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Πέμπτη 1 Νοεμβρίου 2018
Psychometric properties of the Iranian version of mindful eating questionnaire in women who seeking weight reduction
Abstract
Background
The aim of the present study was to test the validity, reliability and factor structure of the original Mindful Eating Questionnaire (MEQ) for use in an Iranian population.
Methods
This was a cross-sectional study conducted on 150 women who attended four athletic gyms and met the inclusion criteria in Ahvaz city in July of 2015. After linguistic validation of the Iranian version of the MEQ, the content validity ratio (CVR) and content validity index (CVI) were assessed by an expert panel. Then, exploratory factor analysis (EFA) was performed on the scale constructs and scale reliability (internal consistency and test-retest reliability) was assessed with respect to the psychometric properties of the scale.
Results
The CVR and CVI scores for the MEQ were 0.89 and 0.93, respectively. EFA loaded all 28-items with a 5-factor solution ('awareness', 'distraction', 'disinhibition', 'emotional response' and 'external cues') that jointly accounted for 53.78% of the observed variance. The results of the EFA supported the item 'When a restaurant portion is too large, I stop eating when I'm full' being placed in the external cues rather than the disinhibition subscale. This displacement improved the reliability coefficient for this subscale.
The results of internal consistency analysis, including Cronbach's alpha (ranging from 0.73 to 0.81) and intraclass correlation coefficients (ranging from 0.73 to 0.91) were satisfactory.
Conclusions
The Persian version of the MEQ appears to be valid and reliable; therefore, it can be an effective tool in designing mindfulness-based interventions for the treatment of individuals with eating disorders, overweight and obesity in an Iranian population.
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Single surgeon series of outcomes of 897 consecutive endoscopic carpal tunnel releases stratified by disease severity
The safety and efficacy of multiple endoscopic carpal tunnel (eCTR) techniques have been established in the literature.1-3 High rates of symptomatic relief and low risk of complications are reported, similar to those seen with open CTR.2 A stratification of postoperative results and relief of carpal tunnel syndrome (CTS) based on objective pre-operative disease severity has not been established. This information would allow more individualized preoperative counselling.
https://ift.tt/2CV8gMS
Effects of pedicle torsion on dynamic perforasome survival in a multi-territory perforator flap model: An experimental study
Necrosis of propeller flaps is a problem in clinical practice. This study was performed to investigate the effects of pedicle torsion on dynamic perforasome survival using a multi-territory perforator flap model in rats.
https://ift.tt/2P5cx7N
Microvascular Anastomotic Coupler Application Learning Curve: A curriculum supporting further deliberate practice in Ex-vivo Simulation models
Microvascular anastomosis with coupler devices revolutionized microsurgery practice. Couplers are considered easier to apply and offer improved operating time while maintaining success rates. This study aims to map the learning curve, skill acquisition and decay of novice microsurgeons in performing coupler anastomosis.
https://ift.tt/2CXGkYV
A retrospective study on surgical outcomes and patient satisfaction of EGIS® ADM in one-stage implant-based breast reconstruction
Implant-based breast reconstruction (IBBR) is the most performed breast reconstruction method. It is performed either as a one-stage (i.e. direct-to-implant) or two-stage (expander/implant) procedure. In both methods, an acellular dermal matrix (ADM) can be used. The ADM provides support of the implant and improves implant coverage, which facilitates a one-stage reconstruction and results in a more natural ptotic breast.1 Reported complication rates after IBBR with an ADM vary widely, from less than 5% up to 50%.
https://ift.tt/2P8nBBe
A Quantitative Analysis of Factors Influencing Lower Lid Retraction and Involutional Ectropion
Laxity of the eyelid can be evaluated by a subjective assessment during manipulation and distraction, using procedures such as the "pinch test" and "snap back test".1 To our knowledge, no study has objectively measured the force exerted to induce eyelid malposition during such testing. We conducted a quantitative analysis to record the minimum force that can induce lower eyelid ectropion and displacement in four different demographic groups (age, gender, race, and orbital vectors).
https://ift.tt/2CV7rDM
Biomechanical behavior of mandibles reconstructed with fibular grafts at different vertical positions using finite element method
For large mandibular defects, surgical reconstruction using microvascular fibular grafts has advantages over other alternatives in terms of blood supply and good quality of grafted bone. However, the fibular segment is usually lower in height than that of the original mandible, meaning that the vertical positioning of the fibular graft is variable, with different biomechanical consequences on the reconstructed mandible.
https://ift.tt/2OZNrae
A feasibility study of indocyanine green fluorescence mapping for sentinel lymph node detection in cutaneous melanoma
Sentinel lymph node biopsy (SLNB) is standard of care for staging regional LN in AJCC stage IB-IIC melanoma; using dual localization with radiolabelled colloid and blue dye. Combining these gives optimal accuracy; drawbacks include cumulative radiation exposure for healthcare workers, coordination between disciplines and anaphylaxis. An alternative tracer agent is indocyanine green (ICG); an optical enhancer that fluoresces in the near infrared range. This prospective cohort study assesses the feasibility of using ICG as a tracer agent to detect SLN in cutaneous melanoma.
https://ift.tt/2CZ1QMy
Novel technique of filler injection in the temple area using the vein detection device
The increasing popularity of soft tissue fillers will inevitably result in increasing incidence of vascular injury. The temple area consists of several layers such as the superficial subcutaneous layer, superficial temporal fascia, loose areolar tissue, deep temporal fascia, temporalis muscle, and temporal bone from the zygomatic arch to the superior temporal septum. Fillers can be injected into various layers: first, the superficial subcutaneous layer; second, between the superficial temporal fascia and deep temporal fascia; and third, above the periosteum of the temporal bone.
https://ift.tt/2P48qZB
Local safety of immediate reconstruction during primary treatment of breast cancer. Direct-to-implant versus expander-based surgery
After mastectomy, immediate breast reconstruction is paramount. With the growing number of nipple-sparing mastectomies, also the chances of successful one-stage reconstruction with implants are increasing. Local safety is one of the main issues. This study investigated which factors could lead to major or minor complications after expander-based versus direct-to-implant reconstruction.
https://ift.tt/2CZ1Mwi
Differential Visualization of Arterial and Venous Flow in Deep Inferior Epigastric Perforator Imaging with Vector-Flow Perforator Phase Contrast Angiography (pPCA)
Perforator flaps are commonly used in reconstructive surgery, with decreased donor site morbidity and increased flexibility in flap design cited as advantages over traditional techniques.1 Vascular imaging is often obtained preoperatively in order to facilitate flap design and execution.2-3 Computed tomographic angiography (CTA) is widely used in a variety of different perforator flaps, but possesses a number of drawbacks. CTA utilizes ionizing radiation, which is of particular concern to the patient population receiving perforator flap surgery as many of them are young and with greater than usual susceptibility to radiation induced neoplasia due to risk factors such as BRCA gene mutations and Li-Fraumeni Syndrome.
https://ift.tt/2P48qJ5
Individualized small-incision orbicularis-levator fixation blepharoplasty for unilateral single-eyelid Asians
Unilateral double-eyelid blepharoplasty is often required by people with unilateral single eyelid. The full incisional method may cause permanent skin scar formation, and the buried suture method may lead to early eyelid fold loosening, which could not reduce the eyelid's soft tissue thickness. A total of 85 patients (8 males, 77 females) with unilateral single eyelid were involved between January 2015 and January 2016, with a mean age of 25.57±6.5 years. Small-incision orbicularis-levator fixation blepharoplasty was performed on all patients on the single eyelid side.
https://ift.tt/2CZ1BkC
The Impact of Facial Expression on Facial Appearance of the Surgically Managed Unilateral Cleft Lip and Palate Patients (UCLP)
To evaluate the impact of facial expression on the asymmetry of surgically managed UCLP cases.
https://ift.tt/2P5FBfc
A Large-Volume Academic Center Retrospective Audit of The Temporal Evolution of Immediate Breast Reconstruction Protocols and the Effect on Breast Prosthetic Infection
Complications of tissue expanders (TE) in breast reconstruction are challenging. We sought to identify TE infection risks and acellular dermal matrix (ADM) and infection control protocol impacts on infection in a longitudinal study.
https://ift.tt/2CVcqnW
Sentinel node biopsy for melanoma: New Zealand indication guidelines in practice
Current New Zealand cutaneous melanoma management guidelines1 note thin melanomas (<1mm) can usually be cured by primary tumour removal, and while unnecessary in most cases, sentinel node biopsy (SNB) may be considered for patients with poor prognostic factors, such as ulceration or dermal mitoses (T1b2). For patients with intermediate thickness melanomas (1–4mm: T2 and T3), it is suggested SNB is useful for identifying small nodal metastases, allowing more accurate staging, better prognostication and improved regional tumour control.
https://ift.tt/2P4NxNN
Association of benign thyroid diseases with thyroid cancer risk: a meta-analysis of prospective observational studies
Abstract
Purpose
Evidence showed that benign thyroid disease was one of the risk factors for thyroid cancer. However, the results of some studies were inconsistent and were previously meta-analyses of case–control studies. Therefore, we performed a meta-analysis of prospective studies to investigate the relationship between benign thyroid diseases and thyroid cancer risk.
Methods
All eligible studies were identified via systematic searches of multiple literature databases. The combined RR (relative risk)/HR (hazard ratio) or SIR (standardized incidence ratio) with 95% confidence interval was calculated. Heterogeneity was assessed with the I2 test. Publication bias and subgroup analyses were also performed.
Results
Twelve studies were eligible for inclusion in the meta-analysis. The pooled RR/HR of thyroid carcinoma in benign thyroid diseases was 4.39 (95% CI 3.22–5.55). The pooled SIR of thyroid carcinoma in benign thyroid diseases was 5.98 (95% CI 4.09–7.86). Subgroup analysis was performed using the type of benign thyroid diseases. Effect value was RR/HR: hyperthyroidism (RR/HR = 3.89, 95% CI = 1.69–6.08), hypothyroidism (RR/HR = 2.72, 95% CI = 1.04–4.41), and goiter (RR/HR = 22.18, 95% CI = 12.09–32.28). Effect value was SIR: hyperthyroidism (RR/HR = 5.96, 95% CI = 1.88–10.03), goiter (RR/HR = 7.65, 95% CI = 6.94–8.37), and thyroiditis (RR/HR = 3.25, 95% CI = 1.62–4.89).
Conclusions
Our study has shown that benign thyroid diseases might be associated with increased risk of thyroid cancer, especially in hyperthyroidism, hypothyroidism, and goiter. However, further investigation is needed to better understand the underlying biological mechanisms.
https://ift.tt/2JvV2HG
Modulation of Premetastatic Niche by the Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor Pazopanib in Localized High‐Risk Prostate Cancer Followed by Radical Prostatectomy: A Phase II Randomized Trial
Lessons Learned. Pazopanib was not effective in altering the premetastatic niche in the neoadjuvant setting.Pazopanib was safe and well tolerated without any new safety signals.Background.Vascular endothelial growth factor receptor 1 (VEGFR1) expressing myeloid‐derived suppressor cells (VEGFR1+ MDSCs) potentially foster metastases by establishing a premetastatic niche. In a preclinical study, VEGFR1+ clustering in lymph nodes (LNs) independently predicted time to biochemical recurrence (TTBR) in localized prostate cancer [1]. The hypothesis was that neoadjuvant pazopanib therapy will decrease VEGFR1+ clusters in pelvic lymph nodes and improve outcomes.Methods.This is a phase II trial (NCT01832259) of neoadjuvant pazopanib 800 mg versus placebo daily for 4 weeks in high‐risk localized prostate cancer. The primary endpoint was a decrease in VEGFR1+ MDSC clustering assessed by immunohistochemistry (IHC) analysis. Secondary endpoints were safety, feasibility, and TTBR.Results.Thirty patients were randomized to pazopanib versus placebo, with 15 patients randomized to each arm. Demographic and disease characteristics were similar in both arms. There was no difference in the VEGFR1+ clustering between the treatment arms (p = .345). Neoadjuvant therapy with pazopanib was well tolerated, and surgical complications were similar in both arms.Conclusion.Neoadjuvant pazopanib therapy did not alter the premetastatic niche; however, treatment targeting vascular endothelial growth factor (VEGF) in the preoperative period was safe and feasible, which may open up the avenue to investigate novel combinatorial regimens, including a VEGF inhibitor in combination with immune checkpoint inhibitor in this setting.
https://ift.tt/2DedO6h
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Ειδοποίηση Μελετητή:[ ωτα ] [HTML] Gender, identity and material: Film screening C Brand - 2017 ftypM4V *M4V M4A mp42isom*a┌moovlmvhd...
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Publication date: September 2017 Source: Free Radical Biology and Medicine, Volume 110 Author(s): Lucía Fernández-del-Río, Anish Nag, Elen...
