Computational Fluid Dynamics Upper Airway Effective Compliance, Critical Closing Pressure, and Obstructive Sleep Apnea Severity,Oral Appliance Therapy,The Effect Of Donepezil On Sleep Apnea In Patients With Obstructive Sleep Apnea,Obstructive Sleep Apnea With Retinal Microvascular Signs,Effect Of Positional Therapy On The Pharyngeal Structure Causing Collapse

Computational Fluid Dynamics Upper Airway Effective Compliance, Critical Closing Pressure, and Obstructive Sleep Apnea Severity in Obese Adolescent Girls

DM Wootton, S Sin, H Luo, A Yazdani, JM McDonough… - Journal of Applied …, 2016

Abstract Rationale: Obstructive sleep apnea syndrome (OSAS) is associated with
anatomical abnormalities restricting upper airway size and functional factors decreasing
pharyngeal dilator activity in sleep. In this study we hypothesized that OSAS is also ...

What role for hypercapnia in obstructive sleep apnea?

JV Brugniaux, GE Foster, AE Beaudin - Journal of Applied Physiology, 2016

to the editor: The question raised by Wang et al.(5) in their recent Viewpoint is important
inasmuch as apneic events in obstructive sleep apnea (OSA) are associated with both
hypoxia and hypercapnia. Given the cerebrovasculature is more sensitive to hypercapnia ...

The Use Of A Validated Claustrophobia Questionnaire In Predicting Future Compliance To Continuous Positive Airway Pressure (CPAP) In Obstructive Sleep Apnea ( …

K Agarwal, S Uppalapati, K Moss, L Bazan, C Drake… - D57. DON'T BE A DO- …, 2016

We performed a prospective chart review of 43 patients who were newly diagnosed with
OSA. During their consultation visit, patients were provided with a claustrophobia
questionnaire that measures fear of suffocation and fear of restriction. These ...

Montelukast for Children with Obstructive Sleep Apnea: Results of a Double-blind Randomized Placebo-controlled Trial

L Kheirandish-Gozal, HPR Bandla, D Gozal - Annals of the American Thoracic Society, 2016

Rationale: Obstructive sleep apnea (OSA) is highly prevalent in children and is usually
treated by adenotonsillectomy. Non-surgical therapies for OSA consist primarily of anti-
inflammatory approaches and have recently gained popularity, but their efficacy remains ...

Prediction Of Outcome With Oral Appliance Therapy For Obstructive Sleep Apnea Using In-home Mandibular Titration

Z Topor, J Grosse, N Vranjes, S Charkandeh… - D57. DON'T BE A DO- …, 2016

Methods Participants (N= 131; AHI> 10 hr-1) underwent a two night study with a computer-
controlled mandibular position that responded to respiratory events detected in real time,
and all received a custom oral appliance (SomnoMed or MicroO). Using prospectively ...

Management of obstructive sleep apnea in children: A practical approach.

KD Pereira, CK Jon, P Szmuk, RH Lazar, RB Mitchell - Ear, nose, & throat journal, 2016

The management of sleep disordered breathing (SDB) in children differs between
institutions, and there is a need for an updated review of current practice. Literature was
reviewed using the PubMed database from 1995 to 2015 by four tertiary care providers ...

Evaluating The Use Of Quality Care Measures In The Assessment And Management Of Obstructive Sleep Apnea Patients

C Ryan, N Uppal - D57. DON'T BE A DO-BADDER: NEW …, 2016

Methods: We performed a retrospective, cross-sectional study of all patients with OSA who
were seen for follow-up assessments in the Sleep Disorders clinic at TGH from September 1
2014 to April 30 2015. For those with a diagnosis of OSA based on diagnostic ...

The Effect Of Donepezil On Sleep Apnea In Patients With Obstructive Sleep Apnea-A Randomized, Double Blind Cross-Over Study

RL Owens, SA Sands, JE Orr, PN DeYoung, ET Smales… - D57. DON'T BE A DO- …, 2016

Rationale: obstructive sleep apnea (OSA). Prior small studies have shown that donepezil, an
acetylcholinesterase inhibitor, might improve OSA, possibly related to manipulation of ArTh,
ventilatory stability and/or muscular compensation. The hypothesis of this study is that a ...

Effect Of Positional Therapy On The Pharyngeal Structure Causing Collapse In Obstructive Sleep Apnea Patients

P Genta, SA Sands, A Azarbarzin, C De Melo… - D57. DON'T BE A DO- …, 2016

Supine sleep position usually worsens OSA severity. Among patients with positional OSA
(obstructive events predominantly while supine), avoiding supine position effectively treats
OSA. However, positional therapy is not effectively prescribed. If structure-specificity of ...

[HTML] Sex‐Specific Association of Obstructive Sleep Apnea With Retinal Microvascular Signs: The Multi‐Ethnic Study of Atherosclerosis

GM Lin, S Redline, R Klein, LA Colangelo, MF Cotch… - Journal of the American …, 2016

Background Obstructive sleep apnea (OSA) is a common condition affecting more men than
women. The relationship of OSA with microvascular disease is unclear, complicated by
possible sex difference. Assessment of the relationship of OSA with retinal microvascular ...