Ιατρικά Άρθρα

Πέμπτη 12 Ιουλίου 2018

Issue Information

Helicobacter, Volume 23, Issue 4, August 2018.

https://ift.tt/2Ji8M7c

Phase II study of accelerated Linac-based SBRT in five consecutive fractions for localized prostate cancer

Abstract

Aim

The goal was to evaluate feasibility, side effects and biochemical no evidence of disease (bNED) after stereotactic body radiation therapy (SBRT) delivered on 5 consecutive days for localized prostate cancer (PC).

Methods

The study was approved by the ethical committee and started in March 2014. Inclusion criteria were age ≤85 years, WHO performance status ≤2, histologically proven adenocarcinoma, low–intermediate risk, no previous surgery (except transurethral resection of the prostate), and a pre-SBRT International Prostatic Symptoms Score of 0–7. The radiotherapy regimen consisted of 35 Gy for low-risk and 37.5 Gy for intermediate-risk PC in 5 consecutive fractions.

Results

At the time of the analysis, 52 patients were recruited to the study (median age 73 years, range 55–83 years; median follow-up 34 months, range 12–49 months; 34 patients low-risk and 18 intermediate risk). The median initial prostate-specific antigen (PSA) was 5.9 ng/ml (range 1.8–15.7). Acute genitourinary (GU) toxicity was G0 (grade 0) 36/52 (69%), G1 11/52 (21%), G2 5/52 (10%), while acute rectal (GI) toxicity was G0 43/52 (83%), G1 8/52 (15%), G2 1/52 (2%). No acute toxicity ≥G3 was recorded. At the time of analysis late GU and GI toxicities were as follows: GU-G0 43/52 (83%), GU-G1 7/52 (13%), GU-G2 2/52 (4%); GI-G0 48/52 (92%), GI-G1 2/52 (4%), GI-G2 2/52 (4%). No late toxicities ≥G3 were recorded. bNED was 98%. One patient with intermediate PC had distant progression.

Conclusions

Accelerated SBRT for low-intermediate PC is feasible and well tolerated with comparable oncological outcome as described for other series with the same RT technique but treatment delivery on every other day. Longer follow-up is needed to the assess late toxicity profile and long-term clinical outcome.

https://ift.tt/2JgNoyZ

Psoriasis and cancer. An Australian/New Zealand narrative

Australasian Journal of Dermatology, EarlyView.

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Exome sequencing identifies novel compound heterozygous mutations in GJB3 gene that cause erythrokeratodermia variabilis et progressiva

Australasian Journal of Dermatology, EarlyView.

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Liver Biochemical Abnormalities in Turner Syndrome: a Comprehensive Characterisation of an Adult Population

Clinical Endocrinology, Volume 0, Issue ja, -Not available-.

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Inter‐related effects of insulin resistance, hyperandrogenism, sympathetic dysfunction and chronic inflammation in PCOS

Clinical Endocrinology, Volume 0, Issue ja, -Not available-.

https://ift.tt/2KTvxEl

Hiding in a plain sight: a high prevalence of androgen deficiency due to primary hypogonadism among acute medical inpatients with anaemia

Clinical Endocrinology, Volume 0, Issue ja, -Not available-.

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Thyroid Storm and Complete Heart Block after Treatment with Radioactive Iodine.

Thyroid Storm and Complete Heart Block after Treatment with Radioactive Iodine.

Case Rep Endocrinol. 2018;2018:8214169

Authors: Vennard K, Gilbert MP

Abstract
Thyroid storm is a rare endocrine emergency characterized by dysfunction of multiple organ systems. Thyroid storm is more common in Graves' disease and can be precipitated by surgery, trauma, infection, metabolic abnormalities, iodine load, and parturition. We present a diagnostically challenging case of thyroid storm precipitated by radioiodine therapy and accompanied by bradycardia, a rare but life-threatening complication related to treatment for hyperthyroidism.

PMID: 29992062 [PubMed]

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Role of AMPA and NMDA receptors on vasopressin and oxytocin secretion induced by hypertonic extracellular volume expansion

Journal of Neuroendocrinology, Volume 0, Issue ja, -Not available-.

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EEMCO—European group on efficacy measurement and evaluation of cosmetics and other products

Skin Research and Technology, Volume 24, Issue 3, Page 349-350, August 2018.

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Issue Information

Skin Research and Technology, Volume 24, Issue 3, Page i-iv, August 2018.

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Rare clinical manifestations of leukemia cutis

Journal of Cutaneous Pathology, Volume 0, Issue ja, -Not available-.

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Epithelial barrier dysfunctions in atopic dermatitis: a skin–gut–lung model linking microbiome alteration and immune dysregulation

British Journal of Dermatology, EarlyView.

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In situ bio‐distribution and residency of a topical anti‐inflammatory using fluorescence lifetime imaging microscopy

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.

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Stratum corneum analysis provide a minimal invasive tool to study immune response and skin barrier in atopic dermatitis children

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.

https://ift.tt/2mcOYcp

Quality of life in patients with acquired pigmentation: An observational study

Journal of Cosmetic Dermatology, EarlyView.

https://ift.tt/2L7nMqd

Nonsurgical treatment of earlobe aging in Mowlawi stages I and II earlobe ptosis with Hyaluronic acid fillers

Journal of Cosmetic Dermatology, EarlyView.

https://ift.tt/2NJqpAk

Scholar : Undersea "Hyperbaric Medicine" - νέα αποτελέσματα

Hyperbaric Oxygen Therapy in Emergency Medicine

P Nicholson, C San Miguel, CG Kaide… - Emergency Medicine …, 2018

… In 1967, the Undersea and Hyperbaric Medicine Society (UHMS) was
founded to promote the exchange of HBO data and research. The UHMS
periodically issues guidelines on the practice of hyperbaric medicine. 1 …

Δημιουργία λίστας των ειδοποιήσεών μου

Ακύρωση ειδοποίησης

Αυτή η ειδοποίηση αποστέλλεται από τον Μελετητή Google. Ο Μελετητής Google είναι μια υπηρεσία που παρέχεται από την Google.

Scholar : ΣΤΟΜΑΤΙΤΙΣ - νέα αποτελέσματ

[PDF] Beneath the Complete Denture Prosthesis: A Review

N Jenny - International Journal, 2018

… level. Keywords: mucosal effect, denture stomatitis, denture sore, tissue conditioner …
denture. Denture sore mouth/stomatitis is a pathological reactions of the denture bearing
palatal mucosa. It is also called as denture induced stomatitis …

Aqueous extract of Sedum oxypetalum induces mineralization and osteogenic differentiation by human Periodontal Ligament-Derived cells

GR Lara-Issasi, NE Ocampo, L Hoz-Rodríguez… - Journal of …, 2018

… 2016). For example, recent studies have shown that plant-derived bioactive
compounds can be effective in treating diseases such as stomatitis and periodontal
disease (Kala et al., 2015, Trivedi and Dixit, 2015). Periodontitis …

[PDF] Síndrome de Stevens-Johnson en edad pediátrica

P Paredes - Revista científica, 2018

… pathogenetic, histological and therapeutic aspects, that endanger the patient's
life. The affection is characterized by a sudden morphologically varying rash,
accompanied by stomatitis and ophthalmic injure. In this work we show an …

Investigating the Role of PARP-1 in HIV-1 Replication

SR Garcia - 2018

… receptors. Replacement of the HIV-1 native envelope by the Vesicular Stomatitis Virus …
with calcium-phosphate of 15ug of the plasmid of interest expressing either Cas9 or the
PARP-1-specific sgRNA, 5ug of Vesicular Stomatitis Virus glycoprotein G (VSV-G) and …

[PDF] Insecticide Resistance in Insect Vector of Human Disease

T Alam - 2018

… Mites Rickettsioses, Q fever Fleas Endemic typhus Sandflies Leishmaniasis,
Sandfly fever, Vesicular stomatitis Page 9. (Source: Modified from William
et al.,1998 & Kalluri et al.,2007) 3.2 Insecticide Resistance in Insect Vectors …

[PDF] Outbreak of PPR in an Organised Goat Farm in Theni District of Tamilnadu

A Senthilkumar, P Balamurugan, N Sribalaji… - Young

… respectively (1,2). It is a highly contagious, infectious and fatal viral disease
of small ruminants (3,4). Other names commonly used includes, pseudo
rinderpest of small ruminants; pest of small ruminants; goat plague; pest of …

Informed consent to medical treatment in pediatric dentistry: a proposal for two new model forms for the public health care system

CM De Sanctis - Annali di Stomatologia, 2018

… 1.4.) RISKS AND CONTRAINDICATIONS OF PRESCRIBED THERAPIES: sensitivity
to used materials; contact allergy leading to stomatitis, lichenoid eruptions, contact
allergy to rubber dental dam leading the dermatitis. I declare …

Biofilms of Candida albicans and Streptococcus sanguinis and their Susceptibility to Antimicrobial Effects of Photodynamic inactivation

AL do Rosário Palma, L de Paula Ramos… - … and Photodynamic Therapy, 2018

… In the study by Pereira et al. [23], who used the same protocol, PDI produced
reductions of 4.62 ± 1.06 and 1.01 ± 0.44 log 10 , in planktonic cultures and
biofilms of 20 strains of C. albicans isolated from individuals with denture …

Interferon-stimulated genes: new platforms and computational approaches

R Green, RC Ireton, M Gale - Mammalian Genome, 2018

… Researchers applied bioinformatics approaches to analyze transcriptional
data sets generated from studies from non- human primates undergoing
vaccination with a Vesicular stomatitis virus-based Zaire Ebola virus (EBOV) …

[PDF] Efeito fotossenssibilizador in vitro da violeta de genciana na terapia fotodinâmica sobre Candida albicans

RC de Queiroz Pinheiro, M Sousa Peixoto… - … , Ciclos de Vida e Saúde no …, 2018

… 12. Maver-Biscanin M, Mravak-Stipetic M, Jerolimov V, Biscanin A. Fungicidal
effect of diode laser irradiation in patients with denture stomatitis … Effectiveness
of microwave disinfection of complete dentures on the treatment of …