In the Hunger Games, the Winner Takes Everything

Publication date: Available online 28 August 2017
Source:Trends in Biochemical Sciences
Author(s): Franziska Püschel, Cristina Muñoz-Pinedo
Entosis is an atypical form of cell death that occurs when a cell engulfs and kills another cell. A recent article by Overholtzer and colleagues indicates that glucose deprivation promotes entosis. AMP-activated protein kinase (AMPK) activation in the loser cells triggers their engulfment and elimination by winner cells, which endure starvation.



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