Disease- or Storage-Associated Structural Modifications Are Unlikely to Explain HDL Pro-inflammatory Effects on Macrophages

Publication date: Available online 22 June 2017
Source:Cell Metabolism
Author(s): Emiel P.C. van der Vorst, Kosta Theodorou, Erik A.L. Biessen, Marjo M.P.C. Donners

Teaser

Van der Vorst et al. underscore the relevance of HDL quality control, considering HDL source and processing, but argue that disease- or storage-associated structural modifications of HDL cannot explain the observed pro-inflammatory effects on macrophages. Discrepancies between reported effects of HDL in macrophages are probably related to methodological differences.


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