Scholar : The American Journal of Family Therapy, Volume 46, Issue 2, March-April 2018 is now available online on Taylor & Francis Online

The online platform for Taylor & Francis Online content The American Journal of Family Therapy, Volume 46, Issue 2, March-April 2018 is now available online on Taylor & Francis Online. This new issue contains the following articles: Articles Understanding Infidelity: How Perceptions of Infidelity Behaviors Vary by Sex and One's Own Infidelity Experiences Nathaly Moreno & Emily Pearl Kahumoku-Fessler Pages: 107-121 | DOI: 10.1080/01926187.2018.1441760 Post-Adoption Services for High-Risk Families and Their Children: Preliminary Results of a State-Wide Intervention Raymond V. Burke, The Prevention Group Research Team, Cortney Schlueter, Erin Bader & Karen J. Authier Pages: 122-138 | DOI: 10.1080/01926187.2018.1450687 Neuroticism and Close Relationships: How Negative Affect is Linked with Relationship Disaffection in Couples Irum Saeed Abbasi, Neelam Rattan, Tehmina Kousar & Fatma Khalifa Elsayed Pages: 139-152 | DOI: 10.1080/01926187.2018.1461030 Trauma and Health Symptoms in a Community Sample: Examining the Influences of Gender and Daily Stress Kristin E. Silver, Meera Kumari, Danette Conklin & Gunnur Karakurt Pages: 153-167 | DOI: 10.1080/01926187.2018.1461031 The Role of Attachment Anxiety and Avoidance in Communication Modality and Relationship Quality of Romantic Relationships Initiated Online Eric T. Goodcase, David P. Nalbone, Lorna L. Hecker & Christopher Latty Pages: 168-183 | DOI: 10.1080/01926187.2018.1461032 Feasibility of Biological Sample Collection among a High-Risk Maternal Population for Child Maltreatment-Qualitative Pilot Findings Ashwini Tiwari & Shannon Self-Brown Pages: 184-194 | DOI: 10.1080/01926187.2018.1461033 Goal Effectiveness and Family Functioning Phillip Klever Pages: 195-212 | DOI: 10.1080/01926187.2018.1461581 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Journal of Architectural Conservation are available online

The online platform for Taylor & Francis Online content New for Journal of Architectural Conservation and online now on Taylor & Francis Online: Original Articles Life cycle assessment and historic buildings: energy-efficiency refurbishment versus new construction in Norway | Fredrik Berg & Mie Fuglseth Pages: 1-16 | DOI: 10.1080/13556207.2018.1493664 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Latin American Business Review are available online

The online platform for Taylor & Francis Online content New for Latin American Business Review and online now on Taylor & Francis Online: Errata Erratum Pages: 1-1 | DOI: 10.1080/10978526.2018.1483132 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Activities, Adaptation & Aging are available online

The online platform for Taylor & Francis Online content New for Activities, Adaptation & Aging and online now on Taylor & Francis Online: Original Articles Effects of Exercise Interventions in Older Adults with Various Types of Dementia: Systematic Review Juyoung Park & Iris Cohen Pages: 1-35 | DOI: 10.1080/01924788.2018.1493897 Adaptation to Loss of Visual Function: Implications for Rehabilitation on Subtle Nuances of Communication Patrick Emeka Okonji, Catherine Bailey, Monique Lhussier & Mima Cattan Pages: 1-17 | DOI: 10.1080/01924788.2018.1500056 Older Adults' Perspectives on Volunteering in an Activity-Based Social Program for People with Dementia Areum Han, Diane Brown & Amber Richardson Pages: 1-19 | DOI: 10.1080/01924788.2018.1500055 FREE ACCESS: Health Care for Women International: Research on Women's Health in Africa: Issues, Challenges & Opportunities To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Treatment of synthetic dye baths by Fenton processes: evaluation of their environmental footprint through life cycle assessment

Abstract

Inorganic and organic constituents present in textile effluents have a noticeable effect on the performance of Fenton processes. However, studies have been focused on simple wastewater matrices that do not offer enough information to stakeholders to evaluate their real potential in large-scale facilities. Chemical auxiliaries, commonly present in textile wastewaters (NaCl = 30 g/L, Na₂CO₃ = 5 g/L, and CH₃COONa = 1 g/L), affect both the economic and environmental performance of the process because they increase the treatment time (from 0.5 to 24 h) and the consumption of H₂SO₄ (657%) and NaOH (148%) during conditioning steps. The life cycle assessment (LCA) performed with the IPCC-2013 method revealed that dyeing auxiliaries increase from 1.06 to 3.73 (252%) the emissions of carbon dioxide equivalent (CO₂-Eqv/m³). Electricity consumption can be considered an environmental hotspot because it represents 60% of the carbon footprint of the Fenton process. Also, the presence of auxiliaries is critical for the process because it results in the increase of the relative impact (between 50 and 80%) in all environmental categories considered by the ReCiPe-2008 method. Chemical auxiliaries increased the costs of the treatment process in 178% (US$2.22/m³) due to the higher energy consumption and the additional reagent requirements. It is worthwhile mentioning that the technical simplicity of the Fenton process and its low economic and environmental costs turn this process into an attractive alternative for the treatment of textile effluents in emerging economies.

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Measuring herpes zoster disease burden in São Paulo, Brazil: a clinico-epidemiological single-center study

OBJECTIVES: Herpes zoster is characterized by acute neuritis and post-herpetic neuralgia. Currently, data concerning the zoster-associated impact on quality of life and healthcare resource utilization in Brazil are scarce. This study measured the zoster-associated burden in a Brazilian population. METHODS: This was a prospective, observational, single-cohort study conducted in a primary hospital's emergency room in São Paulo, Brazil. Patients enrolled at various timepoints during a zoster episode were followed over 180 days. The Zoster Brief Pain Inventory and the Initial Zoster Impact Questionnaire assessed zoster-associated pain. The EuroQoL assessed the impact of herpes zoster and/or zoster-associated pain on quality of life. Healthcare resource utilization was assessed by patient-reported questionnaires. RESULTS: One-hundred forty-six zoster patients were enrolled [mean (SD) age of 69.9 (10.9) years]. Mean (SD) worst pain scores decreased from 5.3 (3.5) at baseline to 1.9 (3.0) 180 days following rash onset. Mean (SD) EuroQoL scores significantly decreased from 0.9 (0.2) before rash appearance to 0.7 (0.2) after rash onset (p<0.001), followed by gradual improvements in quality of life over 180 days, with pre-herpes zoster quality of life achieved at the end of the observation period. The majority of patients purchased prescription medications (89.7%) and required doctor's office visits (65.8%) for zoster episodes. CONCLUSIONS: Herpes zoster is associated with a significant disease burden, including zoster-associated pain, impaired quality of life and increased healthcare resource utilization in Brazil. These results support the implementation of early intervention and prevention programs such as vaccinations to reduce the herpes zoster-associated disease burden in Brazil.

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Clinical Application of Atlantoaxial Pedicle Screw Placement Assisted by a Modified 3D-Printed Navigation Template

OBJECTIVES: To investigate the primary clinical value of atlantoaxial pedicle screw placement assisted by a modified 3D-printed navigation template. METHODS: We retrospectively analyzed the cases of 17 patients treated from June 2015 to September 2016 with atlantoaxial pedicle screw placement assisted by a modified 3D-printed navigation template. All procedures were performed prior to surgery, including thin-slice CT scanning, medical image sampling and computerized 3D modeling of the atlantoaxial joint, optimal pedicle screw trajectory determination, and anatomical trait acquisition for the atlantoaxial pedicle, spinous process of the axis, vertebral lamina and posterior lateral mass, and design of a reverse template. During surgery, a navigation template was tightly attached to the atlantoaxial joint to assist in pedicle screw placement. Surgeons subsequently used an electric drill to remove the template through a guide channel and then placed the atlantoaxial pedicle screw. Observed indexes included the VAS score, JOA improvement rate, surgery duration, and blood loss. RESULTS: Surgery was successful in all 17 patients, with an average operation duration of 106±25 min and an average blood loss of 220±125 ml. Three days postoperatively, the VAS score decreased from 6.42±2.21 to 3.15±1.26. Six months postoperatively, the score decreased to 2.05±1.56. The postoperative JOA score increased significantly from 7.68±2.51 to 11.65±2.72 3 d after surgery and to 13.65±2.57 after 6 months. Sixty-eight pedicle screws were inserted successfully, with 34 in the atlas and 34 in the axis. According to the Kawaguchi standard, 66 screws were in grade 0 (97.06%), and 2 were in grade 1 (2.94%). The pre- and postoperative transverse and sagittal screw angles showed no significant differences. CONCLUSIONS: Atlantoaxial pedicle screw placement assisted by a modified 3D-printed navigation template is worth recommending due to the improved accuracy in screw placement, improved patient safety and beneficial clinical effects.

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Scholar : These new articles for Critical Discourse Studies are available online

The online platform for Taylor & Francis Online content New for Critical Discourse Studies and online now on Taylor & Francis Online: Original Articles Religious solidarity, historical mission and moral superiority: construction of external and internal 'others' in AKP's discourses on Syrian refugees in Turkey Rabia Karakaya Polat Pages: 1-17 | DOI: 10.1080/17405904.2018.1500925 To update which email alerts you receive, manage your alerts within the My Account area. Unsubscribe from new content alerts for this journal (both new issue and latest article notifications) with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays—Reply

In Reply We thank Oxnard and Paweletz for their comments on our article. Kuderer et al demonstrated similar discrepancies comparing Guardant360 with tumor tissue, being more frequent at low variant allele fractions (VAFs). However, we disagree that including VAFs "would allow the reader to fully understand the data" because it could only partially explain the discrepancies, and its inclusion would be only mildly informative because it would be necessary to reanalyze the DNA to determine the true nature of these discrepancies with the caveat that other major factors such as timing and processing methods would not be considered.

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Analytical Validity and Clinical Utility of Tumor Biomarkers

To the Editor In his recent editorial, Dr Hayes correctly noted that "analytical validity and clinical utility" are needed for the adoption of a tumor biomarker test into clinical care. However, proving analytical validity with correlative or concordance studies is largely irrelevant without first proving clinical utility.

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A New Dark Skin Lesion in a 3-Year-Old Undergoing Acute Lymphoblastic Leukemia Induction Therapy

A 3-year-old girl with B-cell acute lymphoblastic leukemia and no known skin trauma presented with an asymptomatic skin lesion with violaceous to black plaque, a central hemorrhagic bulla, and surrounding hyperemia on the left lower back. What is your diagnosis?

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Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays

To the Editor We read with interest the article by Torga and Pienta. They address a timely and important subject, not just for liquid biopsies but also for other commercial next-generation sequencing offerings, and delve deeper into the need for rigorous analytical validation of assays that are used widely in patient care. Unfortunately, there are some key pieces of information missing to allow the reader to fully understand the data. The authors do not provide the variant type or allele frequencies (AFs) for called variants, which is important given different reporting criteria for different assays. Moreover, Stetson et al showed in a similar comparison much greater concordance for variants called at greater than 1% AFs, but striking variability with AFs of less than 1%. Having this information would allow for a discussion as to the difficulties in interpreting plasma next-generation sequencing with low AF results. The study by Torga and Pienta does succeed in cautioning the reader that not all laboratory-developed tests are created equal, and points to a need for rigorously validated reference materials for all assays to benchmark against in the pursuit of more consistent reporting of these important clinical results.

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Complementary Medicine, Refusal of Cancer Therapy, and Survival Among Patients With Curable Cancers

This cohort study compares overall survival, treatment adherence, and patient characteristics among patients with cancer receiving conventional cancer treatment with vs without complementary medicine.

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Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays

To the Editor Torga and Pienta reported low congruence between 2 circulating tumor DNA sequencing assays in 40 patients with metastatic prostate cancer. However, the mutant allele fraction (MAF) of reported genomic alterations, which may help clarify the cause of low congruence, is unmentioned in their report. Other than analytical factors, sampling error may affect the replicability of the circulating tumor DNA testing result when genomic alterations with low MAF are encountered. Five to 30 ng (ie, 1500-9000 genome equivalents) of cell-free DNA was used as input material in the Guardant360 assay. For example, for an alteration with an MAF of 0.1% and a cell-free DNA sample of 5 ng (ie, 1500 genome equivalents), the possibility that no single copy of the DNA molecule of the alteration is present in the sample is 22.3% (possibility that the DNA molecule of the alteration is not present in a given genome equivalent = 1 − 0.001 = 0.999; possibility that the DNA molecule of the alteration is not present in all 1500 genome equivalents = 0.999¹⁵⁰⁰ ≈ 0.223). In other words, 22.3% of testing results of the alteration are negative simply due to chance. Therefore, the possibility of congruence between 2 assays for this alteration is as low as 65.4% (possibility of negative results in both assays ≈ 0.223 × 0.223 ≈ 0.050; possibility of positive results in both assays ≈ 0.777 × 0.777 ≈ 0.604; possibility of congruence ≈ 0.050 + 0.604 = 0.654). Furthermore, the congruence may be even lower if analytical factors are considered. Thus, MAF data may provide insights into the root cause of low congruence between these 2 assays.

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Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays

To the Editor The recent analysis by Torga and Pienta attempted to evaluate 2 liquid biopsy test platforms (Guardant360 and PlasmaSELECT) and found "low congruence for the same patient-paired samples." However, having reanalyzed their available data, we conclude that the authors inappropriately performed a qualitative comparison of 2 quantitative tests with different reporting standards, resulting in a misrepresentation of the underlying data and misleading conclusions. Correcting for these issues, we instead find 91% patient-level concordance between the 2 tests and 100% concordance for results associated with indicated therapies.

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Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays

To the Editor The recent Research Letter comparing 2 cell-free DNA next-generation sequencing tests in prostate cancer has severe methodological flaws. It improperly confuses clinicians and implies that laboratory accreditation standards are lax. Published cell-free DNA test concordance study design criteria include:

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Monthly High-Dose Vitamin D Supplementation and Cancer Risk

This post hoc analysis of the Vitamin D Assessment randomized clinical trial assesses the association of monthly high-dose vitamin D supplementation vs placebo on cancer risk among New Zealand adults.

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Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays

To the Editor The blood-diagnostics field has evolved in the past decade, realizing the ability to detect driver mutations and resistance clones, allowing the application of targeted therapies and the concept of molecular selection and therapeutic monitoring using "liquid biopsy." Recently in JAMA Oncology, Torga and Pienta reported divergent results between 40 patient-paired blood samples in advanced prostate cancer using 2 commercially available cell-free circulating tumor DNA (ctDNA) tests (Guardant360 and PlasmaSelect). The results indicated low congruence between the 2 tests, and the authors concluded that the data were concerning with regard to standard clinical use of ctDNA.

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Transforming Growth Factor β Polymorphism C−509T and Radiation-Induced Fibrosis in Breast Cancer

This cohort study of female participants with stage 0 to IIA breast cancer treated with breast-conserving surgery and whole-breast irradiation assesses whether radiation-induced toxicities of normal breast tissue 3 years after radiotherapy are associated with the transforming growth factor β gene variant C−509T.

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Ethical Implications of Direct-to-Consumer Hereditary Cancer Tests

This Viewpoint examines the ethics of informed consent and test result disclosure associated with direct-to-consumer genetic testing for hereditary cancer susceptibility.

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