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Παρασκευή 3 Φεβρουαρίου 2017

Targeted therapy in older women with breast cancer – what’s the target?

Publication date: Available online 3 February 2017
Source:European Journal of Surgical Oncology (EJSO)
Author(s): Mandy Kiderlen, Cornelis J.H. van de Velde, Gerrit-Jan Liefers
In this review, the results of the FOCUS (Female breast cancer in the elderly: Optimizing Clinical guidelines USing clinico-pathological and molecular data) program are summarized. This study was originally designed with the aim to define guidelines for the treatment of older women with breast cancer. With data from several studies within FOCUS, a prediction model can be constructed. Such a model helps to define individualized treatment for older patients with breast cancer, taking into account tumour characteristics and patient-related factors. At a clinical level, his model can provide the physician and the patient with accurate prediction to assist on the decision making of treatment strategies: this results into individualized treatment, not based on one individual marker, but on different pillars related to the patient, the tumour and the most suitable, appropriate treatment.



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