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Κυριακή 7 Μαΐου 2017

Dedifferentiated chondrosarcoma with “adamantinoma-like” features: a case report and review of literature

Publication date: Available online 6 May 2017
Source:Pathology - Research and Practice
Author(s): M. Gambarotti, A. Righi, T. Frisoni, D. Donati, D. Vanel, M. Sbaraglia, A.P. Dei Tos
Dedifferentiated chondrosarcoma is defined by the presence of a low grade malignant cartilaginous component juxtaposed to a high grade malignant non-cartilaginous sarcomatous components. Only 4 cases in which the high grade component showed epithelial differentiation have been reported in the literature; three featured a squamous and the one a glandular epithelial component. Here we describe a case of dedifferentiated chondrosarcoma exhibiting epithelial "adamantinoma-like" basaloid features. The patient underwent wide resection of the proximal tibia and post-operative chemotherapy and died 8 months after the diagnosis due to lung and bone metastases.



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