West African Ebola Virus Strains: Unstable and Ready to Invade?

Publication date: 8 March 2017
Source:Cell Host & Microbe, Volume 21, Issue 3
Author(s): Christopher F. Basler
Recent studies demonstrate that the Ebola virus glycoprotein (GP) acquired an A82V change during the West Africa epidemic and that this change altered the capacity of GP to be activated by host factors, enhancing infection of human cells. How this may alter the outcome of disease remains to be determined.

Teaser

Recent studies demonstrate that the Ebola virus glycoprotein (GP) acquired an A82V change during the West Africa epidemic and that this change altered the capacity of GP to be activated by host factors, enhancing infection of human cells. How this may alter the outcome of disease remains to be determined.


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