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Τετάρτη 5 Ιουλίου 2017

Non-contrast-enhanced 3D MR portography within a breath-hold using compressed sensing acceleration: A prospective noninferiority study

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Publication date: Available online 5 July 2017
Source:Magnetic Resonance Imaging
Author(s): Ayako Ono, Shigeki Arizono, Koji Fujimoto, Thai Akasaka, Rikiya Yamashita, Akihiro Furuta, Hiroyoshi Isoda, Kaori Togashi
PurposeTo evaluate images of non-contrast-enhanced 3D MR portography within a breath-hold (BH) using compressed sensing (CS) compared to standard respiratory-triggered (RT) sequences.Materials and methodsFifty-nine healthy volunteers underwent MR portography using two sequences of balanced steady-state free-precession (bSSFP) with time-spatial labeling inversion pulses (Time-SLIP): BH bSSFP-CS and RT bSSFP. Two radiologists independently scored the diagnostic acceptability to delineate the portal branches (MPV: main portal vein; RPV: right portal vein; LPV: left portal vein; RPPV: right posterior portal vein; and P4 and P8: portal branch of segment 4 and segment 8, respectively) and the overall image quality on a four-point scale. We assessed noninferiority of BH bSSFP-CS to RT bSSFP. For quantitative analysis, vessel-to-liver contrast (Cv-l) was calculated in MPV, RPV and LPV.ResultsBH bSSFP sequence was successfully performed with a 30-second acquisition time. The diagnostic acceptability scores of BH bSSFP-CS compared with RT bSSFP were statistically noninferior: MPV (95% CI for score difference of Reader 1 and Reader 2, respectively: [−0.16, 0.06], [−0.05, 0.02]), RPV ([−0.00, 0.11], [−0.01, 0.08]), LPV ([−0.03, 0.10], [−0.10, 0.03]), RPPV ([−0.03, 0.10], [−0.05, 0.05]), P4 ([−0.13, 0.34], [−0.28, 0.21]) and P8 ([−0.21, 0.11], [−0.25, −0.02]). However, the overall image quality of BH bSSFP-CS did not show noninferiority ([−0.61, −0.24], [−0.54, −0.17]). Cv-l values were significantly lower in BH bSSFP-CS (P<0.001).ConclusionCS enabled non-contrast-enhanced 3D bSSFP MR portography to be performed within a BH while maintaining noninferior diagnostic acceptability compared to standard RT bSSFP MR portography.



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