Comparative diagnostic accuracy of dual-energy CT myocardial perfusion imaging by monochromatic energy versus material decomposition methods

Publication date: July–August 2018
Source:Clinical Imaging, Volume 50
Author(s): Ibrahim Danad, Iksung Cho, Kimberly Elmore, Joshua Schulman-Marcus, Bríain ó Hartaigh, Wijnand J. Stuijfzand, Patricia Carrascosa, James K. Min
PurposeTo compare the diagnostic value of monochromatic and material decomposition (MD) dual- energy computed tomography (DECT) imaging for the evaluation of ischemia.MethodsPatients with suspected coronary artery disease underwent rest-stress DECT and SPECT perfusion imaging. DECT images were reconstructed between 40 and 140keV and through MD of iodine/muscle.ResultsMD and monochromatic imaging had a sensitivity, specificity, negative predictive, positive predictive value, and accuracy of 89%, 40%, 67%, 73% and 71%; and 91%, 67%, 67%, 91% and 86%, respectively (p=0.05).ConclusionDECT using monochromatic energy displayed a non-significantly higher diagnostic accuracy for myocardial ischemia as compared with DECT MD.



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