Neuronal SOCE: Myth or Reality?

Publication date: Available online 6 October 2016
Source:Trends in Cell Biology
Author(s): Bo Lu, Marc Fivaz
Store-operated Ca²⁺ entry (SOCE) is the primary Ca²⁺ influx pathway in non-excitable cells. Long thought to be absent in nerve cells, neuronal SOCE is gaining popularity. We argue here that the evidence for SOCE in neurons remains contentious, mostly because SOCE imaging assays are inadequate in these cells.



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