Intrinsically Disordered Proteins Adaptively Reorganize Cellular Matter During Stress

Publication date: Available online 6 May 2017
Source:Trends in Biochemical Sciences
Author(s): Sreenivas Chavali, Alexander Gunnarsson, M. Madan Babu
Intrinsically disordered proteins (IDPs) can protect cells from diverse stresses by forming higher order assemblies such as reversible aggregates or granules. Recently, Boothby et al. show that IDPs protect tardigrades against desiccation by forming a glass-like amorphous matrix, highlighting that material properties of disordered proteins can confer adaptation during stress.



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Scholar : Ειδοποίηση Μελετητή - [ CPAP ]

Ειδοποίηση Μελετητή:[ CPAP ]

Therapeutic Cpap Level Predicts Upper Airway Collapsibility In Patients With Obstructive Sleep Apnea

SA Joosten, DJ Eckert, A Jordan, SA Sands, DP White… - Am J Respir Crit Care Med, 2017

Rationale: patients with mild upper airway collapsibility (compared to highly collapsible
airways) at baseline are more likely to respond to non-CPAP treatment for OSA, such as
weight loss, oral appliance therapy, as well a non-anatomical interventions, such as the

The Effect Of Extended Continuous Positive Airway Pressure (cpap) On Lung Volumes In Stable Premature Infants: A Randomized Controlled Trial

D Schilling, B Scottoline, A Platteau, M Niederhausen… - Am J Respir Crit Care Med, 2017

Rationale no consensus regarding the optimal criteria to discontinue CPAP in stable
premature infants. Animal models have shown improved lung growth after CPAP (J Appl
Physiol 1996; 81: 1471-76). We hypothesized that premature infants meeting stability criteria

Impact Of Automatic Positive Airway Pressure On Treatment Compliance In Obstructive Sleep Apnea Patients Awaiting Bariatric Surgery

CAC APAP - Am J Respir Crit Care Med, 2017

RESULTS The recruitement is stil ongoing and 46 subjects are currently enrolled. Overall,
the two groups do not differ in age, gender and baseline medical conditions. Data were
collected after 1 month use of therapy and at the elective admission for bariatric surgery,

Prevalence Of Sleep Disordered Breathing In Patients With Cardiovascular Disease: Registry To Examine The Effect Of Cpap On Cardiac Function In Hospitalized …

ME Crocker, J Riggs, G Nathanson, LW Kim, L Chi… - Am J Respir Crit Care Med, 2017

Rationale sleep apnea (OSA) than central sleep apnea (CSA); and 2) the effect of
continuous positive airway pressure (CPAP) on cardiac function and readmission rates. The
study involves performing portable sleep studies in hospitalized patients with cardiac

Effects Of cpap On Sleep Quality, Stroke And All Cause Mortality: A Pooled Meta-Analysis Of Randomized Controlled Trials

A Rajabalan, SD Paudel, P Thiruveethy, TS Ahmed… - Am J Respir Crit Care Med, 2017

Methods: Literature search was done from electronic data bases (2010 through September
2016) including Pubmed, Cochrane and Embase to search for relevant studies. Additional
studies were also added from the reference mentioned in the collected studies. Only

Effects Of Cpap On Cardiovascular Outcomes In Patients With Obstructive Sleep Apnea: A Pooled Meta-Analysis Of Randomized Controlled Trials

D Shahi, SD Paudel, P Thiruveethy, TS Ahmed… - Am J Respir Crit Care Med, 2017

/ Mini Symposium / Monday, May 22/2:15 PM-4:15 PM / Room 152 AB (Middle Building, Street
Level) Walter E. ... B98 OSA AND CORONARY ARTERY DISEASE: ARE WE SAVE-ING
LIVES? ... Effects Of Cpap On Cardiovascular Outcomes In Patients With Obstructive Sleep

Continuous Positive Airway Pressure (cpap) Increases Respiratory Rate Variability

S Alrawaf, G Alrehaili, AW McLean, J Williams… - Am J Respir Crit Care Med, 2017

Results Epworth scale 10±6. During the study the optimal titration CPAP was 8±3 cmH O
with 87±7% minimal SpO. There was a mean 2 2 increase in RRV of 24%, 27% and 20%
across all sleep stages for Mild, Moderate and Severe patients, respectively (p< 0.001; Fig

The Effects Of Supplemental Oxygen On Obstructive Sleep Apnea During Cpap Withdrawal: Preliminary Data From A Randomised Control Trial

A Johar, N Petousi, JR Stradling, C Turnbull - Am J Respir Crit Care Med, 2017

Methods Patients with OSA, established on CPAP> 1 year and with> 4 hours/night usage
underwent a week of screening oximetry and were eligible if they had an oxygen
desaturation index≥ 4%(ODI)< 10 on 3 nights on CPAP and an ODI> 20 on 4 nights off

A Randomized Trial Demonstrating The Feasibility Of A Group-Based Peer-Support Intervention For Maximizing Cpap Adherence

M Cailler, N Khan, M Hanson, A Kirkpatrick, KA Dudley… - Am J Respir Crit Care Med, 2017

Methods We performed a 6-week, open-label, parallel-arm, randomized controlled trial
comparing a group-based peer-support intervention with usual care. All participants
underwent a standardized 1-hour CPAP education session with a single staff member. Mask

Effects Of Humidified And Non-Humidified Nasal Cpap On Development Of Nasal Symptoms And Subjects Comfort Level: A Preliminary Study

P Worsley, D Voegeli, JS Alqahtani - Am J Respir Crit Care Med, 2017

Methods A crossover cohort design was used in this study, with 15 healthy volunteers
served as their own controls, randomly receiving both 10 cmH O of CPAP with humidification
and without through an oronasal mask. Upper airway nasal symptoms were collected at

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Scholar : Ειδοποίηση Μελετητή - [ ΜΑΣΤΟ

Ειδοποίηση Μελετητή:[ ΜΑΣΤΟΕΙΔΙΤΙΣ ]

[PDF] Case Report Radiographic findings on inflammatory myofibroblastic tumor of the carotid artery: report of two cases

W Li, L Yang, F Yang, Y Qiao - Int J Clin Exp Med, 2017

... Total serum IgG and IgG4 lev- els were also within normal limits. Apart from
aforementioned symptoms, the patient also suffered from severe hypertension,
bilateral nasal sinusitis, bilateral mastoiditis, anemia, and colitis gravis. ...

Consolidating A Rare Consolidation

D Thomson, R Talento, A Mohan, S Marco - Am J Respir Crit Care Med, 2017

... paraprotein gap. She did not improve with two trials of antibiotics and ultimately was
referred to an otolaryngologist where computed tomography (CT) of her head revealed
mastoiditis leading to planned sinus biopsy. Preceding ...

[HTML] Parents overestimate benefits of antibiotics for acute respiratory infections

B Kronemyer - 2017

... "By taking antibiotics, resistance develops in the bacteria in the individual," he says. "Then, if
that individual becomes ill from a serious infection—mastoiditis, pneumonia meningitis, septicemia,
and so on—this resistance can be transferred to a dangerous pathogen, which may ...

[PDF] Septic Arthritis of the Temporomandibular Joint without an Apparent Source of Infection: A Case Report

D Suda, H Takatsuji, N Saito, A Funayama, K Niimi… - Open Journal of …, 2017

... bacteria [11]. Contiguous spread of infection is common after dental procedures
[6] [11], parotiditis, mastoiditis or otitis [12]. Direct inoculations occur secondarily
to arthrocentesis, arthroscopy or acupuncture [13]. Risk factors ...

[PDF] Effects of Fusobacterium Necrophorum on Pathogenesis and Potential Disease-Associated Factors in Plasma in Cattle with Footrot

J Xiao, D Sun, H Wang - Br Biomed Bull, 2017

... Furthermore, it causes pharyngotonsillitis, pharyngitis, parotitis, dental abscesses, and
middle ear infections, including mastoiditis [44-46]. In cattle, Fusobacterium necrophorum
is classified into two subspecies, ss. necrophorum and ss. ...

[PDF] Functional magnetic resonance imaging evidence in patients with sudden sensorineural hearing loss

H Ren, L Wen, K Chen, X Wu - Int J Clin Exp Med, 2017

... Lacunar infarction 3 Stenosis of the anterior-inferior artery in the cerebellum 2 Sclerosis of the
vertebral artery 2 Unrelated etiology 18 Mastoiditis 4 15% Arachnoid cyst 3 Meningioma of the
tentorium cerebelli 1 Malformation of the blood vessels in the brain 2 Cerebral atrophy 3 ...

[HTML] FarGALS efficiency in complex treatment of HIV-infected children with acute purulent sinusitis

NN Umarovich - European science review, 2017

... At AIDS children may manifest a typical or recurrent diseases ofthe ear, sinuses,
mastoiditis, tonsillitis, pharyngitis, an inflammation of the orbital and periorbital tissue,
oropharyngeal candidos and infectious lesions of teeth [1; 2; 10]. ...

[HTML] Abses Serebri Multipel

AS MULTIPEL, RHA MALIK - Universitas

... dan jarang akibat Pneumococcus, Meningococcus, dan Haemophylus Influenza.1,3,4 Ada 3
mekanisme bahan-bahan infeksius bisa masuk ke otak, yang pertama dengan perluasan
langsung dari infeksi yang berdekatan seperti otitis media, mastoiditis, atau sinusitis paranasal ...

[PDF] Citelli's Abscess Following Otitis Media: A Case Report

A Sahoo, C Preetam, D Samal, S Sarkar

... more common in the squamosal type. A common complication of OM is acute
mastoiditis which can lead to a variety of abscesses (2). Citelli's abscess is an
extratemporal complication of otitis media. It occurs when pus from ...

[PDF] CT and MRI findings in skull base osteomyelitis-A pictorial essay

A Palleti, HC Chadaga, NS Verma, R Hanumaiah

... Results: The clinical characteristics of patients are summarized in Table 1. Headache was the
chief complaint in all of our patients and without evidence of external otitis, acute otitis media,
or mastoiditis. All patients had cranial neuropathy by the time they presented. ...

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