Abstract
We describe three cases of solar urticaria (SU) developing in patients with a diagnosis of Erythropoietic Protoporphyria (EPP). We suggest that this may imply that the endothelium may be the location of a chromophore in SU.
Patient 1 was a 42-year-old female. She had EPP characterised lifelong by three day long bouts of burning pain and swelling on the backs of hands and face induced by 10 minutes of exposure to spring or summer sun, and an increased red cell free protoporphyrin IX concentration (36micromol/L (normal range <0.2micromol/L)).
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