aided nicotine replacement therapy (NRT) cessation program [Getting Physical on Cigarette Trial-2009 to 2013; Prapavessis, et al., 2016], affects anthropometric and body composition parameters in female smokers (N = 413, M age = 42.39 years).MethodsAnthropometric (weight and BMI) and body composition (% total body fat, % android fat, lean mass and visceral fat) indices were assessed at baseline and end of treatment. Smoking status was confirmed weekly from expired breath carbon monoxide. Adherence to exercise and NRT patch was calculated from the number of exercise sessions attended and patches worn to the number of exercise sessions offered and patches supplied, respectively.ResultsFactorial (smoking status) ANCOVAs controlling for baseline anthropometric and body composition parameters as well as adherence to exercise and NRT revealed significant differences in weight (p = .033; ɳp2 = 0.017) and BMI (p = .020; ɳp2 = 0.020) at week 14. This equated to abstainers weighing 1.26 kg more and having a 0.52 higher BMI than smokers. No significant differences were found for any of the body composition parameters at week 14 (ɳp2 range from 0.001–0.007).ConclusionsAbstainers gain modest weight compared to smokers. This weight gain is related to increases in lean mass and not total, android, or visceral fat.



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Suicidal ideation among adults with a recent sexual assault: Prescription opioid use and prior sexual assault

Publication date: October 2018
Source:Addictive Behaviors, Volume 85
Author(s): Amanda K. Gilmore, Christine K. Hahn, Anna E. Jaffe, Kate Walsh, Angela D. Moreland, Erin F. Ward-Ciesielski
IntroductionSexual assault (SA) is common, and recent sexual assault is associated with suicidal ideation and prescription opioid (PO) use. PO use is also associated with increased risk of suicidal ideation. The current study examined suicidal ideation among adults seeking medical and psychological follow-up care after a SA medical forensic examination based on PO use and prior SA.MethodsAdults (n = 60) who received a SA medical forensic exam at the emergency room within 120 h of a SA were invited to receive medical and psychological follow-up care, which included a questionnaire about current mental health symptoms.ResultsResults from a linear regression model revealed that more acute stress symptoms were associated with higher suicidal ideation. Further, there was a significant association between PO use and suicidal ideation among those with a prior SA such that those with a prior SA and who used POs reported more severe suicidal ideation than those with a prior SA who did not use POs.ConclusionsRoutine screening at the emergency department for PO use and prior SA may help prevention efforts for suicide among adults who recently experienced SA.



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Biological floating bed and bio-contact oxidation processes for landscape water treatment: simultaneous removal of Microcystis aeruginosa , TOC, nitrogen and phosphorus

Abstract

The aim of this study was to identify algicidal bacteria J25 against the Microcystis aeruginosa (90.14%), Chlorella (78.75%), Scenedesmus (not inhibited), and Oscillatoria (90.12%). Meanwhile, we evaluate the SOD activity and efficiency of denitrification characteristics with Acinetobacter sp. J25. A novel hybrid bioreactor combined biological floating bed with bio-contact oxidation (BFBO) was designed for treating the landscape water, and the average removal efficiencies of nitrate-N, ammonia-N, nitrite-N, TN, TP, TOC, and algal cells were 91.14, 50, 87.86, 88.83, 33.07, 53.95, and 53.43%, respectively. A 454-pyrosequencing technology was employed to investigate the microbial communities of the BFBO reactor samples. The results showed that Acinetobacter sp. J25 was the dominant contributor for effective removal of N, algal cells, and TOC in the BFBO reactor. And the relative abundance of Acinetobacter showed increase trend with the delay of reaction time.

Graphical abstract

Biological floating bed and bio-contact oxidation (BFBO) as a novel hybrid bioreactor designed for simultaneous removal Microcystis aeruginosa, TOC, nitrogen, and phosphorus. And high-throughput sequencing data demonstrated that Acinetobacter sp. J25 was the dominate species in the reactor and played key roles in the removal of N, TOC, and M. aeruginosa. Proposed reaction mechanism of the BFBO.


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Endoscopic-Assisted Radial Forearm Free Flap Harvest: A Novel Technique to Reduce Donor Site Morbidity

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J reconstr Microsurg
DOI: 10.1055/s-0038-1653983

Background The radial forearm free flap (RFFF) remains a workhorse flap but can have significant donor site morbidity. The authors developed a novel technique for endoscopic-assisted RFFF (ERFFF) harvest and hypothesized improved donor site morbidity. Methods A retrospective cohort study was conducted evaluating patients who underwent ERFFF or RFFF by a single surgeon for head and neck reconstruction between November 2011 and July 2016; outcomes and complications were compared. A telephone survey was conducted to assess patient satisfaction with donor site appearance and function. Results Twenty-seven ERFFF and 13 RFFF harvests were performed. The cephalic vein was less commonly incorporated in ERFFF patients compared with RFFF patients (3.70 and 38.46%, respectively, p = 0.0095). ERFFF patients had lower rates of wound healing complications (0% vs. 15.38%, p = 0.10) and perfusion-related complications than RFFF patients (3.70% vs. 23.08%, p = 0.092). Fewer ERFFF patients reported a desire for a more normal appearance (42.86% vs. 71.43%, p = 0.361). The ERFFF group had a higher functional score (64.29% vs. 44.44%, p = 0.101), reporting lower rates of associated discomfort (35.71% vs. 85.71%, p = 0.063). None of the differences in rates of complications or patient-reported outcomes between the groups reached statistical significance. Conclusion ERFFF is safe and effective alternative to RFFF, with similar operative time, similar pedicle safety, and elimination of the lengthy forearm incision. Unnecessary cephalic vein dissection can be avoided with endoscopic visualization of the venae comitantes. Further research with a larger sample size and better standardization is needed to assess effects on donor-site morbidity.
[...]

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Article in Thieme eJournals:
Table of contents  |  Abstract  |  Full text



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“High Risk Device Registries: Global Value, Costs, and Sustainable Funding.”

Well-designed implant registries have been shown to be a worthwhile investment, from both a health and economic perspective. However, many registries do not attain desirable capture rates or lack sufficient funding, potentially leading to premature termination. This study aims to provide information about rarely discussed, yet pivotal topics regarding the long-term survival of implant registries, focusing on costs, funding models, and the role of stakeholders.

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Use of Dual skin paddles Anterolateral Thigh Perforator flaps in Reconstruction of complex defect of the foot and ankle

Complex soft tissue defect around the ankle and foot still was a difficult reconstructive problem for orthopedic and plastic surgeons. This study describes our clinical experience with the application of dual skin paddles anterolateral thigh perforator (ALTP) flap for reconstruction of complex defects around the ankle and foot.

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Antibiotic resistance genes in China: occurrence, risk, and correlation among different parameters

Abstract

Antibiotic resistance has become a widely concerned issue due to the huge risk on the ecological environment and human health. China has the highest production and consumption of antibiotics than other countries. Thus, antibiotic resistance genes (ARGs) have been detected in various environmental settings (e.g., surface water, wastewater, sediment) in China. The occurrence of ARGs in these matrixes was summarized and discussed in this review. Sulfonamide resistance genes and tetracycline resistance genes were the most frequently detected ARGs in China. According to the abundance of these two classes of ARGs in the natural environment, sulfonamide resistance genes seem to be more stable than tetracycline resistance genes. Furthermore, the relationships between ARGs and antibiotics, antibiotic resistance bacteria (ARB), heavy metals, and environmental parameters (e.g., pH, organics) were also investigated. Specifically, relative abundance of total ARGs was found to correlate well with concentration of total antibiotics in aqueous phase but not in the solid phase (soil, sediment, sludge, and manure). As for relationship between ARGs and ARB, metals, and environmental parameters in different media, due to complex and variable environment, some exhibit positive correlation, some negative, while others no correlation at all. Three potential risks are discussed in the text: transmission to human, synergistic effect of different ARGs, and variability of ARGs. However, due to the complexity of the environment, more work is needed to establish a quantitative approach of ARG risk assessment, which can provide a theoretical support for the management of antibiotics and the protection of human health.



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Response to Alongi et al.

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Publication date: Available online 12 June 2018
Source:Radiotherapy and Oncology
Author(s): Hanne Tøndel, Jo Åsmund Lund, Arne Solberg




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Hematologic variables associated with brain failure in patients with small-cell lung cancer

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Publication date: Available online 12 June 2018
Source:Radiotherapy and Oncology
Author(s): Ryoko Suzuki, Xiong Wei, Pamela K. Allen, James W. Welsh, Ritsuko Komaki, Steven H. Lin
Background and purposeWe sought factors associated with the development of brain metastases after treatment of small cell lung cancer (SCLC) in patients without brain involvement at diagnosis.MethodsWe analyzed 293 patients with SCLC without brain metastases who received chemotherapy, thoracic radiation therapy (TRT), or both in 2001–2015. Pretreatment hematologic markers (platelet count, neutrophil count, lymphocyte count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and lactate dehydrogenase) and other clinical characteristics were evaluated for correlation with brain metastases–free survival (BMFS). Cutoffs were established with receiver operating characteristics curves. Factors significant in univariate analysis were used to build a multivariate Cox model for BMFS.ResultsMedian follow-up time was 14.3 months. Brain metastases developed in 115 patients (39%)—32% of those with low pretreatment platelet counts (PPC) (≤270 × 109/L) and 46% of those with high PPC (>270 × 109/L). Median BMFS time for all patients was 27.9 months. Two-year BMFS rates were worse for patients with high PPC (14.6% vs. 22.1% low, P = 0.009). High PPC was independently associated with inferior BMFS (P = 0.038), as were receipt of TRT <45 Gy and no prophylactic cranial irradiation (both P < 0.001).ConclusionsHigh PPC was associated with increased rates of brain metastasis in patients with SCLC with no evidence of brain disease at diagnosis.



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Artificial intelligence in radiation oncology: A specialty-wide disruptive transformation?

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Publication date: Available online 12 June 2018
Source:Radiotherapy and Oncology
Author(s): Reid F. Thompson, Gilmer Valdes, Clifton D. Fuller, Colin M. Carpenter, Olivier Morin, Sanjay Aneja, William D. Lindsay, Hugo J.W.L. Aerts, Barbara Agrimson, Curtiland Deville, Seth A. Rosenthal, James B. Yu, Charles R. Thomas
Artificial intelligence (AI) is emerging as a technology with the power to transform established industries, and with applications from automated manufacturing to advertising and facial recognition to fully autonomous transportation. Advances in each of these domains have led some to call AI the "fourth" industrial revolution [1]. In healthcare, AI is emerging as both a productive and disruptive force across many disciplines. This is perhaps most evident in Diagnostic Radiology and Pathology, specialties largely built around the processing and complex interpretation of medical images, where the role of AI is increasingly seen as both a boon and a threat. In Radiation Oncology as well, AI seems poised to reshape the specialty in significant ways, though the impact of AI has been relatively limited at present, and may rightly seem more distant to many, given the predominantly interpersonal and complex interventional nature of the specialty. In this overview, we will explore the current state and anticipated future impact of AI on Radiation Oncology, in detail, focusing on key topics from multiple stakeholder perspectives, as well as the role our specialty may play in helping to shape the future of AI within the larger spectrum of medicine.



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Identification of surgical site infections using electronic health record data

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Publication date: Available online 12 June 2018
Source:American Journal of Infection Control
Author(s): Kathryn L. Colborn, Michael Bronsert, Elise Amioka, Karl Hammermeister, William G. Henderson, Robert Meguid
BackgroundThe objective of this study was to develop an algorithm for identifying surgical site infections (SSIs) using independent variables from electronic health record data and outcomes from the American College of Surgeons National Surgical Quality Improvement Program to supplement manual chart review.MethodsWe fit 3 models to data from patients undergoing operations at the University of Colorado Hospital between 2013 and 2015: a similar model reported previously in the literature, a comprehensive model with 136 possible predictors, and a combination of those. All models used a generalized linear model with a lasso penalty. Several techniques for handling imbalance in the outcome were also used: Youden's J statistic to optimize the probability cutoff and sampling techniques combined with Youden's J. The models were then tested on data from patients undergoing operations during 2016.ResultsTwo hundred thirty of 6,840 patients (3.4%) had an SSI. The comprehensive model fit to the full set of training data performed the best, achieving 90% specificity, 80% sensitivity, and an area under the receiver operating characteristic curve of 0.89.ConclusionsWe identified a model that accurately identified SSIs. The framework presented can be easily implemented by other American College of Surgeons National Surgical Quality Improvement Program-participating hospitals to develop models for enhancing surveillance of SSIs.



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High-risk Staphylococcus aureus transmission in the operating room: A call for widespread improvements in perioperative hand hygiene and patient decolonization practices

Publication date: Available online 12 June 2018
Source:American Journal of Infection Control
Author(s): Randy W. Loftus, Franklin Dexter, Alysha D.M. Robinson
BackgroundIncreased awareness of the epidemiology of transmission of pathogenic bacterial strain characteristics may help to improve compliance with intraoperative infection control measures. Our aim was to characterize the epidemiology of intraoperative transmission of high-risk Staphylococcus aureus sequence types (STs).MethodsS aureus isolates collected from 3 academic medical centers underwent whole cell genome analysis, analytical profile indexing, and biofilm absorbance. Transmission dynamics for hypertransmissible, strong biofilm-forming, antibiotic-resistant, and virulent STs were assessed.ResultsS aureus ST 5 was associated with increased risk of transmission (adjusted incidence risk ratio, 6.67; 95% confidence interval [CI], 1.82-24.41; P = .0008), greater biofilm absorbance (ST 5 median absorbance ± SD, 3.08 ± 0.642 vs other ST median absorbance ± SD, 2.38 ± 1.01; corrected P = .021), multidrug resistance (odds ratio, 7.82; 95% CI, 2.19-27.95; P = .002), and infection (6/38 ST 5 vs 6/140 STs; relative risk, 3.68; 95% CI, 1.26-10.78; P = .022). Provider hands (n = 3) and patients (n = 4) were confirmed sources of ST 5 transmission. Transmission locations included provider hands (n = 3), patient skin sites (n = 4), and environmental surfaces (n = 2). All observed transmission stories involved the within-case mode of transmission. Two of the ST 5 transmission events were directly linked to infection.ConclusionsIntraoperative S aureus ST 5 isolates are hypertransmissible and pathogenic. Improved compliance with hand hygiene and patient decolonization may help to control the spread of these dangerous pathogens.



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The relationship between physical activity, appetite and energy intake in older adults: A systematic review

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Publication date: 1 September 2018
Source:Appetite, Volume 128
Author(s): M.E. Clegg, A. Godfrey
Ageing often causes a reduction in appetite and energy intake in older adults which can result in malnutrition. Current guidelines for older adults suggest increasing physical activity to enhance appetite. However, it is unclear if there is evidence to support this advice. This aim of this review is to assess if appetite and energy intake is changed in older adults that undertake acute or regular physical activity (measured from cross sectional and intervention studies). Databases SPORTDiscus, CINAHL, MEDLINE were searched for studies between 1970 and 2017 using search terms related to ageing, physical activity (including exercise), energy and appetite. Studies included contained adults over 60 years, including acute, cross-sectional and intervention (longitudinal) studies. Of 34 full-text articles assessed, 8 were included. The Cochrane Collaboration's tool was used for assessing risk of bias. No acute studies were found. Of the cross-sectional studies, one study suggested that individuals who undertake habitual physical activity had an increased energy intake and none of the studies found differences in appetite ratings. Energy intakes increased in the intervention studies, though not always sufficiently to maintain energy balance. One study showed that ability to correctly compensate for previous energy intake was better in those that undertake habitual physical activity. The limited number of studies, wide range of data collection methodologies, time-scales and interventions mean that definitive outcomes are difficult to identify. At this stage advice to increase acute or habitual physical activity as a mean to increase appetite is not supported by sufficient evidence.



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Measuring the meat paradox: How ambivalence towards meat influences moral disengagement

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Publication date: 1 September 2018
Source:Appetite, Volume 128
Author(s): Benjamin Buttlar, Eva Walther
Meat consumption elicits highly ambivalent feelings. On the one hand, it is associated with sensory pleasure and tradition; on the other hand, it is linked to moral, ecological, and health-related issues. This conflict is referred to as the meat paradox and it is hypothesized that people who experience the meat paradox resolve resulting discomfort by moral disengagement. However, ambivalence—a central process variable underlying the meat paradox—has never been measured directly, and theorizing on the meat paradox, so far, remains rather elusive. In the present investigation, we assessed meat-related ambivalence by tracking mouse trajectories of people who evaluated meat and plant-based dishes. By using this behavioral measure, our findings support the assumption that omnivores experience greater meat-related ambivalence and use moral disengagement strategies more frequently than non-omnivores. Importantly, our findings also show that experiencing meat-related ambivalence has far-reaching consequences: the larger behavioral ambivalence in omnivores, the higher the use of moral disengagement strategies. Thereby, our findings indicate the importance of ambivalence as a central process variable underlying the meat paradox and highlight how process-orientated research may contribute to our understanding of dietary practices and other potentially harmful behaviors.



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Scholar : These new articles for African Security Review are available online

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Original Articles

Unsolved murders and the investigative failures of the Nigerian police force: Security and sociopolitical implications
Richard A. Aborisade
Pages: 1-14 | DOI: 10.1080/10246029.2017.1294087


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Original Articles

Modeling confrontation naming and discourse informativeness using structural equation modeling
Gerasimos Fergadiotis, Maria Kapantzoglou, Stephen Kintz & Heather Harris Wright
Pages: 1-17 | DOI: 10.1080/02687038.2018.1482404


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A systematic validation of the Empathic Handover approach guided by five factors that foster empathy in design
Wina Smeenk, Janienke Sturm, Jaques Terken & Berry Eggen
Pages: 1-21 | DOI: 10.1080/15710882.2018.1484490


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From the Forthcoming Special Issue: Advances in Aquatic Insect Systematics and Biodiversity in the Neotropics

Platyparnus, a new genus of Dryopidae from the Guiana Shield (Coleoptera: Byrrhoidea, Dryopidae)
William D. Shepard & Cheryl B. Barr
Pages: 1-18 | DOI: 10.1080/01650424.2018.1450987


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New observations regarding Helicobacter pylori and gastric cancer in Mongolia

Helicobacter, EarlyView.


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Socio-economic factors influencing farmers’ willingness to undertake environmental responsibility

Abstract

Acknowledging the importance of water resources protection and sustainable management, the European Parliament enacted directives based on the "polluter-pays" principle aiming for "environmental damage" protection and restoration of water resources. The main aim of this paper is to examine, for the first time in Greece, the possibility of achieving environmental goals, such as reduction of agrochemical pollution and irrigation water use, alongside with the farmers' willingness to undertake the environmental costs arising from their activity. In a questionnaire survey, conducted using a "state preference" method, participants were asked to respond on whether they are willing to absorb an "environmental charge" for the protection and restoration of surface and ground water. It is an essential precondition to understand the factors that affect taxpayers' willingness to participate in the Water Framework Directive, as they are expected to cover the cost of its implementation. The identification of the driving forces that affect stakeholders' environmental decisions can emerge as an important and useful tool in extending public participation in the Water Framework Directive.



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