Mitochondria contribute to redox and calcium balance, and apoptosis thus regulating cellular fate. The described dye V07-07059 stains mitochondria effectively due to their membrane potential in vitro and in vivo. It further exhibits superior properties compared to currently used probes such as greater photostability and reduced cell toxicity. Therefore it is a novel tool for longitudinal and functional studies of mitochondria.
Further details can be found in the article by A. T. Press et al. on pp. 888–900.
http://ift.tt/2bXMdWS
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