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Παρασκευή 26 Μαΐου 2017

Neurochemical correlates of functional plasticity in the mature cortex of the brain of rodents

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Publication date: 28 July 2017
Source:Behavioural Brain Research, Volume 331
Author(s): Ewa Siucinska
It is commonly accepted that increase of input to sensory structures in mammals is known to produce marked changes in cortical recipient areas. This paper reviews the data concerning manifestations of changes in primary somatosensory cortex of adult animals caused by classical conditioning with reinforcement: aversive (whisker-shock) and appetitive (whisker-water) trainings. These include: anatomical, electrophysiological responses, receptor autoradiography, expression of GABA, GAD at mRNA and protein levels, expression of neuronal and astroglial GAT-1 puncta and inhibitory synaptogenesis in the hollows of "trained" barrels of the adult mouse. Here we have quoted the discovery in an earlier work of the creation of a picture of the extended perimeter of the neuronal mechanisms of coding and mediating in experience-dependent changes in the barrel cortex.



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