The association between adolescent cannabis use and anxiety: A parallel process analysis

Publication date: March 2018
Source:Addictive Behaviors, Volume 78
Author(s): Jacqueline Duperrouzel, Samuel W. Hawes, Catalina Lopez-Quintero, Ileana Pacheco-Colón, Jonathan Comer, Raul Gonzalez
IntroductionAssociations between anxiety symptoms and cannabis use have been previously explored, yet the directionality of these associations remains highly debatable. The present study aims to prospectively examine patterns of cannabis use and anxiety during adolescence focusing on their co-development and bidirectional influences.MethodsAdolescents (n=250) of predominantly Hispanic ethnicity, aged 14–17 at baseline, exposed to drugs, alcohol, or cigarettes completed three (bi-annual) assessments across a 1-year period. Latent growth curve modeling (LGCM) and parallel process growth curves were conducted to examine potential associations in the joint development of anxiety and cannabis use.ResultsOur results suggest that, during adolescence, early cannabis use has a greater influence on prospective reports of anxiety, than vice versa. Specifically, adolescents exhibiting higher initial levels of cannabis use displayed more persisting self-reported anxiety across time, as compared to those with less frequent use (b=0.28, p=0.024). In contrast, early levels of anxiety were not found to influence rates of change in cannabis use. These analyses considered concurrent depression, alcohol, and nicotine use.ConclusionsOur findings suggest that prevention and targeted intervention programs for cannabis use in adolescence would benefit from anxiety management strategies; in order to reduce subsequent anxiety associated with cannabis use. Future studies should continue to employ longitudinal designs across larger time periods and aim to replicate these findings with more diverse samples.



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Scholar : These new articles for Canadian Journal of Latin American and Caribbean Studies / Revue canadienne des études latino-américaines et caraïbes are available online

The online platform for Taylor & Francis Online content New for Canadian Journal of Latin American and Caribbean Studies/Revue canadienne des études latino-américaines et caraïbes and online now on Taylor & Francis Online: Errata Erratum Pages: 1-1 | DOI: 10.1080/08263663.2018.1404233 Find out more about the issues and challenges in Governing Asia. This collection includes free access papers on security challenges, the Abe and Modi administration, reflections on the Chinese Governance and more. Browse today! To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for International Journal of Performance Arts and Digital Media are available online

The online platform for Taylor & Francis Online content New for International Journal of Performance Arts and Digital Media and online now on Taylor & Francis Online: Original Articles Archive everything: mapping the everyday Zeta Kolokythopoulou Pages: 1-2 | DOI: 10.1080/14794713.2017.1401870 To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Scholar : These new articles for Canadian Society of Forensic Science Journal are available online

The online platform for Taylor & Francis Online content New for Canadian Society of Forensic Science Journal and online now on Taylor & Francis Online: Original Articles Digital dermatoglyphic study in three west Algerian populations: Reguibates, Zenata, Oran Leïla Adda Neggaz, Djabaria Naima Meroufel, Tahria Deba, Asmahan Bekada, Mohamed Hammadi, Sounnia Mediene Benchekor, Araceli Rosa & Soraya Benhamamouch Pages: 1-11 | DOI: 10.1080/00085030.2017.1379267 To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Spatiotemporal patterns and source attribution of nitrogen pollution in a typical headwater agricultural watershed in Southeastern China

Abstract

Excessive nitrogen (N) discharge from agriculture causes widespread problems in aquatic ecosystems. Knowledge of spatiotemporal patterns and source attribution of N pollution is critical for nutrient management programs but is poorly studied in headwaters with various small water bodies and mini-point pollution sources. Taking a typical small watershed in the low mountains of Southeastern China as an example, N pollution and source attribution were studied for a multipond system around a village using the Hydrological Simulation Program-Fortran (HSPF) model. The results exhibited distinctive spatio-seasonal variations with an overall seriousness rank for the three indicators: total nitrogen (TN) > nitrate/nitrite nitrogen (NO_x⁻-N) > ammonia nitrogen (NH₃-N), according to the Chinese Surface Water Quality Standard. TN pollution was severe for the entire watershed, while NO_x⁻-N pollution was significant for ponds and ditches far from the village, and the NH₃-N concentrations were acceptable except for the ponds near the village in summer. Although food and cash crop production accounted for the largest source of N loads, we discovered that mini-point pollution sources, including animal feeding operations, rural residential sewage, and waste, together contributed as high as 47% of the TN and NH₃-N loads in ponds and ditches. So, apart from eco-fertilizer programs and concentrated animal feeding operations, the importance of environmental awareness building for resource management is highlighted for small farmers in headwater agricultural watersheds. As a first attempt to incorporate multipond systems into the process-based modeling of nonpoint source (NPS) pollution, this work can inform other hydro-environmental studies on scattered and small water bodies. The results are also useful to water quality improvement for entire river basins.

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Extended Spectrum Beta-Lactamase (ESBL)-producing bacteria isolated from hospital wastewaters, rivers and aquaculture sources in Nigeria

Abstract

Untreated wastewater is a risk factor for the spread of antibiotic resistance in the environment. However, little is known about the contribution of untreated wastewater to the burden of antibiotic resistance in the Nigerian environment. In this study, a total of 143 ceftazidime-/cefpodoxime-resistant bacteria isolated from untreated wastewater and untreated wastewater-contaminated surface and groundwater in Nigeria were screened for extended-spectrum β-lactamase (ESBL) genes, integrons and integron gene cassettes by PCR. The genetic environment of bla _CTX-M-15 was mapped by PCR and potentially conjugative plasmids were detected among the isolates by degenerate primer MOB typing (DPMT). ESBL production was confirmed in 114 (79.7%) isolates and ESBL genes (bla _SHV, bla _CTX-M-15 and bla _TEM) were detected in 85 (74.6%) ESBL-producing isolates. bla _CTX-M-15 was associated with ISEcp1 and with orf477 in 12 isolates and with ISEcp1, IS26 and orf477 in six others. To the best of our knowledge, this is the first report of bla _CTX-M-15 in hand-dug wells and borehole serving as sources of drinking water and a first report of the genetic environment of bla _CTX-M-15 in environmental bacteria from Nigeria. The results of this study confirm untreated wastewater as an important medium for the spread of ESBL-producing bacteria within the Nigerian environment. Hence, the widespread practice of discharging untreated wastewater into the aquatic ecosystem in Nigeria is a serious risk to public health.

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Scholar : These new articles for Canadian Water Resources Journal / Revue canadienne des ressources hydriques are available online

The online platform for Taylor & Francis Online content New for Canadian Water Resources Journal / Revue canadienne des ressources hydriques and online now on Taylor & Francis Online: Original Articles Benefits and limitations of using isotope-derived groundwater travel times and major ion chemistry to validate a regional groundwater flow model: example from the Centre-du-Québec region, Canada Sylvain Gagné, Marie Larocque, Daniele L. Pinti, Marion Saby, Guillaume Meyzonnat & Pauline Méjean Pages: 1-19 | DOI: 10.1080/07011784.2017.1394801 Municipal flood risk sharing in Canada: A policy instrument analysis Jason Thistlethwaite & Daniel Henstra Pages: 1-15 | DOI: 10.1080/07011784.2017.1364144 Browse articles in this special issue on: 'Advancements in Civil and Structural Engineering' To update which email alerts you receive, manage your alerts within the My Account area. You can also unsubscribe from this alert with one click. If you need any further help, please contact us at support@tandfonline.com Please do not reply to this email. To ensure that you receive your alerts and information from Taylor & Francis Online, please add "alerts@tandfonline.com" and "info@tandfonline.com" to your safe senders list. Taylor & Francis, an Informa business. Taylor & Francis is a trading name of Informa UK Limited, registered in England under no. 1072954. Registered office: 5 Howick Place, London, SW1P 1WG.

Slowly Enlarging Nodule on the Chest

No abstract available

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Cutaneous Collagenous Vasculopathy: A Unique Case With Positive Direct Immunofluorescence Findings

No abstract available

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Unusual Case of Combined Gliomeningeal Heterotopia on the Nose of an Infant

Abstract: Nasal glial heterotopia ("nasal glioma") and cutaneous heterotopic meningeal nodules ("primary cutaneous meningioma") are rare congenital lesions characterized by the presence of heterotopic mature cerebral tissues. Nasal glial heterotopia occurs predominantly in the nasal area and typically does not contain meningothelial elements, whereas heterotopic meningeal nodules occur predominantly on the scalp and do not contain glial elements. In this article, we report an unusual case of cutaneous heterotopia on the nose of an infant composed of both glial and meningothelial elements. The glial component was characterized by irregular islands of predominantly astrocytic cells, on a fibrillary background. The meningothelial component was characterized by bland ovoid cells with focal intranuclear inclusions forming whorled arrangements, with associated psammomatous calcification. To our knowledge, this is the first time such a lesion has been documented. It has also provided us with an opportunity to review the literature regarding heterotopic deposits of both glial and meningothelial tissues. Reprints: Benjamin A. Wood, FRCPA, Department of Anatomical Pathology, PathWest, QEII Medical Centre, Hospital Avenue, Nedlands, Western Australia 6009, Australia (e-mail: benjamin.wood@health.wa.gov.au). The authors declare no conflicts of interest. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

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Digital Apocrine Hidrocystoma: The Exception Confirms the Rule

No abstract available

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Immunohistochemical and Fluorescence In Situ Hybridization Analysis of MYC in a Series of 17 Cutaneous Angiosarcomas: A Single-Center Study

Abstract: Cutaneous angiosarcoma (AS) is an uncommon aggressive sarcoma whose incidence is rising because of the increasing use of radiation therapy, especially in breast cancer. The few studies on the relevance of prognostic factors, such as MYC status in cutaneous AS, have reported inconclusive findings, with some authors reporting MYC amplification only in postirradiation and lymphedema-associated AS and others reporting evidence of MYC amplification in idiopathic AS. We analyzed 17 cases of cutaneous AS (6 idiopathic AS, 10 postirradiation AS, and 1 lymphedema-associated AS) treated at our institute between 2000 and 2015. Follow-up data were available in all cases. We compared the presence/absence of MYC amplification by fluorescence in situ hybridization (FISH) and immunohistochemical (IHC) MYC overexpression in the different AS subtypes. We also investigated potential associations between MYC amplification and prognosis. MYC amplification was observed by FISH in 6 of 14 informative cases. The positive cases were all secondary AS (5 postirradiation AS and 1 lymphedema-associated AS). IHC detected MYC overexpression in 8 of 15 informative cases (7 secondary AS and 1 idiopathic AS). In conclusion, MYC amplification and MYC overexpression were detected almost exclusively in secondary AS. No associations were found between MYC amplification/overexpression and prognosis. We found MYC amplification or overexpression in a similar proportion of the patients who died and who were still alive at the end of the study. In the group of 9 patients who died, MYC was detected by FISH in 4 cases and by IHC in 5. The corresponding figures in the group of 6 patients still alive were 2 by FISH and 3 by IHC. Reprints: Celia Requena, MD, Department of Dermatology, Instituto Valenciano de Oncología, c/Profesor Beltrán Báguena, 8, 46009 Valencia, Spain (e-mail: celiareq@hotmail.com). The authors declare no conflicts of interest. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

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New Histologic Finding of Amyloid Insulin Bodies at an Insulin Injection Site in a Patient With Diabetes

Abstract: Amyloidosis is a heterogeneous group of protein deposition diseases with more than 40 known clinical presentations. Localized amyloidosis occurs when the protein deposits exist in a singular location. Patients with diabetes mellitus who inject insulin at the same site can develop localized insulin-derived amyloidosis (AIns) at the injection site, which can be confused clinically with lipoma, lipohyperplasia, lipoatrophy, and fat necrosis. Histologic examination is performed to confirm localized AIns. We report a case of a patient with a long history of type 2 diabetes who presented with a subcutaneous mass in the abdomen at a preferred insulin injection site. Examination by light microscopy revealed diffuse deposition of eosinophilic material. Two of the tissue fragments contained numerous 30–40 μm spherical bodies within the eosinophilic material. The bodies had dark centers with peripheral eosinophilic material. Polarized sections stained with Congo red showed apple green birefringence, a characteristic of amyloid. Immunohistochemistry was positive for insulin antibodies in the dark spherules and the surrounding matrix. Proteomic analysis by mass spectrometry showed that the Congo red–positive material was insulin. Electron microscopy showed a background matrix consisting of nonbranching protein fibrils measuring 8.8–16.1 nm, consistent with amyloid; the spherules contained dark globular proteins in the center surrounded by nonbranching fibrillary proteins. Because these spherules were positive for insulin by immunohistochemistry and showed amyloid ultrastructurally, we refer to them as amyloid insulin bodies. The identification of AIns, specifically with amyloid insulin bodies, is important for diagnosis and treatment and may further our understanding of amyloidogenesis. Reprints: Paul Medline, MD, FRCPC, Dynacare Laboratory and Health Services Centre, 115 Midair Court, Brampton, ON L6T 5M3, Canada (e-mail: pmedline@hotmail.com). The authors declare no conflicts of interest. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

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Unilesional Follicular Mycosis Fungoides: Report of 6 Cases and Review of the Literature

Abstract: Unilesional follicular mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma characterized by selective involvement of the hair follicles by neoplastic T lymphocytes presenting initially as a solitary lesion occupying less than 5% of the body surface; there are 22 previous reported cases. We describe 6 patients with this rare variant of MF, all males (age range 6–64 years; mean age: 28 years) presenting with a solitary lesion primarily on the face and scalp except 1 patient who presented with a truncal lesion. All the patients had the lesions for at least a few months. The lesions were associated with follicular prominence and hair loss. In each, the biopsies showed an atypical folliculotropic lymphocytic infiltrate accompanied by follicular mucinosis in certain cases. The infiltrate involved the lower isthmic part of the follicle, and in 1 case, there was an alopecia areata-like neoplastic lymphomatoid bulbitis. There was no evidence of large cell transformation nor was there a significant degree of infiltration of the interfollicular dermis or epidermis. Higher magnification disclosed marked cerebriform atypia amidst the lymphocytes. Phenotypic studies demonstrated a high CD4 to CD8 ratio in excess of 5 with a significant loss of CD7. One patient developed additional similar lesions involving the thigh and buttock after a period of at least 3–4 years of untreated unilesional MF. Unilesional follicular MF is a potentially curable form of MF with a young male predilection. Early diagnosis and treatment intervention likely define a cornerstone for ensuring the best patient outcome and preventing clinical evolution to either tumor stage MF and or multilesional MF. Reprints: Cynthia M. Magro, MD, Professor of Pathology and Laboratory Medicine, Professor of Dermatopathology in Dermatology, Director of Dermatopathology, Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 1300 York Avenue, F-309, New York, NY 10065 (e-mail: cym2003@med.cornell.edu). The authors declare no conflicts of interest. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

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Violaceous Pink Axillary and Intertriginous Patches

No abstract available

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Cytokeratin Profile of Basal Cell Carcinomas According to the Degree of Sun Exposure and to the Anatomical Localization

Abstract: Basal cell carcinoma (BCC) seems to originate from ultraviolet light-induced mutations involving the bulge or the outer sheath of the hair follicle cells. However, the etiopathogenic mechanisms involved in the development of these tumors in nonphotoexposed and in hairless areas remain unclear. The cytokeratin (CK) profile (including CK5/6, CK7, CK14, CK15, CK17, and CK19) from a series of different BCC subtypes developing in sun-exposed and non–sun-exposed areas, including hairless regions, was evaluated. The authors have observed that CK7 expression in BCC is associated with the anatomical localization of the tumor and its sun-exposition, but not with other factors such as histological subtype. The expression of this CK is higher in BCCs located in non–sun-exposed and nonhairy areas, such as the vulvar semimucosa and the nipple. Because CK7 is a marker of simple glandular epithelia, the authors suggest a glandular origin for BCCs located in hairless and nonphotoexposed areas. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. Reprints: Ma Reyes García-de-la-Fuente, MD, Department of Dermatology, University Hospital Arnau de Vilanova, Avenida Alcalde Rovira Roure, 80, 25198 Lleida, Spain (e-mail: mrgarcia_dlf@hotmail.com). The authors declare no conflicts of interest. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (http://ift.tt/2hxkbZ3). Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

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Mycosis Fungoides Manifesting as Giant Cell Lichenoid Dermatitis

Abstract: Mycosis fungoides (MF) is the most common form of primary cutaneous lymphoma with a broad clinicopathological spectrum. Unusual histopathologic patterns of MF include lichenoid, interstitial, folliculotropic, spongiotic, granulomatous, and many others. Several cases of unusual lichenoid reaction characterized by a mixed lichenoid inflammatory infiltrate with prominent infiltration of the papillary dermis and epidermis by multinucleated giant cells were described under the name of "giant cell lichenoid dermatitis," most of them were considered to represent a drug eruption. Herein, we describe a 77-year-old woman with a 5-year history of MF displaying microscopic features of giant cell lichenoid dermatitis. Histology revealed a dense band-like lichenoid epidermotropic infiltrate composed of CD4+ small to medium-sized lymphocytes with cerebriform nuclei with the presence of multinucleated giant cells in the papillary dermis, within the epidermis, and some hair follicles. Monoclonal TCR gene rearrangement was detected using PCR. To the best of our knowledge, this pattern was never described in MF. Reprints: Dmitry V. Kazakov, MD, PhD, Sikl's Department of Pathology, Charles University Medical Faculty Hospital, Alej Svobody 80, 304 60 Pilsen, Czech Republic (e-mail: kazakov@medima.cz). The authors declare no conflicts of interest. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

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The Crown Jewel, an Enigmatic Solitary Mass of Follicular Origin: Challenge

No abstract available

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Investigation of the effects of slow-release fertilizer and struvite in biodegradation in filter drains and potential application of treated water in irrigation of road verges

Abstract

Filter drains are usually laid along the margins of highways. Highway runoffs are polluted with hydrocarbons and high levels of total dissolved solids. Therefore, effective pollution removal mechanism is necessary in order to avoid contamination of surrounding soils and groundwater. Biodegradation is amongst pollution removal mechanisms in filter drains, but it is a relatively slow process which is dependent on wide range of factors including the type of pollutant and availability of nutrients. This paper reports on a study conducted to investigate the impact of slow-release fertilizer and struvite in enhancement of biodegradation of hydrocarbon in filter drains. Filter drain models incorporated with geotextile were challenged with cumulative oil loading of 178 mg/m²/week with a view to comparing the efficiency of these two nutrient sources under high oil pollution loading and realistic rainfall conditions of 13 mm/week. Nutrients and street dust were applied at one-off rate of 17 g/m² and 1.55 g/rig to provide nutrient enhancement and simulate field conditions respectively. The impact of the nutrients was studied by monitoring bacterial and fungal growth using nutrient agar, Rose Bengal Agar media and CO2 evolution. EC, pH, heavy metals, TPH, elemental analysis and SAR were used to investigate water quality of effluent of filter drains for potential application as irrigation fluid for trees and flowers planted on road verges. The results show that nutrient application encouraged microbial activities and enhanced biodegradation rates with differences in type of nutrient applied. Also, it was observed that incorporation of geotextiles in filter drains improved pollution retention efficiency and there is a potential opportunity for utilization of struvite in SuDS systems as sustainable nutrient source.

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Curing brain metastases

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