A crucial role of L-selectin in C protein-induced experimental polymyositis of mice

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Kyosuke Oishi, Yasuhito Hamaguchi, Takashi Matsushita, Minoru Hasegawa, Naoko Okiyama, Jens Dernedde, Marie Weinhart, Rainer Haag, Thomas F. Tedder, Kazuhiko Takehara, Hitoshi Kosaka, Manabu Fujimoto




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Decreased IL-20 expression in scleroderma skin contributes to cutaneous fibrosis

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Hideo Kudo, Masatoshi Jinnin, Hironobu Ihn




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Possible mechanisms of epicutaneous-sensitized anaphylactic reaction in the mouse model

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Rie Yu, Ken Igawa, Takichi Munetsugu, Takahiro Satoh, Hiroo Yokozeki




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Cav eolin-1 reduction induced by psoriasis-related cytokines enhances psoriatic pathogenic inflammation

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Yukie Yamaguchi, Yuko Watanabe, Noriko Koumitsu, Tomoya Watanabe, Michiko Aihara




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Prostaglandin E2-EP2 signaling in keratinocytes is an endogenous regulator for Th2 skin immunity by down-regulating PAR2 expression

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Tetsuya Honda, Yu Sawada, Yoshiki Miyachi, Kenji Kabashima




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Identification of disease-specific molecules in the skin of dermatomyositis and lupus erythematosus by proteomics analysis using LC–MS/MS

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Kayo Nakamura, Masatoshi Jinnin, Satoshi Fukushima, Hironobu Ihn




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Requirement of aquaporin-3-mediated hydrogen peroxide for NF-κB cell signaling and psoriasis pathogenesis

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Mariko Hara-Chikuma, Hiroki Satooka




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Expression of Mas-related gene X2 on skin mast cells is upregulated in the patients with severe chronic spontaneous urticaria

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Koremasa Hayama, Daisuke Fujisawa, Jun-ichi Kashiwakura, Hirohito Kita, Yusuke Kikukawa, Yashushi Fujitani, Tomomi Sasaki-sakamoto, Kazumichi Kuroda, Satoshi Nunomura, Chisei Ra, Yoshimichi Okayama, Tadashi Terui




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Role of mast cells in the development and maintenance of lupus-like skin lesions on MRL-lpr/lpr mice

Publication date: October 2016
Source:Journal of Dermatological Science, Volume 84, Issue 1
Author(s): Yutaka Inaba, Takashi Yoshimasu, Nobuo Kanazawa, Fukumi Furukawa




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Reporting of Malposition of Lines and Tubes on Portable Radiographs using Alert Notification of Critical Results

Publication date: Available online 28 September 2016
Source:Current Problems in Diagnostic Radiology
Author(s): Rachna Madan, LaTia D. Peavy, Breland Crudup, Andetta Hunsaker
Line malposition may result in significant iatrogenic complications. Awareness of the most common types of line malposition and the frequency of significant line related complications is an important reminder to the radiologist to look carefully at all lines, especially the devices that are most commonly subject to malposition. Alert Notification of Critical Results (ANCR) are computer-generated pages or emails created by the radiologist to inform referring clinicians of significant radiologic findings. The alert is logged on the computer and all data is saved for future review. The primary purpose of the ANCR is to ensure that radiologists and clinicians have an effective and well-documented method of communication regarding significant imaging findings. A secondary purpose of ANCR data is the ability to review clinical practice. We have used the ANCR data to identify the frequency and types of line malpositions in the ICU.



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Scholar : These new articles for Annals of the American Association of Geographers are available online

The online platform for Taylor & Francis Online content New for Annals of the American Association of Geographers and online now on Taylor & Francis Online: Methods, Models, and GIS Using Geonarratives to Explore the Diverse Temporalities of Therapeutic Landscapes: Perspectives from "Green" and "Blue" Settings Sarah L. Bell, Benedict W. Wheeler & Cassandra Phoenix Pages: 1-16 | DOI: 10.1080/24694452.2016.1218269 People, Place, and Region Children, Critical Geopolitics, and Peace: Mapping and Mobilizing Children's Hopes for Peace in the Philippines Chih Yuan Woon Pages: 1-18 | DOI: 10.1080/24694452.2016.1218268 Environmental Sciences Relations of Alpine Plant Communities across Environmental Gradients: Multilevel versus Multiscale Analyses George P. Malanson, Dale L. Zimmerman, Mitch Kinney & Daniel B. Fagre Pages: 1-13 | DOI: 10.1080/24694452.2016.1218267 Selling Ethics: Discourses of Responsibility in Tourism Harng Luh Sin Pages: 1-17 | DOI: 10.1080/24694452.2016.1218266 Have you seen the SRHE's new journal? Policy Reviews in Higher Education is now looking for submissions, click here to find out more and submit your paper. This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Amyloid are available online

The online platform for Taylor & Francis Online content New for Amyloid and online now on Taylor & Francis Online: Original Article Capillary electrophoresis/immunosubtraction as a better alternative to immunofixation for detecting and immunotyping serum monoclonal proteins in patients with immunoglobulin light chain (AL) amyloidosis Kanji Miyazaki & Kenshi Suzuki Pages: 1-4 | DOI: 10.1080/13506129.2016.1232647 eHealth and mHealth Free Access Article Collection – click here This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Acute Cardiac Care are available online

The online platform for Taylor & Francis Online content New for Acute Cardiac Care and online now on Taylor & Francis Online: ORIGINAL ARTICLE Intrathecal baclofen withdrawal: A rare cause of reversible cardiomyopathy* Stephen O. Awuor, Paul M. Kitei, Yassir Nawaz & Amy M. Ahnert Pages: 1-5 | DOI: 10.3109/17482941.2016.1174273 World Cancer Day Free Access Article Collection - click here. This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Hospitalisations with Hidradenitis Suppurativa: An Increasing Problem That Deserves Closer Attention

Background/Aims: Hidradenitis suppurativa (HS), a chronic inflammatory skin disease of the hair follicle, can lead to scarring and disability. With an estimated European prevalence of 1%, few epidemiological studies of HS have been performed, and none focused on hospitalisations. We aimed to study the time trends of HS hospitalisations and to evaluate the demographic characteristics, hospital incidence rate, readmissions, length of stay, comorbidities and risk factors of hospitalised HS patients. Methods: We performed a retrospective observational study using a national administrative database in Portugal, with discharges between 2000 and 2014. All the inpatients aged 5 years or more with a diagnosis of HS were included. Variables analysed were age, sex, admission and discharge date, discharge outcome and diagnoses. Results: A total of 1,177 patients were hospitalised in this time period (48 were aged 18 years or younger) with a male-to-female ratio of 1:1.17. There was a hospital incidence rate of 0.83 patients with HS per 100,000 person-years (95% CI = 0.78-0.88). The age group with the highest incidence rate was 20-29 years among women and 40-49 years among men. We recorded an increasing trend in the number of new hospitalised patients and in the hospital incidence rate of HS. Tobacco was the most common comorbidity/risk factor. Eighty-three percent of our population underwent HS surgery. Conclusion: This hospital-based incidence study showed that admission for HS is increasing and that the majority of the HS inpatients were surgical cases. In the future, prospective studies will be important to assess risk factors for hospitalisations and complications.
Dermatology

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Scholar : These new articles for Asian Englishes are available online

The online platform for Taylor & Francis Online content New for Asian Englishes and online now on Taylor & Francis Online: Book Review English in Malaysia Debbie G.E. Ho Pages: 1-3 | DOI: 10.1080/13488678.2016.1226399 Teaching and assessing EIL in local contexts around the world Mariko Takahashi Pages: 1-3 | DOI: 10.1080/13488678.2016.1226400 Have you discovered Lives in Literature yet? Free access to research on some of Literature's most notable names;new collections will be added regularly so bookmark the page and visit again! This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Archives and Records are available online

The online platform for Taylor & Francis Online content New for Archives and Records and online now on Taylor & Francis Online: Opinion Role of public archivists in post-apartheid South Africa: passive custodians or proactive narrators Isabel Schellnack-Kelly Pages: 1-23 | DOI: 10.1080/23257962.2016.1214560 Time and tide wait for no man (or woman). Explore the multidisciplinary TIME Collection now. This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Atmosphere-Ocean are available online

The online platform for Taylor & Francis Online content New for Atmosphere-Ocean and online now on Taylor & Francis Online: Original Articles Upper-Level Winds over Southern Ontario: O-QNet Wind Profiler and NARR Comparisons Peter A. Taylor, Wensong Weng, Zheng Qi Wang, Mathew Corkum, Khalid Malik, Shama Sharma & Wayne Hocking Pages: 1-11 | DOI: 10.1080/07055900.2016.1231658 Evaluation of Total Precipitable Water from CRCM4 using the NVAP-MEaSUREs Dataset and ERA-Interim Reanalysis Data | D. Paquin, A. Frigon & K. E. Kunkel Pages: 1-8 | DOI: 10.1080/07055900.2016.1230043 Time and tide wait for no man (or woman). Explore the multidisciplinary TIME Collection now. This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Dramatherapy are available online

The online platform for Taylor & Francis Online content New for Dramatherapy and online now on Taylor & Francis Online: Article Dramatherapy – the French way Sandrine Pitarque Pages: 1-14 | DOI: 10.1080/02630672.2016.1217698 Routledge Psychoanalysis Like the Facebook Page for the latest Psychoanalysis news and offers. This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for African Security are available online

The online platform for Taylor & Francis Online content New for African Security and online now on Taylor & Francis Online: Original Articles Food (in)security, human (in)security, women's (in)security: State policies and local experiences in rural Rwanda Marie Jeanne Nzayisenga, Camilla Orjuela & Isabell Schierenbeck This is the author accepted version which has not been proofed or edited Passionate about Social Media? Read our Social Media Research collection. This message is personalised to your status as a society member. Please do not forward this email. To recommend content, please use the social sharing tools on the website. To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

10-year follow-up study comparing primary medical vs. surgical therapy in women with prolactinomas

Abstract

While dopamine-agonists are the first-line approach in treating prolactinomas, surgery can be considered in selected cases besides non-responders or patients with dopamine-agonist intolerance. The aim of the present study was to compare the long-term outcome in women with prolactinomas treated primarily either surgically or medically who had not had prior dopamine-agonist treatment. Retrospective case-note study of all consecutive women with prolactinomas primarily managed with medical therapy or surgery in a tertiary referral centre. The clinical, biochemical, and radiological responses to first-line treatment at early and long-term follow-up were analysed. The primary therapeutic strategy was dopamine-agonists for 36 (34 %) and surgery for 71 (66 %) of the women. Baseline clinical and biochemical characteristics were not significantly different between the primary surgical and medical cohort. Median follow-up time was 90 months (range 13–408). Following primary treatment, prolactin level significantly decreased in both cohorts, on average to 13.5 µg/L (IQR 7–21; p < 0.001), and was within the normal range in 82 % of all patients. No women in the surgical cohort demonstrated permanent sequelae and morbidity was low. At final follow-up, control of hyperprolactinaemia required dopamine-agonist therapy in 64 % of women who had undergone primary medical therapy vs. 32 % of those who had primary surgical therapy (p = 0.003). Logistic regression revealed that the primary therapeutic strategy, but not adenoma size, was an independent risk factor for long-term dependence on dopamine-agonists. The present data indicate that in a dedicated tertiary referral centre, long-term control of hyperprolactinaemia in women with prolactinomas is high. In selected cases, a primary neurosurgical approach might at least be interdisciplinarily discussed with the primary goal of minimizing long-term dependence on dopamine-agonists.

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