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Τρίτη 30 Μαΐου 2017
Scholar : These new articles for Advances in School Mental Health Promotion are available online
Scholar : These new articles for Archives and Manuscripts are available online
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Enhanced biocompatibility and long-term durability in vivo of Mg-Nd-Zn-Zr alloy for vascular stent application
Publication date: 5 October 2017
Source:Journal of Alloys and Compounds, Volume 720
Author(s): Lin Mao, Hao Zhou, Li Chen, Jialin Niu, Lei Zhang, Guangyin Yuan, Chengli Song
Biodegradable magnesium (Mg) alloy emerges as revolutionary biomaterial by meeting both engineering and medical requirements for implants. In this study, we report a Mg alloy Mg-2.5Nd-0.21Zn-0.44Zr (wt. %, denoted as JDBM) potential for vascular stent application due to its outstanding performance in corrosion behaviors and biocompatibility. The investigation of corrosion properties evaluated by immersion test and electrochemical measurement shows less susceptibility to pitting corrosion and lower corrosion rate of JDBM as compared with AZ31 alloy. The corrosion products of JDBM do not cause significant adverse effect on the cell viability and growth during in vitro cytotoxicity test of the Mg extract via human vascular endothelial cells (HUVECs). We also investigated macrophage response to the Mg extract and observed compromised foreign body reaction (FBR) determined by human peripheral blood derived macrophage fusion and inflammatory cytokine and chemokine secretion. At last, we performed in vivo degradation assessment via implantation of JDBM stent in an animal model, and confirmed long-term stability and structural integrity of the stent in blood vessel. Thus, the JDBM alloy with excellent biocompatibility and long-term stability and durability in vivo, represents a significant advance in the development of biodegradable implants.
http://ift.tt/2qxfr8Q
Experimental study on thermal and chemical stability of pentaerythritol blended with low melting alloy as possible PCM for latent heat storage
Publication date: November 2017
Source:Experimental Thermal and Fluid Science, Volume 88
Author(s): K.P. Venkitaraj, S. Suresh
This paper presents the experimental investigation on the performance of a novel organic Solid-Solid/Low Melting Alloy composite PCM for thermal energy storage applications. Poly alcohols are solid-solid organic PCMs having low heat transfer characteristics due to their poor thermal conductivity. So additives are used to improve the thermal properties of poly alcohols. Metal and its alloys with low melting point exhibit a much stronger heat transfer capacity than that of traditional organic PCMs. Therefore, low melting metals and alloys can be considered as effective additives for improving the thermal performance of organic PCMs. But the presence of additives used for enhancing the heat transfer characteristics may result in thermal and chemical degradation of the material. In this experimental work, the effect of adding the low melting alloy (LMA) of Bi, Sn, Zn and In on the thermal and chemical stability of Pentaerythritol (PE) was investigated using the characterisation methods such as TGA-DTA, DSC and FTIR. For this, thermal cycling of pure PE, and PE mixed with 0.1% & 0.5% of LMA were performed. The characterisation results of PE mixed with LMA after 100 thermal cycles were compared with pure PE samples. The thermal conductivity of the PCM samples was studied using laser flash method. It was found that thermal conductivity of PE, PE+0.1%LMA, and PE+0.5%LMA after 100 thermal cycles decreased by 3.21%, 4.55% and 10.08%. Thermogravimetric analysis of pentaerythritol added with LMA showed a noticeable change in material thermal behavior due to thermal cycling. The test results revealed that the weight loss in the pure PE was lower than the weight loss for PE samples mixed with LMA subjected to 100 thermal cycles. The FTIR results did not show the formation of any new chemical bonds in pentaerythritol and therefore PE samples with LMA additives can be considered as chemically stable during thermal cycling. DSC and DTA results showed about 6%, 8% and 15% of the decrease in enthalpy value after 100 thermal cycles for pure PE, PE+0.1%LMA and PE+0.5%LMA respectively. Thermal storage/release test conducted showed a decrease of 14.64% and 30.22% in the time taken for total energy storage and release for PE+0.1%LMA and PE+0.5%LMA compared to pure PE.
Graphical abstract
http://ift.tt/2rhUmN6
Micro-electrolysis/retinervus luffae-based simultaneous autotrophic and heterotrophic denitrification for low C/N wastewater treatment
Abstract
Nitrogen bioremediation in organic insufficient wastewater generally requires an extra carbon source. In this study, nitrate-contaminated wastewater was treated effectively through simultaneous autotrophic and heterotrophic denitrification based on micro-electrolysis carriers (MECs) and retinervus luffae fructus (RLF), respectively. The average nitrate and total nitrogen removal rates reached 96.3 and 94.0% in the MECs/RLF-based autotrophic and heterotrophic denitrification (MRAHD) system without ammonia and nitrite accumulation. The performance of MRAHD was better than that of MEC-based autotrophic denitrification for the wastewater treatment with low carbon nitrogen (COD/N) ratio. Real-time quantitative polymerase chain reaction (qPCR) revealed that the relative abundance of nirS-type denitrifiers attached to MECs (4.9%) and RLF (5.0%) was similar. Illumina sequencing suggested that the dominant genera were Thiobacillus (7.0%) and Denitratisoma (5.7%), which attached to MECs and RLF, respectively. Sulfuritalea was discovered as the dominant genus in the middle of the reactor. The synergistic interaction between autotrophic and heterotrophic denitrifiers played a vital role in the mixotrophic substrate environment.
http://ift.tt/2qw8Yvc
Efficacy of Mentha pulegium extract in the treatment of functional dyspepsia: a randomized double-blind placebo-controlled clinical trial
Publication date: Available online 30 May 2017
Source:Journal of Ethnopharmacology
Author(s): Ahmad Khonche, Hasan Fallah Huseini, Hamed abdi, Reza Mohtashami, Farzaneh Nabati, Saeed Kianbakht
Ethnopharmacological evidenceMentha pulegium L. leaves are used in the Iranian traditional medicine for the treatment of functional dyspepsia.Aim of studyTo study the efficacy and safety of M. pulegium in the treatment of functional dyspepsia patients fulfilling the Rome III criteria.Materials and methodsIn this study, the efficacy and safety of a standardized Mentha pulegium leaf extract (330mg three times daily taken for 2 months) in the treatment of 50 functional dyspepsia patients were compared with those of the placebo (n = 50).ResultsThe extract significantly decreased the total dyspepsia score measured by the Hong Kong dyspepsia index compared to the placebo and baseline (P = 0.011 and P < 0.001 respectively). The stomach pain, upper abdominal bloating, upper abdominal dull ache, belching and total dyspepsia scores were decreased from baseline in the extract group significantly compared to the placebo (P < 0.001, P < 0.001, P = 0.003, P < 0.001 and P < 0.001 respectively). However, the decreases of other dyspepsia symptoms scores from baseline in the extract group were not significant compared to the placebo (P > 0.05). The extract improved the quality of life measured by the SF-36 questionnaire significantly compared to the placebo and baseline (P = 0.003 and P < 0.001 respectively). Moreover, the extract lowered the rate of H. pylori infection determined by the urease test significantly compared to the placebo and baseline (P = 0.001 and P < 0.001 respectively). The extract did not significantly affect the complete blood count and liver and kidney function tests (P > 0.05). The patients did not experience any adverse drug effect.Conclusions:M. pulegium seems safe and effective in the treatment of functional dyspepsia.
Graphical abstract
http://ift.tt/2r8qjJ7
Renal protective effect and action mechanism of Huangkui capsule and its main five flavonoids
Publication date: 12 July 2017
Source:Journal of Ethnopharmacology, Volume 206
Author(s): Hong-Die Cai, Shu-Lan Su, Da-Wei Qian, Sheng Guo, Wei-Wei Tao, Xu Dong Cong, Renmao Tang, Jin-Ao Duan
Ethnopharmacological relevanceThe flower of Abelmoschus manihot (Linn.) Medicus (A. manihot), as a traditional Chinese Herbal medicine, was used widely in China with efficacy of inducing diuresis for treating strangurtia, and subdhing swelling and detoxicating. It has been reported that Huangkui capsule, prepared by the extract of the flower of A. manihot, can reduce the content of urinary protein, serum creatinine and serum urea nitrogen in nephropathy rats and processes renoprotective activity, while the action mechanism need to illuminate deeply.Aims of the studyIn this study, we investigated the protection effect of Huangkui capsule on tubulointerstitial fibrosis in chronic renal failure (CRF) rats and its mechanism against high glucose-induced epithelial to mesenchymal transition (EMT) in renal tubular epithelial cells (HK-2) of its bioactive components.Materials and methodsThe animals were divided into normal group, CRF model group and Huangkui capsule-treated group. Hematoxylin eosin (HE) staining and Masson staining were applied to observe pathological changes in renal tissue of different groups. Biochemical indicators including serum urea nitrogen (BUN), urine protein (UP) and serum creatinine (Scr) were measured according to the manufacturer's instructions of kits. HK-2 cell damaged model was established to access the protection effect and action mechanism of five main flavonoids from Huangkui capsule. The experimental cells were divided into eight groups: control group, model group, positive drug group and five main flavonoids treated groups. The dichlorodihydrofluorescein diacetate (DCFH-DA) assay was used to determine the reactive oxygen species (ROS) in different groups. Western blot was applied to analyze the expression of pathogenesis-related proteins in different groups.ResultsThe results stated that Huangkui capsule significantly inhibited the elevation of Scr, BUN, UP, the expression of α-smooth muscle actin (α-SMA), phosphorylation-extracellular signal-regulated kinase (p-ERK1/2), NADPH Oxidase 1, NADPH Oxidase 2 and NADPH Oxidase 4 in adenine-induced CRF rats. The main bioactive components of quercetin (QT), hyperoside (HY), isoquercitrin (IQT), gossypetin-8-O-β-D-glucuronide (GG) and quercetin-3′-O-glucoside (QG) at the dosage of 100µM, like NADPH oxidase inhibitor diphenyleneiodonium, exhibited a significant effect on inhibiting the expression of α-SMA, p-ERK1/2, NADPH Oxidase 1, NADPH Oxidase 2 and NADPH Oxidase 4 in high glucose-induced HK-2 cells, especially GG.ConclusionsThese results demonstrated that Huangkui capsule and the flavonoids components prevent tubulointerstitial fibrosis in CRF rat involvement in the action mechanism of inhibiting NADPH oxidase/ROS/ERK pathway.
Graphical abstract
http://ift.tt/2r8fTsS
Scholar : These new articles for Body, Movement and Dance in Psychotherapy are available online
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Scholar : These new articles for Australian Journal of Earth Sciences are available online
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QUILT-3.047: NANT Head and Neck Squamous Cell Carcinoma (HNSCC) Vaccine: Combination Immunotherapy in Subjects With HNSCC Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy
Interventions: Biological: Avelumab; Biological: Bevacizumab; Drug: Capecitabine; Biological: Cetuximab; Drug: Cisplatin; Drug: cyclophosphamide; Drug: 5-Fluorouracil (5-FU); Drug: fulvestrant; Drug: leucovorin; Drug: nab-paclitaxel; Biological: nivolumab; Drug: Lovaza; Radiation: Stereotactic Body Radiation Therapy; Biological: ALT-803; Biological: ETBX-011; Biological: ETBX-021; Biological: ETBX-051; Biological: ETBX-061; Biological: GI-4000; Biological: GI-6207; Biological: GI-6301; Biological: haNK
Sponsor: NantCell, Inc.
Not yet recruiting - verified May 2017
http://ift.tt/2siFSLY
Phase 2 Trial of Apatinib Mesylate in Locally Advanced/Metastatic Differentiated Thyroid Carcinoma
Intervention: Drug: Apatinib Mesylate
Sponsor: Tianjin Medical University Cancer Institute and Hospital
Recruiting - verified March 2017
http://ift.tt/2rkFgIO
Data on coffee composition and mass spectrometry analysis of mixtures of coffee related carbohydrates, phenolic compounds and peptides
Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): Ana S.P. Moreira, Fernando M. Nunes, Cristiana Simões, Elisabete Maciel, Pedro Domingues, M. Rosário M. Domingues, Manuel A. Coimbra
The data presented here are related to the research paper entitled "Transglycosylation reactions, a main mechanism of phenolics incorporation in coffee melanoidins: inhibition by Maillard reaction" (Moreira et al., 2017) [1]. Methanolysis was applied in coffee fractions to quantify glycosidically-linked phenolics in melanoidins. Moreover, model mixtures mimicking coffee beans composition were roasted and analyzed using mass spectrometry-based approaches to disclose the regulatory role of proteins in transglycosylation reactions extension. This article reports the detailed chemical composition of coffee beans and derived fractions. In addition, it provides gas chromatography–mass spectrometry (GC–MS) chromatograms and respective GC–MS spectra of silylated methanolysis products obtained from phenolic compounds standards, as well as the detailed identification of all compounds observed by electrospray mass spectrometry (ESI-MS) analysis of roasted model mixtures, paving the way for the identification of the same type of compounds in other samples.
http://ift.tt/2rh24qM
Experimental data on compressive strength and durability of sulfur concrete modified by styrene and bitumen
Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): M. Dehestani, E. Teimortashlu, M. Molaei, M. Ghomian, S. Firoozi, S. Aghili
In this data article experimental data on the compressive strength, and the durability of styrene and bitumen modified sulfur concrete against acidic water and ignition are presented. The percent of the sulfur cement and the gradation of the aggregates used are according to the ACI 548.2R-93 and ASTM 3515 respectively. For the styrene modified sulfur concrete different percentages of styrene are used. Also for the bitumen modified sulfur concrete, different percentages of bitumen and the emulsifying agent (triton X-100) are utilized. From each batch three 10×10×10cm cubic samples were casted. One of the samples was used for the compressive strength on the second day of casting, and one on the twenty-eighth day. Then the two samples were put under the high pressure flame of the burning liquid gas for thirty seconds and their ignition resistances were observed. The third sample was put into the acidic water and after twenty eight days immersion in water was dried in the ambient temperature. After drying its compressive strength has been evaluated.
http://ift.tt/2qwtA6c
The properties of transparent TiO2 films for Schottky photodetector
Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): Sung-Ho Park, Joondong Kim
In this data, the properties of transparent TiO2 film for Schottky photodetector are presented for the research article, entitled as "High-performing transparent photodetectors based on Schottky contacts" (Patel et al., 2017) [1]. The transparent photoelectric device was demonstrated by using various Schottky metals, such as Cu, Mo and Ni. This article mainly shows the optical transmittance of the Ni-transparent Schottky photodetector, analyzed by the energy dispersive spectroscopy and interfacial TEM images for transparency to observe the interface between NiO and TiO2 film. The observation and analyses clearly show that no pinhole formation in the TiO2 film by Ni diffusion. The rapid thermal process is an effective way to form the quality TiO2 film formation without degradation, such as pinholes (Qiu et al., 2015) [2]. This thermal process may apply to form functional metal oxide layers for solar cells and photodetectors.
http://ift.tt/2rgOjZc
Preparation and catalytic activity of bone-char ash decorated with MgO - FeNO3 for ozonation of reactive black 5 dye from aqueous solution: Taguchi optimization data
Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): Ghorban Asgari, Somaye Akbari, Abdol Motaleb Seid Mohammadi, Ali Poormohammadi, Bahman Ramavandi
Reactive dye is one of the most applicable dyes in textile industries which its release to the water bodies creates a concern for environmentalists. Here, in this data article a bone-char (BC) ash decorated with MgO-FeNO3 for removing reactive black 5 (RB5) dye in a catalytic ozonation process (COP) system. Operational parameters data such as initial RB5 concentration, pH, catalyst dosage, and reaction time were optimized using Taguchi method. The optimal conditions for initial RB5 concentration, pH, catalyst dosage, and reaction time were determined 10mg/L, 10, 0.1g/L, and 15min, respectively. Data of Taguchi optimization tests indicated that the initial RB5 concentration had a significant influence on RB5 removal efficiency (54.03%) during the catalytic ozonation process, and reaction time had lower contribution (2.04%).
http://ift.tt/2qwF21O
Supplementary dataset for child and adult exposure and health risk evaluation following the use of metal- and metalloid-containing costume cosmetics sold in the United States
Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): Angela L. Perez, Melanie Nembhard, Andrew Monnot, Daniel Bator, Elizabeth Madonick, Shannon H. Gaffney
The data presented in this article are related to the research article entitled "Child and adult exposure and health risk evaluation following the use of metal- and metalloid-containing costume cosmetics sold in the United States" [1]. This article describes the concentration of metals and metalloids contained in various cosmetic products such as body paint, lipstick and eye shadow, the relative percent deviation of two analyses performed on the products and the physico-chemico properties of the metals and metalloids used in the SkinPerm model presented in the aforementioned article.
http://ift.tt/2rgwjOB
Data on the anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin in mice
Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): Chang Gun Lee, Eun Ha Lee, Cheol-Ho Pan, Kyungsu Kang, Ki-Jong Rhee
Here, we report animal experimental data associated with the article entitled "AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo" (Jung et al., 2017) [1]. We tested the synergistic anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin hydrochloride in a nude mouse xenograft model of A549 human lung cancer cells. In our experiment, Selaginella tamariscina extract and amentoflavone were administered orally; and doxorubicin hydrochloride was injected intraperitoneally. We expect our preliminary data will be helpful to the development of the anticancer agent using Selaginella tamariscina extract or amentoflavone.
http://ift.tt/2qwFdu3
Data on nation-wide activity in intensive cardiac care units in France in 2014
Publication date: August 2017
Source:Data in Brief, Volume 13
Author(s): François Roubille, Grégoire Mercier, Clément Delmas, Stéphane Manzo-Silberman, Guillaume Leurent, Meyer Elbaz, Adeline Riondel, Eric Bonnefoy-Cudraz, Patrick Henry
We present data in relation to the article entitled "Description of acute cardiac care in 2014:A French nation-wide database on 277,845 admissions in 270 ICCUs".(10.1016/j.ijcard.2017.04.002) (Roubille et al., 2017) [1]: the main characteristics of the pathologies managed in the intensive cardiac care units (ICCUs), the details on the interventions performed and the main differences between centers following the size of the centers and a figure presenting the monthly variations of admissions in the ICCUs in France in a total of 277,845 patients in 270 centers admitted at least one time in the ICCUs in 2014 (exhaustive data).
http://ift.tt/2rgwVnl
Increased TREM-1 expression in inflamed skin has no functional impact on the pathogenesis of cutaneous disorders
Publication date: Available online 30 May 2017
Source:Journal of Dermatological Science
Author(s): Sören Dräger, Kathrin Kalies, Talles B. Sidronio, Mareike Witte, Ralf J. Ludwig, Katja Bieber
http://ift.tt/2rk9con
Overexpression of Human Leukocyte Antigen-G and Interleukin 10 in acral lentiginous melanoma
Publication date: Available online 29 May 2017
Source:Journal of Dermatological Science
Author(s): M. Zúñiga Castillo, N.V. Pereira, F. Guedes, M.N. Sotto
http://ift.tt/2sinK5a
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Publication date: September 2017 Source: Free Radical Biology and Medicine, Volume 110 Author(s): Lucía Fernández-del-Río, Anish Nag, Elen...
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Abstract Noise pollution is a major factor of environmental complaints in many cities, which has significant impacts on human health. As a...
