NICE DSU Technical Support Document 12: The Use of Health State Utility Values in Decision Models [Internet].

The National Institute for Health and Clinical Excellence (NICE) provides recommendations on health related quality of life (HRQoL) data used in submissions in their Guide to the Methods of Technology Appraisal. As different measures can produce different health state utility values (HSUV), the Institute state a preference for EQ-5D data to facilitate comparison across disease areas and interventions. However, inconsistencies in the methodologies used when applying HSUVs in economic models will produce discrepancies in results generated from decision analytic models, even when using the same measure, thus undermining policy decision making based on cost per quality adjusted life year (QALY) thresholds.

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