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Σάββατο 10 Ιουνίου 2017

Development of classification criteria for discoid lupus erythematosus: Results of a Delphi exercise

Publication date: Available online 9 June 2017
Source:Journal of the American Academy of Dermatology
Author(s): Scott A. Elman, Cara Joyce, Filippa Nyberg, Fukumi Furukawa, Mark Goodfield, Minoru Hasegawa, Branka Marinovic, Jacek C. Szepietowski, Jan Dutz, Victoria P. Werth, Joseph F. Merola
BackgroundNo classification criteria currently exist for discoid lupus erythematosus (DLE), which has led to problematic heterogeneity in both observational and interventional research efforts.ObjectivesWe sought to develop DLE classification criteria based on consensus of international expert opinion of relevant stakeholders in the field.MethodsUsing a Delphi consensus process and nominal group techniques, potential items for classification criteria were generated. Experts ranked items in terms of their appropriateness and ability to discriminate DLE from other diagnoses, and items were subsequently eliminated using consensus exercises.ResultsA final list of 12 clinical and histopathologic items was generated for potential inclusion into a set of DLE classification criteria through a formal ongoing validation process.LimitationsThe participants are predominantly composed of DLE experts in North America and Europe.ConclusionThis work represents a key step toward the development of formal DLE classification criteria.



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