Effects of toothpastes on white spot lesions around orthodontic brackets using quantitative light-induced fluorescence (QLF)

Abstract

Aim

The aim of this study was to investigate the effects of toothpastes with different contents on the remineralization of white spot lesions around orthodontic brackets by quantitative light-induced fluorescence (QLF).

Materials and methods

A total of 45 freshly extracted human mandibular first molars were selected. Artificial caries lesions were created on enamel surfaces using an acidified gel system for 7 days. Initial relative fluorescence loss was calculated as the pretreatment (baseline) fluorescence value by QLF device. Molar tubes were bonded using light-cured resin composite cement. The specimens were randomly divided into three experimental groups (n = 15). Different toothpastes were applied to demineralized enamel: (1) fluoride-containing toothpaste (Colgate Total^®), (2) Novamin-containing toothpaste (Sensodyne^® Repair and Protect), (3) probiotic-containing toothpaste (GD Probiotic Toothpaste^®). After 2 weeks of treatment, fluorescence loss and lesion area were measured with QLF. To determine fluorescence changes, intergroup comparisons were performed with a multivariate analysis of variance, followed by Tukey's test at a probability value of p < 0.05.

Results

Significant differences were observed between initial and posttreatment QLF measurements of the demineralized enamel specimens treated with the various agents (p < 0.05). In all experimental groups, significant fluorescence radiance increase and decrease of the lesion area (p = 0.000) was found.

Conclusion

Novamin-containing toothpaste provided more increase of fluorescence compared to fluoride- and probiotic-containing toothpastes.

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