General Xenobiochemistry Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA
Poonam Giri, Prashant Delvadia, Laxmikant Gupta, Nirmal Patel, Priyal Trivedi, Krishna Lad, Hiren M. Patel & Nuggehally R. Srinivas
Pages: 1-10 | DOI: 10.1080/00498254.2016.1275064
Animal Pharmacokinetics and Metabolism Two sulfonate metabolites of physalin A in rats
Hongxia Liu, Kai Wang, Guiyang Xia, Kun Wang, Liwei Chai, Paul Owusu Donkor, Liqin Ding & Feng Qiu
Pages: 11-17 | DOI: 10.1080/00498254.2016.1271961
Comparative pharmacokinetics between madecassoside and asiaticoside presented in a standardised extract of Centella asiatica, ECa 233 and their respective pure compound given separately in rats
Patcharaporn Hengjumrut, Tosapol Anukunwithaya, Mayuree H. Tantisira, Boonyong Tantisira & Phisit Khemawoot
Pages: 18-27 | DOI: 10.1080/00498254.2016.1273562
Pharmacokinetics and tissue distribution of crotonoside
Peiao Yan, Lan Zhang, Cheng Peng & Ruoqi Zhang
Pages: 28-36 | DOI: 10.1080/00498254.2016.1276311
Influence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic kidney disease-induced anemia
Harilal Patel, Amit Arvind Joharapurkar, Vrajesh Bhaskarbhai Pandya, Vishal Jagjivanbhai Patel, Samadhan Govind Kshirsagar, Prakash Patel, Bhavesh Gevriya, Mukul R. Jain, Nuggehally R. Srinivas, Pankaj Ramanbhai Patel & Ranjit C. Desai
Pages: 37-44 | DOI: 10.1080/00498254.2016.1278287
Pharmacokinetic interaction of aconitine, liquiritin and 6-gingerol in a traditional Chinese herbal formula, Sini Decoction
Sen Sun, Qingshan Chen, Jiyun Ge, Xiang Liu, Xinxia Wang, Qi Zhan, Hai Zhang & Guoqing Zhang
Pages: 45-52 | DOI: 10.1080/00498254.2017.1278807
Altered tolbutamide pharmacokinetics by a decrease in hepatic expression of CYP2C6/11 in rats pretreated with 5-fluorouracil
Shuhei Fukuno, Katsuhito Nagai, Keita Kasahara, Yuki Mizobata, Sachiko Omotani, Yasutoshi Hatsuda, Michiaki Myotoku & Hiroki Konishi
Pages: 53-59 | DOI: 10.1080/00498254.2017.1278808
Molecular Toxicology Contributions of caspase-8 and -9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons
Yoshio Ijiri, Ryuji Kato, Maiko Sadamatsu, Mina Takano, Yuki Yasuda, Fumiaki Tanaka, Chiyo Oishi, Hideki Imano, Yoshikatsu Okada, Kazuhiko Tanaka & Tetsuya Hayashi
Pages: 60-72 | DOI: 10.1080/00498254.2016.1275881
Xenobiotic Transporters Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3
Toshihiro Sato, Hajime Ito, Ayaka Hirata, Takaaki Abe, Nariyasu Mano & Hiroaki Yamaguchi
Pages: 73-78 | DOI: 10.1080/00498254.2016.1275880
Pharmacogenetics A high frequency missense SULT1B1 allelic variant (L145V) selectively expressed in African descendants exhibits altered kinetic properties
Zachary E. Tibbs, Amber L. Guidry, Josie L. Falany, Susan A. Kadlubar & Charles N. Falany
Pages: 79-88 | DOI: 10.1080/00498254.2017.1282646
Topics in Xenobiochemistry Reappraisal and perspectives of clinical drug–drug interaction potential of α-glucosidase inhibitors such as acarbose, voglibose and miglitol in the treatment of type 2 diabetes mellitus
Ranjeet Prasad Dash, R. Jayachandra Babu & Nuggehally R. Srinivas
Pages: 89-108 | DOI: 10.1080/00498254.2016.1275063
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