Hepatic fat quantification using automated six-point Dixon: Comparison with conventional chemical shift based sequences and computed tomography

Publication date: Available online 20 June 2017
Source:Clinical Imaging
Author(s): Kie Shimizu, Tomohiro Namimoto, Masataka Nakagawa, Kosuke Morita, Seitaro Oda, Takeshi Nakaura, Daisuke Utsunomiya, Yasuyuki Yamashita
PurposeTo compare automated six-point Dixon (6-p-Dixon) MRI comparing with dual-echo chemical-shift-imaging (CSI) and CT for hepatic fat fraction in phantoms and clinical study.Materials and methodsPhantoms and fifty-nine patients were examined both MRI and CT for quantitative fat measurements.ResultsIn phantom study, linear regression between fat concentration and 6-p-Dixon showed good agreement. In clinical study, linear regression between 6-p-Dixon and dual-echo CSI showed good agreement. CT attenuation value was strongly correlated with 6-p-Dixon (R²=0.852; P<0.001) and dual-echo CSI (R²=0.812; P<0.001).ConclusionAutomated 6-p-Dixon and dual-echo CSI were accurate correlation with CT attenuation value of liver parenchyma. 6-p-Dixon has the potential for automated hepatic fat quantification.



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