TrkA Bumps into Its Future Self

Publication date: 25 September 2017
Source:Developmental Cell, Volume 42, Issue 6
Author(s): Kelly Barford, Austin Keeler, Christopher Deppmann, Bettina Winckler
In neurons, correct targeting of receptors to the axon is critical for cell survival and circuit formation. In this issue of Developmental Cell, Yamashita et al. (2017) report that the ER-resident phosphatase PTP1B is required to prime TrkA for axonal transport.

Teaser

In neurons, correct targeting of receptors to the axon is critical for cell survival and circuit formation. In this issue of Developmental Cell, Yamashita et al. (2017) report that the ER-resident phosphatase PTP1B is required to prime TrkA for axonal transport.


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