Effects of DMSO on Rabbit Ear Hypertrophic Scar Model: A Controlled Randomized Experimental Study

Dimethylsulfoxide (DMSO) is an anti-inflammatory, anti-bacterial, analgesic drug that is widely used to treat several diseases in literature. It has a detractive effect to collagen deposition in abnormal tissue. The aim of this study was to investigate the possible therapeutic effects of the DMSO in the hypertrophic scar formation in rabbit.Twenty-four New Zealand male albino rabbits were randomly divided into four groups: control, sham, DMSO, and TRA (triamcinolone acetonide). Except control group, punch biopsy defects were created on each animal's right ear.

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